TB-Profiler result

Run: ERR4817102
Summary

Run ID: ERR4817102

Sample name:

Date: 01-04-2023 14:48:10

Number of reads: 212234

Percentage reads mapped: 9.68

Strain:

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage1.1.2 Indo-Oceanic EAI3;EAI5 RD239 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6112 p.Met291Ile missense_variant 1.0
gyrB 6124 c.885C>T synonymous_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7792 p.Thr164Met missense_variant 1.0
gyrA 8452 p.Ala384Val missense_variant 1.0
gyrA 9047 c.1746C>T synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9443 c.2142G>A synonymous_variant 1.0
mshA 576000 p.Asp218Ala missense_variant 1.0
rpoB 760070 c.264T>C synonymous_variant 0.25
rpoB 760490 c.684C>T synonymous_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763848 p.Lys160Arg missense_variant 0.18
rpoC 763884 p.Ala172Val missense_variant 1.0
rpoC 763886 c.517C>A synonymous_variant 1.0
rpoC 765171 p.Pro601Leu missense_variant 1.0
rpoC 766197 p.Asp943Gly missense_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776395 p.Phe696Leu missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781700 c.141G>A synonymous_variant 0.4
fbiC 1303013 p.Arg28Leu missense_variant 0.33
embR 1417019 p.Cys110Tyr missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.75
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.88
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.93
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.97
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.94
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.92
rrs 1472210 n.365A>T non_coding_transcript_exon_variant 0.9
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.88
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.88
rrs 1472215 n.370A>T non_coding_transcript_exon_variant 0.84
rrs 1472234 n.389T>A non_coding_transcript_exon_variant 0.67
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.62
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.62
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.62
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.62
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.71
rrs 1472256 n.411T>G non_coding_transcript_exon_variant 0.62
rrs 1472263 n.418C>T non_coding_transcript_exon_variant 0.71
rrs 1472277 n.432C>G non_coding_transcript_exon_variant 0.4
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 1.0
rrs 1472517 n.672T>C non_coding_transcript_exon_variant 1.0
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 1.0
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 1.0
rrs 1472545 n.700A>G non_coding_transcript_exon_variant 1.0
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 1.0
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 1.0
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 1.0
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 1.0
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 1.0
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 1.0
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 1.0
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 1.0
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 1.0
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 1.0
rrs 1472697 n.852T>A non_coding_transcript_exon_variant 1.0
rrs 1472700 n.855C>G non_coding_transcript_exon_variant 1.0
rrs 1472705 n.860G>C non_coding_transcript_exon_variant 1.0
rrs 1472708 n.863T>A non_coding_transcript_exon_variant 1.0
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 1.0
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 1.0
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 1.0
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 1.0
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 1.0
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 1.0
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 1.0
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472928 n.1083A>C non_coding_transcript_exon_variant 1.0
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 1.0
rrs 1473029 n.1184C>G non_coding_transcript_exon_variant 1.0
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 1.0
rrs 1473061 n.1216T>A non_coding_transcript_exon_variant 1.0
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 1.0
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.99
rrs 1473089 n.1244A>C non_coding_transcript_exon_variant 0.98
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.98
rrs 1473094 n.1249T>A non_coding_transcript_exon_variant 0.98
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.98
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.97
rrs 1473115 n.1270G>C non_coding_transcript_exon_variant 0.96
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.96
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.95
rrs 1473127 n.1282G>A non_coding_transcript_exon_variant 0.95
rrs 1473147 n.1302G>C non_coding_transcript_exon_variant 0.93
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.92
rrs 1473150 n.1305T>G non_coding_transcript_exon_variant 0.92
rrs 1473161 n.1316A>C non_coding_transcript_exon_variant 0.91
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.9
rrs 1473164 n.1319C>G non_coding_transcript_exon_variant 0.9
rrs 1473172 n.1327T>C non_coding_transcript_exon_variant 0.92
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.92
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.92
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.95
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.92
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 1.0
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 1.0
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 1.0
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0
rrl 1476252 n.2595T>C non_coding_transcript_exon_variant 0.33
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 1.0
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 1.0
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 1.0
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 1.0
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 1.0
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 1.0
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 1.0
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 1.0
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 1.0
rrl 1476353 n.2696G>A non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.92
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 1.0
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 1.0
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 1.0
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 1.0
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2167983 p.Gly877Asp missense_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
pncA 2290109 c.-868C>T upstream_gene_variant 0.4
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2519183 c.1070dupT frameshift_variant 0.25
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
ahpC 2726150 c.-43G>A upstream_gene_variant 0.33
folC 2747156 p.Ala148Val missense_variant 0.25
Rv2752c 3064632 c.1560C>T synonymous_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474597 c.591C>A synonymous_variant 1.0
fprA 3474787 p.Arg261Cys missense_variant 0.22
fprA 3475159 p.Asn385Asp missense_variant 1.0
fbiB 3641678 c.144T>C synonymous_variant 0.5
rpoA 3877545 c.963G>A synonymous_variant 0.33
rpoA 3877554 c.954G>T synonymous_variant 1.0
ddn 3987057 p.Arg72Trp missense_variant 1.0
clpC1 4040517 p.Val63Ala missense_variant 1.0
embC 4240074 p.Glu71Gly missense_variant 0.15
embC 4240535 p.Ser225Arg missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4241042 p.Asn394Asp missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243848 p.Val206Met missense_variant 1.0
embA 4245969 p.Pro913Ser missense_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4248571 c.2058G>T synonymous_variant 0.22
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407873 c.330G>T synonymous_variant 1.0