TB-Profiler result

Run: SRR13861439
Summary

Run ID: SRR13861439

Sample name:

Date: 03-04-2023 09:31:46

Number of reads: 342830

Percentage reads mapped: 5.72

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761131 p.Gly442Glu missense_variant 0.62 rifampicin
embB 4247448 p.His312Arg missense_variant 0.17 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6824 c.-478C>T upstream_gene_variant 0.18
gyrA 6841 c.-461T>C upstream_gene_variant 0.17
gyrA 6844 c.-458T>G upstream_gene_variant 0.18
gyrA 6853 c.-449A>G upstream_gene_variant 0.18
gyrA 6856 c.-446T>C upstream_gene_variant 0.18
gyrA 6859 c.-443T>C upstream_gene_variant 0.18
gyrA 6862 c.-440C>G upstream_gene_variant 0.18
gyrA 6878 c.-424T>C upstream_gene_variant 0.17
gyrA 6881 c.-421T>C upstream_gene_variant 0.17
gyrA 6904 c.-398C>G upstream_gene_variant 0.17
gyrA 6919 c.-383T>C upstream_gene_variant 0.2
gyrA 8156 c.855T>C synonymous_variant 0.33
gyrA 8168 c.867A>G synonymous_variant 0.2
gyrA 8174 c.873C>G synonymous_variant 0.18
gyrA 8177 c.876A>C synonymous_variant 0.17
gyrA 8198 c.897T>C synonymous_variant 0.2
gyrA 8204 c.903C>T synonymous_variant 0.2
gyrA 8207 c.906T>C synonymous_variant 0.2
gyrA 8216 c.915G>A synonymous_variant 0.2
gyrA 8219 c.918T>C synonymous_variant 0.2
gyrA 8225 c.924T>C synonymous_variant 0.18
gyrA 8234 c.933T>G synonymous_variant 0.2
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.2
gyrA 8253 p.Ile318Leu missense_variant 0.22
gyrA 8264 c.963T>C synonymous_variant 0.2
gyrA 8619 c.1318T>C synonymous_variant 0.17
gyrA 8624 c.1323G>C synonymous_variant 0.17
gyrA 8627 c.1326C>G synonymous_variant 0.18
gyrA 8636 c.1335A>G synonymous_variant 0.18
gyrA 8645 c.1344C>G synonymous_variant 0.17
gyrA 8672 c.1371A>G synonymous_variant 0.2
gyrA 8693 c.1392T>C synonymous_variant 0.2
gyrA 8699 c.1398A>G synonymous_variant 0.22
gyrA 8711 c.1410A>C synonymous_variant 0.22
gyrA 8714 c.1413A>G synonymous_variant 0.2
gyrA 8717 c.1416C>G synonymous_variant 0.18
gyrA 8720 c.1419G>A synonymous_variant 0.18
gyrA 8729 c.1428T>C synonymous_variant 0.21
gyrA 8732 c.1431G>C synonymous_variant 0.21
gyrA 8747 c.1446A>G synonymous_variant 0.25
gyrA 8756 c.1455A>G synonymous_variant 0.31
gyrA 8762 c.1461G>C synonymous_variant 0.27
gyrA 8765 p.Asp488Glu missense_variant 0.2
gyrA 8767 p.Arg489Lys missense_variant 0.2
gyrA 8779 p.Asp493Ala missense_variant 0.23
gyrA 8786 c.1485T>C synonymous_variant 0.23
gyrA 8796 p.Ile499Val missense_variant 0.25
gyrA 8801 c.1500G>C synonymous_variant 0.25
gyrA 8810 c.1509A>C synonymous_variant 0.27
gyrA 8816 c.1515C>T synonymous_variant 0.27
gyrA 8829 c.1528T>C synonymous_variant 0.27
gyrA 8837 c.1536C>T synonymous_variant 0.23
gyrA 8852 c.1551T>C synonymous_variant 0.31
gyrA 8858 c.1557T>C synonymous_variant 0.29
gyrA 8867 c.1566A>G synonymous_variant 0.27
gyrA 8870 c.1569G>C synonymous_variant 0.27
gyrA 8873 c.1572A>C synonymous_variant 0.33
gyrA 8897 c.1596T>C synonymous_variant 0.25
gyrA 8903 c.1602T>C synonymous_variant 0.18
gyrA 8915 c.1614A>G synonymous_variant 0.18
gyrA 8987 c.1686C>G synonymous_variant 0.17
ccsA 620661 c.771C>G synonymous_variant 0.2
ccsA 620703 c.813G>C synonymous_variant 0.2
ccsA 620710 p.Val274Ile missense_variant 0.2
ccsA 620718 c.828G>C synonymous_variant 0.21
ccsA 620721 c.831G>C synonymous_variant 0.21
ccsA 620730 c.840C>T synonymous_variant 0.23
