TB-Profiler result

Run: ERR3797024
Summary

Run ID: ERR3797024

Sample name:

Date: 01-04-2023 03:02:34

Number of reads: 30303

Percentage reads mapped: 18.58

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.99
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6634 c.-668T>C upstream_gene_variant 0.67
gyrA 6637 c.-665T>G upstream_gene_variant 0.67
gyrA 6640 c.-662A>C upstream_gene_variant 0.67
gyrA 6643 c.-659A>G upstream_gene_variant 0.67
gyrA 6649 c.-653T>C upstream_gene_variant 0.67
gyrA 6655 c.-647T>C upstream_gene_variant 0.67
gyrA 6760 c.-542G>C upstream_gene_variant 0.67
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7442 c.141G>T synonymous_variant 0.5
gyrA 7451 c.150C>G synonymous_variant 0.75
gyrA 7457 c.156T>C synonymous_variant 0.75
gyrA 7463 c.162G>C synonymous_variant 0.5
gyrA 7469 c.168C>G synonymous_variant 0.5
gyrA 7472 c.171T>C synonymous_variant 0.75
gyrA 7475 c.174A>G synonymous_variant 0.67
gyrA 7480 p.Phe60Tyr missense_variant 0.75
gyrA 7484 c.183T>C synonymous_variant 0.75
gyrA 7490 c.189C>G synonymous_variant 0.67
gyrA 7523 c.222C>G synonymous_variant 0.67
gyrA 7541 c.240C>G synonymous_variant 0.67
gyrA 8438 c.1137C>T synonymous_variant 1.0
gyrA 8453 c.1152A>C synonymous_variant 1.0
gyrA 8459 c.1158G>A synonymous_variant 1.0
gyrA 8462 c.1161A>G synonymous_variant 1.0
gyrA 8468 c.1167C>T synonymous_variant 1.0
gyrA 8486 c.1185T>C synonymous_variant 1.0
gyrA 8489 c.1188A>G synonymous_variant 1.0
gyrA 8510 c.1209G>A synonymous_variant 1.0
gyrA 8561 c.1260A>G synonymous_variant 1.0
gyrA 8573 c.1272G>C synonymous_variant 1.0
gyrA 9023 c.1722A>C synonymous_variant 1.0
gyrA 9029 c.1728T>G synonymous_variant 1.0
gyrA 9050 p.Asp583Glu missense_variant 1.0
gyrA 9051 c.1750T>C synonymous_variant 1.0
gyrA 9056 c.1755C>G synonymous_variant 1.0
gyrA 9062 c.1761C>T synonymous_variant 1.0
gyrA 9071 c.1770G>C synonymous_variant 1.0
gyrA 9074 c.1773G>C synonymous_variant 1.0
gyrA 9080 c.1779G>T synonymous_variant 1.0
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 1.0
gyrA 9104 c.1803C>T synonymous_variant 1.0
gyrA 9119 c.1818A>G synonymous_variant 1.0
gyrA 9131 c.1830G>A synonymous_variant 1.0
gyrA 9134 c.1833C>G synonymous_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9153 p.Thr618Ala missense_variant 1.0
fgd1 490887 c.105G>C synonymous_variant 1.0
fgd1 490902 c.120T>C synonymous_variant 1.0
fgd1 490905 c.123T>C synonymous_variant 1.0
fgd1 490911 c.129T>G synonymous_variant 1.0
fgd1 490921 p.Gln47Glu missense_variant 0.67
fgd1 491191 p.Gly137Arg missense_variant 1.0
fgd1 491196 c.414A>G synonymous_variant 1.0
fgd1 491244 c.462T>C synonymous_variant 0.5
fgd1 491259 c.477T>C synonymous_variant 0.5
fgd1 491286 c.504G>C synonymous_variant 0.5
fgd1 491292 c.510G>C synonymous_variant 0.5
fgd1 491295 c.513C>G synonymous_variant 0.5
fgd1 491296 p.Val172Ile missense_variant 0.5
fgd1 491331 c.549G>A synonymous_variant 0.67
mshA 575629 c.282A>G synonymous_variant 0.5
mshA 575632 c.285G>C synonymous_variant 0.5
mshA 575635 c.288A>C synonymous_variant 0.5
mshA 575641 c.294A>G synonymous_variant 0.5
mshA 575647 c.300G>C synonymous_variant 0.5
mshA 575649 p.Val101Glu missense_variant 0.5
mshA 575659 c.312A>G synonymous_variant 0.5
ccsA 620295 c.405G>T synonymous_variant 0.67
ccsA 620307 c.417C>A synonymous_variant 0.67
ccsA 620319 c.429C>G synonymous_variant 0.67
ccsA 620367 c.477T>C synonymous_variant 1.0
ccsA 620373 c.483C>G synonymous_variant 1.0
ccsA 620385 c.495G>C synonymous_variant 1.0
ccsA 620388 c.498A>G synonymous_variant 1.0
ccsA 620409 c.519C>G synonymous_variant 1.0
ccsA 620415 c.525T>C synonymous_variant 1.0
ccsA 620433 c.543C>G synonymous_variant 1.0
ccsA 620436 c.546T>C synonymous_variant 1.0
