Run ID: SRR23961529
Sample name:
Date: 2024-03-26T20:01:16.023951
Number of reads: 209237
Percentage reads mapped: 80.75
Median coverage: 0.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4 | Euro-American | None | 1.0 |
lineage4.9 | Euro-American (H37Rv-like) | None | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474291 | n.634_649delTTTCCTCTCCGGAGGAinsC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpoA | 3877638 | c.870T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038740 | c.1965G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038767 | c.1938G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.9 | pyrazinamide | |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.9 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.83 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4038923 | c.1782A>G | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4038932 | c.1773G>C | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.7 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.7 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.7 | pyrazinamide |