ccsA 620733 c.843G>C synonymous_variant 0.23
ccsA 620739 c.849A>G synonymous_variant 0.23
ccsA 620745 c.855G>C synonymous_variant 0.23
ccsA 620748 c.858T>A synonymous_variant 0.23
ccsA 620778 c.888T>C synonymous_variant 0.21
ccsA 620784 c.894C>G synonymous_variant 0.23
ccsA 620787 c.897C>G synonymous_variant 0.27
rpoB 761015 c.1209G>C synonymous_variant 0.29
rpoB 761021 c.1215G>C synonymous_variant 0.29
rpoB 761027 c.1221A>G synonymous_variant 0.29
rpoB 761036 c.1230G>C synonymous_variant 0.33
rpoB 761102 c.1296A>G synonymous_variant 0.33
rpoB 761126 c.1320G>T synonymous_variant 0.62
rpoB 761129 c.1323G>C synonymous_variant 0.67
rpoB 761133 p.Leu443Ile missense_variant 0.73
rpoB 761150 c.1344A>C synonymous_variant 0.71
rpoB 761151 p.Leu449Val missense_variant 0.57
rpoB 761156 c.1350G>C synonymous_variant 0.57
rpoB 761162 c.1356G>C synonymous_variant 0.5
rpoB 761165 c.1359G>C synonymous_variant 0.6
rpoB 761168 c.1362C>G synonymous_variant 0.56
rpoB 761178 p.Ser458Thr missense_variant 0.5
rpoB 761192 c.1386C>G synonymous_variant 0.5
rpoB 761195 c.1389G>C synonymous_variant 0.53
rpoB 761196 p.Leu464Phe missense_variant 0.53
rpoB 761204 c.1398C>T synonymous_variant 0.5
rpoB 761207 c.1401C>T synonymous_variant 0.53
rpoB 761213 c.1407G>A synonymous_variant 0.53
rpoB 761220 p.Ser472Thr missense_variant 0.53
rpoB 761234 c.1428G>C synonymous_variant 0.47
rpoB 761235 p.Met477Val missense_variant 0.47
rpoB 761258 c.1452G>A synonymous_variant 0.25
rpoC 763858 c.489A>G synonymous_variant 0.22
rpoC 763872 p.Gly168Ala missense_variant 0.18
rpoC 763876 p.Glu169Asp missense_variant 0.2
rpoC 763879 c.510A>G synonymous_variant 0.22
rpoC 763888 c.519G>C synonymous_variant 0.18
rpoC 763891 c.522G>C synonymous_variant 0.18
rpoC 763894 c.525A>G synonymous_variant 0.18
rpoC 763919 c.550C>T synonymous_variant 0.21
rpoC 763933 c.564C>T synonymous_variant 0.2
rpoC 763945 c.576T>C synonymous_variant 0.23
rpoC 763960 c.591T>C synonymous_variant 0.21
rpoC 763967 p.Gly200Ser missense_variant 0.19
rpoC 763978 c.609C>G synonymous_variant 0.2
rpoC 763996 c.627T>C synonymous_variant 0.17
rpoC 764005 c.636G>C synonymous_variant 0.18
rpoC 764011 c.642T>C synonymous_variant 0.18
rpoC 764024 c.655T>C synonymous_variant 0.19
rpoC 764040 p.Ser224Asn missense_variant 0.2
rpoC 764044 c.675T>C synonymous_variant 0.2
rpoC 764405 c.1036A>C synonymous_variant 0.15
rpoC 764521 c.1152T>C synonymous_variant 0.18
rpoC 765319 c.1950A>G synonymous_variant 0.17
rpoC 765326 p.His653Ala missense_variant 0.17
rpoC 765330 p.Ser654Asn missense_variant 0.18
rpoC 765349 c.1980T>C synonymous_variant 0.15
rpoC 765352 c.1983G>C synonymous_variant 0.15
rpoC 765383 p.Met672Leu missense_variant 0.2
rpoC 765404 p.Leu679Val missense_variant 0.22
rpoC 765409 c.2040T>C synonymous_variant 0.25
rpoC 765412 c.2043T>C synonymous_variant 0.25
rpoC 765421 c.2052C>G synonymous_variant 0.25
rpoC 765979 c.2610C>G synonymous_variant 0.18
rpoC 765982 c.2613C>T synonymous_variant 0.18
rpoC 765985 c.2616C>T synonymous_variant 0.2
rpoC 765994 c.2625A>T synonymous_variant 0.22
rpoC 766009 c.2640G>C synonymous_variant 0.18
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.18
rpoC 766021 c.2652G>C synonymous_variant 0.17
rpoC 766043 p.Gln892Glu missense_variant 0.17
rpoC 766054 c.2685C>G synonymous_variant 0.17
rpoC 766069 c.2700G>A synonymous_variant 0.15
