TB-Profiler result

Run: SRR8692782
Summary

Run ID: SRR8692782

Sample name:

Date: 13-08-2023 20:38:53

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.9

Drug-resistance: Other

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rplC 801268 p.Cys154Arg missense_variant 0.75 linezolid
panD 4043931 p.Met117Ile missense_variant 0.12 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5189 c.-51C>A upstream_gene_variant 0.17
gyrB 5803 c.564A>G synonymous_variant 0.12
gyrB 5806 c.567C>G synonymous_variant 0.14
gyrB 5807 p.Val190Ile missense_variant 0.14
gyrB 5818 c.579G>A synonymous_variant 0.13
gyrB 5824 c.585A>G synonymous_variant 0.13
gyrB 5833 c.594G>C synonymous_variant 0.2
gyrB 5839 c.600C>G synonymous_variant 0.18
gyrB 5848 c.609G>C synonymous_variant 0.15
gyrB 5858 p.Asn207Glu missense_variant 0.17
gyrB 5873 c.634_636delAGGinsCGC synonymous_variant 0.2
gyrB 5878 c.639G>C synonymous_variant 0.2
gyrB 5879 p.Thr214Ala missense_variant 0.2
gyrB 5883 p.Gln215Pro missense_variant 0.2
gyrB 5887 p.Asp216Glu missense_variant 0.2
gyrB 5889 p.Glu217Ala missense_variant 0.2
gyrB 5899 c.660C>T synonymous_variant 0.22
gyrB 5902 c.663A>G synonymous_variant 0.2
gyrB 5915 p.Val226His missense_variant 0.18
gyrB 6152 p.Ala305Ser missense_variant 0.13
gyrA 7362 p.Glu21Gln missense_variant 0.15
gyrA 7593 p.Arg98Ser missense_variant 0.17
gyrA 7965 p.Arg222Trp missense_variant 0.14
gyrA 8353 p.Gly351Val missense_variant 0.2
gyrA 8676 p.Glu459* stop_gained 0.17
gyrA 9267 p.Asn656Asp missense_variant 0.1
mshA 575998 c.651C>G synonymous_variant 0.15
mshA 576438 p.Ala364Glu missense_variant 0.22
rpoB 760047 p.Glu81* stop_gained 0.14
rpoB 760143 p.Val113Ile missense_variant 0.22
rpoB 760532 c.726T>C synonymous_variant 0.11
rpoB 760535 c.729C>G synonymous_variant 0.11
rpoB 760541 c.735G>C synonymous_variant 0.12
rpoB 760547 c.741G>C synonymous_variant 0.12
rpoB 760561 c.757_758delCG frameshift_variant 0.14
rpoB 760567 p.Ser254Trp missense_variant 0.2
rpoB 760568 c.762_763insGC frameshift_variant 0.14
rpoB 760591 p.Val262Ala missense_variant 0.25
rpoB 760601 c.795C>T synonymous_variant 0.17
rpoB 760611 c.805T>C synonymous_variant 0.15
rpoB 760625 c.819C>G synonymous_variant 0.15
rpoB 760634 c.828T>C synonymous_variant 0.15
rpoB 760677 p.Glu291* stop_gained 0.18
rpoB 761009 p.Gln401His missense_variant 0.14
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.13
rpoB 761102 c.1296A>G synonymous_variant 0.13
rpoB 761132 c.1326G>T synonymous_variant 0.14
rpoB 761133 c.1327T>C synonymous_variant 0.14
rpoB 761147 c.1341C>T synonymous_variant 0.17
rpoB 761150 c.1344A>T synonymous_variant 0.15
rpoB 761165 c.1359G>C synonymous_variant 0.14
rpoB 761180 c.1374A>C synonymous_variant 0.17
rpoB 761189 c.1383T>C synonymous_variant 0.18
rpoB 761195 c.1389G>C synonymous_variant 0.2
rpoB 761198 c.1392G>T synonymous_variant 0.2
rpoB 761217 p.Pro471Ser missense_variant 0.2
rpoB 761302 p.Arg499Leu missense_variant 0.18
rpoB 761705 c.1899C>T synonymous_variant 0.13
rpoB 761712 p.Val636Ile missense_variant 0.13
rpoB 761723 p.Glu639Asp missense_variant 0.14
rpoB 761724 p.Glu640Lys missense_variant 0.14
rpoB 761728 p.Ser641Thr missense_variant 0.13
rpoB 761732 c.1926C>T synonymous_variant 0.12
rpoB 761747 c.1941G>C synonymous_variant 0.12
rpoB 761765 c.1959T>C synonymous_variant 0.11
rpoB 761772 p.His656Ala missense_variant 0.12
rpoB 761778 p.Asn658Asp missense_variant 0.12
rpoB 761785 p.Thr660Ser missense_variant 0.12
rpoB 761791 p.Arg662Gln missense_variant 0.12
