TB-Profiler result

Run: SRR5818463
Summary

Run ID: SRR5818463

Sample name:

Date: 04-04-2023 11:36:31

Number of reads: 696165

Percentage reads mapped: 99.85

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 760872 p.Glu356* stop_gained 0.17
rpoB 760931 c.1125C>T synonymous_variant 0.14
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.43
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.55
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.44
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.24
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.14
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.14
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.41
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.41
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.39
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.38
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.4
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.36
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.36
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.36
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.39
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.44
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.45
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.44
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.52
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.59
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.15
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.19
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.19
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.16
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.15
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.19
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.16
fabG1 1673770 p.Ala111Pro missense_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
ahpC 2726184 c.-9A>C upstream_gene_variant 0.36
ahpC 2726341 p.Val50Gly missense_variant 0.28