TB-Profiler result

Run: ERR4816755
Summary

Run ID: ERR4816755

Sample name:

Date: 01-04-2023 14:36:49

Number of reads: 1395934

Percentage reads mapped: 45.59

Strain: lineage4.1.1.3

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 0.99
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.22 streptomycin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.27 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5157 c.-83C>T upstream_gene_variant 0.13
gyrB 5484 p.Arg82Leu missense_variant 0.18
gyrB 5713 c.476delA frameshift_variant 0.13
gyrA 6439 c.-863C>T upstream_gene_variant 0.17
gyrA 6523 c.-779G>T upstream_gene_variant 0.14
gyrB 6567 p.Ala443Gly missense_variant 0.12
gyrB 6836 p.Ala533Ser missense_variant 0.17
gyrB 6849 p.Gly537Val missense_variant 0.17
gyrB 6966 p.Ser576Ile missense_variant 0.12
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7522 p.Ala74Asp missense_variant 0.12
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7686 c.388_389delAC frameshift_variant 0.14
gyrA 7966 p.Arg222Leu missense_variant 0.15
gyrA 8706 p.Leu469Met missense_variant 0.22
gyrA 8738 c.1437G>A synonymous_variant 0.14
gyrA 8748 p.Leu483Ile missense_variant 0.12
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490595 c.-188G>A upstream_gene_variant 0.14
fgd1 490799 p.Leu6Pro missense_variant 0.11
mshA 575582 c.236delT frameshift_variant 0.11
mshA 575588 p.Arg81Ser missense_variant 0.12
mshA 575649 p.Val101Ala missense_variant 0.14
mshA 576104 p.Arg253Ser missense_variant 0.17
mshA 576113 c.766C>A synonymous_variant 0.17
ccsA 619984 p.Leu32Val missense_variant 0.12
ccsA 620157 c.267G>T synonymous_variant 0.15
ccsA 620661 c.771C>A synonymous_variant 0.17
ccsA 620743 p.Ala285Ser missense_variant 0.2
rpoB 760232 p.Lys142Asn missense_variant 0.17
rpoB 760722 p.Gly306Cys missense_variant 0.15
rpoB 761016 p.Glu404* stop_gained 0.22
rpoB 761364 p.Asp520Tyr missense_variant 0.18
rpoB 761403 p.His533Asn missense_variant 0.14
rpoB 761896 p.Ala697Asp missense_variant 0.2
rpoB 762870 p.Met1022Val missense_variant 0.1
rpoB 762879 p.Met1025Leu missense_variant 0.14
rpoB 762888 p.His1028Ala missense_variant 0.2
rpoC 762896 c.-474G>C upstream_gene_variant 0.13
rpoC 762899 c.-471G>C upstream_gene_variant 0.13
rpoC 762917 c.-453C>T upstream_gene_variant 0.13
rpoC 762920 c.-450C>G upstream_gene_variant 0.27
rpoC 762929 c.-441G>C upstream_gene_variant 0.25
rpoC 763053 c.-317T>C upstream_gene_variant 0.17
rpoC 763067 c.-303C>G upstream_gene_variant 0.1
rpoC 763103 c.-267G>C upstream_gene_variant 0.22
rpoC 763115 c.-255T>C upstream_gene_variant 0.18
rpoC 763453 c.84C>G synonymous_variant 0.1
rpoC 763456 c.87A>G synonymous_variant 0.15
rpoC 763462 c.93G>C synonymous_variant 0.1
rpoC 763468 c.99G>C synonymous_variant 0.11
rpoC 763486 c.117T>G synonymous_variant 0.16
rpoC 763492 c.123G>C synonymous_variant 0.11
rpoC 763504 c.135C>G synonymous_variant 0.11
rpoC 763507 c.138G>C synonymous_variant 0.13
rpoC 763534 c.165T>C synonymous_variant 0.19
rpoC 763546 c.177A>G synonymous_variant 0.22
rpoC 764326 c.957G>C synonymous_variant 0.14
rpoC 764365 c.996C>T synonymous_variant 0.14
rpoC 764371 c.1002G>C synonymous_variant 0.14
rpoC 764377 c.1008C>G synonymous_variant 0.15
rpoC 764380 c.1011G>C synonymous_variant 0.2
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.24
rpoC 764401 c.1032C>T synonymous_variant 0.16
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.21
rpoC 764410 c.1041G>C synonymous_variant 0.12
rpoC 764428 c.1059G>C synonymous_variant 0.14
rpoC 764434 c.1065A>G synonymous_variant 0.13
rpoC 764435 c.1066A>C synonymous_variant 0.13
rpoC 764443 p.Ile358Met missense_variant 0.11
rpoC 764446 p.Asp359Glu missense_variant 0.17
rpoC 764450 p.Gly361Arg missense_variant 0.19
rpoC 764458 c.1089G>C synonymous_variant 0.13
rpoC 764461 p.Glu364Asp missense_variant 0.21
rpoC 764471 p.Asn368Arg missense_variant 0.15
rpoC 764479 c.1110G>A synonymous_variant 0.15
rpoC 764497 c.1128A>G synonymous_variant 0.12
rpoC 764503 c.1134G>C synonymous_variant 0.15
rpoC 764509 c.1140G>C synonymous_variant 0.17
rpoC 764530 c.1161C>T synonymous_variant 0.14
rpoC 764536 c.1167G>T synonymous_variant 0.12
rpoC 764539 c.1170C>G synonymous_variant 0.12
rpoC 764560 c.1191T>C synonymous_variant 0.14
rpoC 764575 c.1206T>G synonymous_variant 0.23
rpoC 764581 c.1212T>C synonymous_variant 0.22
rpoC 764582 p.Leu405Met missense_variant 0.22
rpoC 764605 c.1236G>C synonymous_variant 0.17
rpoC 764611 c.1242G>C synonymous_variant 0.22
rpoC 764632 c.1263T>C synonymous_variant 0.31
rpoC 764644 c.1275G>C synonymous_variant 0.17
rpoC 764650 c.1281G>C synonymous_variant 0.13
rpoC 764662 c.1293G>C synonymous_variant 0.18
rpoC 764664 p.Val432Ala missense_variant 0.12
rpoC 764677 c.1308C>G synonymous_variant 0.14
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 765527 p.Gly720Ser missense_variant 0.12
rpoC 765553 c.2184C>A synonymous_variant 0.14
rpoC 765610 p.Asp747Glu missense_variant 0.14
rpoC 765832 p.Lys821Asn missense_variant 0.12
rpoC 765947 c.2578T>C synonymous_variant 0.11
rpoC 766363 c.2994G>C synonymous_variant 0.12
rpoC 766369 c.3000C>G synonymous_variant 0.18