rpoB 761999 c.2193G>C synonymous_variant 0.14
rpoB 762002 c.2196C>G synonymous_variant 0.14
rpoB 762047 c.2241G>A synonymous_variant 0.21
rpoB 762053 c.2247T>C synonymous_variant 0.22
rpoB 762065 c.2259T>C synonymous_variant 0.21
rpoB 762083 c.2277T>C synonymous_variant 0.21
rpoB 762086 c.2280G>C synonymous_variant 0.21
rpoB 762101 c.2295C>G synonymous_variant 0.22
rpoB 762114 p.Ile770Val missense_variant 0.25
rpoB 762122 c.2316C>T synonymous_variant 0.19
rpoB 762131 c.2325C>G synonymous_variant 0.2
rpoB 762137 c.2331C>T synonymous_variant 0.14
rpoB 762176 c.2370T>C synonymous_variant 0.18
rpoC 762959 c.-411G>C upstream_gene_variant 0.2
rpoC 762962 c.-408C>T upstream_gene_variant 0.25
rpoC 762983 c.-387C>T upstream_gene_variant 0.21
rpoC 762989 c.-381G>A upstream_gene_variant 0.16
rpoC 762995 c.-375G>T upstream_gene_variant 0.15
rpoC 763004 c.-366G>A upstream_gene_variant 0.14
rpoC 763007 c.-363C>T upstream_gene_variant 0.15
rpoC 763028 c.-342T>C upstream_gene_variant 0.14
rpoC 763031 c.-339T>C upstream_gene_variant 0.14
rpoC 763049 c.-321G>A upstream_gene_variant 0.16
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 0.15
rpoC 763070 c.-300T>C upstream_gene_variant 0.15
rpoC 763076 c.-294C>G upstream_gene_variant 0.15
rpoC 763079 c.-291C>G upstream_gene_variant 0.15
rpoC 763082 c.-288C>T upstream_gene_variant 0.16
rpoC 763085 c.-285C>G upstream_gene_variant 0.16
rpoC 763103 c.-267G>C upstream_gene_variant 0.14
rpoC 763375 c.6C>A synonymous_variant 0.14
rpoC 763423 p.Glu18Asp missense_variant 0.11
rpoC 763430 c.61_63delAGGinsCGC synonymous_variant 0.11
rpoC 763435 p.Gln22His missense_variant 0.11
rpoC 763443 p.Tyr25Phe missense_variant 0.12
rpoC 763456 c.87A>G synonymous_variant 0.11
rpoC 764632 c.1263T>C synonymous_variant 0.11
rpoC 765406 c.2037G>T synonymous_variant 0.24
rpoC 765731 p.Ala788Ser missense_variant 0.14
rpoC 765772 c.2403C>G synonymous_variant 0.15
rpoC 765778 c.2409C>G synonymous_variant 0.15
rpoC 765779 p.Asp804Lys missense_variant 0.15
rpoC 765800 p.Phe811Leu missense_variant 0.13
rpoC 765811 c.2442T>C synonymous_variant 0.14
rpoC 765814 c.2445A>C synonymous_variant 0.14
rpoC 765820 c.2451G>C synonymous_variant 0.14
rpoC 765823 c.2454C>G synonymous_variant 0.14
rpoC 765826 c.2457T>C synonymous_variant 0.14
rpoC 765835 c.2466C>T synonymous_variant 0.13
rpoC 765861 p.Phe831Tyr missense_variant 0.2
rpoC 765875 p.Val836Ile missense_variant 0.15
rpoC 765886 c.2517C>G synonymous_variant 0.13
rpoC 765892 c.2523T>C synonymous_variant 0.14
rpoC 766246 p.Gln959His missense_variant 0.13
rpoC 766444 c.3075C>T synonymous_variant 0.17
rpoC 767002 c.3633G>C synonymous_variant 0.12
rpoC 767011 c.3642G>A synonymous_variant 0.12
rpoC 767014 c.3645G>C synonymous_variant 0.2
rpoC 767023 c.3654C>T synonymous_variant 0.27
rpoC 767035 c.3666G>C synonymous_variant 0.27
rpoC 767098 c.3729T>C synonymous_variant 0.33
rpoC 767104 c.3735C>G synonymous_variant 0.33
rpoC 767106 p.Asn1246Met missense_variant 0.36
rpoC 767119 c.3750A>G synonymous_variant 0.35
rpoC 767155 c.3786C>G synonymous_variant 0.29
rpoC 767162 p.Asn1265Ala missense_variant 0.27
rpoC 767173 c.3804C>G synonymous_variant 0.29
rpoC 767174 p.Asn1269Asp missense_variant 0.29
rpoC 767180 p.Ala1271Gln missense_variant 0.29
rpoC 767185 c.3816G>C synonymous_variant 0.29
rpoC 767186 p.Gln1273Asn missense_variant 0.29
rpoC 767191 c.3822C>G synonymous_variant 0.31
rpoC 767197 c.3828G>A synonymous_variant 0.27
rpoC 767221 c.3852C>G synonymous_variant 0.29
rpoC 767230 c.3861G>C synonymous_variant 0.23