ccsA 620439 c.549T>G synonymous_variant 1.0
rpoB 760223 c.417T>C synonymous_variant 0.67
rpoB 760235 c.429T>C synonymous_variant 0.67
rpoB 760475 c.669A>G synonymous_variant 1.0
rpoB 760481 c.675G>C synonymous_variant 1.0
rpoB 760484 c.678A>G synonymous_variant 1.0
rpoB 760514 c.708C>T synonymous_variant 1.0
rpoB 760522 p.Ser239Asn missense_variant 0.67
rpoB 760532 c.726T>C synonymous_variant 0.67
rpoB 760533 p.Val243Thr missense_variant 0.67
rpoB 760547 c.741G>C synonymous_variant 0.67
rpoB 760856 c.1050C>G synonymous_variant 1.0
rpoB 760862 c.1056G>C synonymous_variant 1.0
rpoB 760886 c.1080A>G synonymous_variant 1.0
rpoB 760919 c.1113C>G synonymous_variant 1.0
rpoB 760925 c.1119T>C synonymous_variant 1.0
rpoB 760934 c.1128C>G synonymous_variant 1.0
rpoB 760946 c.1140A>G synonymous_variant 1.0
rpoB 760958 c.1152G>C synonymous_variant 1.0
rpoB 761180 c.1374A>G synonymous_variant 0.67
rpoB 761195 c.1389G>C synonymous_variant 0.67
rpoB 761196 c.1390C>T synonymous_variant 0.67
rpoB 761207 c.1401C>T synonymous_variant 0.67
rpoB 761249 c.1443A>G synonymous_variant 0.67
rpoB 762101 c.2295C>G synonymous_variant 0.67
rpoB 762114 p.Ile770Val missense_variant 0.67
rpoB 762119 c.2313C>T synonymous_variant 0.67
rpoB 762131 c.2325C>G synonymous_variant 0.67
rpoB 762143 c.2337T>C synonymous_variant 0.67
rpoB 762149 c.2343G>T synonymous_variant 0.67
rpoB 762167 c.2361T>C synonymous_variant 1.0
rpoB 762185 c.2379G>C synonymous_variant 1.0
rpoB 762218 c.2412T>C synonymous_variant 0.83
rpoB 762254 c.2448T>G synonymous_variant 0.67
rpoB 762257 c.2451C>G synonymous_variant 0.67
rpoB 762266 c.2460T>C synonymous_variant 0.67
rpoB 762284 c.2478G>C synonymous_variant 1.0
rpoB 762293 c.2487T>C synonymous_variant 1.0
rpoB 762297 c.2491C>T synonymous_variant 0.75
rpoB 762317 c.2511A>G synonymous_variant 1.0
rpoB 762338 c.2532T>C synonymous_variant 1.0
rpoB 762347 c.2541T>C synonymous_variant 1.0
rpoB 762362 p.Glu852Asp missense_variant 1.0
rpoB 762369 c.2563T>C synonymous_variant 1.0
rpoC 762410 c.-960T>C upstream_gene_variant 1.0
rpoC 762416 c.-954A>G upstream_gene_variant 1.0
rpoC 762434 c.-936T>C upstream_gene_variant 1.0
rpoC 762470 c.-900G>C upstream_gene_variant 1.0
rpoB 762490 p.Val895Ala missense_variant 1.0
rpoC 762509 c.-861T>G upstream_gene_variant 1.0
rpoB 762510 p.Ala902Pro missense_variant 1.0
rpoC 762521 c.-849C>G upstream_gene_variant 0.8
rpoC 762533 c.-837T>C upstream_gene_variant 0.75
rpoC 762536 c.-834T>C upstream_gene_variant 0.75
rpoC 762537 c.-833T>C upstream_gene_variant 0.75
rpoC 762551 c.-819C>T upstream_gene_variant 0.75
rpoC 762989 c.-381G>C upstream_gene_variant 0.4
rpoC 762995 c.-375G>T upstream_gene_variant 0.4
rpoC 763028 c.-342T>C upstream_gene_variant 0.4
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763034 c.-336C>G upstream_gene_variant 0.4
rpoC 763040 c.-330C>G upstream_gene_variant 0.4
rpoC 763052 c.-318G>C upstream_gene_variant 0.4
rpoC 763070 c.-300T>C upstream_gene_variant 0.4
rpoC 763076 c.-294C>G upstream_gene_variant 0.4
rpoC 763082 c.-288C>G upstream_gene_variant 0.4
rpoC 763085 c.-285C>G upstream_gene_variant 0.5
rpoC 763094 c.-276G>C upstream_gene_variant 0.5
rpoC 763115 c.-255T>C upstream_gene_variant 0.75
rpoC 763486 c.117T>G synonymous_variant 1.0
rpoC 763528 c.159G>A synonymous_variant 1.0
rpoC 763537 c.168C>G synonymous_variant 1.0
rpoC 763546 c.177A>G synonymous_variant 1.0
rpoC 763570 c.201G>C synonymous_variant 1.0
rpoC 763573 c.204G>C synonymous_variant 1.0
rpoC 763594 c.225C>T synonymous_variant 1.0
rpoC 763600 c.231C>G synonymous_variant 1.0
rpoC 763858 c.489A>G synonymous_variant 1.0
rpoC 763871 p.Gly168Thr missense_variant 1.0
rpoC 763879 c.510A>G synonymous_variant 1.0
rpoC 763888 c.519G>T synonymous_variant 1.0
