TB-Profiler result

Run: SRR6046609
Summary

Run ID: SRR6046609

Sample name:

Date: 04-04-2023 12:19:54

Number of reads: 11770

Percentage reads mapped: 1.73

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 762896 c.-474G>C upstream_gene_variant 1.0
rpoC 762917 c.-453C>G upstream_gene_variant 1.0
rpoC 762923 c.-447C>G upstream_gene_variant 1.0
rpoB 762925 p.Thr1040Ile missense_variant 1.0
rpoC 762929 c.-441G>C upstream_gene_variant 1.0
rpoB 762939 p.Met1045Leu missense_variant 1.0
rpoB 762942 p.Ile1046Val missense_variant 1.0
rpoC 762956 c.-414G>C upstream_gene_variant 1.0
rpoC 762965 c.-405T>C upstream_gene_variant 1.0
rpoC 762980 c.-390T>C upstream_gene_variant 1.0
rpoC 762989 c.-381G>C upstream_gene_variant 1.0
rpoC 762995 c.-375G>T upstream_gene_variant 1.0
rpoB 763005 p.Cys1067Val missense_variant 1.0
rpoC 763013 c.-357C>G upstream_gene_variant 1.0
rpoB 763014 p.Met1070Leu missense_variant 1.0
rpoB 763017 p.Gln1071Glu missense_variant 1.0
rpoC 763031 c.-339T>G upstream_gene_variant 1.0
rpoC 764611 c.1242G>C synonymous_variant 1.0
rpoC 764632 c.1263T>C synonymous_variant 1.0
rpoC 764650 c.1281G>C synonymous_variant 1.0
rpoC 764665 c.1296C>T synonymous_variant 1.0
rpoC 764668 c.1299C>T synonymous_variant 1.0
rpoC 764671 c.1302G>C synonymous_variant 1.0
rpoC 764672 p.Gln435Glu missense_variant 1.0
rpoC 764677 c.1308C>G synonymous_variant 1.0
rpoC 764695 c.1326T>C synonymous_variant 1.0
rpoC 764701 c.1332C>G synonymous_variant 1.0
rpoC 764705 p.Leu446Lys missense_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 1.0
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 1.0
rrs 1472129 n.284G>A non_coding_transcript_exon_variant 1.0
rrs 1472135 n.290C>T non_coding_transcript_exon_variant 1.0
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 1.0
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 1.0
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 1.0
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 1.0
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 1.0
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 1.0
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>G non_coding_transcript_exon_variant 1.0
rrl 1476356 n.2699C>G non_coding_transcript_exon_variant 1.0
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 1.0
rrl 1476384 n.2727G>C non_coding_transcript_exon_variant 1.0
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 1.0
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 1.0
rrl 1476428 n.2771C>A non_coding_transcript_exon_variant 1.0
rrl 1476443 n.2786G>C non_coding_transcript_exon_variant 1.0
rrl 1476455 n.2798C>G non_coding_transcript_exon_variant 1.0
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 1.0
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 1.0