TB-Profiler result

Run: ERR779680
Summary

Run ID: ERR779680

Sample name:

Date: 02-04-2023 05:51:38

Number of reads: 2006503

Percentage reads mapped: 61.63

Strain: lineage4.3.4.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.4 Euro-American (LAM) LAM RD174 1.0
lineage4.3.4.2 Euro-American (LAM) LAM1;LAM4;LAM11 RD174 1.0
lineage4.3.4.2.1 Euro-American (LAM) LAM11 RD174 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6140 p.Val301Leu missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471896 n.51T>C non_coding_transcript_exon_variant 0.1
rrs 1472085 n.240C>G non_coding_transcript_exon_variant 0.13
rrs 1472086 n.241T>C non_coding_transcript_exon_variant 0.13
rrs 1472089 n.244C>T non_coding_transcript_exon_variant 0.2
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.33
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.35
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.37
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.38
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.42
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.55
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.55
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.66
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.68
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.67
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.72
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.66
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.65
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.65
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.54
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.44
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.38
rrs 1472378 n.533G>T non_coding_transcript_exon_variant 0.15
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.15
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.16
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.19
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.2
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.19
rrs 1472544 n.699C>T non_coding_transcript_exon_variant 0.2
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.19
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.46
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.51
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.51
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.52
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.52
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.5
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.51
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.46
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.24
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.33
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.67
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.69
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.78
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.8
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.8
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.78
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.78
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.7
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.25
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.12
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.11
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.14
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.15
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.11
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.12
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.2
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.21
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.24
rrl 1474824 n.1167A>C non_coding_transcript_exon_variant 0.24
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.29
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.32
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.37
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.4
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.39
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.4
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.46
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.35
rrl 1474903 n.1246T>G non_coding_transcript_exon_variant 0.33
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.34
rrl 1474913 n.1256T>A non_coding_transcript_exon_variant 0.3
rrl 1474920 n.1263G>T non_coding_transcript_exon_variant 0.32
rrl 1474928 n.1271C>A non_coding_transcript_exon_variant 0.12
rrl 1475777 n.2120A>C non_coding_transcript_exon_variant 0.13
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 0.31
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.42
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.43
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.46
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.46
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.45
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.44
rrl 1475877 n.2220C>T non_coding_transcript_exon_variant 0.12
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.12
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.2
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.14
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.14
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.14
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.14
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.14
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.13
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.14
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.14
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.14
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.15
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.17
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.26
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.3
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.27
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.21
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.18
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.15
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.5
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.66
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.69
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.74
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.75
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.76
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.85
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.85
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.83
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.83
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.77
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.73
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.45
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.28
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.21
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.21
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.21
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.21
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.21
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.22
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.21
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.21
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.21
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.22
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.15
inhA 1674952 p.Pro251Ala missense_variant 0.19
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169320 p.Leu431Phe missense_variant 0.17
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.22
ribD 2987307 p.Ala157Pro missense_variant 0.19
thyA 3073806 c.666C>G synonymous_variant 0.3
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
fbiB 3642772 p.Asp413Ala missense_variant 0.38
alr 3840719 c.702A>G synonymous_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4038857 c.1848C>A synonymous_variant 0.3
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242822 p.Val987Gly missense_variant 0.27
ubiA 4269529 p.Ala102Gly missense_variant 0.19
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0