TB-Profiler result

Run: SRR13861484
Summary

Run ID: SRR13861484

Sample name:

Date: 03-04-2023 09:32:59

Number of reads: 236310

Percentage reads mapped: 4.73

Strain: lineage4.9

Drug-resistance: RR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761131 p.Gly442Glu missense_variant 0.36 rifampicin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6655 c.-647T>C upstream_gene_variant 0.38
gyrA 6670 c.-632G>C upstream_gene_variant 0.25
gyrA 6673 c.-629A>C upstream_gene_variant 0.25
gyrA 6700 c.-602T>C upstream_gene_variant 0.25
gyrA 6703 c.-599G>C upstream_gene_variant 0.25
gyrA 6706 c.-596G>A upstream_gene_variant 0.25
gyrA 6709 c.-593A>G upstream_gene_variant 0.25
gyrA 6712 c.-590G>C upstream_gene_variant 0.25
gyrA 6727 c.-575G>T upstream_gene_variant 0.25
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.25
gyrA 6745 c.-557T>G upstream_gene_variant 0.25
gyrA 7427 c.126G>C synonymous_variant 0.29
gyrA 7442 c.141G>C synonymous_variant 0.29
gyrA 7451 c.150C>G synonymous_variant 0.25
gyrA 7457 c.156T>C synonymous_variant 0.29
gyrA 7466 c.165G>A synonymous_variant 0.22
gyrA 7469 c.168C>T synonymous_variant 0.2
gyrA 7472 c.171T>C synonymous_variant 0.2
gyrA 7475 c.174A>C synonymous_variant 0.2
gyrA 7480 p.Phe60Tyr missense_variant 0.2
gyrA 7484 c.183T>C synonymous_variant 0.25
gyrA 7487 c.186C>G synonymous_variant 0.25
gyrA 7490 c.189C>T synonymous_variant 0.25
gyrA 7523 c.222C>G synonymous_variant 0.29
gyrA 7532 c.231T>C synonymous_variant 0.25
gyrA 7541 c.240C>G synonymous_variant 0.25
fgd1 490955 p.Met58Arg missense_variant 1.0
rpoB 760181 c.375T>C synonymous_variant 0.25
rpoB 760184 c.378A>G synonymous_variant 0.22
rpoB 760196 c.390C>G synonymous_variant 0.27
rpoB 760223 c.417T>C synonymous_variant 0.25
rpoB 760235 c.429T>C synonymous_variant 0.33
rpoB 760283 c.477G>C synonymous_variant 0.33
rpoB 760307 c.501T>C synonymous_variant 0.36
rpoB 760328 c.522G>C synonymous_variant 0.3
rpoB 760331 c.525G>C synonymous_variant 0.33
rpoB 760337 c.531C>G synonymous_variant 0.33
rpoB 760340 c.534G>C synonymous_variant 0.25
rpoB 760361 c.555T>C synonymous_variant 0.33
rpoB 760376 p.Asp190Glu missense_variant 0.4
rpoB 760406 c.600G>C synonymous_variant 0.4
rpoB 760418 c.612G>C synonymous_variant 0.4
rpoB 760424 c.618C>G synonymous_variant 0.38
rpoB 760430 c.624T>C synonymous_variant 0.38
rpoB 760475 c.669A>G synonymous_variant 0.33
rpoB 760481 c.675G>C synonymous_variant 0.33
rpoB 760484 c.678A>G synonymous_variant 0.33
rpoB 761102 c.1296A>G synonymous_variant 0.17
rpoB 761126 c.1320G>T synonymous_variant 0.33
rpoB 761129 c.1323G>C synonymous_variant 0.36
rpoB 761133 p.Leu443Ile missense_variant 0.38
rpoB 761150 c.1344A>C synonymous_variant 0.47
rpoB 761151 p.Leu449Val missense_variant 0.33
rpoB 761156 c.1350G>C synonymous_variant 0.36
rpoB 761162 c.1356G>C synonymous_variant 0.33
rpoB 761165 c.1359G>C synonymous_variant 0.47
rpoB 761168 c.1362C>G synonymous_variant 0.47
rpoB 761178 p.Ser458Thr missense_variant 0.42
rpoB 761183 c.1377T>G synonymous_variant 0.17
rpoB 761189 c.1383T>G synonymous_variant 0.17
rpoB 761192 c.1386C>G synonymous_variant 0.42
rpoB 761195 c.1389G>C synonymous_variant 0.38
rpoB 761196 p.Leu464Phe missense_variant 0.36
rpoB 761204 c.1398C>T synonymous_variant 0.36
rpoB 761207 c.1401C>T synonymous_variant 0.36
rpoB 761213 c.1407G>A synonymous_variant 0.42
rpoB 761220 p.Ser472Thr missense_variant 0.42