rpoC 763894 c.525A>G synonymous_variant 1.0
rpoC 765292 c.1923G>T synonymous_variant 1.0
rpoC 765300 p.Val644Ala missense_variant 1.0
rpoC 765327 p.His653Pro missense_variant 1.0
rpoC 765349 c.1980T>C synonymous_variant 1.0
rpoC 766522 c.3153C>G synonymous_variant 1.0
rpoC 766528 c.3159T>C synonymous_variant 1.0
rpoC 766531 c.3162G>T synonymous_variant 1.0
rpoC 766540 p.Asp1057Glu missense_variant 1.0
rpoC 766549 c.3180G>C synonymous_variant 1.0
rpoC 766573 c.3204T>C synonymous_variant 1.0
rpoC 766582 c.3213C>G synonymous_variant 1.0
rpoC 766585 c.3216T>C synonymous_variant 1.0
rpoC 766591 c.3222A>G synonymous_variant 1.0
rpoC 766594 c.3225G>C synonymous_variant 1.0
rpoC 766597 c.3228C>G synonymous_variant 1.0
rpoC 766607 p.Ile1080Leu missense_variant 1.0
rpoC 766627 c.3258G>C synonymous_variant 1.0
rpoC 766996 c.3627C>T synonymous_variant 1.0
rpoC 767032 c.3663G>C synonymous_variant 1.0
rpoC 767059 c.3690T>G synonymous_variant 1.0
rpoC 767062 c.3693C>G synonymous_variant 1.0
rpoC 767098 c.3729T>C synonymous_variant 1.0
rpsL 781608 p.Ser17Gly missense_variant 1.0
rpsL 781628 c.69T>C synonymous_variant 1.0
rpsL 781649 c.90T>C synonymous_variant 1.0
rpsL 781655 c.96T>C synonymous_variant 1.0
rpsL 781682 c.123T>G synonymous_variant 1.0
rpsL 781715 c.156T>C synonymous_variant 0.8
rpsL 781718 c.159C>G synonymous_variant 0.8
rpsL 781728 c.169T>C synonymous_variant 0.75
rpsL 781736 c.177T>C synonymous_variant 0.67
rpsL 781754 c.195G>C synonymous_variant 0.67
rpsL 781832 c.273T>C synonymous_variant 0.67
rpsL 781835 c.276T>C synonymous_variant 0.67
rpsL 781841 c.282C>G synonymous_variant 0.67
rpsL 781865 c.306G>C synonymous_variant 0.67
rpsL 781868 c.309T>C synonymous_variant 1.0
rpsL 781871 c.312G>C synonymous_variant 1.0
rpsL 781877 c.318T>C synonymous_variant 1.0
rpsL 781892 c.333A>G synonymous_variant 1.0
rpsL 781898 c.339A>T synonymous_variant 0.67
rpsL 781929 p.Gly124Ser missense_variant 0.67
rplC 800612 c.-197A>G upstream_gene_variant 1.0
rplC 800618 c.-191T>C upstream_gene_variant 1.0
rplC 800648 c.-161A>T upstream_gene_variant 1.0
rplC 800715 c.-94A>C upstream_gene_variant 1.0
rplC 800814 c.6A>G synonymous_variant 1.0
rplC 800844 c.36T>C synonymous_variant 1.0
fbiC 1303674 c.744C>G synonymous_variant 0.5
fbiC 1303695 c.765T>C synonymous_variant 0.5
fbiC 1303731 c.801A>G synonymous_variant 0.5
fbiC 1303732 p.Ser268Pro missense_variant 0.5
fbiC 1303737 c.807G>A synonymous_variant 0.5
fbiC 1303746 c.816T>C synonymous_variant 0.4
fbiC 1303749 c.819G>C synonymous_variant 0.5
fbiC 1303752 c.822A>G synonymous_variant 0.5
fbiC 1303755 c.825T>C synonymous_variant 0.5
fbiC 1303789 p.Ile287Val missense_variant 0.67
fbiC 1303794 c.864A>G synonymous_variant 0.67
fbiC 1303806 c.876G>A synonymous_variant 0.67
fbiC 1303809 c.879G>A synonymous_variant 0.67
fbiC 1304787 c.1857T>C synonymous_variant 0.5
fbiC 1304808 c.1878C>G synonymous_variant 0.67
fbiC 1304811 c.1881C>G synonymous_variant 0.67
fbiC 1304817 c.1887T>C synonymous_variant 0.67
fbiC 1304829 c.1899T>C synonymous_variant 0.67
fbiC 1304856 c.1926C>G synonymous_variant 0.67
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0
rrs 1472085 n.240C>G non_coding_transcript_exon_variant 0.75
rrs 1472086 n.241T>C non_coding_transcript_exon_variant 0.75
rrs 1472089 n.244C>T non_coding_transcript_exon_variant 0.8
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.89
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.92
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.92
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.92
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.93
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.93
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.94
