TB-Profiler result

Run: SRR5818421
Summary

Run ID: SRR5818421

Sample name:

Date: 04-04-2023 11:30:43

Number of reads: 762094

Percentage reads mapped: 99.21

Strain: lineage4.9

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.67
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.66
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.57
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.16
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.23
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.26
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.17
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.22
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.2
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.15
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.25
rrs 1472436 n.591G>T non_coding_transcript_exon_variant 0.16
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.16
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.25
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.24
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 0.16
rrs 1472450 n.605A>C non_coding_transcript_exon_variant 0.17
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 0.18
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.19
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.27
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.19
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.19
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.2
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.18
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.17
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.41
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.24
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.45
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.26
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.21
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.2
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.17
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.21
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.19
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.14
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.16
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.14
fabG1 1673770 p.Ala111Pro missense_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
ahpC 2726184 c.-9A>C upstream_gene_variant 0.49
ahpC 2726338 p.Val49Gly missense_variant 0.22
ahpC 2726341 p.Val50Gly missense_variant 0.26