TB-Profiler result

Run: SRR6046497
Summary

Run ID: SRR6046497

Sample name:

Date: 04-04-2023 12:17:54

Number of reads: 2925

Percentage reads mapped: 0.09

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.29 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 763145 c.-225G>A upstream_gene_variant 1.0
rpoC 763157 c.-213G>T upstream_gene_variant 1.0
rpoC 763166 c.-204A>G upstream_gene_variant 1.0
rpoC 763172 c.-198G>C upstream_gene_variant 1.0
rpoC 763365 c.-5_-4insT upstream_gene_variant 1.0
rpoC 763402 c.33C>T synonymous_variant 1.0
rpoC 763430 c.61A>C synonymous_variant 1.0
rpoC 763444 c.75T>C synonymous_variant 1.0
rpoC 763447 c.78C>T synonymous_variant 1.0
rpoC 763456 c.87A>G synonymous_variant 1.0
rpoC 763465 c.96G>A synonymous_variant 1.0
rpoC 763486 c.117T>C synonymous_variant 1.0
rpoC 763492 c.123G>C synonymous_variant 1.0
rpoC 763528 c.159G>A synonymous_variant 1.0
rpoC 763546 c.177A>G synonymous_variant 1.0
mmpL5 776705 c.1776C>T synonymous_variant 1.0
mmpL5 776735 c.1746C>T synonymous_variant 1.0
mmpL5 776738 p.Ile581Met missense_variant 1.0
mmpL5 776741 c.1740C>G synonymous_variant 1.0
mmpL5 776744 c.1737C>G synonymous_variant 1.0
rpsL 781667 c.108C>T synonymous_variant 1.0
rpsL 781682 c.123T>C synonymous_variant 1.0
rpsL 781703 c.144G>A synonymous_variant 1.0
rpsL 781706 c.147T>G synonymous_variant 1.0
rpsL 781709 c.150G>T synonymous_variant 1.0
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 1.0
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 1.0
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 1.0
rrs 1472378 n.533G>T non_coding_transcript_exon_variant 0.5
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 1.0
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.5
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 1.0
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 1.0
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 1.0
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.5
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.5
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 1.0
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 1.0
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.33
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 1.0
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.44
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.5
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.5
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.5
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 1.0
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.71
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.29
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.71
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.5
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 1.0
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 1.0
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 1.0
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.8
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 1.0
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 1.0
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 1.0
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 1.0
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 1.0
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 1.0
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 1.0
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 1.0
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 1.0
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 1.0
rrs 1473316 n.1471C>A non_coding_transcript_exon_variant 1.0
rrs 1473318 n.1473G>A non_coding_transcript_exon_variant 1.0
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 1.0
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 1.0
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 1.0
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 1.0
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 1.0
rrl 1473679 n.22T>C non_coding_transcript_exon_variant 1.0
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 1.0
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 1.0
rrl 1473718 n.61G>T non_coding_transcript_exon_variant 1.0
rrl 1473721 n.64G>A non_coding_transcript_exon_variant 1.0
rrl 1473722 n.65G>T non_coding_transcript_exon_variant 1.0
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 1.0
rrl 1474124 n.467G>C non_coding_transcript_exon_variant 1.0
rrl 1474125 n.468C>G non_coding_transcript_exon_variant 1.0
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 1.0
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 1.0
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 1.0
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 1.0
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 1.0
rrl 1474171 n.514C>T non_coding_transcript_exon_variant 0.67
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.5
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.62
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.73
rrl 1474199 n.542G>A non_coding_transcript_exon_variant 0.29
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.79
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.32
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.45
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.71
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.71
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.6
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.5
rrl 1474384 n.727C>T non_coding_transcript_exon_variant 0.5
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0
rrl 1474450 n.793T>A non_coding_transcript_exon_variant 1.0
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 1.0
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 1.0
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 1.0
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 1.0
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.25
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.75
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.75
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.33
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.33
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.67
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 1.0
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 1.0
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 1.0
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 1.0
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 1.0
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 1.0
rrl 1474584 n.927C>T non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 1.0
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 1.0
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1474883 n.1226T>C non_coding_transcript_exon_variant 0.71
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 1.0
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 1.0
rrl 1475515 n.1858G>A non_coding_transcript_exon_variant 1.0
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 1.0
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 1.0
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 1.0
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 1.0
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 1.0
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 1.0
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 1.0
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 1.0
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 1.0
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 1.0
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 1.0
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 1.0
rrl 1475757 n.2101_2104delACCC non_coding_transcript_exon_variant 1.0
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 1.0
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 1.0
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.42
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.38
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.45
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.48
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.32
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.31
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.62
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 1.0
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 1.0
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 1.0
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 1.0
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 1.0
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 1.0
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 1.0
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 1.0
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 1.0
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 1.0
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 1.0
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 1.0
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 1.0
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 1.0
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 1.0
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 1.0
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 1.0
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 1.0
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 1.0
rpsA 1834027 p.Gln162His missense_variant 1.0
rpsA 1834039 c.498C>T synonymous_variant 1.0
rpsA 1834040 p.Lys167Gln missense_variant 1.0
rpsA 1834043 p.Glu168Gln missense_variant 1.0
rpsA 1834051 c.510G>A synonymous_variant 1.0
rpsA 1834054 c.513C>T synonymous_variant 1.0
clpC1 4039694 c.1011G>C synonymous_variant 1.0
clpC1 4039724 c.981A>G synonymous_variant 1.0
clpC1 4039733 c.972G>A synonymous_variant 1.0
clpC1 4039838 p.Leu289Ile missense_variant 1.0
clpC1 4039847 c.858C>T synonymous_variant 1.0
clpC1 4039850 c.855T>C synonymous_variant 1.0
clpC1 4039859 c.846C>T synonymous_variant 1.0
clpC1 4039875 p.Asn277Arg missense_variant 1.0
clpC1 4039877 c.828C>T synonymous_variant 1.0
ethA 4326569 p.Phe302Tyr missense_variant 1.0
ethA 4326591 p.Leu295Val missense_variant 1.0
ethR 4326598 c.-951T>A upstream_gene_variant 1.0
ethA 4326603 p.Gln291Glu missense_variant 1.0