rpoC 766402 c.3033C>T synonymous_variant 0.2
rpoC 766716 p.Ala1116Val missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776609 p.Met624Ile missense_variant 0.14
mmpL5 777157 c.1324C>A synonymous_variant 0.2
mmpS5 778554 p.Val118Phe missense_variant 0.2
mmpL5 779112 c.-632G>T upstream_gene_variant 0.12
mmpR5 779186 p.Gly66Val missense_variant 0.13
mmpS5 779652 c.-747G>T upstream_gene_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781668 p.Val37Met missense_variant 0.15
rplC 800700 c.-109C>A upstream_gene_variant 0.14
rplC 801231 c.423C>A synonymous_variant 0.17
rplC 801236 p.Ala143Val missense_variant 0.14
fbiC 1303264 p.Gly112Ser missense_variant 0.14
fbiC 1304751 c.1821C>T synonymous_variant 0.13
fbiC 1304752 p.Glu608* stop_gained 0.13
fbiC 1304789 p.Ala620Asp missense_variant 0.13
Rv1258c 1406677 p.Leu222Met missense_variant 0.12
Rv1258c 1407505 c.-165G>T upstream_gene_variant 0.12
embR 1416222 p.Phe376Leu missense_variant 0.35
embR 1416232 p.Cys372Gly missense_variant 0.38
embR 1416259 c.1089G>C synonymous_variant 0.33
embR 1416262 c.1086G>C synonymous_variant 0.15
embR 1416502 p.Met282Ile missense_variant 0.14
embR 1416568 c.780G>C synonymous_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472094 n.249T>G non_coding_transcript_exon_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0
rrs 1472120 n.275G>T non_coding_transcript_exon_variant 0.5
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.33
rrs 1472146 n.301G>T non_coding_transcript_exon_variant 0.25
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.75
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.25
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.13
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.89
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.15
rrs 1472210 n.365A>T non_coding_transcript_exon_variant 0.25
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.5
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.1
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.18
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.12
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.47
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.64
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.55
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.71
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.33
rrs 1472303 n.458G>T non_coding_transcript_exon_variant 1.0
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.5
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.5
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.5
rrs 1472338 n.493A>C non_coding_transcript_exon_variant 0.18
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.45
rrs 1472374 n.529T>G non_coding_transcript_exon_variant 0.25
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.18
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.18
rrs 1472382 n.537G>T non_coding_transcript_exon_variant 0.22
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.22
rrs 1472390 n.545T>A non_coding_transcript_exon_variant 0.22
rrs 1472391 n.546C>T non_coding_transcript_exon_variant 0.44
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.33
rrs 1472412 n.567A>C non_coding_transcript_exon_variant 0.5
rrs 1472415 n.570T>A non_coding_transcript_exon_variant 0.4
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.67
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 1.0
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.29
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.29
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.29
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.25
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.25
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.38
rrs 1472583 n.738T>A non_coding_transcript_exon_variant 0.25
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.29
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.33
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.22
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.29
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.33
rrs 1472659 n.814G>A non_coding_transcript_exon_variant 0.33
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.33
rrs 1472664 n.819A>C non_coding_transcript_exon_variant 0.33
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.5
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.24
rrs 1472714 n.869A>T non_coding_transcript_exon_variant 0.29
rrs 1472715 n.870C>G non_coding_transcript_exon_variant 0.5
rrs 1472716 n.871C>A non_coding_transcript_exon_variant 0.5
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.21
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.21
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.56
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.29
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.48
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.7
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.17
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.7
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.5
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.4
