Run ID: SRR15316421
Sample name:
Date: 03-04-2023 13:30:34
Number of reads: 8841605
Percentage reads mapped: 99.5
Strain: lineage4.2.2
Drug-resistance: MDR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.2 | Euro-American | H;T;LAM | None | 1.0 |
lineage4.2.2 | Euro-American (Ural) | T;LAM7-TUR | None | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761140 | p.His445Arg | missense_variant | 1.0 | rifampicin |
rpoB | 761149 | p.Arg448Gln | missense_variant | 1.0 | rifampicin |
katG | 2155729 | p.Arg128Pro | missense_variant | 1.0 | isoniazid |
pncA | 2288826 | p.Val139Ala | missense_variant | 1.0 | pyrazinamide |
embB | 4247431 | p.Met306Ile | missense_variant | 1.0 | ethambutol |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
mshA | 576077 | c.730C>T | synonymous_variant | 1.0 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rpsA | 1833747 | p.Ser69Phe | missense_variant | 1.0 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
kasA | 2518496 | c.382C>T | synonymous_variant | 0.99 |
ahpC | 2726146 | c.-47_-46insT | upstream_gene_variant | 0.99 |
folC | 2746849 | c.750G>A | synonymous_variant | 0.99 |
ribD | 2987166 | p.Gly110Ser | missense_variant | 1.0 |
Rv2752c | 3066276 | c.-85G>A | upstream_gene_variant | 1.0 |
Rv2752c | 3066280 | c.-89C>T | upstream_gene_variant | 1.0 |
ald | 3086742 | c.-78A>C | upstream_gene_variant | 1.0 |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 |
fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
Rv3236c | 3612469 | c.648A>G | synonymous_variant | 0.99 |
Rv3236c | 3612752 | p.Ala122Val | missense_variant | 1.0 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
ethA | 4326135 | p.Pro447Thr | missense_variant | 1.0 |
ethA | 4326363 | p.Gly371Cys | missense_variant | 1.0 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |
gid | 4408048 | p.Cys52Phe | missense_variant | 0.95 |