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.95
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.95
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.95
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.95
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.93
rrs 1472223 n.378C>G non_coding_transcript_exon_variant 0.98
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.98
rrs 1472228 n.383G>C non_coding_transcript_exon_variant 0.98
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.97
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.97
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.94
rrs 1472277 n.432C>G non_coding_transcript_exon_variant 0.83
rrs 1472282 n.437T>G non_coding_transcript_exon_variant 0.6
rrs 1472498 n.653C>G non_coding_transcript_exon_variant 0.67
rrs 1472505 n.660G>A non_coding_transcript_exon_variant 0.89
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.92
rrs 1472518 n.673G>A non_coding_transcript_exon_variant 0.95
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.96
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.96
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.96
rrs 1472544 n.699C>T non_coding_transcript_exon_variant 0.96
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.96
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.96
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.96
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.96
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.96
rrs 1472579 n.734G>A non_coding_transcript_exon_variant 0.96
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.96
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.96
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.96
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.95
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.97
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.97
rrs 1472659 n.814G>A non_coding_transcript_exon_variant 0.97
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.96
rrs 1472678 n.834_840delTCCTTGG non_coding_transcript_exon_variant 0.96
rrs 1472687 n.842_843insCC non_coding_transcript_exon_variant 0.96
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.96
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.96
rrs 1472698 n.853A>C non_coding_transcript_exon_variant 0.96
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 0.96
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.96
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.96
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.96
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.96
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.75
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.75
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.8
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.8
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.4
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.4
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 1.0
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.67
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0
rrl 1474950 n.1293G>A non_coding_transcript_exon_variant 0.67
rrl 1474952 n.1296_1300delCATCC non_coding_transcript_exon_variant 1.0
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.67
rrl 1474962 n.1305T>C non_coding_transcript_exon_variant 1.0
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 1.0
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.67
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 1.0
rrl 1474997 n.1340A>T non_coding_transcript_exon_variant 0.75
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 1.0