rrs 1472827 n.982G>C non_coding_transcript_exon_variant 0.33
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.83
rrs 1472887 n.1042G>C non_coding_transcript_exon_variant 0.5
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.25
rrs 1472951 n.1106T>C non_coding_transcript_exon_variant 0.17
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.62
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.83
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.23
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.5
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.25
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.5
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.2
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.55
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.5
rrs 1472996 n.1151T>C non_coding_transcript_exon_variant 0.15
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.27
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.25
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.29
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.38
rrs 1473026 n.1181T>C non_coding_transcript_exon_variant 0.11
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.5
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.15
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.3
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.38
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.56
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.25
rrs 1473091 n.1246G>T non_coding_transcript_exon_variant 0.22
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.22
rrs 1473100 n.1255G>C non_coding_transcript_exon_variant 0.4
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.25
rrs 1473109 n.1264T>G non_coding_transcript_exon_variant 0.25
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.5
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.75
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 1.0
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 1.0
rrs 1473128 n.1283C>T non_coding_transcript_exon_variant 0.33
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 1.0
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.92
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.15
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.27
rrs 1473179 n.1334C>T non_coding_transcript_exon_variant 0.2
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.53
rrs 1473195 n.1350T>A non_coding_transcript_exon_variant 0.12
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.36
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.6
rrs 1473207 n.1362C>T non_coding_transcript_exon_variant 0.13
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.17
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.15
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.15
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.15
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.77
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.15
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.8
rrs 1473282 n.1437C>G non_coding_transcript_exon_variant 0.2
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.5
rrs 1473288 n.1443C>G non_coding_transcript_exon_variant 0.25
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.6
rrs 1473291 n.1446_1447insC non_coding_transcript_exon_variant 0.5
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.55
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.17
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.36
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.27
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.18
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.18
rrl 1473414 n.-244G>T upstream_gene_variant 0.12
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 1.0
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0
rrl 1473768 n.111A>G non_coding_transcript_exon_variant 0.67
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.67
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.67
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 1.0
rrl 1474234 n.577G>T non_coding_transcript_exon_variant 0.5
rrl 1474237 n.580A>C non_coding_transcript_exon_variant 0.5
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 1.0
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.4
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.71
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.29
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.44
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.44
rrl 1474507 n.850G>A non_coding_transcript_exon_variant 0.29
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.78
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.2
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.22
rrl 1474534 n.877G>A non_coding_transcript_exon_variant 0.2
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.29
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.4
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.6
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.57
rrl 1474584 n.927C>G non_coding_transcript_exon_variant 0.29