rpoC 767233 c.3864T>C synonymous_variant 0.23
rpoC 767237 p.Asp1290Tyr missense_variant 0.17
mmpL5 776981 c.1500G>T synonymous_variant 0.12
mmpL5 777696 p.Ala262Val missense_variant 0.15
mmpL5 777765 p.Gly239Val missense_variant 0.21
mmpR5 778451 c.-539C>T upstream_gene_variant 0.17
mmpS5 778872 p.Leu12Met missense_variant 0.14
mmpL5 779298 c.-818G>A upstream_gene_variant 0.15
mmpR5 779305 p.Glu106Lys missense_variant 0.15
rpsL 781652 c.93T>C synonymous_variant 0.12
rpsL 781658 c.99A>G synonymous_variant 0.11
rpsL 781682 c.123T>C synonymous_variant 0.11
rplC 800639 c.-170C>A upstream_gene_variant 0.17
fbiC 1303039 p.Val37Phe missense_variant 0.12
fbiC 1303306 p.Asp126Tyr missense_variant 0.2
fbiC 1304191 p.Ala421Thr missense_variant 0.23
fbiC 1304518 p.Ala530Thr missense_variant 0.17
fbiC 1304551 p.Gly541Cys missense_variant 0.22
fbiC 1304613 c.1683T>C synonymous_variant 0.15
fbiC 1304634 c.1704C>G synonymous_variant 0.17
fbiC 1304639 p.Arg570Leu missense_variant 0.14
fbiC 1304646 c.1716T>C synonymous_variant 0.12
fbiC 1304658 c.1728C>G synonymous_variant 0.11
fbiC 1304672 p.Val581Ala missense_variant 0.11
fbiC 1304676 c.1746A>C synonymous_variant 0.11
fbiC 1304703 c.1773C>G synonymous_variant 0.12
fbiC 1304715 c.1785G>C synonymous_variant 0.15
fbiC 1304724 c.1794A>G synonymous_variant 0.15
fbiC 1304727 c.1797A>C synonymous_variant 0.15
fbiC 1304742 c.1812T>C synonymous_variant 0.17
fbiC 1304748 c.1818T>C synonymous_variant 0.14
fbiC 1304799 c.1869G>C synonymous_variant 0.11
fbiC 1304808 c.1878C>G synonymous_variant 0.11
fbiC 1304817 c.1887T>C synonymous_variant 0.12
fbiC 1304832 c.1902C>G synonymous_variant 0.11
fbiC 1305018 c.2088C>A synonymous_variant 0.17
Rv1258c 1406406 p.Pro312Gln missense_variant 0.14
Rv1258c 1406528 c.813C>A synonymous_variant 0.14
Rv1258c 1406598 p.Pro248Leu missense_variant 0.18
Rv1258c 1406686 p.Val219Ile missense_variant 0.9
Rv1258c 1407197 c.144C>A synonymous_variant 0.15
Rv1258c 1407270 p.Gly24Asp missense_variant 0.13
embR 1416814 c.534G>A synonymous_variant 0.15
atpE 1461000 c.-45C>A upstream_gene_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.18
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.18
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.25
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.27
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.17
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.45
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.45
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.45
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.45
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.42
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.42
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.42
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.42
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.36
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.3
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.33
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.33
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.33
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.33
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.33
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.38
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.44
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.18
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.17
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.17
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.42