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 1.0
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 1.0
rrl 1475253 n.1596T>G non_coding_transcript_exon_variant 1.0
rrl 1475273 n.1616T>G non_coding_transcript_exon_variant 1.0
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 1.0
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 1.0
rrl 1475289 n.1632G>A non_coding_transcript_exon_variant 1.0
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 1.0
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 1.0
rrl 1475366 n.1709G>A non_coding_transcript_exon_variant 1.0
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 1.0
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 1.0
rrl 1476238 n.2581T>C non_coding_transcript_exon_variant 0.89
rrl 1476248 n.2591G>C non_coding_transcript_exon_variant 0.89
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0
rrl 1476252 n.2595T>C non_coding_transcript_exon_variant 0.89
rrl 1476259 n.2602C>G non_coding_transcript_exon_variant 0.89
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.89
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.88
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.82
rrl 1476298 n.2642_2644delCGA non_coding_transcript_exon_variant 0.82
rrl 1476306 n.2649A>G non_coding_transcript_exon_variant 0.78
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.83
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.83
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.83
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.91
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.92
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.96
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.95
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.97
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.97
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.96
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.97
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.97
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.96
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.97
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.97
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.96
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.96
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.96
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.94
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.94
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.94
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.94
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.94
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.93
rrl 1476572 n.2915G>T non_coding_transcript_exon_variant 0.89
rrl 1476573 n.2916A>G non_coding_transcript_exon_variant 0.92
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.86
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.8
rrl 1476608 n.2951C>A non_coding_transcript_exon_variant 0.73
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 0.33
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0
inhA 1674542 p.Ala114Glu missense_variant 1.0
inhA 1674546 c.345T>C synonymous_variant 1.0
inhA 1674549 c.348G>C synonymous_variant 1.0
inhA 1674550 p.Ser117Ala missense_variant 1.0
inhA 1674570 c.369G>C synonymous_variant 1.0
inhA 1674576 c.375T>C synonymous_variant 1.0
inhA 1674582 c.381T>C synonymous_variant 1.0
inhA 1674585 c.384T>C synonymous_variant 1.0
inhA 1674589 p.Met130Leu missense_variant 1.0
inhA 1674624 c.423A>C synonymous_variant 1.0
inhA 1674627 c.426T>C synonymous_variant 1.0
inhA 1674628 p.Ser143Gly missense_variant 1.0
inhA 1674654 c.453G>C synonymous_variant 1.0
inhA 1674660 c.459G>T synonymous_variant 1.0
