TB-Profiler result

Run: ERR400350
Summary

Run ID: ERR400350

Sample name:

Date: 01-04-2023 03:44:35

Number of reads: 37916

Percentage reads mapped: 1.2

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 764377 c.1008C>G synonymous_variant 0.67
rpoC 764380 c.1011G>C synonymous_variant 0.8
rpoC 764387 c.1018T>C synonymous_variant 0.83
rpoC 764392 c.1023C>T synonymous_variant 0.83
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.83
rpoC 764410 c.1041G>C synonymous_variant 0.83
rpoC 764428 c.1059G>C synonymous_variant 1.0
rpoC 764434 c.1065A>G synonymous_variant 1.0
rpoC 764435 c.1066A>C synonymous_variant 1.0
rpoC 764446 p.Asp359Glu missense_variant 1.0
rpoC 764450 p.Gly361Arg missense_variant 1.0
rpoC 764455 c.1086G>C synonymous_variant 1.0
rpoC 764458 c.1089G>C synonymous_variant 1.0
rpoC 764461 p.Glu364Asp missense_variant 1.0
rpoC 764470 c.1101C>G synonymous_variant 1.0
rpoC 764471 p.Asn368Arg missense_variant 1.0
rpoC 764485 c.1116G>C synonymous_variant 1.0
rpoC 764497 c.1128A>G synonymous_variant 1.0
rpoC 764498 p.Ser377Ala missense_variant 1.0
rpoC 764521 c.1152T>C synonymous_variant 1.0
rpoC 764527 c.1158C>G synonymous_variant 1.0
rpoC 764533 c.1164C>G synonymous_variant 1.0
rpoC 764537 p.Pro390Ala missense_variant 1.0
rpoC 764540 p.Val391Ile missense_variant 1.0
rpoC 764543 c.1176delC frameshift_variant 1.0
rpoC 764549 c.1181_1182delCG frameshift_variant 1.0
rpoC 764553 p.Gly395Ala missense_variant 1.0
rpoC 764557 c.1188_1189insAAG conservative_inframe_insertion 1.0
rpoC 764560 c.1191T>G synonymous_variant 1.0
rpoC 764566 c.1197C>G synonymous_variant 1.0
rpoC 764575 c.1206T>C synonymous_variant 1.0
rpoC 764581 c.1212T>C synonymous_variant 1.0
rpoC 764582 p.Leu405Met missense_variant 1.0
rpoC 764587 c.1218C>G synonymous_variant 1.0
rpoC 764623 c.1254C>G synonymous_variant 1.0
rpoC 764632 c.1263T>C synonymous_variant 1.0
rpoC 764641 c.1272C>T synonymous_variant 1.0
rpoC 764644 c.1275G>C synonymous_variant 1.0
rpoC 764650 c.1281G>T synonymous_variant 1.0
rpoC 764656 c.1287C>G synonymous_variant 1.0
rpoC 764665 c.1296C>G synonymous_variant 1.0
rpoC 764668 c.1299C>T synonymous_variant 1.0
rpoC 764671 c.1302G>C synonymous_variant 1.0
rpoC 764672 p.Gln435Glu missense_variant 1.0
rpoC 764677 c.1308C>G synonymous_variant 1.0
rpoC 764695 c.1326T>C synonymous_variant 1.0
rpoC 764701 c.1332C>G synonymous_variant 1.0
rpoC 764705 p.Leu446Lys missense_variant 1.0
rpoC 764731 c.1362G>C synonymous_variant 1.0
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.67
rrs 1472603 n.758A>C non_coding_transcript_exon_variant 0.67
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.67
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 1.0
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 1.0
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 1.0
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 1.0
rrs 1472970 n.1125C>T non_coding_transcript_exon_variant 1.0
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0
rrs 1472974 n.1129A>C non_coding_transcript_exon_variant 1.0
rrs 1472975 n.1130T>G non_coding_transcript_exon_variant 1.0
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 1.0
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 1.0
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 1.0
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 1.0
rrs 1472993 n.1148G>A non_coding_transcript_exon_variant 1.0
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 1.0
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 1.0
rrs 1473008 n.1163C>G non_coding_transcript_exon_variant 1.0
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 1.0
rrs 1473038 n.1193A>C non_coding_transcript_exon_variant 1.0
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 1.0
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 1.0
rrs 1473054 n.1209C>G non_coding_transcript_exon_variant 1.0
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 1.0
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 1.0
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 1.0
rrl 1476266 n.2609G>A non_coding_transcript_exon_variant 1.0
rrl 1476279 n.2622G>C non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 1.0
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 1.0
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 1.0
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 1.0
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 1.0
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 1.0
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 1.0
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 1.0
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 1.0
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 1.0
rrl 1476339 n.2682G>A non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 1.0
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 1.0
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 1.0
rrl 1476417 n.2760T>C non_coding_transcript_exon_variant 1.0
rrl 1476443 n.2786G>C non_coding_transcript_exon_variant 1.0
rrl 1476455 n.2798C>G non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 1.0
rrl 1476516 n.2859G>A non_coding_transcript_exon_variant 1.0
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 1.0
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 1.0
rrl 1476521 n.2864C>T non_coding_transcript_exon_variant 1.0
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 1.0
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 1.0
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 1.0
rrl 1476532 n.2876_2877insCG non_coding_transcript_exon_variant 1.0
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 1.0
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 1.0
rrl 1476588 n.2931A>G non_coding_transcript_exon_variant 1.0
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 1.0
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 1.0
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 1.0
rrl 1476611 n.2954T>C non_coding_transcript_exon_variant 1.0