TB-Profiler result

Run: ERR4818785
Summary

Run ID: ERR4818785

Sample name:

Date: 01-04-2023 15:45:03

Number of reads: 606734

Percentage reads mapped: 77.63

Strain: lineage4.1.2.1

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.31 rifampicin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.13 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.42 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7171 c.-131C>T upstream_gene_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
mshA 576120 p.Ala258Glu missense_variant 0.14
mshA 576394 c.1047G>A synonymous_variant 0.11
mshA 576482 p.Val379Ile missense_variant 0.25
ccsA 619831 c.-60T>G upstream_gene_variant 0.25
ccsA 620029 c.139C>T synonymous_variant 0.14
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoB 761030 c.1224G>C synonymous_variant 0.22
rpoB 761037 c.1231T>C synonymous_variant 0.2
rpoB 761051 c.1245G>C synonymous_variant 0.2
rpoB 761054 c.1248G>C synonymous_variant 0.21
rpoB 761057 c.1251G>C synonymous_variant 0.21
rpoB 761060 c.1254C>G synonymous_variant 0.22
rpoB 761084 c.1278C>A synonymous_variant 0.22
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.22
rpoB 761096 c.1290G>C synonymous_variant 0.22
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.24
rpoB 761102 c.1296A>G synonymous_variant 0.28
rpoB 761132 c.1326G>C synonymous_variant 0.27
rpoB 761133 c.1327T>C synonymous_variant 0.31
rpoB 761147 c.1341C>T synonymous_variant 0.21
rpoB 761150 c.1344A>C synonymous_variant 0.23
rpoB 761159 c.1353G>C synonymous_variant 0.23
rpoB 761165 c.1359G>C synonymous_variant 0.31
rpoB 762026 c.2220G>C synonymous_variant 0.17
rpoB 762051 p.His749Tyr missense_variant 0.15
rpoB 762057 p.Ile751Val missense_variant 0.15
rpoB 762065 c.2259T>C synonymous_variant 0.15
rpoB 762071 p.Asp755Glu missense_variant 0.14
rpoB 762080 c.2274G>C synonymous_variant 0.18
rpoB 762085 p.Ala760Glu missense_variant 0.2
rpoB 762089 c.2283G>A synonymous_variant 0.2
rpoB 762092 c.2286G>A synonymous_variant 0.2
rpoB 762110 c.2304G>C synonymous_variant 0.21
rpoB 762114 p.Ile770Val missense_variant 0.22
rpoB 762122 p.Asp772Glu missense_variant 0.12
rpoB 762125 c.2319G>A synonymous_variant 0.12
rpoB 762126 p.Val774Ser missense_variant 0.12
rpoB 762134 c.2328C>T synonymous_variant 0.25
rpoB 762143 c.2337T>C synonymous_variant 0.25
rpoB 762149 c.2343G>C synonymous_variant 0.25
rpoB 762156 p.Val784Ile missense_variant 0.24
rpoB 762173 c.2367G>A synonymous_variant 0.12
rpoB 762176 c.2370T>C synonymous_variant 0.14
rpoB 762177 p.Arg791Thr missense_variant 0.14
rpoB 762181 p.Asp792Ala missense_variant 0.14
rpoB 762185 c.2379G>C synonymous_variant 0.15
rpoB 762194 c.2388G>C synonymous_variant 0.15
rpoB 762233 c.2427G>C synonymous_variant 0.18
rpoB 762234 p.Pro810Ser missense_variant 0.17
rpoB 762239 c.2433G>A synonymous_variant 0.15
rpoB 762245 c.2439G>C synonymous_variant 0.15
rpoB 762254 c.2448T>C synonymous_variant 0.14
rpoC 763043 c.-327G>C upstream_gene_variant 0.11
rpoC 763053 c.-317T>C upstream_gene_variant 0.11
rpoC 763067 c.-303C>G upstream_gene_variant 0.11
rpoB 763068 p.Asp1088Tyr missense_variant 0.11
rpoB 763077 p.Val1091Thr missense_variant 0.12
rpoC 763103 c.-267G>C upstream_gene_variant 0.11
rpoC 763615 c.246G>C synonymous_variant 0.11
rpoC 763622 p.Ala85Ser missense_variant 0.11
rpoC 763633 c.264T>C synonymous_variant 0.1
rpoC 764485 c.1116G>C synonymous_variant 0.14
rpoC 764491 c.1122G>T synonymous_variant 0.19
rpoC 764503 c.1134G>T synonymous_variant 0.15
rpoC 764509 c.1140G>C synonymous_variant 0.19
rpoC 764521 c.1152T>C synonymous_variant 0.12
rpoC 764536 c.1167G>C synonymous_variant 0.12
rpoC 764566 c.1197C>G synonymous_variant 0.12
rpoC 764581 c.1212T>C synonymous_variant 0.12
rpoC 764582 p.Leu405Met missense_variant 0.14
rpoC 764602 c.1233C>T synonymous_variant 0.12
rpoC 764605 c.1236G>T synonymous_variant 0.13
rpoC 764611 c.1242G>T synonymous_variant 0.14
rpoC 764632 c.1263T>C synonymous_variant 0.11
rpoC 764647 c.1278C>T synonymous_variant 0.1
rpoC 764653 c.1284G>C synonymous_variant 0.1
rpoC 764662 c.1293G>C synonymous_variant 0.1
rpoC 764677 c.1308C>G synonymous_variant 0.22
rpoC 764678 p.Lys437Gln missense_variant 0.22
rpoC 764706 p.Leu446Gln missense_variant 0.24
rpoC 764713 c.1344G>C synonymous_variant 0.29
rpoC 764731 c.1362G>C synonymous_variant 0.22
rpoC 764737 c.1368G>C synonymous_variant 0.22
rpoC 764746 c.1377G>C synonymous_variant 0.21
rpoC 764752 c.1383G>T synonymous_variant 0.17
rpoC 764755 p.Asp462Glu missense_variant 0.17
rpoC 764756 p.Leu463Lys missense_variant 0.17
rpoC 764762 p.His465Tyr missense_variant 0.17
rpoC 764774 p.Ile469Val missense_variant 0.21
rpoC 764780 p.Ser471Ala missense_variant 0.22
rpoC 764793 p.Met475Lys missense_variant 0.21
rpoC 764797 c.1428G>C synonymous_variant 0.21
rpoC 764813 p.Gln482Glu missense_variant 0.2
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 778714 c.-234T>G upstream_gene_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800789 c.-20G>A upstream_gene_variant 0.11
rplC 800815 p.Arg3* stop_gained 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472068 n.223T>C non_coding_transcript_exon_variant 0.25
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.16
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.2
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.59
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.14
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.14
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.54
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.58
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.64
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.85
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.69
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.63
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.26
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.73
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.83
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 1.0
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.67
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.67
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.76
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.74
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.74
