TB-Profiler result

Run: ERR9786705
Summary

Run ID: ERR9786705

Sample name:

Date: 02-04-2023 12:40:38

Number of reads: 822004

Percentage reads mapped: 74.27

Strain: lineage4.1.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 763528 c.159G>C synonymous_variant 0.1
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781510 c.-50G>A upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.12
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.11
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.11
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.12
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.11
rrs 1472579 n.734G>A non_coding_transcript_exon_variant 0.12
rrs 1472581 n.736A>G non_coding_transcript_exon_variant 0.12
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.14
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.16
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.13
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.16
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.16
rrs 1473026 n.1181T>C non_coding_transcript_exon_variant 0.12
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.14
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.12
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.11
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.11
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.11
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.12
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.12
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.11
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.12
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.13
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 0.14
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.14
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.13
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.13
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.14
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.14
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.14
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.14
rrl 1473922 n.265A>T non_coding_transcript_exon_variant 0.14
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.14
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.12
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.15
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.13
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.14
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.14
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.14
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.1
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.1
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.12
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.13
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.13
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.13
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.11
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.11
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.12
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.12
rrl 1475892 n.2235A>G non_coding_transcript_exon_variant 0.14
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.14
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.13
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.14
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.14
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.2
rrl 1476025 n.2368G>A non_coding_transcript_exon_variant 0.14
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.14
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.11
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.11
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.11
rrl 1476043 n.2387_2388delTG non_coding_transcript_exon_variant 0.11
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.11
rrl 1476048 n.2391G>C non_coding_transcript_exon_variant 0.11
rrl 1476050 n.2394_2395insTG non_coding_transcript_exon_variant 0.11
rrl 1476058 n.2401T>C non_coding_transcript_exon_variant 0.16
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.18
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.17
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.17
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.12
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.12
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.16
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.23
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.12
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.15
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.15
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.15
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.13
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.15
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.14
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.11
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.11
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.1
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.13
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.1
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.16
rrl 1476420 n.2763G>A non_coding_transcript_exon_variant 0.15
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.15
rrl 1476433 n.2776C>T non_coding_transcript_exon_variant 0.16
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.15
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.15
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.16
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.15
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.14
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.12
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.12
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.12
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.12
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.12
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.16
rrl 1476528 n.2871A>T non_coding_transcript_exon_variant 0.11
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.11
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.11
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.11
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.12
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.13
rpsA 1834399 p.His286Gln missense_variant 0.13
rpsA 1834405 c.864C>T synonymous_variant 0.13
rpsA 1834408 c.867C>T synonymous_variant 0.13
rpsA 1834417 c.876G>C synonymous_variant 0.14
rpsA 1834423 c.882G>C synonymous_variant 0.14
rpsA 1834435 c.894G>C synonymous_variant 0.12
rpsA 1834438 c.897C>T synonymous_variant 0.12
rpsA 1834451 c.910T>C synonymous_variant 0.15
rpsA 1834459 c.918G>C synonymous_variant 0.17
rpsA 1834468 c.927A>G synonymous_variant 0.2
rpsA 1834480 c.939C>G synonymous_variant 0.2
rpsA 1834519 c.978G>C synonymous_variant 0.11
rpsA 1834528 c.987T>G synonymous_variant 0.11
rpsA 1834531 c.990C>T synonymous_variant 0.11
rpsA 1834543 c.1002C>G synonymous_variant 0.1
rpsA 1834552 c.1011G>C synonymous_variant 0.1
rpsA 1834555 c.1014T>G synonymous_variant 0.1
rpsA 1834633 c.1092A>G synonymous_variant 0.1
rpsA 1834639 c.1098T>C synonymous_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4039246 p.Val487Leu missense_variant 0.95
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0