TB-Profiler result

Run: ERR4818444
Summary

Run ID: ERR4818444

Sample name:

Date: 01-04-2023 15:33:34

Number of reads: 1837961

Percentage reads mapped: 86.49

Strain: lineage4.6.5

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.5 Euro-American T;LAM None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
tlyA 1918647 p.Asn236Lys missense_variant 1.0 capreomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5489 p.Ile84Val missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490756 c.-27T>G upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777974 c.507C>T synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.71
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.92
rrs 1472223 n.378C>G non_coding_transcript_exon_variant 1.0
rrs 1472228 n.383G>C non_coding_transcript_exon_variant 1.0
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 1.0
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 1.0
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 1.0
rrs 1472266 n.421C>A non_coding_transcript_exon_variant 1.0
rrs 1472277 n.432C>G non_coding_transcript_exon_variant 1.0
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.75
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.75
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 1.0
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 1.0
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 1.0
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.9
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.9
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.9
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.92
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.79
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.75
rrs 1472812 n.967A>C non_coding_transcript_exon_variant 0.75
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.5
rrl 1475499 n.1842C>G non_coding_transcript_exon_variant 0.86
rrl 1475516 n.1859T>A non_coding_transcript_exon_variant 0.88
rrl 1475518 n.1861A>T non_coding_transcript_exon_variant 0.88
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 0.88
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.88
rrl 1475540 n.1883C>T non_coding_transcript_exon_variant 0.88
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.88
rrl 1475549 n.1892T>G non_coding_transcript_exon_variant 0.88
rrl 1475553 n.1896G>C non_coding_transcript_exon_variant 0.88
rrl 1475555 n.1898T>G non_coding_transcript_exon_variant 0.88
rrl 1475570 n.1913A>T non_coding_transcript_exon_variant 0.88
rrl 1475571 n.1914A>C non_coding_transcript_exon_variant 0.88
rrl 1475576 n.1919C>T non_coding_transcript_exon_variant 0.88
rrl 1475591 n.1934G>T non_coding_transcript_exon_variant 0.86
rrl 1476336 n.2679C>G non_coding_transcript_exon_variant 1.0
rrl 1476356 n.2699C>G non_coding_transcript_exon_variant 1.0
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.95
rrl 1476384 n.2727G>C non_coding_transcript_exon_variant 0.95
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.96
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.96
rrl 1476443 n.2786G>C non_coding_transcript_exon_variant 0.69
rrl 1476455 n.2798C>G non_coding_transcript_exon_variant 0.67
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.6
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.6
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.64
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.57
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.45
inhA 1674678 c.477C>T synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746995 p.Val202Ile missense_variant 1.0
ribD 2987369 c.531G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3640346 c.-196delA upstream_gene_variant 1.0
clpC1 4038332 c.2373C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249422 p.Asp970Ala missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0