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.72
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.69
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.12
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.68
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.12
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.69
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.54
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.56
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.27
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.88
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.14
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.64
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.62
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.38
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.18
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.86
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.82
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.49
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.42
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.5
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.18
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.6
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.36
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.27
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.19
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.47
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.4
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.45
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.42
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.42
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.35
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.53
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.13
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.14
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.7
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.5
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.2
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.7
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.65
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.36
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.14
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.36
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.67
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.56
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.21
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.69
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.18
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.42
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.19
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.38
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.82
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.22
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.26
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.92
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.91
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.9
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.91
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.5
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.51
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.91
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.89
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.91
rrs 1473101 n.1256C>T non_coding_transcript_exon_variant 0.13
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.74
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.93
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.88
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.88
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.21
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.86
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.76
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.68
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.84
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.78
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.72
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.76
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.76
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.78
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.8
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.89
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.72
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.92
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.14
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.14
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.89
rrl 1473384 n.-274A>G upstream_gene_variant 0.55
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.4
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.33
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.33
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.33
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.4
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.5
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.5
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.6
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.5
rrl 1474393 n.736A>G non_coding_transcript_exon_variant 0.5
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.5
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 1.0
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 1.0
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 1.0
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.89
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.89
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 1.0
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 1.0
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.89
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.88
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.6
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.6
rrl 1474634 n.977T>G non_coding_transcript_exon_variant 0.6
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>G non_coding_transcript_exon_variant 0.4
