TB-Profiler result

Run: SRR16156291
Summary

Run ID: SRR16156291

Sample name:

Date: 03-04-2023 16:35:56

Number of reads: 57041

Percentage reads mapped: 2.08

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1473246 n.1401A>G non_coding_transcript_exon_variant 1.0 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472089 n.244C>T non_coding_transcript_exon_variant 0.83
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.9
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.95
rrs 1472108 n.263C>A non_coding_transcript_exon_variant 0.95
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.96
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 0.96
rrs 1472129 n.284G>T non_coding_transcript_exon_variant 0.96
rrs 1472135 n.290C>T non_coding_transcript_exon_variant 0.96
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.96
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.96
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.96
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.96
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 0.96
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472210 n.365A>T non_coding_transcript_exon_variant 0.96
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.96
rrs 1472223 n.378C>G non_coding_transcript_exon_variant 0.82
rrs 1472228 n.383G>C non_coding_transcript_exon_variant 0.82
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.96
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.95
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.94
rrs 1472251 n.406G>T non_coding_transcript_exon_variant 0.88
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.75
rrs 1472256 n.411T>A non_coding_transcript_exon_variant 0.75
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.75
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 1.0
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 1.0
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 1.0
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 1.0
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 1.0
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 1.0
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 1.0
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 1.0
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 1.0
rrl 1476411 n.2754G>T non_coding_transcript_exon_variant 1.0
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 1.0
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 1.0
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 1.0
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 1.0
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.95
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.95
rrl 1476463 n.2806C>A non_coding_transcript_exon_variant 0.97
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.97
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.97
rrl 1476483 n.2826G>A non_coding_transcript_exon_variant 0.95
rrl 1476501 n.2844C>T non_coding_transcript_exon_variant 0.89
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.89
Rv3083 3449642 p.Asn380Thr missense_variant 1.0
panD 4044281 c.1A>T initiator_codon_variant 0.67
embB 4248324 p.Ala604Gly missense_variant 0.5
ubiA 4269089 p.Ala249Thr missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0