rpoC 766082 p.Ala905Gln missense_variant 0.17
rpoC 766096 c.2727G>C synonymous_variant 0.18
rpoC 766105 c.2736C>T synonymous_variant 0.18
rpoC 766843 c.3474T>C synonymous_variant 0.17
rpoC 766861 c.3492G>C synonymous_variant 0.25
rpoC 766864 c.3495G>C synonymous_variant 0.27
rpoC 766894 c.3525T>C synonymous_variant 0.23
rpoC 766895 c.3526T>C synonymous_variant 0.23
rpoC 766900 c.3531T>C synonymous_variant 0.21
rpoC 766933 c.3564A>G synonymous_variant 0.27
rpoC 766945 c.3576A>G synonymous_variant 0.21
rpoC 766963 c.3594T>C synonymous_variant 0.18
rpoC 766978 c.3609C>G synonymous_variant 0.2
rpoC 766996 c.3627C>T synonymous_variant 0.19
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.14
rpoC 767014 c.3645G>C synonymous_variant 0.14
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.23
rpoC 767059 c.3690T>G synonymous_variant 0.18
rpoC 767062 c.3693C>A synonymous_variant 0.18
rpoC 767074 c.3705T>C synonymous_variant 0.18
rpoC 767098 c.3729T>C synonymous_variant 0.22
rpoC 767119 c.3750A>G synonymous_variant 0.2
rpsL 781649 c.90T>C synonymous_variant 0.18
rpsL 781655 c.96T>C synonymous_variant 0.2
rpsL 781682 c.123T>C synonymous_variant 0.2
rpsL 781715 c.156T>C synonymous_variant 0.22
rpsL 781728 c.169T>C synonymous_variant 0.25
rpsL 781751 c.192G>C synonymous_variant 0.22
rpsL 781754 c.195G>C synonymous_variant 0.22
rpsL 781760 c.201T>C synonymous_variant 0.2
fbiC 1305276 c.2346G>C synonymous_variant 0.15
fbiC 1305279 p.His783Gln missense_variant 0.15
fbiC 1305282 c.2352T>C synonymous_variant 0.15
fbiC 1305297 c.2367G>C synonymous_variant 0.15
fbiC 1305300 c.2370A>G synonymous_variant 0.15
fbiC 1305303 c.2373T>C synonymous_variant 0.15
fbiC 1305311 p.Arg794Gln missense_variant 0.14
fbiC 1305331 p.Glu801Asn missense_variant 0.15
fbiC 1305336 c.2406T>C synonymous_variant 0.15
fbiC 1305381 c.2451G>C synonymous_variant 0.18
fbiC 1305393 c.2463T>C synonymous_variant 0.17
fbiC 1305405 c.2475A>G synonymous_variant 0.15
fbiC 1305411 c.2481C>T synonymous_variant 0.15
fbiC 1305420 c.2490C>G synonymous_variant 0.17
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.22
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.25
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.25
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.2
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.67
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.71
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.71
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.71
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.71
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.69
rrs 1472971 n.1126G>C non_coding_transcript_exon_variant 0.68
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.69
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.68
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.66
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.62
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.67
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.69
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.69
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.66
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.69
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.7
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.59