inhA 1674663 c.462G>C synonymous_variant 1.0
inhA 1674703 c.502T>C synonymous_variant 1.0
inhA 1674714 c.513C>G synonymous_variant 1.0
inhA 1674718 c.517A>C synonymous_variant 1.0
inhA 1674726 c.525G>A synonymous_variant 1.0
inhA 1674729 c.528G>C synonymous_variant 1.0
inhA 1674750 c.549T>C synonymous_variant 1.0
inhA 1674756 c.555T>C synonymous_variant 1.0
inhA 1674765 c.564C>T synonymous_variant 1.0
inhA 1674771 c.570C>G synonymous_variant 1.0
inhA 1674777 c.576C>G synonymous_variant 1.0
inhA 1674780 c.579T>G synonymous_variant 1.0
inhA 1674792 c.591G>C synonymous_variant 1.0
inhA 1674801 c.600T>C synonymous_variant 1.0
inhA 1674816 c.615T>A synonymous_variant 1.0
inhA 1674822 c.621C>G synonymous_variant 1.0
inhA 1674825 c.624C>T synonymous_variant 1.0
inhA 1674846 c.645C>A synonymous_variant 1.0
inhA 1674957 c.756G>A synonymous_variant 1.0
inhA 1674966 c.765T>C synonymous_variant 1.0
inhA 1674967 p.Asp256Thr missense_variant 1.0
inhA 1674970 p.Ile257Val missense_variant 1.0
rpsA 1833673 c.132C>A synonymous_variant 0.67
rpsA 1833724 c.183C>G synonymous_variant 1.0
rpsA 1833727 c.186G>C synonymous_variant 1.0
rpsA 1833742 c.201A>G synonymous_variant 1.0
rpsA 1833745 c.204G>C synonymous_variant 1.0
rpsA 1833760 c.219C>T synonymous_variant 0.75
rpsA 1833787 c.246C>G synonymous_variant 1.0
rpsA 1833790 c.249T>C synonymous_variant 1.0
rpsA 1833793 c.252C>T synonymous_variant 1.0
rpsA 1833856 c.315A>G synonymous_variant 1.0
rpsA 1833874 c.333T>C synonymous_variant 1.0
ndh 2101838 p.Ala402Val missense_variant 0.5
ndh 2101858 p.Ile395Met missense_variant 0.5
ndh 2101873 c.1170T>C synonymous_variant 0.5
ndh 2101888 p.Val385Leu missense_variant 0.5
ndh 2101891 c.1152C>G synonymous_variant 0.5
ndh 2101912 c.1131G>C synonymous_variant 0.5
ndh 2101920 c.1123A>C synonymous_variant 0.75
ndh 2101924 c.1119T>G synonymous_variant 0.75
ndh 2101936 c.1107G>C synonymous_variant 0.75
ndh 2101939 c.1104A>G synonymous_variant 0.75
ndh 2101960 c.1083A>C synonymous_variant 0.75
ndh 2102269 c.774C>G synonymous_variant 1.0
ndh 2102287 c.756C>G synonymous_variant 0.67
ndh 2102311 c.732G>A synonymous_variant 0.67
ndh 2102317 c.726A>G synonymous_variant 0.67
ndh 2102320 c.723G>C synonymous_variant 0.67
ndh 2102341 c.702C>A synonymous_variant 0.67
ndh 2102344 c.699T>C synonymous_variant 0.67
ndh 2102366 p.Ala226Glu missense_variant 0.67
ndh 2102377 c.666A>G synonymous_variant 0.67
ndh 2102382 c.661C>T synonymous_variant 0.67
ndh 2102389 c.654G>C synonymous_variant 0.67
ndh 2102392 c.651C>G synonymous_variant 0.67
ndh 2102401 c.642T>C synonymous_variant 0.67
ndh 2102680 c.363T>C synonymous_variant 1.0
ndh 2102683 c.360T>C synonymous_variant 1.0
ndh 2102712 p.Pro111Ser missense_variant 1.0
ndh 2102718 p.Gln109Glu missense_variant 1.0
ndh 2102728 c.315T>C synonymous_variant 1.0
ndh 2102737 p.Glu102Asp missense_variant 1.0
ndh 2102740 c.303G>C synonymous_variant 1.0
ndh 2102743 c.300C>G synonymous_variant 1.0
ndh 2102746 c.297C>G synonymous_variant 1.0
ndh 2102750 p.Cys98Thr missense_variant 1.0
ndh 2102755 p.Gly96Asn missense_variant 1.0
ndh 2102771 p.His91Gly missense_variant 1.0
ndh 2102787 c.256T>C synonymous_variant 1.0
ndh 2102791 c.252A>G synonymous_variant 1.0
ndh 2102830 c.213G>C synonymous_variant 1.0
kasA 2517920 c.-195G>A upstream_gene_variant 1.0
kasA 2518699 p.Cys195* stop_gained 1.0
kasA 2518711 c.597A>G synonymous_variant 1.0
kasA 2518714 c.600A>C synonymous_variant 1.0
kasA 2518717 c.603C>G synonymous_variant 1.0
kasA 2518747 c.633C>G synonymous_variant 1.0
kasA 2518783 c.669T>C synonymous_variant 1.0
kasA 2518789 c.675G>C synonymous_variant 1.0
kasA 2518795 c.681C>A synonymous_variant 1.0
kasA 2518798 c.684G>T synonymous_variant 1.0
