TB-Profiler result

Run: ERR126611
Summary

Run ID: ERR126611

Sample name:

Date: 31-03-2023 12:57:08

Number of reads: 4282752

Percentage reads mapped: 60.32

Strain: lineage4.9.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
lineage4.9.1 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8978 c.1677C>T synonymous_variant 1.0
fgd1 490751 c.-32T>G upstream_gene_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472714 n.869A>C non_coding_transcript_exon_variant 0.19
rrs 1472715 n.870C>G non_coding_transcript_exon_variant 0.18
rrs 1472716 n.871C>A non_coding_transcript_exon_variant 0.18
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.45
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.43
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.42
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.4
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.34
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.19
rrs 1472827 n.982G>C non_coding_transcript_exon_variant 0.14
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.14
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.23
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.24
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.23
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.24
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.22
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.23
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.23
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.21
rrs 1473097 n.1252G>C non_coding_transcript_exon_variant 0.19
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.19
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.17
rrs 1473164 n.1319C>G non_coding_transcript_exon_variant 0.17
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.17
rrs 1473191 n.1346C>T non_coding_transcript_exon_variant 0.17
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.17
rrs 1473193 n.1348G>A non_coding_transcript_exon_variant 0.16
rrs 1473198 n.1354delC non_coding_transcript_exon_variant 0.17
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.17
rrs 1473204 n.1359C>T non_coding_transcript_exon_variant 0.16
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.16
rrs 1473206 n.1361G>A non_coding_transcript_exon_variant 0.16
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.32
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.36
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.36
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.36
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.36
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.4
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.4
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.4
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.4
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.4
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.54
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.56
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.55
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.54
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.49
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.49
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.46
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.46
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.44
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.43
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289138 p.Leu35Arg missense_variant 1.0
fbiD 3339385 p.Asp90Asn missense_variant 0.99
clpC1 4038857 c.1848C>A synonymous_variant 0.27
whiB6 4338595 c.-75delG upstream_gene_variant 1.0