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.59
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.18
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.18
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.18
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.17
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.15
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.27
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.27
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.31
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.33
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.27
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.27
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.22
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.18
rrl 1473945 n.288T>C non_coding_transcript_exon_variant 0.18
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.18
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.18
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.18
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.2
rrl 1474051 n.394T>C non_coding_transcript_exon_variant 0.25
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.25
rrl 1474056 n.399T>C non_coding_transcript_exon_variant 0.25
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.2
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.18
rrl 1474112 n.455T>A non_coding_transcript_exon_variant 0.18
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.22
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.22
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.3
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.22
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.33
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.3
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.5
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.5
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.5
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.5
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.25
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.17
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.21
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.14
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.15
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.23
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.79
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.81
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.81
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.81
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.82
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.85
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.84
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.83
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.83
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.85
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.83
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.83
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.84
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.85
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.85
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.85
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.86
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.85
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.84
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.83
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.58
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.21
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.3
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.27
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.27
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.25
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.25
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.25
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.25
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.25
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.29
inhA 1673574 c.-628C>G upstream_gene_variant 0.14
inhA 1673580 c.-622T>C upstream_gene_variant 0.14
inhA 1673589 c.-613A>G upstream_gene_variant 0.15
fabG1 1673596 p.Lys53Asp missense_variant 0.13
fabG1 1673633 p.Ser65Asn missense_variant 0.13
inhA 1673646 c.-556T>C upstream_gene_variant 0.13
inhA 1674368 p.Ala56Glu missense_variant 0.33
inhA 1674379 c.178C>T synonymous_variant 0.29
inhA 1674382 p.Leu61Ile missense_variant 0.29
inhA 1674387 c.186A>G synonymous_variant 0.25
inhA 1674399 c.198A>G synonymous_variant 0.22
inhA 1674480 c.279T>C synonymous_variant 0.3
inhA 1674486 c.285T>C synonymous_variant 0.3
inhA 1674489 c.288G>C synonymous_variant 0.3
inhA 1674498 c.297G>A synonymous_variant 0.3
inhA 1674507 c.306G>C synonymous_variant 0.18
inhA 1674537 c.336C>G synonymous_variant 0.2
inhA 1674542 p.Ala114Glu missense_variant 0.2
inhA 1674549 c.348G>C synonymous_variant 0.22
inhA 1674555 c.354G>A synonymous_variant 0.3
inhA 1674561 c.360C>T synonymous_variant 0.3
inhA 1674564 c.363C>T synonymous_variant 0.27
inhA 1674582 c.381T>C synonymous_variant 0.33
inhA 1674585 c.384T>C synonymous_variant 0.33
inhA 1674589 p.Met130Leu missense_variant 0.4
inhA 1674624 c.423A>C synonymous_variant 0.21
inhA 1674627 c.426T>G synonymous_variant 0.15
inhA 1674630 c.429C>G synonymous_variant 0.15
inhA 1674636 c.435C>G synonymous_variant 0.15
inhA 1674693 c.492C>G synonymous_variant 0.15
rpsA 1833851 p.Lys104Gln missense_variant 1.0
ndh 2101915 c.1128T>C synonymous_variant 0.17
ndh 2101918 p.Arg375Ser missense_variant 0.15
ndh 2101924 c.1119T>G synonymous_variant 0.17
ndh 2101939 c.1104A>C synonymous_variant 0.17
ndh 2101960 c.1083A>G synonymous_variant 0.18
ndh 2101966 c.1077T>G synonymous_variant 0.2
ndh 2101972 c.1071G>C synonymous_variant 0.2
ndh 2101978 p.Asn355Asp missense_variant 0.2
ndh 2101988 p.Ala352Gly missense_variant 0.18
ndh 2102009 p.Ser345Asn missense_variant 0.18
ndh 2102020 c.1023A>G synonymous_variant 0.18
ndh 2102023 c.1020G>C synonymous_variant 0.17
katG 2155716 c.396T>C synonymous_variant 0.22
katG 2155722 c.390G>C synonymous_variant 0.22
katG 2155740 p.Gly124Gln missense_variant 0.22
katG 2155747 p.Ala122Gly missense_variant 0.25
katG 2155782 c.330C>G synonymous_variant 0.29
Rv1979c 2223241 c.-77C>G upstream_gene_variant 1.0
pncA 2289811 c.-570C>T upstream_gene_variant 1.0
pncA 2289994 c.-753A>C upstream_gene_variant 1.0
kasA 2518301 p.His63Asp missense_variant 1.0
ahpC 2726579 c.387T>C synonymous_variant 0.15
ahpC 2726591 c.399C>G synonymous_variant 0.15
ahpC 2726593 p.Val134Ala missense_variant 0.15
ahpC 2726600 c.408T>C synonymous_variant 0.15