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.25
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.14
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.3
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.3
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.32
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.33
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.33
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.33
rrl 1473816 n.159C>G non_coding_transcript_exon_variant 0.33
rrl 1473828 n.171G>C non_coding_transcript_exon_variant 0.4
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.4
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.4
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.4
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.4
rrl 1474066 n.409G>T non_coding_transcript_exon_variant 0.18
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.57
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.5
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.4
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.29
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.23
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.23
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.21
rrl 1474709 n.1053delT non_coding_transcript_exon_variant 0.24
rrl 1474714 n.1058delT non_coding_transcript_exon_variant 0.25
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.19
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.18
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.19
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.23
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.27
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.23
rrl 1475343 n.1686A>G non_coding_transcript_exon_variant 0.27
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.27
rrl 1475358 n.1701T>C non_coding_transcript_exon_variant 0.27
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.27
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.3
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.38
rrl 1475381 n.1724G>T non_coding_transcript_exon_variant 0.38
rrl 1475382 n.1725A>C non_coding_transcript_exon_variant 0.38
rrl 1475395 n.1738T>G non_coding_transcript_exon_variant 0.4
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 0.4
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.4
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.4
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.45
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.5
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.56
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.5
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.5
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.5
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.57
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.44
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.4
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.38
rrl 1475574 n.1917C>A non_coding_transcript_exon_variant 0.2
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.23
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.48
rrl 1475759 n.2102C>T non_coding_transcript_exon_variant 0.48
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.48
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.48
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.5
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.5
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.52
