TB-Profiler result

Run: ERR6866821
Summary

Run ID: ERR6866821

Sample name:

Date: 02-04-2023 03:38:42

Number of reads: 1536405

Percentage reads mapped: 77.43

Strain: lineage4.1.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoB 760555 p.Glu250Gly missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302920 c.-11G>A upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.25
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.29
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.29
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.24
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.28
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.31
rrs 1472518 n.673G>C non_coding_transcript_exon_variant 0.31
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.36
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.37
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.38
rrs 1472544 n.699C>G non_coding_transcript_exon_variant 0.38
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.38
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.39
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.39
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.39
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.41
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.41
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.48
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.59
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.69
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.67
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.67
rrs 1472669 n.824_825insTAG non_coding_transcript_exon_variant 0.62
rrs 1472676 n.832_840delCTTCCTTGG non_coding_transcript_exon_variant 0.62
rrs 1472689 n.844C>G non_coding_transcript_exon_variant 0.59
rrs 1472690 n.845_846insCCGTA non_coding_transcript_exon_variant 0.62
rrs 1472697 n.852T>A non_coding_transcript_exon_variant 0.65
rrs 1472700 n.855C>T non_coding_transcript_exon_variant 0.65
rrs 1472705 n.860G>A non_coding_transcript_exon_variant 0.62
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.62
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.59
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.57
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.44
rrs 1472779 n.934G>A non_coding_transcript_exon_variant 0.18
rrs 1472953 n.1108_1109insA non_coding_transcript_exon_variant 0.27
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.27
rrs 1472958 n.1114delT non_coding_transcript_exon_variant 0.27
rrs 1472969 n.1125_1126delCG non_coding_transcript_exon_variant 0.27
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.23
rrs 1472975 n.1130T>A non_coding_transcript_exon_variant 0.23
rrs 1472977 n.1132G>T non_coding_transcript_exon_variant 0.21
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.2
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.25
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.24
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.24
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.24
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.24
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.13
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.13
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.18
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.18
rrl 1474236 n.579G>A non_coding_transcript_exon_variant 0.18
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.2
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.2
rrl 1474482 n.825G>T non_coding_transcript_exon_variant 0.22
rrl 1474494 n.837C>G non_coding_transcript_exon_variant 0.22
rrl 1474495 n.838G>T non_coding_transcript_exon_variant 0.22
rrl 1474503 n.846G>C non_coding_transcript_exon_variant 0.22
rrl 1474508 n.851C>A non_coding_transcript_exon_variant 0.22
rrl 1474509 n.852G>C non_coding_transcript_exon_variant 0.22
rrl 1474527 n.870T>G non_coding_transcript_exon_variant 0.25
rrl 1474528 n.871T>C non_coding_transcript_exon_variant 0.25
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.25
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.29
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.29
rrl 1474542 n.885A>C non_coding_transcript_exon_variant 0.33
rrl 1474552 n.895C>G non_coding_transcript_exon_variant 0.33
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.22
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.3
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.27
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.27
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.22
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.22
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.18
rrl 1476135 n.2478T>C non_coding_transcript_exon_variant 0.14
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.25
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.4
rrl 1476164 n.2507A>C non_coding_transcript_exon_variant 0.43
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.46
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.46
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.46
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.46
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.43
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.43
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.43
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.4
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.4
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.4
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.4
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.4
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.47
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.53
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 0.62
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.63
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.67
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.64
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.6
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.6
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.59
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.59
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.57
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.57
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.6
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.6
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.7
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.73
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.76
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.78
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.79
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.73
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.75
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.78
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.78
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.75
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.68
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.66
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.63
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.63
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.63
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.62
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.59
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.59
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.59
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.59
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.58
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.54
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.51
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.5
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.51
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.46
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.32
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.24
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.2
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
folC 2746277 p.Asp441Gly missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.98
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0