ahpC 2726612 c.420C>G synonymous_variant 0.14
ahpC 2726638 p.Ala149Val missense_variant 0.14
ahpC 2726645 c.453C>G synonymous_variant 0.15
ahpC 2726657 c.465A>C synonymous_variant 0.15
ahpC 2726669 p.Asp159Glu missense_variant 0.15
ahpC 2726672 c.480G>A synonymous_variant 0.17
ahpC 2726675 c.483A>G synonymous_variant 0.18
ahpC 2726681 c.489A>G synonymous_variant 0.18
pepQ 2859859 p.Ala187Glu missense_variant 1.0
Rv2752c 3064886 p.Ala436Pro missense_variant 1.0
Rv2752c 3064928 c.1264T>C synonymous_variant 0.2
Rv2752c 3064932 c.1260T>C synonymous_variant 0.2
Rv2752c 3064935 c.1257A>G synonymous_variant 0.2
Rv2752c 3064941 p.Gln417Glu missense_variant 0.18
Rv2752c 3064947 c.1245A>G synonymous_variant 0.18
Rv2752c 3064956 p.Ser412Arg missense_variant 0.18
Rv2752c 3064962 c.1230C>A synonymous_variant 0.18
Rv2752c 3064973 p.Ala407Ser missense_variant 0.17
Rv2752c 3064974 c.1218T>C synonymous_variant 0.17
Rv2752c 3064980 c.1212C>G synonymous_variant 0.17
Rv2752c 3064995 c.1197C>G synonymous_variant 0.15
Rv2752c 3064998 c.1194A>G synonymous_variant 0.14
Rv2752c 3065018 p.Asn392His missense_variant 0.14
Rv2752c 3065028 c.1164G>C synonymous_variant 0.14
Rv2752c 3065031 c.1161G>C synonymous_variant 0.14
Rv2752c 3065040 c.1152C>G synonymous_variant 0.21
Rv2752c 3065048 c.1144C>T synonymous_variant 0.17
Rv2752c 3065064 c.1128G>C synonymous_variant 0.17
Rv2752c 3065258 p.Met312Val missense_variant 1.0
thyX 3067640 c.306G>C synonymous_variant 0.17
thyX 3067643 c.303C>T synonymous_variant 0.17
thyX 3067652 c.294T>C synonymous_variant 0.18
thyX 3067661 c.285C>G synonymous_variant 0.18
thyX 3067682 c.264G>C synonymous_variant 0.2
thyX 3067685 c.261A>G synonymous_variant 0.18
thyX 3067688 c.258G>C synonymous_variant 0.18
thyX 3067694 c.252G>C synonymous_variant 0.17
thyX 3067718 c.228C>G synonymous_variant 0.15
thyX 3067721 c.225T>C synonymous_variant 0.15
thyX 3067724 c.222G>A synonymous_variant 0.15
thyX 3067727 c.219A>C synonymous_variant 0.15
thyX 3067761 p.Arg62Lys missense_variant 0.21
thyX 3067765 p.Leu61Ile missense_variant 0.21
thyX 3067802 c.144C>G synonymous_variant 0.13
thyX 3067814 c.132T>C synonymous_variant 0.12
thyX 3067874 c.72C>A synonymous_variant 0.18
thyA 3073953 c.519T>C synonymous_variant 0.15
thyA 3073989 c.483T>C synonymous_variant 0.15
Rv3083 3449104 p.Pro201Ala missense_variant 1.0
Rv3236c 3612337 c.779delG frameshift_variant 1.0
fbiA 3640902 p.Gln120His missense_variant 0.25
fbiB 3641723 c.189T>C synonymous_variant 1.0
rpoA 3877740 c.768G>T synonymous_variant 0.85
rpoA 3877818 c.690A>G synonymous_variant 0.2
rpoA 3877839 c.669G>C synonymous_variant 0.2
rpoA 3877953 c.555G>A synonymous_variant 0.2
rpoA 3877962 c.546G>T synonymous_variant 0.2
rpoA 3877986 c.522G>C synonymous_variant 0.14
rpoA 3878001 c.507A>G synonymous_variant 0.17
rpoA 3878055 c.453A>G synonymous_variant 0.18
rpoA 3878061 c.447G>C synonymous_variant 0.22
rpoA 3878067 c.441C>G synonymous_variant 0.22
rpoA 3878070 c.438T>C synonymous_variant 0.22
rpoA 3878118 c.390T>C synonymous_variant 0.25
rpoA 3878141 p.Met123Leu missense_variant 0.25
rpoA 3878142 p.Gly122Glu missense_variant 0.25
rpoA 3878169 c.339G>C synonymous_variant 0.23
rpoA 3878184 c.324C>T synonymous_variant 0.31
rpoA 3878187 c.321C>G synonymous_variant 0.31
rpoA 3878193 c.315T>C synonymous_variant 0.31