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.22
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.25
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.24
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.25
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.26
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.26
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.25
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.28
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.28
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.26
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.26
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.26
rrl 1476085 n.2428G>T non_coding_transcript_exon_variant 0.18
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.17
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.22
rrl 1476132 n.2475G>T non_coding_transcript_exon_variant 0.2
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.56
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.56
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.6
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.7
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.8
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.8
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.7
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.64
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.64
rrl 1476347 n.2690C>T non_coding_transcript_exon_variant 0.18
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.41
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.46
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.45
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.5
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.5
fabG1 1673186 c.-254C>T upstream_gene_variant 0.13
fabG1 1673201 c.-239G>T upstream_gene_variant 0.14
fabG1 1673389 c.-51C>G upstream_gene_variant 0.15
fabG1 1673401 c.-39G>T upstream_gene_variant 0.15
fabG1 1673421 c.-19G>T upstream_gene_variant 0.17
inhA 1674726 c.525G>T synonymous_variant 0.14
inhA 1674909 c.708G>C synonymous_variant 0.11
rpsA 1833676 c.135A>G synonymous_variant 0.14
rpsA 1833697 c.156C>G synonymous_variant 0.14
rpsA 1833727 c.186G>A synonymous_variant 0.18
rpsA 1833734 p.Ala65Ser missense_variant 0.19
rpsA 1833745 c.204G>C synonymous_variant 0.21
rpsA 1833760 c.219C>T synonymous_variant 0.22
rpsA 1833787 c.246C>G synonymous_variant 0.22
rpsA 1833790 c.249T>C synonymous_variant 0.22
rpsA 1833793 c.252C>T synonymous_variant 0.22
rpsA 1833802 c.261A>G synonymous_variant 0.23
rpsA 1833808 c.267G>C synonymous_variant 0.23
rpsA 1833811 c.270G>T synonymous_variant 0.24
rpsA 1833829 c.288A>G synonymous_variant 0.26
rpsA 1833832 c.291G>A synonymous_variant 0.26
rpsA 1833838 c.297G>C synonymous_variant 0.26
rpsA 1833841 c.300C>G synonymous_variant 0.25
rpsA 1833847 c.306C>G synonymous_variant 0.23
rpsA 1833856 c.315A>G synonymous_variant 0.22
rpsA 1833862 c.321G>T synonymous_variant 0.22
rpsA 1833892 c.351G>A synonymous_variant 0.16
rpsA 1833894 p.Ala118Glu missense_variant 0.17
rpsA 1833970 c.429G>C synonymous_variant 0.12
rpsA 1834177 c.636A>C synonymous_variant 0.11
rpsA 1834451 c.910T>C synonymous_variant 0.12
rpsA 1834456 c.915T>G synonymous_variant 0.12
rpsA 1834513 c.972C>G synonymous_variant 0.13
rpsA 1834520 p.Ala327Ser missense_variant 0.12
rpsA 1834528 c.987T>C synonymous_variant 0.12
rpsA 1834540 c.999G>C synonymous_variant 0.15
tlyA 1918518 c.579C>A synonymous_variant 0.13
