TB-Profiler result

Run: SRR22048392
Summary

Run ID: SRR22048392

Sample name:

Date: 04-04-2023 03:46:03

Number of reads: 2556521

Percentage reads mapped: 85.26

Strain: lineage4.8

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.42 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoB 760975 p.Met390Thr missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.11
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.11
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.11
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.24
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.24
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.29
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.29
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.33
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.33
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.31
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.32
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.39
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.38
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.47
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.58
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.56
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.54
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.51
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.43
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.49
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.5
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.5
rrs 1472687 n.842_843insC non_coding_transcript_exon_variant 0.5
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.5
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.5
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.47
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.47
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.35
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.35
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.22
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474483 n.826C>T non_coding_transcript_exon_variant 0.11
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.11
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.12
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.12
rrl 1474497 n.840G>A non_coding_transcript_exon_variant 0.12
rrl 1474506 n.849C>T non_coding_transcript_exon_variant 0.11
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.11
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.11
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.11
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.11
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.11
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.11
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.11
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.11
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.11
rrl 1474551 n.894G>A non_coding_transcript_exon_variant 0.1
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.1
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.11
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.11
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.11
rrl 1474709 n.1052G>A non_coding_transcript_exon_variant 0.1
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.11
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.1
rrl 1475090 n.1433A>C non_coding_transcript_exon_variant 1.0
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.13
rrl 1475760 n.2103C>A non_coding_transcript_exon_variant 0.14
rrl 1475762 n.2105G>C non_coding_transcript_exon_variant 0.15
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.17
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.11
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.12
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.14
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.14
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.14
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.14
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.14
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.14
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.16
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.16
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.16
rrl 1476214 n.2557G>C non_coding_transcript_exon_variant 0.16
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.16
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.49
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.46
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.46
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.49
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.49
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.49
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.49
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.47
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.45
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.45
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.45
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.44
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.42
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.43
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.43
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.46
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.46
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.46
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.58
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.62
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.67
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.66
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.57
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.57
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.55
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.55
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.56
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.57
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.56
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.4
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 0.99
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086767 c.-53A>C upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
Rv3083 3448500 c.-4A>G upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244990 c.1758G>C synonymous_variant 1.0
aftB 4267715 c.1122G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0