TB-Profiler result

Run: SRR13861275
Summary

Run ID: SRR13861275

Sample name:

Date: 03-04-2023 09:27:51

Number of reads: 763008

Percentage reads mapped: 12.73

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 9490 p.Gly730Asp missense_variant 1.0
fgd1 491231 p.Phe150Tyr missense_variant 1.0
rpoB 761222 c.1416G>C synonymous_variant 0.12
rpoC 762989 c.-381G>C upstream_gene_variant 0.16
rpoC 762995 c.-375G>T upstream_gene_variant 0.12
rpoC 766128 p.Ala920Gly missense_variant 1.0
rpsL 781503 c.-57T>C upstream_gene_variant 1.0
fbiC 1303099 c.170dupA frameshift_variant 1.0
fbiC 1304043 c.1116delC frameshift_variant 1.0
Rv1258c 1406861 p.Ile160Met missense_variant 1.0
Rv1258c 1407463 c.-123G>C upstream_gene_variant 1.0
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.18
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.18
rrs 1472108 n.263C>A non_coding_transcript_exon_variant 0.18
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.23
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 0.19
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.19
rrs 1472133 n.288G>A non_coding_transcript_exon_variant 0.19
rrs 1472135 n.290C>T non_coding_transcript_exon_variant 0.19
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.19
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.17
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.17
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.17
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 0.19
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.19
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.17
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.16
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.15
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.16
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.17
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.16
rrs 1472303 n.458G>A non_coding_transcript_exon_variant 1.0
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.37
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.39
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.39
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.38
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.38
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.39
rrs 1472971 n.1126G>C non_coding_transcript_exon_variant 0.37
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.36
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.34
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.36
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.37
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.37
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.37
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.37
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.35
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.34
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.43
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.31
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.31
rrl 1474235 n.578G>T non_coding_transcript_exon_variant 1.0
rrl 1475139 n.1482C>T non_coding_transcript_exon_variant 1.0
rrl 1476248 n.2591G>A non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.68
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.74
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.73
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.74
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.74
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.79
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.78
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.78
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.79
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.79
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.79
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.78
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.78
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.79
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.78
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.79
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.78
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.78
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.79
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.79
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.53
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.18
rrl 1476576 n.2919C>G non_coding_transcript_exon_variant 1.0
kasA 2518209 p.Thr32Arg missense_variant 1.0
folC 2746788 p.Ala271Pro missense_variant 1.0
thyX 3067214 p.Ser244Arg missense_variant 1.0
fbiD 3339396 c.279C>T synonymous_variant 1.0
rpoA 3878048 p.Ala154Ser missense_variant 1.0
embB 4248368 p.Leu619Val missense_variant 1.0
ethA 4327082 p.Cys131Ser missense_variant 1.0
ethA 4327097 p.Leu126His missense_variant 1.0
gid 4407792 c.411G>C synonymous_variant 1.0