rpoB 761234 c.1428G>C synonymous_variant 0.38
rpoB 761235 p.Met477Val missense_variant 0.38
rpoB 761249 c.1443A>G synonymous_variant 0.15
rpoB 761255 c.1449T>G synonymous_variant 0.25
rpoB 761261 c.1455G>T synonymous_variant 0.25
rpoB 761327 c.1521A>G synonymous_variant 0.29
rpoB 761360 c.1554T>C synonymous_variant 0.33
rpoB 761362 p.Ser519Thr missense_variant 0.33
rpoB 761373 p.Val523His missense_variant 0.33
rpoB 761414 c.1608A>G synonymous_variant 0.25
rpoB 761423 c.1617T>C synonymous_variant 0.29
rpoB 761579 c.1773G>C synonymous_variant 0.25
rpoB 761606 c.1800C>G synonymous_variant 0.29
rpoC 762860 c.-510G>C upstream_gene_variant 0.3
rpoC 762863 c.-507T>C upstream_gene_variant 0.3
rpoB 762878 p.Ile1024Met missense_variant 0.38
rpoB 762879 p.Met1025Leu missense_variant 0.38
rpoB 762888 p.His1028Asn missense_variant 0.42
rpoB 762911 p.Ile1035Met missense_variant 0.45
rpoC 762920 c.-450C>T upstream_gene_variant 0.45
rpoC 762929 c.-441G>C upstream_gene_variant 0.46
rpoB 762930 p.Pro1042Ser missense_variant 0.38
rpoC 762936 c.-434_-432delTCGinsAGC upstream_gene_variant 0.36
rpoB 762939 p.Met1045Leu missense_variant 0.36
rpoB 762942 p.Ile1046Val missense_variant 0.36
rpoC 762962 c.-408C>T upstream_gene_variant 0.42
rpoC 762971 c.-399G>A upstream_gene_variant 0.42
rpoC 762983 c.-387C>T upstream_gene_variant 0.42
rpoC 762989 c.-381G>C upstream_gene_variant 0.55
rpoC 762995 c.-375G>T upstream_gene_variant 0.5
rpoC 763115 c.-255T>C upstream_gene_variant 0.18
rpoC 763136 c.-234C>T upstream_gene_variant 0.17
rpoC 763148 c.-222G>C upstream_gene_variant 0.18
rpoC 763158 c.-212C>T upstream_gene_variant 0.2
rpoC 763166 c.-204A>G upstream_gene_variant 0.2
rpoC 763169 c.-201A>G upstream_gene_variant 0.2
rpoC 763202 c.-168A>C upstream_gene_variant 0.2
rpoC 763205 c.-165G>C upstream_gene_variant 0.2
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.2
rpoC 763214 c.-156T>C upstream_gene_variant 0.2
rpoC 763220 c.-150G>C upstream_gene_variant 0.22
rpoC 763226 c.-144A>G upstream_gene_variant 0.25
rpoC 763238 c.-132T>C upstream_gene_variant 0.22
rpoC 763996 c.627T>C synonymous_variant 0.17
rpoC 764005 c.636G>C synonymous_variant 0.17
rpoC 764011 c.642T>C synonymous_variant 0.17
rpoC 764024 c.655T>C synonymous_variant 0.17
rpoC 764040 p.Ser224Asn missense_variant 0.21
rpoC 764044 c.675T>C synonymous_variant 0.21
rpoC 764059 c.690G>C synonymous_variant 0.15
rpoC 764083 c.714A>G synonymous_variant 0.15
rpoC 764098 c.729A>G synonymous_variant 0.25
rpoC 764101 c.732C>G synonymous_variant 0.25
rpoC 764131 c.762T>C synonymous_variant 0.2
rpoC 764161 c.792G>C synonymous_variant 0.2
rpoC 764387 c.1018T>C synonymous_variant 0.3
rpoC 764401 c.1032C>T synonymous_variant 0.5
rpoC 764404 c.1035C>T synonymous_variant 0.5
rpoC 764405 c.1036A>C synonymous_variant 0.5
rpoC 764419 c.1050C>T synonymous_variant 0.55
rpoC 764428 c.1059G>T synonymous_variant 0.5
rpoC 764434 c.1065A>G synonymous_variant 0.55
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.55
rpoC 764441 p.Ile358Leu missense_variant 0.5
rpoC 764446 c.1077T>C synonymous_variant 0.5
rpoC 764451 p.Gly361Ala missense_variant 0.5
rpoC 764455 c.1086G>T synonymous_variant 0.5
rpoC 764461 p.Glu364Asp missense_variant 0.5
rpoC 764470 c.1101C>G synonymous_variant 0.5
rpoC 764471 p.Asn368Arg missense_variant 0.5
rpoC 764479 c.1110G>A synonymous_variant 0.6
rpoC 764485 c.1116G>C synonymous_variant 0.6
