TB-Profiler result

Run: SRR13861336
Summary

Run ID: SRR13861336

Sample name:

Date: 03-04-2023 09:29:17

Number of reads: 1526929

Percentage reads mapped: 38.21

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.37 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
fgd1 490955 p.Met58Arg missense_variant 1.0
mmpS5 779639 c.-735dupG upstream_gene_variant 1.0
fbiC 1304529 c.1599T>C synonymous_variant 1.0
Rv1258c 1406845 p.Ala166Pro missense_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.14
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.2
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 0.15
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.22
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.22
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.27
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.25
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.25
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.25
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.25
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.25
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.26
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.26
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.26
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.26
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.29
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.29
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.28
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.27
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.19
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.14
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.13
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.28
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.28
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.28
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.28
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.28
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.29
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.28
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.27
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.27
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.27
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.27
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.27
rrs 1472596 n.751G>T non_coding_transcript_exon_variant 0.28
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.28
rrs 1472614 n.769G>T non_coding_transcript_exon_variant 0.35
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.38
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.37
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.32
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.32
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.32
rrs 1472669 n.824_825insTAGG non_coding_transcript_exon_variant 0.32
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.33
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.33
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.34
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.34
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.35
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.34
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.13
rrs 1473282 n.1437C>G non_coding_transcript_exon_variant 0.11
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.28
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.34
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.44
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.45
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.45
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.42
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.41
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.41
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.42
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.42
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.42
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.42
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.42
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.43
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.43
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.45
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.45
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.47
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.54
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.64
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.7
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.7
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.61
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.65
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.44
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.63
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.6
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.55
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.64
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.64
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.54
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.43
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.31
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.3
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.29
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.3
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.3
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.31
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.28
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.28
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.28
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.3
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.29
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.28
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.29
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.29
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.27
inhA 1674607 p.Pro136Ser missense_variant 1.0
inhA 1674778 p.Pro193Ala missense_variant 1.0
PPE35 2169081 p.Leu511Ser missense_variant 1.0
PPE35 2169202 p.Ser471Pro missense_variant 1.0
Rv1979c 2222091 c.1074G>T synonymous_variant 1.0
Rv1979c 2223306 c.-142T>A upstream_gene_variant 1.0
pncA 2289228 p.Ile5Asn missense_variant 1.0
kasA 2518176 p.Ala21Gly missense_variant 1.0
eis 2714755 p.Pro193Gln missense_variant 1.0
ahpC 2726324 c.132A>G synonymous_variant 1.0
ahpC 2726362 p.Phe57Ser missense_variant 1.0
pepQ 2859580 p.Leu280Arg missense_variant 1.0
pepQ 2859999 c.420G>T synonymous_variant 1.0
thyX 3067940 c.6C>G synonymous_variant 1.0
thyA 3074620 c.-149C>A upstream_gene_variant 1.0
fprA 3473861 c.-146T>G upstream_gene_variant 1.0
fprA 3474953 p.Gln316Arg missense_variant 1.0
ddn 3986889 p.Phe16Val missense_variant 1.0
embC 4242041 p.Met727Leu missense_variant 1.0
embA 4244723 p.Gln497His missense_variant 1.0
aftB 4267979 c.858G>C synonymous_variant 1.0