TB-Profiler result

Run: SRR7131031
Summary

Run ID: SRR7131031

Sample name:

Date: 04-04-2023 18:42:35

Number of reads: 2814630

Percentage reads mapped: 99.99

Strain: lineage4.2.2.2

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
lineage4.2.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.31 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8688 p.Ala463Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576077 c.730C>T synonymous_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.28
mshA 576482 p.Val379Leu missense_variant 0.18
rpoB 761489 c.1683G>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.16
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.11
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.18
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.12
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.34
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.38
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.38
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.42
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.47
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.46
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.48
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.48
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.47
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.44
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.43
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.52
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.53
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.53
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.53
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.56
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.41
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.33
rrs 1472668 n.825_829delGGGTT non_coding_transcript_exon_variant 0.14
rrs 1472680 n.835C>T non_coding_transcript_exon_variant 0.11
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.14
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.24
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.24
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.34
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.34
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.27
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.27
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.19
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.18
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.19
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.16
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.11
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.11
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.11
rrl 1473978 n.321G>T non_coding_transcript_exon_variant 0.14
rrl 1474628 n.971C>T non_coding_transcript_exon_variant 0.12
rrl 1474635 n.979_982delACCG non_coding_transcript_exon_variant 0.14
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.2
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.29
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.27
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.46
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.31
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.46
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.43
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.43
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.54
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.38
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.38
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.12
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.4
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.35
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.29
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.31
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.16
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.13
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.13
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.13
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.17
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.17
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.17
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.32
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.32
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.32
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.4
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.33
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.32
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.32
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.31
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.31
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.31
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.31
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.31
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.3
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.3
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.32
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.38
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.4
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.45
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.45
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.43
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.47
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.46
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.46
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.42
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.49
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.49
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.41
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.26
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3066280 c.-89C>T upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
alr 3840746 p.Gln225His missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.59
embB 4247028 p.Leu172Arg missense_variant 0.21
whiB6 4338595 c.-75delG upstream_gene_variant 1.0