rpoC 764498 p.Ser377Ala missense_variant 0.6
rpoC 764503 c.1134G>C synonymous_variant 0.6
rpoC 764509 c.1140G>C synonymous_variant 0.6
rpoC 764513 p.Phe382Leu missense_variant 0.6
rpoC 764521 c.1152T>C synonymous_variant 0.6
rpoC 764527 c.1158C>T synonymous_variant 0.43
rpoC 766738 c.3369G>T synonymous_variant 0.18
rpoC 766750 c.3381C>G synonymous_variant 0.2
rpoC 766765 c.3396A>C synonymous_variant 0.17
rpoC 766774 c.3405T>C synonymous_variant 0.17
rpoC 766945 c.3576A>G synonymous_variant 0.15
rpoC 766978 c.3609C>G synonymous_variant 0.15
rpoC 766996 c.3627C>T synonymous_variant 0.17
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.17
rpoC 767014 c.3645G>C synonymous_variant 0.17
mmpL5 775883 p.Ile866Leu missense_variant 0.2
mmpL5 775898 c.2583G>A synonymous_variant 0.2
mmpL5 775901 c.2580G>A synonymous_variant 0.2
mmpL5 775904 c.2577G>A synonymous_variant 0.2
mmpL5 775909 p.Leu858Phe missense_variant 0.22
mmpL5 775912 c.2569C>A synonymous_variant 0.2
mmpL5 775916 c.2565T>G synonymous_variant 0.22
mmpL5 775937 c.2544G>C synonymous_variant 0.2
mmpL5 775966 p.Ala839Ser missense_variant 0.29
mmpL5 775970 c.2511G>C synonymous_variant 0.25
mmpL5 775975 c.2506T>C synonymous_variant 0.22
mmpL5 775981 p.Leu834Met missense_variant 0.33
mmpL5 775991 c.2490G>A synonymous_variant 0.2
mmpL5 775997 c.2484T>C synonymous_variant 0.22
mmpL5 776000 p.Leu827Ile missense_variant 0.3
mmpL5 776005 p.Ile826Leu missense_variant 0.27
mmpL5 776009 c.2472A>G synonymous_variant 0.36
mmpL5 776066 c.2415C>G synonymous_variant 0.18
mmpL5 776078 c.2403C>G synonymous_variant 0.18
mmpL5 776087 c.2394C>G synonymous_variant 0.22
mmpL5 776100 p.Thr794Ile missense_variant 0.22
mmpS5 779639 c.-735dupG upstream_gene_variant 1.0
rpsL 781832 c.273T>C synonymous_variant 0.15
rpsL 781841 c.282C>G synonymous_variant 0.15
rpsL 781868 c.309T>C synonymous_variant 0.18
rpsL 781871 c.312G>C synonymous_variant 0.17
rpsL 781892 c.333A>G synonymous_variant 0.23
rpsL 781898 c.339A>T synonymous_variant 0.21
rpsL 781916 c.357T>C synonymous_variant 0.15
rpsL 781929 p.Gly124Ser missense_variant 0.17
rplC 800612 c.-197A>G upstream_gene_variant 0.43
rplC 800618 c.-191T>C upstream_gene_variant 0.38
rplC 800648 c.-161A>C upstream_gene_variant 0.38
rplC 800654 c.-155T>C upstream_gene_variant 0.38
rplC 800693 c.-116A>G upstream_gene_variant 0.38
fbiC 1304499 c.1569T>G synonymous_variant 0.17
fbiC 1304517 c.1587C>T synonymous_variant 0.22
fbiC 1304520 c.1590A>C synonymous_variant 0.22
fbiC 1304523 c.1593G>T synonymous_variant 0.22
fbiC 1304526 c.1596T>G synonymous_variant 0.22
fbiC 1304529 c.1599T>C synonymous_variant 0.78
fbiC 1304544 c.1614T>C synonymous_variant 0.29
fbiC 1304545 p.Val539Thr missense_variant 0.33
fbiC 1304559 p.Glu543Asp missense_variant 0.5
fbiC 1304565 c.1635C>G synonymous_variant 0.33
fbiC 1304568 c.1638T>C synonymous_variant 0.33
fbiC 1304574 c.1644C>G synonymous_variant 0.33
fbiC 1304580 c.1650T>C synonymous_variant 0.25
fbiC 1304628 c.1698G>C synonymous_variant 0.22
fbiC 1304634 c.1704C>G synonymous_variant 0.25
fbiC 1304640 c.1710A>C synonymous_variant 0.25
Rv1258c 1406845 p.Ala166Pro missense_variant 1.0
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.33
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.3
rrs 1472108 n.263C>A non_coding_transcript_exon_variant 0.4
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.4
