TB-Profiler result

Run: ERR3797074
Summary

Run ID: ERR3797074

Sample name:

Date: 01-04-2023 03:04:38

Number of reads: 20668

Percentage reads mapped: 13.29

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 762065 c.2259T>C synonymous_variant 0.67
rpoB 762083 c.2277T>C synonymous_variant 0.67
rpoB 762086 c.2280G>C synonymous_variant 0.67
rpoB 762101 c.2295C>G synonymous_variant 0.67
rpoB 762114 p.Ile770Val missense_variant 0.67
rpoB 762143 c.2337T>C synonymous_variant 0.67
rpoB 762167 c.2361T>C synonymous_variant 0.5
rpoC 764485 c.1116G>C synonymous_variant 1.0
rpoC 764497 c.1128A>G synonymous_variant 1.0
rpoC 764498 p.Ser377Ala missense_variant 0.67
rpoC 764507 p.Ala380Ser missense_variant 0.67
rpoC 764521 c.1152T>C synonymous_variant 1.0
rpoC 764539 c.1170C>G synonymous_variant 1.0
rpoC 764542 c.1173C>G synonymous_variant 0.67
rpoC 764548 c.1179G>C synonymous_variant 1.0
rpoC 764560 c.1191T>C synonymous_variant 0.67
rpoC 764602 c.1233C>T synonymous_variant 0.67
rpoC 764605 c.1236G>C synonymous_variant 0.67
rpoC 764611 c.1242G>T synonymous_variant 1.0
rpoC 764632 c.1263T>C synonymous_variant 1.0
rpoC 764746 c.1377G>T synonymous_variant 1.0
rpoC 764749 c.1380G>C synonymous_variant 1.0
rpoC 764758 c.1389C>G synonymous_variant 1.0
rpoC 764764 c.1395T>C synonymous_variant 1.0
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 1.0
rpoC 764804 p.Gln479Phe missense_variant 1.0
rpoC 764809 c.1440C>T synonymous_variant 1.0
rpoC 764812 c.1443C>G synonymous_variant 1.0
rpoC 764815 c.1446A>G synonymous_variant 1.0
rpoC 764818 c.1449G>C synonymous_variant 1.0
rpoC 764824 c.1455T>C synonymous_variant 1.0
rpoC 764833 c.1464A>G synonymous_variant 1.0
rpoC 764843 p.Ala492Thr missense_variant 1.0
rpoC 764857 c.1488G>C synonymous_variant 1.0
rpoC 764858 c.1489T>C synonymous_variant 1.0
rpoC 764872 c.1503A>C synonymous_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
fbiC 1304613 c.1683T>C synonymous_variant 1.0
fbiC 1304634 c.1704C>G synonymous_variant 1.0
fbiC 1304640 c.1710A>C synonymous_variant 1.0
fbiC 1304646 c.1716T>C synonymous_variant 1.0
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0
rrs 1472085 n.240C>G non_coding_transcript_exon_variant 1.0
rrs 1472086 n.241T>C non_coding_transcript_exon_variant 1.0
rrs 1472089 n.244C>T non_coding_transcript_exon_variant 1.0
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 1.0
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 1.0
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.96
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 1.0
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 1.0
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 1.0
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472223 n.378C>G non_coding_transcript_exon_variant 1.0
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 1.0
rrs 1472228 n.383G>C non_coding_transcript_exon_variant 1.0
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.98
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.97
rrs 1472277 n.432C>G non_coding_transcript_exon_variant 0.83
rrs 1472282 n.437T>G non_coding_transcript_exon_variant 0.67
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472378 n.533G>T non_coding_transcript_exon_variant 0.75
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.75
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.75
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 1.0
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 1.0
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 1.0
rrs 1472498 n.653C>G non_coding_transcript_exon_variant 1.0
rrs 1472505 n.660G>A non_coding_transcript_exon_variant 1.0
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 1.0
rrs 1472518 n.673G>A non_coding_transcript_exon_variant 1.0
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 1.0
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 1.0
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 1.0
rrs 1472544 n.699C>T non_coding_transcript_exon_variant 1.0
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 1.0
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 1.0
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 1.0
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 1.0
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 1.0
rrs 1472579 n.734G>A non_coding_transcript_exon_variant 1.0
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 1.0
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 1.0
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 1.0
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 1.0
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 1.0
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.96
rrs 1472659 n.814G>A non_coding_transcript_exon_variant 0.96
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 1.0
rrs 1472678 n.834_840delTCCTTGG non_coding_transcript_exon_variant 1.0
rrs 1472687 n.842_843insCC non_coding_transcript_exon_variant 1.0
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.94
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 1.0
rrs 1472698 n.853A>C non_coding_transcript_exon_variant 0.94
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 0.94
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.95
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.95
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.95
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.95
rrs 1472778 n.933C>T non_coding_transcript_exon_variant 1.0
rrs 1472779 n.934G>A non_coding_transcript_exon_variant 1.0
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 1.0
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 1.0
rrl 1474747 n.1090C>T non_coding_transcript_exon_variant 0.75
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.75
rrl 1474758 n.1101G>A non_coding_transcript_exon_variant 0.6
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.6
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.6
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.6
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.75
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.6
rrl 1474801 n.1144G>A non_coding_transcript_exon_variant 0.6
rrl 1474802 n.1145T>A non_coding_transcript_exon_variant 0.6
rrl 1474804 n.1147C>T non_coding_transcript_exon_variant 0.6
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.75
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 1.0
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.75
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.75
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 1.0
rrl 1474828 n.1171G>T non_coding_transcript_exon_variant 0.75
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 1.0
rrl 1474839 n.1182C>T non_coding_transcript_exon_variant 0.8
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.8
rrl 1474869 n.1212G>A non_coding_transcript_exon_variant 0.8
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 1.0
rrl 1475713 n.2056C>T non_coding_transcript_exon_variant 1.0
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 1.0
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 1.0
rrl 1475843 n.2186G>A non_coding_transcript_exon_variant 0.33
rrl 1475853 n.2196C>T non_coding_transcript_exon_variant 0.4
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.4
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.4
rrl 1475874 n.2217C>T non_coding_transcript_exon_variant 0.4
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.67
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.67
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.67
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.75
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.75
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.75
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.75
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.75
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.75
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 1.0
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 1.0
rrl 1476238 n.2581T>C non_coding_transcript_exon_variant 1.0
rrl 1476248 n.2591G>C non_coding_transcript_exon_variant 0.9
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.9
rrl 1476252 n.2595T>C non_coding_transcript_exon_variant 0.9
rrl 1476259 n.2602C>G non_coding_transcript_exon_variant 0.9
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.9
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.92
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.92
rrl 1476298 n.2642_2644delCGA non_coding_transcript_exon_variant 0.92
rrl 1476306 n.2649A>G non_coding_transcript_exon_variant 0.92
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.92
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.92
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.92
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.96
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.94
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.96
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.96
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.96
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.96
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.98
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.99
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.99
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.99
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.99
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.99
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.99
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.98
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.98
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.98
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.99
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.99
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.98
rrl 1476572 n.2915G>T non_coding_transcript_exon_variant 0.98
rrl 1476573 n.2916A>G non_coding_transcript_exon_variant 0.98
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.97
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.94
rrl 1476608 n.2951C>A non_coding_transcript_exon_variant 0.91
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 0.75
rpsA 1834859 p.Ala440Thr missense_variant 1.0