ndh 2101727 p.Arg439Leu missense_variant 0.2
ndh 2102083 c.960G>T synonymous_variant 0.15
ndh 2102122 c.921C>A synonymous_variant 0.13
katG 2154081 c.2031C>A synonymous_variant 0.25
katG 2154131 p.Leu661Met missense_variant 0.22
katG 2154132 p.Asn660Lys missense_variant 0.22
PPE35 2167903 p.Gly904Ser missense_variant 0.17
PPE35 2168814 c.1798dupA frameshift_variant 0.22
PPE35 2168920 p.Val565Phe missense_variant 0.12
PPE35 2168984 c.1629G>T synonymous_variant 0.14
Rv1979c 2222163 c.1002G>T synonymous_variant 0.13
Rv1979c 2222298 c.867G>T synonymous_variant 0.25
Rv1979c 2222912 p.Ala85Ser missense_variant 0.17
Rv1979c 2223341 c.-177C>A upstream_gene_variant 0.15
kasA 2518101 c.-14G>T upstream_gene_variant 0.17
kasA 2518822 c.708C>G synonymous_variant 0.11
kasA 2518825 c.711T>C synonymous_variant 0.11
kasA 2518828 c.714G>C synonymous_variant 0.11
kasA 2518846 c.732G>C synonymous_variant 0.12
kasA 2518849 c.735G>C synonymous_variant 0.14
kasA 2518850 p.Met246Leu missense_variant 0.12
kasA 2518853 p.Leu247Ile missense_variant 0.13
kasA 2518864 c.750G>C synonymous_variant 0.21
kasA 2518879 c.765A>G synonymous_variant 0.2
kasA 2519083 c.969C>G synonymous_variant 0.17
kasA 2519095 c.981C>G synonymous_variant 0.15
kasA 2519099 p.Ala329Ser missense_variant 0.15
kasA 2519105 p.Cys331Val missense_variant 0.15
kasA 2519110 p.Asp332Glu missense_variant 0.14
kasA 2519113 p.Gln333His missense_variant 0.17
kasA 2519137 c.1023T>G synonymous_variant 0.17
kasA 2519140 c.1026G>C synonymous_variant 0.17
kasA 2519164 c.1050C>G synonymous_variant 0.2
kasA 2519170 c.1056G>C synonymous_variant 0.2
kasA 2519173 c.1059C>G synonymous_variant 0.2
kasA 2519180 p.Val356Ile missense_variant 0.29
kasA 2519185 c.1071C>G synonymous_variant 0.29
eis 2714892 c.441G>A synonymous_variant 0.22
eis 2715406 c.-74G>T upstream_gene_variant 0.25
folC 2746950 p.Ala217Thr missense_variant 0.12
folC 2747159 p.Pro147Leu missense_variant 0.22
pepQ 2859329 p.Arg364Trp missense_variant 0.17
Rv2752c 3064577 p.Lys539Glu missense_variant 0.11
Rv2752c 3064773 c.1419C>A synonymous_variant 0.13
Rv2752c 3064922 p.Glu424Lys missense_variant 0.12
Rv2752c 3065955 p.Leu79Phe missense_variant 0.12
thyX 3067226 p.Glu240Asp missense_variant 0.2
thyX 3067714 p.Val78Leu missense_variant 0.15
ald 3087058 p.Ala80Glu missense_variant 0.18
ald 3087113 c.294C>T synonymous_variant 0.25
ald 3087358 p.Gly180Val missense_variant 0.12
ald 3087638 c.819C>A synonymous_variant 0.2
fbiD 3339047 c.-71G>T upstream_gene_variant 0.13
fbiD 3339139 p.Gly8Cys missense_variant 0.14
Rv3083 3448804 p.Gly101Cys missense_variant 0.13
Rv3083 3449000 p.Pro166Gln missense_variant 0.17
Rv3083 3449713 p.Ala404Ser missense_variant 0.18
fprA 3474271 p.Gln89* stop_gained 0.17
fprA 3474670 p.Asp222His missense_variant 0.11
whiB7 3568692 c.-13G>T upstream_gene_variant 0.12
fbiB 3642652 p.Phe373Ser missense_variant 0.22
fbiB 3642753 p.Leu407Met missense_variant 0.29
ddn 3986645 c.-199G>A upstream_gene_variant 0.25
ddn 3986648 c.-196C>G upstream_gene_variant 0.23
ddn 3986659 c.-185A>G upstream_gene_variant 0.21
ddn 3986661 c.-183C>A upstream_gene_variant 0.21
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.19
ddn 3986696 c.-148G>C upstream_gene_variant 0.19
ddn 3986703 c.-141_-140delTCinsAG upstream_gene_variant 0.14
ddn 3987003 p.Arg54Cys missense_variant 0.17
clpC1 4038710 c.1995G>C synonymous_variant 0.11
clpC1 4038713 c.1992T>C synonymous_variant 0.11
clpC1 4038755 c.1950G>C synonymous_variant 0.11
clpC1 4038773 c.1932T>C synonymous_variant 0.11