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 0.4
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.4
rrs 1472133 n.288G>A non_coding_transcript_exon_variant 0.4
rrs 1472135 n.290C>T non_coding_transcript_exon_variant 0.4
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.4
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.36
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.36
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.27
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 0.4
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.5
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.5
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.5
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.45
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.42
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.45
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.4
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.18
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.2
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.22
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.6
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.57
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.57
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.57
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.55
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.57
rrs 1472971 n.1126G>C non_coding_transcript_exon_variant 0.57
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.55
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.55
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.55
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.5
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.55
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.55
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.55
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.52
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.52
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.62
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.33
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.33
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.25
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.25
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.5
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.5
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.38
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.33
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.33
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.4
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.4
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.25
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.25
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.91
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.92
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.94
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.94
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.93
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.95
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.94
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.94
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.94
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.94
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.95
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.94
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.95
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.95
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.94
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.94
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.93
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.93
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.93
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.91
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.68
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.38
inhA 1674480 c.279T>C synonymous_variant 0.5
inhA 1674486 c.285T>C synonymous_variant 0.5
inhA 1674489 c.288G>C synonymous_variant 0.5
inhA 1674498 c.297G>A synonymous_variant 0.5
inhA 1674507 c.306G>C synonymous_variant 0.5
inhA 1674537 c.336C>G synonymous_variant 0.5
inhA 1674542 p.Ala114Glu missense_variant 0.5
inhA 1674549 c.348G>C synonymous_variant 0.5
inhA 1674555 c.354G>A synonymous_variant 0.5
inhA 1674561 c.360C>T synonymous_variant 0.5
inhA 1674564 c.363C>T synonymous_variant 0.5
inhA 1674582 c.381T>C synonymous_variant 0.33
inhA 1674585 c.384T>C synonymous_variant 0.33
inhA 1674589 p.Met130Leu missense_variant 0.4
inhA 1674607 p.Pro136Ser missense_variant 0.57
inhA 1674624 c.423A>C synonymous_variant 0.29
inhA 1674627 c.426T>G synonymous_variant 0.29
inhA 1674630 c.429C>G synonymous_variant 0.29
inhA 1674636 c.435C>G synonymous_variant 0.29
inhA 1674654 c.453G>C synonymous_variant 0.25
inhA 1674778 p.Pro193Ala missense_variant 0.86
rpsA 1833838 c.297G>C synonymous_variant 0.29
rpsA 1833841 c.300C>G synonymous_variant 0.29
rpsA 1833847 c.306C>G synonymous_variant 0.29
rpsA 1833856 c.315A>G synonymous_variant 0.29
rpsA 1833862 c.321G>T synonymous_variant 0.29
rpsA 1833874 c.333T>C synonymous_variant 0.25
rpsA 1833970 c.429G>C synonymous_variant 0.3
rpsA 1833979 c.438T>C synonymous_variant 0.36
rpsA 1834000 c.459G>C synonymous_variant 0.33
rpsA 1834015 c.474G>C synonymous_variant 0.44
rpsA 1834021 c.480C>T synonymous_variant 0.44
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.33
rpsA 1834102 c.561T>C synonymous_variant 0.33
rpsA 1834150 c.609G>C synonymous_variant 0.25
rpsA 1834153 c.612T>C synonymous_variant 0.25
rpsA 1834154 p.Asn205Gln missense_variant 0.25
rpsA 1834157 c.616T>C synonymous_variant 0.25
rpsA 1834162 c.621A>G synonymous_variant 0.25
rpsA 1834165 c.624A>G synonymous_variant 0.22
rpsA 1834169 p.Thr210Ala missense_variant 0.22
rpsA 1834177 c.636A>C synonymous_variant 0.33
rpsA 1834186 c.645C>G synonymous_variant 0.38
rpsA 1834189 c.648G>C synonymous_variant 0.33
rpsA 1834195 c.654G>C synonymous_variant 0.33
rpsA 1834222 c.681T>C synonymous_variant 0.33
rpsA 1834225 c.684C>G synonymous_variant 0.33
rpsA 1834240 c.699T>C synonymous_variant 0.33
rpsA 1834249 c.708T>C synonymous_variant 0.25
rpsA 1834348 c.807T>C synonymous_variant 0.29
rpsA 1834366 c.825A>G synonymous_variant 0.25
rpsA 1834375 c.834G>A synonymous_variant 0.25
rpsA 1834396 c.855G>C synonymous_variant 0.29
rpsA 1834411 c.870T>C synonymous_variant 0.22
rpsA 1834417 c.876G>C synonymous_variant 0.22
rpsA 1834423 c.882G>C synonymous_variant 0.22
rpsA 1834435 c.894G>C synonymous_variant 0.25
rpsA 1834451 c.910T>C synonymous_variant 0.2
rpsA 1834465 c.924T>C synonymous_variant 0.18