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.29
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0
rrl 1474638 n.981C>A non_coding_transcript_exon_variant 1.0
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 1.0
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.67
rrl 1474664 n.1007G>A non_coding_transcript_exon_variant 0.67
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0
rrl 1474717 n.1060A>G non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474777 n.1120T>A non_coding_transcript_exon_variant 0.67
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.67
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.4
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.67
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.33
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.55
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.7
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.7
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.7
rrl 1474938 n.1281G>A non_coding_transcript_exon_variant 0.5
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.4
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.4
rrl 1475481 n.1824C>T non_coding_transcript_exon_variant 0.5
rrl 1475482 n.1825A>T non_coding_transcript_exon_variant 0.5
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 0.25
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.67
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 0.67
rrl 1475756 n.2101_2108delACCCGCAA non_coding_transcript_exon_variant 1.0
rrl 1475768 n.2111G>C non_coding_transcript_exon_variant 1.0
rrl 1475769 n.2112_2113insTCGGCC non_coding_transcript_exon_variant 1.0
rrl 1475874 n.2217C>T non_coding_transcript_exon_variant 0.19
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.21
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.21
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.56
rrl 1475892 n.2235A>G non_coding_transcript_exon_variant 0.11
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.1
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.25
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.21
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.24
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.17
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.22
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.57
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.33
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.33
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.25
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.25
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.6
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.5
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 1.0
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.5
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.4
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.6
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 1.0
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 1.0
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.75
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.75
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.8
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.5
rrl 1476366 n.2709A>C non_coding_transcript_exon_variant 0.14
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.18
rrl 1476374 n.2717T>G non_coding_transcript_exon_variant 0.18
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.75
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.23
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.21
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.24
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.7
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.32
rrl 1476455 n.2798C>G non_coding_transcript_exon_variant 0.11
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.22
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.53
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.5
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 1.0
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.5
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.5
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.5
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.5
inhA 1674472 p.Val91Met missense_variant 0.15
inhA 1674818 p.Ala206Glu missense_variant 0.14
rpsA 1833694 c.153G>C synonymous_variant 0.14
rpsA 1833697 c.156C>G synonymous_variant 0.14
rpsA 1833721 c.180A>G synonymous_variant 0.17
rpsA 1833727 c.186G>C synonymous_variant 0.14
rpsA 1833734 p.Ala65Ser missense_variant 0.14
rpsA 1833737 p.Arg66Ser missense_variant 0.17
rpsA 1833742 c.201A>G synonymous_variant 0.24
rpsA 1833766 c.225C>T synonymous_variant 0.15
rpsA 1833770 p.Asn77Gly missense_variant 0.2
rpsA 1833780 c.240_242delTTC disruptive_inframe_deletion 0.22
rpsA 1833785 c.244_245insAGA disruptive_inframe_insertion 0.18
rpsA 1833790 c.249T>C synonymous_variant 0.18
rpsA 1833802 p.Glu87Asp missense_variant 0.13
rpsA 1833808 c.267G>C synonymous_variant 0.12
rpsA 1833811 c.270G>C synonymous_variant 0.12
