Run ID: SRR6824678
Sample name:
Date: 04-04-2023 16:56:40
Number of reads: 9600184
Percentage reads mapped: 99.04
Strain: lineage4.2.2
Drug-resistance: RR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.2 | Euro-American | H;T;LAM | None | 0.99 |
lineage4.2.2 | Euro-American (Ural) | T;LAM7-TUR | None | 0.99 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761004 | p.Thr400Ala | missense_variant | 1.0 | rifampicin |
rpoB | 761155 | p.Ser450Leu | missense_variant | 0.99 | rifampicin |
embB | 4247431 | p.Met306Ile | missense_variant | 0.99 | ethambutol |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
mshA | 576077 | c.730C>T | synonymous_variant | 1.0 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
Rv1258c | 1406372 | c.969G>A | synonymous_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.12 |
rrs | 1473055 | n.1210C>T | non_coding_transcript_exon_variant | 0.11 |
rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.11 |
rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.12 |
rrs | 1473097 | n.1252G>A | non_coding_transcript_exon_variant | 0.18 |
rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.18 |
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.17 |
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.17 |
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.17 |
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.17 |
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.17 |
rrs | 1473122 | n.1277T>A | non_coding_transcript_exon_variant | 0.17 |
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.15 |
rrs | 1473147 | n.1302G>A | non_coding_transcript_exon_variant | 0.15 |
rrs | 1473164 | n.1319C>T | non_coding_transcript_exon_variant | 0.14 |
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.14 |
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.17 |
rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 0.16 |
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.16 |
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.16 |
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.17 |
rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.17 |
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.17 |
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.13 |
rrl | 1476295 | n.2638C>G | non_coding_transcript_exon_variant | 0.13 |
rrl | 1476296 | n.2639C>T | non_coding_transcript_exon_variant | 0.13 |
rrl | 1476297 | n.2640C>G | non_coding_transcript_exon_variant | 0.13 |
rrl | 1476298 | n.2641C>G | non_coding_transcript_exon_variant | 0.13 |
rrl | 1476300 | n.2643G>T | non_coding_transcript_exon_variant | 0.13 |
rrl | 1476301 | n.2644A>T | non_coding_transcript_exon_variant | 0.13 |
rrl | 1476309 | n.2652G>C | non_coding_transcript_exon_variant | 0.13 |
rrl | 1476311 | n.2654G>C | non_coding_transcript_exon_variant | 0.13 |
rrl | 1476337 | n.2680C>T | non_coding_transcript_exon_variant | 0.1 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
katG | 2154980 | p.Leu378Met | missense_variant | 1.0 |
katG | 2155819 | p.Tyr98Cys | missense_variant | 1.0 |
PPE35 | 2168121 | p.Leu831His | missense_variant | 1.0 |
PPE35 | 2168805 | p.Gly603Asp | missense_variant | 0.99 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
Rv2752c | 3066280 | c.-89C>T | upstream_gene_variant | 1.0 |
ald | 3086742 | c.-78A>C | upstream_gene_variant | 1.0 |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 |
fbiD | 3339145 | p.Ile10Val | missense_variant | 0.99 |
fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
Rv3236c | 3612469 | c.648A>G | synonymous_variant | 0.99 |
alr | 3841567 | c.-147A>G | upstream_gene_variant | 0.99 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
whiB6 | 4338593 | c.-73delT | upstream_gene_variant | 1.0 |
whiB6 | 4338596 | c.-75G>C | upstream_gene_variant | 1.0 |