rpsA 1834468 c.927A>G synonymous_variant 0.18
rpsA 1834474 c.933C>G synonymous_variant 0.25
PPE35 2169081 p.Leu511Ser missense_variant 1.0
PPE35 2169202 p.Ser471Pro missense_variant 1.0
Rv1979c 2222091 c.1074G>T synonymous_variant 1.0
Rv1979c 2223306 c.-142T>A upstream_gene_variant 1.0
pncA 2289228 p.Ile5Asn missense_variant 1.0
kasA 2518176 p.Ala21Gly missense_variant 1.0
eis 2714755 p.Pro193Gln missense_variant 1.0
ahpC 2726324 c.132A>G synonymous_variant 1.0
ahpC 2726362 p.Phe57Ser missense_variant 1.0
pepQ 2859580 p.Leu280Arg missense_variant 1.0
pepQ 2859999 c.420G>T synonymous_variant 1.0
Rv2752c 3065553 c.639A>C synonymous_variant 0.33
Rv2752c 3065556 c.636G>C synonymous_variant 0.4
Rv2752c 3065562 c.630T>C synonymous_variant 0.4
Rv2752c 3065568 p.Ile208Leu missense_variant 0.4
Rv2752c 3065580 c.612G>C synonymous_variant 0.29
Rv2752c 3065586 c.606C>T synonymous_variant 0.33
Rv2752c 3065595 p.Leu199Phe missense_variant 0.29
Rv2752c 3065604 c.588G>C synonymous_variant 0.29
Rv2752c 3065607 c.585C>G synonymous_variant 0.29
Rv2752c 3065612 p.Thr194Ala missense_variant 0.29
Rv2752c 3065616 c.576C>T synonymous_variant 0.25
Rv2752c 3065634 c.558G>C synonymous_variant 0.25
Rv2752c 3065637 c.555A>G synonymous_variant 0.22
Rv2752c 3065649 c.543T>G synonymous_variant 0.22
Rv2752c 3065901 c.291A>G synonymous_variant 0.29
Rv2752c 3065916 p.Phe92Tyr missense_variant 0.29
Rv2752c 3065919 c.273G>C synonymous_variant 0.29
Rv2752c 3065925 p.Ala89Gly missense_variant 0.25
Rv2752c 3065928 c.264G>C synonymous_variant 0.25
Rv2752c 3065947 p.Gly82Ala missense_variant 0.18
Rv2752c 3065952 c.240C>T synonymous_variant 0.2
Rv2752c 3065955 c.235_237delTTGinsCTC synonymous_variant 0.22
Rv2752c 3065979 c.213T>C synonymous_variant 0.25
Rv2752c 3065993 p.Val67Ile missense_variant 0.27
Rv2752c 3065994 c.198T>C synonymous_variant 0.25
Rv2752c 3065997 c.195C>G synonymous_variant 0.25
Rv2752c 3066002 p.Met64Leu missense_variant 0.25
Rv2752c 3066024 c.168T>C synonymous_variant 0.23
Rv2752c 3066040 p.Gly51Ala missense_variant 0.17
thyX 3067577 p.Glu123Asp missense_variant 0.5
thyX 3067582 p.Met122Leu missense_variant 0.5
thyX 3067586 c.360C>G synonymous_variant 0.5
thyX 3067601 c.345G>C synonymous_variant 0.4
thyX 3067604 c.342G>C synonymous_variant 0.4
thyX 3067610 p.Lys112Asn missense_variant 0.5
thyX 3067613 c.333G>A synonymous_variant 0.5
thyX 3067619 c.327A>C synonymous_variant 0.5
thyX 3067640 c.306G>C synonymous_variant 0.4
thyX 3067643 c.303C>T synonymous_variant 0.4
thyX 3067652 c.294T>C synonymous_variant 0.4
thyX 3067694 c.252G>C synonymous_variant 0.4
thyX 3067718 c.228C>G synonymous_variant 0.33
thyX 3067721 c.225T>C synonymous_variant 0.33
thyX 3067724 c.222G>A synonymous_variant 0.33
thyX 3067727 c.219A>C synonymous_variant 0.33
thyX 3067739 c.207T>C synonymous_variant 0.43
thyX 3067742 c.204A>C synonymous_variant 0.38
thyX 3067761 p.Arg62Lys missense_variant 0.43
thyX 3067765 p.Leu61Ile missense_variant 0.43
thyX 3067781 c.165C>G synonymous_variant 0.43
thyX 3067787 c.159G>A synonymous_variant 0.43
thyX 3067793 c.153T>C synonymous_variant 0.38
thyX 3067799 c.147G>A synonymous_variant 0.38
thyX 3067802 c.144C>G synonymous_variant 0.38
thyX 3067814 c.132T>C synonymous_variant 0.33
thyX 3067826 c.120C>G synonymous_variant 0.33
thyX 3067850 c.96A>C synonymous_variant 0.18
thyX 3067940 c.6C>G synonymous_variant 1.0
