TB-Profiler result

Run: SRR6045024
Summary

Run ID: SRR6045024

Sample name:

Date: 04-04-2023 11:51:43

Number of reads: 1380996

Percentage reads mapped: 81.43

Strain: lineage4.1.1.2

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.2 Euro-American (X-type) X1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.52 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576750 p.Lys468Thr missense_variant 0.18
ccsA 620748 c.858T>G synonymous_variant 0.24
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302814 c.-117C>T upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.21
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.32
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.39
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.58
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.6
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.65
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.65
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.65
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.65
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.52
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.43
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.64
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.61
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.61
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.61
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.57
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.52
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.5
rrs 1472668 n.825_829delGGGTT non_coding_transcript_exon_variant 0.36
rrs 1472675 n.830_831insAGAC non_coding_transcript_exon_variant 0.36
rrs 1472680 n.835C>T non_coding_transcript_exon_variant 0.3
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.48
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.14
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.52
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.52
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.45
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.45
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.25
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.22
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.24
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.33
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.2
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.18
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.13
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.16
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.1
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.18
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.17
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.17
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.17
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.17
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.17
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.17
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.15
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.21
rrl 1474801 n.1144G>A non_coding_transcript_exon_variant 0.21
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.21
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.25
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.2
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.2
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.2
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.25
rrl 1475226 n.1569C>T non_coding_transcript_exon_variant 0.2
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.18
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.14
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.14
rrl 1475874 n.2217C>T non_coding_transcript_exon_variant 0.13
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.1
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.1
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.14
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.14
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.14
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.14
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.11
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.11
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.12
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.19
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.12
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.17
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.14
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.14
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.14
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.14
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.35
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.35
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.35
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.53
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.53
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.53
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.55
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.57
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.48
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.48
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.48
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.47
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.45
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.42
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.44
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.45
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.45
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.47
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.55
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.55
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.53
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.58
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.56
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.56
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.56
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.56
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.51
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.51
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.51
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.31
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.35
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170066 p.Ala183Thr missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449787 c.1284C>T synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embC 4241572 c.1710C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243833 p.Ala201Thr missense_variant 1.0
embB 4246930 p.Gln139His missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0