TB-Profiler result

Run: SRR5818415

Summary

Run ID: SRR5818415

Sample name:

Date: 04-04-2023 11:24:34

Number of reads: 815520

Percentage reads mapped: 99.55

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoB 760916 c.1110C>T synonymous_variant 0.4
rpoB 760919 c.1113C>T synonymous_variant 0.4
rpoB 760925 c.1119T>C synonymous_variant 0.4
rpoB 760928 c.1122G>C synonymous_variant 0.4
rpoB 760937 c.1131G>A synonymous_variant 0.4
rpoB 760940 c.1134G>C synonymous_variant 0.33
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.33
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.16
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.48
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.17
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.42
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.12
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.3
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.29
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.29
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.3
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.31
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.31
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.31
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.32
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.33
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.34
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.36
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.39
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.44
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.47
tlyA 1917972 c.33A>G synonymous_variant 1.0
eis 2715544 c.-212G>A upstream_gene_variant 0.25
ahpC 2726184 c.-9A>C upstream_gene_variant 0.57
embB 4247646 p.Glu378Ala missense_variant 0.99
ethA 4326764 p.Ala237Val missense_variant 0.28
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407780 c.423G>A synonymous_variant 0.98
gid 4407873 c.330G>T synonymous_variant 1.0