TB-Profiler result

Run: SRR5818396
Summary

Run ID: SRR5818396

Sample name:

Date: 04-04-2023 11:21:21

Number of reads: 1183136

Percentage reads mapped: 99.8

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.45 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
rplC 801093 c.285_286insT frameshift_variant 0.4
rrs 1471937 n.92C>T non_coding_transcript_exon_variant 0.12
rrs 1472119 n.274G>A non_coding_transcript_exon_variant 0.22
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.84
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.84
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.74
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.16
rrs 1472332 n.487A>G non_coding_transcript_exon_variant 0.16
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.16
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.23
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.35
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.34
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.34
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.24
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.18
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.32
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.32
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.25
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.25
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.33
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.28
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.28
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.27
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.3
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.36
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.29
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.29
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.54
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.24
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.59
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.34
rrs 1472571 n.726G>T non_coding_transcript_exon_variant 0.3
rrs 1472579 n.734G>A non_coding_transcript_exon_variant 0.2
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.68
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.56
rrs 1472582 n.737G>T non_coding_transcript_exon_variant 0.2
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.47
rrs 1472585 n.740A>C non_coding_transcript_exon_variant 0.18
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.51
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.42
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.21
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.26
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.56
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.62
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.55
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.56
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.26
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.13
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.14
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.13
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.14
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.15
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.16
fabG1 1673770 p.Ala111Pro missense_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
eis 2715155 p.Gly60Arg missense_variant 1.0
eis 2715545 c.-213C>G upstream_gene_variant 0.67
ahpC 2726184 c.-9A>C upstream_gene_variant 0.48
aftB 4267455 p.Asp461Gly missense_variant 1.0
ethA 4326764 p.Ala237Val missense_variant 0.21