clpC1 4038779 c.1926C>G synonymous_variant 0.12
clpC1 4038782 c.1923G>C synonymous_variant 0.13
clpC1 4039183 c.1522T>C synonymous_variant 0.18
clpC1 4039187 c.1518G>C synonymous_variant 0.18
clpC1 4039200 p.Ala502Asp missense_variant 0.12
clpC1 4039208 c.1497C>G synonymous_variant 0.19
clpC1 4039220 c.1485G>T synonymous_variant 0.14
clpC1 4039226 c.1479T>C synonymous_variant 0.14
clpC1 4039262 c.1443C>T synonymous_variant 0.14
clpC1 4039274 c.1431G>C synonymous_variant 0.13
clpC1 4039286 c.1419T>C synonymous_variant 0.12
clpC1 4039289 c.1416T>C synonymous_variant 0.12
clpC1 4039292 c.1413C>T synonymous_variant 0.12
clpC1 4039295 c.1410A>C synonymous_variant 0.12
clpC1 4039310 c.1395A>G synonymous_variant 0.16
clpC1 4039313 c.1392C>G synonymous_variant 0.16
clpC1 4039319 c.1386T>C synonymous_variant 0.18
clpC1 4039328 c.1377A>G synonymous_variant 0.14
clpC1 4039382 c.1323C>G synonymous_variant 0.17
clpC1 4039391 c.1314T>G synonymous_variant 0.17
clpC1 4039394 c.1311G>C synonymous_variant 0.12
clpC1 4039397 c.1308A>G synonymous_variant 0.12
clpC1 4039409 c.1296T>C synonymous_variant 0.14
clpC1 4039412 c.1293T>G synonymous_variant 0.13
clpC1 4039415 p.Glu430Asp missense_variant 0.14
clpC1 4039430 c.1275T>C synonymous_variant 0.14
clpC1 4039442 c.1263A>G synonymous_variant 0.15
clpC1 4039448 c.1257A>G synonymous_variant 0.15
clpC1 4039454 c.1251A>T synonymous_variant 0.15
clpC1 4039640 c.1065C>G synonymous_variant 0.11
clpC1 4039649 c.1056G>C synonymous_variant 0.11
clpC1 4039652 c.1053G>C synonymous_variant 0.11
clpC1 4039661 c.1044T>C synonymous_variant 0.11
clpC1 4039664 c.1041G>C synonymous_variant 0.11
clpC1 4039694 c.1011G>C synonymous_variant 0.14
clpC1 4039718 c.987C>G synonymous_variant 0.12
clpC1 4039724 c.981A>G synonymous_variant 0.12
clpC1 4039733 c.972G>C synonymous_variant 0.13
clpC1 4040551 c.154T>C synonymous_variant 0.12
clpC1 4040558 c.147G>C synonymous_variant 0.14
clpC1 4040561 c.144A>G synonymous_variant 0.14
clpC1 4040573 c.132T>C synonymous_variant 0.14
clpC1 4040579 c.126A>G synonymous_variant 0.13
clpC1 4040582 c.123G>C synonymous_variant 0.13
clpC1 4040585 c.120A>G synonymous_variant 0.14
clpC1 4040588 c.117T>C synonymous_variant 0.14
clpC1 4040594 c.111G>C synonymous_variant 0.14
clpC1 4040600 c.103_105delTTAinsCTC synonymous_variant 0.13
clpC1 4040603 c.102T>G synonymous_variant 0.13
clpC1 4040606 c.99T>C synonymous_variant 0.13
panD 4044365 c.-84C>A upstream_gene_variant 0.18
embC 4241279 p.Val473Leu missense_variant 0.17
embC 4242197 p.Ala779Ser missense_variant 0.25
embA 4242247 c.-986C>A upstream_gene_variant 0.29
embC 4242255 p.Pro798Gln missense_variant 0.25
embA 4242844 c.-389A>G upstream_gene_variant 0.13
embA 4243701 p.Gly157Ser missense_variant 0.17
embA 4245451 p.Leu740Pro missense_variant 0.12
embB 4245644 c.-870C>A upstream_gene_variant 0.13
embB 4247806 c.1293G>A synonymous_variant 0.13
embB 4248204 p.Pro564His missense_variant 0.12
embB 4248231 p.Arg573Leu missense_variant 0.12
embB 4248532 p.Phe673Leu missense_variant 0.17
embB 4249088 p.Val859Ile missense_variant 0.18
aftB 4267647 p.Asp397Gly missense_variant 0.2
aftB 4267846 p.Gly331Ser missense_variant 0.13
aftB 4267978 p.Pro287Thr missense_variant 0.25
whiB6 4338595 c.-75delG upstream_gene_variant 0.19
gid 4407535 p.Thr223Lys missense_variant 0.15
gid 4407588 c.615A>G synonymous_variant 0.12
gid 4408263 c.-61G>T upstream_gene_variant 0.22
gid 4408296 c.-94C>A upstream_gene_variant 0.25
gid 4408331 c.-129C>A upstream_gene_variant 0.22