TB-Profiler result

Run: SRR5074711
Summary

Run ID: SRR5074711

Sample name:

Date: 04-04-2023 09:09:20

Number of reads: 4319157

Percentage reads mapped: 86.14

Strain: lineage4.3.3

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.3 Euro-American (LAM) LAM;T RD115 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6408 p.Glu390Gly missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8040 p.Gly247Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.1
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.12
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.15
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.15
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.15
rrs 1472450 n.605A>C non_coding_transcript_exon_variant 0.14
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 0.15
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.17
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.21
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.1
rrs 1472495 n.650C>A non_coding_transcript_exon_variant 0.11
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.11
rrs 1472507 n.662C>A non_coding_transcript_exon_variant 0.11
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.17
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.17
rrs 1472545 n.700A>G non_coding_transcript_exon_variant 0.11
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.17
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.11
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.11
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.14
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.23
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.28
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.2
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.13
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.11
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.1
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.11
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.1
rrs 1472767 n.922G>C non_coding_transcript_exon_variant 0.14
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.13
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.11
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.11
rrs 1472812 n.967A>T non_coding_transcript_exon_variant 0.11
rrl 1474218 n.561T>G non_coding_transcript_exon_variant 0.17
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.25
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 0.29
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.29
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.29
rrl 1474269 n.612C>A non_coding_transcript_exon_variant 0.29
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.29
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.25
rrl 1474287 n.631_649delCCTTTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.25
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.22
rrl 1474752 n.1096delA non_coding_transcript_exon_variant 0.13
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.13
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.13
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.14
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.14
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.11
rrl 1474799 n.1143delT non_coding_transcript_exon_variant 0.12
rrl 1474803 n.1146_1147insA non_coding_transcript_exon_variant 0.12
rrl 1474806 n.1149A>C non_coding_transcript_exon_variant 0.12
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.15
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.15
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.15
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.15
rrl 1475690 n.2033G>T non_coding_transcript_exon_variant 0.12
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.11
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.11
rrl 1475830 n.2173G>A non_coding_transcript_exon_variant 0.11
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.12
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.15
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.11
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.14
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.14
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.12
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.11
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 0.17
PPE35 2170053 p.Thr187Ser missense_variant 0.15
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518919 p.Gly269Ser missense_variant 1.0
Rv2752c 3065824 p.Pro123Leu missense_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878641 c.-134C>G upstream_gene_variant 0.15
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 0.99
aftB 4269300 c.-464G>A upstream_gene_variant 1.0
whiB6 4338312 c.209_210insT frameshift_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0