Run ID: SRR11342635
Sample name:
Date: 02-04-2023 20:46:52
Number of reads: 2534285
Percentage reads mapped: 36.81
Strain: lineage4.8
Drug-resistance: MDR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.8 | Euro-American (mainly T) | T1;T2;T3;T5 | RD219 | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761155 | p.Ser450Leu | missense_variant | 1.0 | rifampicin |
rpoC | 764363 | p.Gly332Arg | missense_variant | 0.78 | rifampicin |
katG | 2154857 | p.Asp419His | missense_variant | 1.0 | isoniazid |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
mshA | 576113 | p.Arg256Gly | missense_variant | 0.27 |
rpoC | 764916 | p.Leu516Pro | missense_variant | 0.14 |
rpoC | 766487 | p.Pro1040Ser | missense_variant | 0.23 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
fbiC | 1302983 | p.Pro18Leu | missense_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrs | 1472204 | n.359G>A | non_coding_transcript_exon_variant | 0.15 |
rrs | 1472214 | n.369C>G | non_coding_transcript_exon_variant | 0.13 |
rrs | 1472545 | n.700A>T | non_coding_transcript_exon_variant | 0.12 |
rrs | 1472598 | n.753A>C | non_coding_transcript_exon_variant | 0.12 |
rrs | 1472599 | n.754G>T | non_coding_transcript_exon_variant | 0.12 |
rrs | 1472655 | n.810G>A | non_coding_transcript_exon_variant | 0.12 |
rrs | 1472715 | n.870C>T | non_coding_transcript_exon_variant | 0.15 |
rrs | 1472719 | n.874G>A | non_coding_transcript_exon_variant | 0.18 |
rrs | 1472733 | n.888G>C | non_coding_transcript_exon_variant | 0.21 |
rrs | 1472734 | n.889C>A | non_coding_transcript_exon_variant | 0.2 |
rrs | 1472741 | n.896G>T | non_coding_transcript_exon_variant | 0.2 |
rrs | 1472742 | n.897C>G | non_coding_transcript_exon_variant | 0.23 |
rrs | 1472744 | n.899A>G | non_coding_transcript_exon_variant | 0.32 |
rrs | 1472781 | n.936C>T | non_coding_transcript_exon_variant | 0.31 |
rrs | 1472793 | n.948A>T | non_coding_transcript_exon_variant | 0.29 |
rrs | 1472805 | n.960C>A | non_coding_transcript_exon_variant | 0.18 |
rrs | 1472806 | n.961A>T | non_coding_transcript_exon_variant | 0.18 |
rrs | 1472813 | n.968A>G | non_coding_transcript_exon_variant | 0.2 |
rrs | 1473128 | n.1283C>A | non_coding_transcript_exon_variant | 0.16 |
rrs | 1473134 | n.1289T>A | non_coding_transcript_exon_variant | 0.26 |
rrs | 1473148 | n.1303G>A | non_coding_transcript_exon_variant | 0.31 |
rrs | 1473163 | n.1318C>T | non_coding_transcript_exon_variant | 0.32 |
rrs | 1473172 | n.1327T>C | non_coding_transcript_exon_variant | 0.32 |
rrs | 1473173 | n.1328C>T | non_coding_transcript_exon_variant | 0.33 |
rrs | 1473177 | n.1332G>A | non_coding_transcript_exon_variant | 0.31 |
rrs | 1473191 | n.1346C>G | non_coding_transcript_exon_variant | 0.3 |
rrs | 1473193 | n.1348G>T | non_coding_transcript_exon_variant | 0.3 |
rrs | 1473200 | n.1355A>C | non_coding_transcript_exon_variant | 0.3 |
rrs | 1473202 | n.1357C>T | non_coding_transcript_exon_variant | 0.3 |
rrs | 1473204 | n.1359C>A | non_coding_transcript_exon_variant | 0.32 |
rrs | 1473206 | n.1361G>C | non_coding_transcript_exon_variant | 0.32 |
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 |
rrl | 1475803 | n.2146T>C | non_coding_transcript_exon_variant | 0.12 |
rrl | 1475804 | n.2147G>C | non_coding_transcript_exon_variant | 0.12 |
rrl | 1475816 | n.2159C>G | non_coding_transcript_exon_variant | 0.14 |
rrl | 1475817 | n.2160A>G | non_coding_transcript_exon_variant | 0.15 |
rrl | 1475869 | n.2212C>T | non_coding_transcript_exon_variant | 0.13 |
rrl | 1476322 | n.2665C>A | non_coding_transcript_exon_variant | 0.43 |
rrl | 1476336 | n.2679C>G | non_coding_transcript_exon_variant | 0.68 |
rrl | 1476358 | n.2701T>C | non_coding_transcript_exon_variant | 0.79 |
rrl | 1476368 | n.2711T>C | non_coding_transcript_exon_variant | 0.78 |
rrl | 1476369 | n.2712C>T | non_coding_transcript_exon_variant | 0.79 |
rrl | 1476372 | n.2715T>C | non_coding_transcript_exon_variant | 0.8 |
rrl | 1476382 | n.2725A>G | non_coding_transcript_exon_variant | 0.81 |
rrl | 1476383 | n.2726T>G | non_coding_transcript_exon_variant | 0.81 |
rrl | 1476411 | n.2754G>A | non_coding_transcript_exon_variant | 0.82 |
rrl | 1476428 | n.2771C>A | non_coding_transcript_exon_variant | 0.81 |
rrl | 1476463 | n.2806C>T | non_coding_transcript_exon_variant | 0.74 |
rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.66 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
PPE35 | 2168149 | p.Pro822Ser | missense_variant | 1.0 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
fbiD | 3339734 | p.Ala206Gly | missense_variant | 0.15 |
Rv3083 | 3448497 | c.-7T>A | upstream_gene_variant | 1.0 |
rpoA | 3878613 | c.-106A>C | upstream_gene_variant | 0.25 |
rpoA | 3878618 | c.-111A>C | upstream_gene_variant | 0.13 |
clpC1 | 4039729 | p.Asp326Asn | missense_variant | 1.0 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
embB | 4247028 | p.Leu172Arg | missense_variant | 0.17 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |
Rv3083 | 3448507 | c.5_*1408del | frameshift_variant&stop_lost&splice_region_variant | 1.0 |