rpoA 3878199 c.309T>C synonymous_variant 0.31
rpoA 3878202 c.306G>C synonymous_variant 0.25
rpoA 3878217 c.291A>G synonymous_variant 0.27
rpoA 3878220 c.288C>T synonymous_variant 0.27
rpoA 3878304 c.204G>C synonymous_variant 0.17
rpoA 3878313 c.195G>C synonymous_variant 0.17
rpoA 3878322 c.186A>G synonymous_variant 0.2
rpoA 3878442 c.66G>C synonymous_variant 0.15
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.17
clpC1 4040093 c.612C>G synonymous_variant 0.17
clpC1 4040105 c.600C>G synonymous_variant 0.17
clpC1 4040147 c.558A>G synonymous_variant 0.2
clpC1 4040153 c.552A>G synonymous_variant 0.2
clpC1 4040162 c.543G>C synonymous_variant 0.17
clpC1 4040165 c.540G>C synonymous_variant 0.17
clpC1 4040168 c.537G>C synonymous_variant 0.18
clpC1 4040171 c.534C>G synonymous_variant 0.22
clpC1 4040522 c.183T>C synonymous_variant 0.2
clpC1 4040528 c.177G>C synonymous_variant 0.17
clpC1 4040531 c.174T>C synonymous_variant 0.18
clpC1 4040534 c.171A>G synonymous_variant 0.17
clpC1 4040546 c.159G>C synonymous_variant 0.18
clpC1 4040551 c.154T>C synonymous_variant 0.17
clpC1 4040561 c.144A>G synonymous_variant 0.18
clpC1 4040570 c.135C>G synonymous_variant 0.17
clpC1 4040573 c.132T>G synonymous_variant 0.17
clpC1 4040579 c.126A>G synonymous_variant 0.17
clpC1 4040582 c.123G>C synonymous_variant 0.17
clpC1 4040588 c.117T>C synonymous_variant 0.15
clpC1 4040596 c.109C>T synonymous_variant 0.14
clpC1 4040597 c.108C>T synonymous_variant 0.14
embC 4240780 c.918T>C synonymous_variant 0.14
embC 4240783 c.921G>C synonymous_variant 0.14
embC 4240819 c.957A>G synonymous_variant 0.13
embC 4240825 c.963G>A synonymous_variant 0.13
embC 4240966 c.1104G>T synonymous_variant 0.13
embC 4240979 p.Thr373Gln missense_variant 0.13
embC 4240983 p.Ser374Asn missense_variant 0.13
embC 4240990 c.1128A>G synonymous_variant 0.14
embC 4241005 c.1143G>T synonymous_variant 0.87
embC 4241017 c.1155T>C synonymous_variant 0.13
embC 4241050 c.1188T>G synonymous_variant 0.17
embC 4241081 c.1220delT frameshift_variant 0.87
embC 4242746 p.Pro962Ser missense_variant 1.0
embA 4243969 p.Val246Ala missense_variant 1.0
embB 4246250 c.-264G>C upstream_gene_variant 0.2
embA 4246264 p.His1011Arg missense_variant 0.18
embB 4246274 c.-240G>C upstream_gene_variant 0.18
embB 4246292 c.-222A>G upstream_gene_variant 0.17
embA 4246308 c.3076_3077insAG frameshift_variant 0.22
embB 4246316 c.-198T>G upstream_gene_variant 0.2
embA 4246329 p.Thr1033Leu missense_variant 0.2
embB 4246355 c.-159G>C upstream_gene_variant 0.17
embA 4246359 p.Ala1043Pro missense_variant 0.17
embB 4246364 c.-150G>C upstream_gene_variant 0.15
embB 4246367 c.-147C>T upstream_gene_variant 0.14
embB 4246373 c.-141T>C upstream_gene_variant 0.15
embB 4246376 c.-138G>C upstream_gene_variant 0.15
embB 4247395 c.882C>G synonymous_variant 0.17
embB 4247401 c.888T>C synonymous_variant 0.17
embB 4247437 c.924A>G synonymous_variant 0.17
embB 4247440 c.927C>G synonymous_variant 0.17
embB 4247464 c.951C>G synonymous_variant 0.14
embB 4247470 c.957T>C synonymous_variant 0.15
embB 4247491 c.978G>C synonymous_variant 0.14
embB 4247497 c.984T>C synonymous_variant 0.14
embB 4247500 c.987C>G synonymous_variant 0.14
embB 4247512 c.999T>C synonymous_variant 0.14
embB 4247842 c.1329T>C synonymous_variant 0.22
aftB 4268446 p.Ala131Ser missense_variant 0.15
aftB 4268793 p.Val15Gly missense_variant 0.17