thyA 3073953 c.519T>C synonymous_variant 0.5
thyA 3073977 c.495A>G synonymous_variant 0.5
thyA 3073989 c.483T>C synonymous_variant 0.4
thyA 3074001 c.471C>G synonymous_variant 0.5
thyA 3074004 c.468T>C synonymous_variant 0.5
thyA 3074010 c.462C>G synonymous_variant 0.5
thyA 3074031 c.441T>C synonymous_variant 0.29
thyA 3074037 c.435C>G synonymous_variant 0.38
thyA 3074056 p.Glu139Pro missense_variant 0.33
thyA 3074061 c.411A>G synonymous_variant 0.33
thyA 3074076 c.396C>G synonymous_variant 0.33
thyA 3074097 c.375C>G synonymous_variant 0.33
thyA 3074100 c.372T>C synonymous_variant 0.33
thyA 3074106 c.366T>C synonymous_variant 0.25
thyA 3074620 c.-149C>A upstream_gene_variant 1.0
fprA 3473809 c.-198G>C upstream_gene_variant 0.29
fprA 3473812 c.-195G>A upstream_gene_variant 0.29
fprA 3473836 c.-171C>A upstream_gene_variant 0.25
fprA 3473861 c.-146T>G upstream_gene_variant 0.88
fprA 3474953 p.Gln316Arg missense_variant 1.0
ddn 3986889 p.Phe16Val missense_variant 1.0
clpC1 4038965 c.1740T>C synonymous_variant 0.22
clpC1 4038971 c.1734T>C synonymous_variant 0.25
clpC1 4038974 c.1731T>C synonymous_variant 0.25
clpC1 4039448 c.1257A>G synonymous_variant 0.33
clpC1 4039454 c.1251A>G synonymous_variant 0.33
clpC1 4039979 c.726C>G synonymous_variant 0.29
clpC1 4039996 p.Glu237Gln missense_variant 0.25
embC 4240831 c.969T>G synonymous_variant 0.18
embC 4240885 c.1023T>C synonymous_variant 0.25
embC 4240897 c.1035C>G synonymous_variant 0.33
embC 4240900 c.1038A>G synonymous_variant 0.22
embC 4240919 c.1057_1059delCTCinsTTG synonymous_variant 0.25
embC 4240936 c.1074A>G synonymous_variant 0.25
embC 4240945 c.1083T>C synonymous_variant 0.22
embC 4240951 c.1089C>G synonymous_variant 0.25
embC 4240954 p.Ile364Met missense_variant 0.29
embC 4240957 c.1095C>G synonymous_variant 0.29
embC 4240966 c.1104G>T synonymous_variant 0.29
embC 4241023 c.1161T>G synonymous_variant 0.4
embC 4241026 c.1164C>G synonymous_variant 0.4
embC 4241104 c.1242G>A synonymous_variant 0.5
embC 4241107 c.1245G>C synonymous_variant 0.5
embC 4241137 c.1275G>C synonymous_variant 0.5
embC 4241140 c.1278A>G synonymous_variant 0.5
embC 4241141 p.Ile427Val missense_variant 0.5
embC 4241158 c.1296T>C synonymous_variant 0.5
embC 4241161 c.1299C>G synonymous_variant 0.5
embC 4241162 c.1300T>C synonymous_variant 0.5
embC 4242041 p.Met727Leu missense_variant 1.0
embA 4244228 c.996A>G synonymous_variant 0.22
embA 4244233 p.Ala334Gly missense_variant 0.22
embA 4244247 p.Val339Ile missense_variant 0.22
embA 4244254 p.Arg341His missense_variant 0.22
embA 4244257 p.Phe342Trp missense_variant 0.2
embA 4244267 c.1035G>C synonymous_variant 0.22
embA 4244276 c.1044A>C synonymous_variant 0.22
embA 4244284 p.Pro351Arg missense_variant 0.2
embA 4244298 p.Ser356Ala missense_variant 0.17
embA 4244309 c.1077C>G synonymous_variant 0.2
embA 4244312 c.1080T>G synonymous_variant 0.22
embA 4244315 c.1083G>C synonymous_variant 0.22
embA 4244324 c.1092T>G synonymous_variant 0.25
embA 4244327 c.1095T>C synonymous_variant 0.25
embA 4244337 p.Leu369Val missense_variant 0.29
embA 4244340 p.Ser370Ala missense_variant 0.25
embA 4244723 p.Gln497His missense_variant 1.0
embA 4245137 c.1905T>C synonymous_variant 0.4
embA 4245149 c.1917C>G synonymous_variant 0.5
embA 4245182 c.1950T>C synonymous_variant 0.4
aftB 4267979 c.858G>C synonymous_variant 1.0
ethR 4327804 p.Ala86Thr missense_variant 0.5