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.43
rrl 1474658 n.1001A>G non_coding_transcript_exon_variant 0.57
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 1.0
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.43
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.57
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.88
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 0.44
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>C non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 1.0
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.5
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.75
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.75
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 1.0
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.67
rrl 1475774 n.2117C>G non_coding_transcript_exon_variant 0.67
rrl 1475783 n.2126T>C non_coding_transcript_exon_variant 0.33
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.43
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.4
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.4
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.4
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.25
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.29
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.5
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.5
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.5
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.5
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.6
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.22
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.5
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.71
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.29
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.29
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.5
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.75
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.25
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.33
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.33
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.33
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.33
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.5
rrl 1476295 n.2638C>A non_coding_transcript_exon_variant 0.5
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.4
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.4
rrl 1476306 n.2649A>G non_coding_transcript_exon_variant 0.4
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 0.4
rrl 1476311 n.2654G>T non_coding_transcript_exon_variant 0.33
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.4
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.81
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.86
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.74
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.7
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.96
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.58
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.64
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.4
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.44
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.22
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.38
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.44
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.22
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.33
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.44
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.44
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.22
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.25
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.25
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.2
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.2
rpsA 1833530 c.-12C>T upstream_gene_variant 0.12
rpsA 1833979 c.438T>C synonymous_variant 0.1
rpsA 1834294 c.753G>C synonymous_variant 0.2
rpsA 1834298 p.Gln253Glu missense_variant 0.21
rpsA 1834306 c.765T>C synonymous_variant 0.16
rpsA 1834307 p.Asp256Gln missense_variant 0.16
rpsA 1834312 c.771G>A synonymous_variant 0.17
rpsA 1834327 c.786G>T synonymous_variant 0.17
rpsA 1834345 c.804C>T synonymous_variant 0.15
rpsA 1834348 c.807T>C synonymous_variant 0.15
rpsA 1834354 c.813G>C synonymous_variant 0.15
rpsA 1834357 c.816T>C synonymous_variant 0.14
rpsA 1834360 c.819G>C synonymous_variant 0.14
rpsA 1834361 c.820T>C synonymous_variant 0.14
rpsA 1834366 c.825A>G synonymous_variant 0.13
rpsA 1834375 c.834G>C synonymous_variant 0.14
rpsA 1834378 c.837T>C synonymous_variant 0.14
rpsA 1834387 c.846C>T synonymous_variant 0.17
rpsA 1834411 c.870T>C synonymous_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169182 c.1431G>T synonymous_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289993 c.-752C>T upstream_gene_variant 0.12
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
eis 2714967 p.Glu122Asp missense_variant 0.22
eis 2715332 p.Val1Met missense_variant 0.11
folC 2746434 p.Gly389Arg missense_variant 0.13
folC 2746864 c.735G>A synonymous_variant 0.11
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449013 c.510C>T synonymous_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
alr 3841546 c.-126C>A upstream_gene_variant 1.0
alr 3841568 c.-148G>A upstream_gene_variant 1.0
alr 3841570 c.-151delA upstream_gene_variant 1.0
alr 3841574 c.-154T>G upstream_gene_variant 1.0
alr 3841578 c.-158G>T upstream_gene_variant 1.0
alr 3841582 c.-162A>G upstream_gene_variant 1.0
alr 3841584 c.-164C>A upstream_gene_variant 1.0
alr 3841589 c.-170delG upstream_gene_variant 1.0
rpoA 3878387 p.Thr41Ala missense_variant 0.11
clpC1 4038501 p.Ile735Thr missense_variant 0.1
embC 4241451 p.Ser530Trp missense_variant 0.13
embC 4242401 p.Arg847Ser missense_variant 0.18
embA 4242628 c.-605C>T upstream_gene_variant 0.2
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4246101 c.2873dupC frameshift_variant 0.11
aftB 4267089 p.Thr583Asn missense_variant 1.0
aftB 4268447 c.390G>T synonymous_variant 0.12
ethA 4326379 c.1095G>C synonymous_variant 0.12
ethR 4327957 p.Leu137Val missense_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338598 c.-77G>T upstream_gene_variant 0.13