TB-Profiler result

Run: ERR2179816
Summary

Run ID: ERR2179816

Sample name:

Date: 15-08-2022 11:57:02

Number of reads: 2778139

Percentage reads mapped: 58.06

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5078 c.-162_-161insG upstream_gene_variant 0.1
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8147 p.Asn282Lys missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304501 p.Ala524Gly missense_variant 1.0
fbiC 1305357 c.2427C>G synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.15
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.15
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.16
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.2
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.2
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.24
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.23
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.24
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.2
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.12
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.11
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.11
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.11
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.11
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 0.11
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.17
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.19
rrs 1472697 n.852T>A non_coding_transcript_exon_variant 0.11
rrs 1472700 n.855C>T non_coding_transcript_exon_variant 0.16
rrs 1472705 n.860G>A non_coding_transcript_exon_variant 0.19
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.21
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.22
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.44
rrs 1472779 n.934G>A non_coding_transcript_exon_variant 0.47
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.45
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.34
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.29
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.17
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.17
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.17
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.17
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.17
rrs 1473080 n.1235C>A non_coding_transcript_exon_variant 0.14
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.14
rrs 1473094 n.1249T>A non_coding_transcript_exon_variant 0.13
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.22
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.3
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.3
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.3
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.31
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.43
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.49
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.48
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.37
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.25
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.23
rrl 1474913 n.1256T>A non_coding_transcript_exon_variant 0.23
rrl 1474920 n.1263G>C non_coding_transcript_exon_variant 0.16
rrl 1475106 n.1449G>A non_coding_transcript_exon_variant 1.0
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 0.1
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.12
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.11
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.12
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.12
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.13
rrl 1476251 n.2594T>A non_coding_transcript_exon_variant 0.15
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.21
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.25
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.42
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.44
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.43
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.43
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.43
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.45
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.46
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.47
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.59
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.57
rrl 1476353 n.2696G>A non_coding_transcript_exon_variant 0.52
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.52
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.51
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.53
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.54
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.6
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.56
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.56
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.47
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.44
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.29
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.23
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.21
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.17
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.17
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.17
fabG1 1674127 p.Ser230Gly missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918672 p.Thr245Ala missense_variant 1.0
PPE35 2168742 p.Gly624Asp missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3475122 c.1116G>A synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4268904 c.-68C>T upstream_gene_variant 1.0
ethA 4327376 p.Ala33Gly missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0