rpsA 1833829 c.288A>G synonymous_variant 0.12
rpsA 1833910 c.369C>T synonymous_variant 0.18
rpsA 1833955 c.414G>C synonymous_variant 0.1
rpsA 1833979 c.438T>C synonymous_variant 0.11
rpsA 1833991 c.450C>G synonymous_variant 0.14
rpsA 1834034 p.Ile165Val missense_variant 0.13
rpsA 1834040 p.Lys167Gln missense_variant 0.1
rpsA 1834069 c.528G>C synonymous_variant 0.11
rpsA 1834090 c.549G>C synonymous_variant 0.11
rpsA 1834366 c.825A>G synonymous_variant 0.12
rpsA 1834411 c.870T>C synonymous_variant 0.11
rpsA 1834451 c.910T>C synonymous_variant 0.11
tlyA 1917943 p.Ala2Ser missense_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918282 p.Tyr115His missense_variant 0.1
ndh 2102290 p.Asp251Ala missense_variant 0.15
ndh 2102367 p.Ala226Thr missense_variant 0.17
ndh 2102804 p.Arg80Leu missense_variant 0.12
ndh 2102983 c.60C>A synonymous_variant 0.13
katG 2154838 p.Arg425Ile missense_variant 0.13
katG 2154991 p.Ser374Tyr missense_variant 0.13
katG 2155081 p.Thr344Met missense_variant 0.33
katG 2155271 p.Ala281Ser missense_variant 0.22
katG 2155719 c.393G>C synonymous_variant 0.11
katG 2156096 p.Pro6Ser missense_variant 1.0
PPE35 2168328 p.Pro762Arg missense_variant 0.17
PPE35 2168722 p.Ala631Ser missense_variant 0.25
PPE35 2169521 c.1092G>A synonymous_variant 0.17
PPE35 2170416 p.Ala66Val missense_variant 0.13
PPE35 2170556 c.57G>T synonymous_variant 0.15
Rv1979c 2221761 c.1404C>T synonymous_variant 0.17
Rv1979c 2222212 p.Ala318Val missense_variant 0.17
Rv1979c 2222718 c.447G>A synonymous_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv1979c 2223319 c.-155C>A upstream_gene_variant 0.14
pncA 2290041 c.-800C>A upstream_gene_variant 0.15
pncA 2290123 c.-882G>T upstream_gene_variant 0.13
eis 2714704 p.Gly210Glu missense_variant 0.15
eis 2715496 c.-164C>T upstream_gene_variant 1.0
ahpC 2726245 p.Leu18Arg missense_variant 0.11
ahpC 2726257 p.Asp22Gly missense_variant 0.11
ahpC 2726691 c.502delC frameshift_variant 0.12
folC 2746684 c.915C>A synonymous_variant 0.17
folC 2746715 p.Gly295Asp missense_variant 0.13
folC 2746893 p.Arg236Cys missense_variant 0.17
folC 2746900 c.699C>A synonymous_variant 0.18
folC 2746916 p.Pro228Leu missense_variant 0.2
pepQ 2859394 p.Leu342* stop_gained 0.12
pepQ 2859439 p.Gly327Val missense_variant 0.17
pepQ 2859619 p.Gly267Asp missense_variant 0.22
pepQ 2859643 p.Ala259Asp missense_variant 0.14
pepQ 2860034 p.Glu129* stop_gained 0.12
thyX 3067760 c.186G>T synonymous_variant 0.12
thyX 3068105 c.-160C>A upstream_gene_variant 0.15
thyA 3073817 p.Gln219Lys missense_variant 0.12
thyA 3074151 p.Glu107Asp missense_variant 0.17
thyA 3074571 c.-100T>C upstream_gene_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086925 p.Gln36Glu missense_variant 0.12
ald 3087420 p.Ile201Val missense_variant 0.1
fbiD 3339094 c.-24G>A upstream_gene_variant 0.13
fbiD 3339274 p.Val53Phe missense_variant 0.14
fbiD 3339409 p.Ala98Thr missense_variant 0.2
Rv3083 3448780 p.Gly93Ser missense_variant 0.2
Rv3083 3449562 c.1059G>T synonymous_variant 0.33
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474603 c.597C>A synonymous_variant 0.25
fprA 3474997 p.Gly331Arg missense_variant 0.15
fprA 3475371 c.1365C>A synonymous_variant 0.25
Rv3236c 3612037 c.1079delT frameshift_variant 0.12
Rv3236c 3612454 c.663G>A synonymous_variant 0.17
Rv3236c 3612479 p.Pro213His missense_variant 0.17
Rv3236c 3612511 p.Trp202Cys missense_variant 0.18
fbiA 3640344 c.-199C>T upstream_gene_variant 0.18
fbiA 3640525 c.-18G>T upstream_gene_variant 0.25
fbiA 3640976 p.Ala145Asp missense_variant 0.25
fbiB 3642237 p.Pro235Thr missense_variant 0.13
fbiB 3642444 p.Ala304Thr missense_variant 0.12
alr 3840738 p.Arg228Leu missense_variant 0.13
alr 3841034 p.Gln129His missense_variant 0.29
alr 3841211 c.210C>T synonymous_variant 0.13
alr 3841546 c.-126C>T upstream_gene_variant 0.12
rpoA 3878677 c.-170C>T upstream_gene_variant 0.18
clpC1 4038422 p.Lys761Asn missense_variant 0.2
clpC1 4039074 p.Arg544Leu missense_variant 0.14
clpC1 4039487 c.1218G>C synonymous_variant 0.15
clpC1 4040336 c.369G>T synonymous_variant 0.15
panD 4043990 p.Ala98Thr missense_variant 0.12
panD 4044160 p.Gly41Val missense_variant 0.14
embC 4239676 c.-187T>A upstream_gene_variant 0.18
embC 4239933 p.Ala24Glu missense_variant 0.17
embC 4241677 c.1815G>A synonymous_variant 0.25
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4244214 p.Ala328Ser missense_variant 0.33
embA 4244233 p.Ala334Asp missense_variant 0.2
embA 4245690 p.Gly820Arg missense_variant 0.13
embB 4246815 p.Thr101Asn missense_variant 0.17
embB 4248673 c.2160G>A synonymous_variant 0.14
embB 4249408 c.2895G>A synonymous_variant 1.0
aftB 4268341 p.Pro166Thr missense_variant 0.15
ubiA 4269062 p.Ala258Ser missense_variant 0.13
ethR 4326952 c.-597G>A upstream_gene_variant 0.14
ethR 4327798 p.Asp84Tyr missense_variant 0.15
ethR 4328012 p.Ala155Asp missense_variant 0.18
ethR 4328101 p.Ala185Ser missense_variant 0.14
whiB6 4338175 p.Ala116Glu missense_variant 0.13
whiB6 4338594 c.-73T>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338677 c.-156G>T upstream_gene_variant 0.12
gid 4408085 p.Glu40Lys missense_variant 0.12