kasA 2518825 c.711T>C synonymous_variant 1.0
kasA 2518843 c.729T>G synonymous_variant 0.67
kasA 2518849 c.735G>C synonymous_variant 0.67
kasA 2519152 c.1038G>C synonymous_variant 0.67
kasA 2519167 c.1053T>C synonymous_variant 1.0
kasA 2519173 c.1059C>G synonymous_variant 1.0
kasA 2519176 c.1062G>A synonymous_variant 1.0
kasA 2519179 c.1065G>T synonymous_variant 0.67
kasA 2519182 c.1068G>C synonymous_variant 0.67
kasA 2519191 c.1077G>A synonymous_variant 0.67
kasA 2519192 c.1078C>T synonymous_variant 0.67
kasA 2519197 c.1083G>C synonymous_variant 1.0
kasA 2519200 c.1086G>T synonymous_variant 0.67
kasA 2519203 c.1089C>G synonymous_variant 0.67
kasA 2519215 c.1101C>A synonymous_variant 1.0
kasA 2519221 c.1107G>C synonymous_variant 1.0
kasA 2519224 c.1110C>G synonymous_variant 1.0
kasA 2519239 c.1125A>C synonymous_variant 1.0
kasA 2519263 c.1149C>T synonymous_variant 1.0
kasA 2519266 c.1152C>T synonymous_variant 1.0
kasA 2519272 c.1158C>G synonymous_variant 1.0
kasA 2519281 c.1167G>T synonymous_variant 1.0
folC 2746728 c.871T>C synonymous_variant 1.0
folC 2746734 p.Ile289Val missense_variant 1.0
folC 2746744 c.855T>G synonymous_variant 1.0
folC 2746759 c.840G>A synonymous_variant 1.0
folC 2746765 c.834A>G synonymous_variant 1.0
folC 2746771 c.828A>C synonymous_variant 1.0
folC 2746777 c.822T>A synonymous_variant 1.0
folC 2746785 p.Val272Ile missense_variant 1.0
folC 2746791 p.Ile270Val missense_variant 1.0
folC 2746793 p.Gln269Arg missense_variant 1.0
folC 2746795 c.804A>C synonymous_variant 1.0
folC 2746798 p.Arg267Gly missense_variant 1.0
folC 2746801 c.796_798delCTAinsTTG synonymous_variant 1.0
folC 2746813 c.786A>G synonymous_variant 1.0
folC 2746819 c.780T>C synonymous_variant 1.0
folC 2746836 p.Ser255Ala missense_variant 1.0
folC 2746837 c.762G>C synonymous_variant 1.0
pepQ 2859432 c.987T>C synonymous_variant 0.67
pepQ 2859438 c.981T>C synonymous_variant 0.67
pepQ 2859468 c.951G>T synonymous_variant 0.67
pepQ 2859471 c.948A>G synonymous_variant 0.67
pepQ 2859486 c.933A>G synonymous_variant 0.67
pepQ 2859489 p.Val310Ala missense_variant 0.67
pepQ 2859492 c.927G>C synonymous_variant 0.67
pepQ 2859498 c.921C>A synonymous_variant 0.67
pepQ 2859510 c.909T>C synonymous_variant 1.0
pepQ 2859513 c.906A>C synonymous_variant 1.0
pepQ 2859525 c.894T>G synonymous_variant 1.0
pepQ 2859528 c.891T>C synonymous_variant 1.0
pepQ 2859534 c.885A>G synonymous_variant 1.0
pepQ 2859539 c.880C>T synonymous_variant 1.0
pepQ 2859540 c.879A>T synonymous_variant 1.0
pepQ 2859546 c.873T>C synonymous_variant 1.0
pepQ 2859552 p.His289Gln missense_variant 0.67
pepQ 2859870 c.549T>C synonymous_variant 1.0
pepQ 2859873 c.546T>C synonymous_variant 1.0
pepQ 2859908 p.Gln171Glu missense_variant 1.0
pepQ 2859909 c.510G>C synonymous_variant 1.0
pepQ 2859918 c.501A>C synonymous_variant 1.0
pepQ 2859921 c.498C>G synonymous_variant 1.0
pepQ 2859924 c.495G>C synonymous_variant 1.0
pepQ 2859942 c.477C>G synonymous_variant 1.0
pepQ 2859950 c.469T>C synonymous_variant 1.0
pepQ 2859951 c.468C>T synonymous_variant 1.0
pepQ 2859966 c.453T>C synonymous_variant 1.0
pepQ 2859972 c.447A>G synonymous_variant 1.0
pepQ 2859975 c.444A>G synonymous_variant 1.0
pepQ 2859984 c.435A>G synonymous_variant 1.0
pepQ 2859987 c.432A>G synonymous_variant 1.0
pepQ 2860001 p.Leu140Val missense_variant 1.0
thyA 3073860 c.612C>G synonymous_variant 1.0
thyA 3073863 c.609T>C synonymous_variant 1.0
thyA 3073874 p.Ile200Val missense_variant 1.0
thyA 3073887 p.Ser195Gly missense_variant 1.0
thyA 3073892 c.580T>C synonymous_variant 1.0
thyA 3073893 c.579C>A synonymous_variant 1.0
thyA 3073908 p.Met188Ile missense_variant 1.0
thyA 3073923 c.547_549delTTGinsCTA synonymous_variant 1.0
thyA 3073929 c.543T>C synonymous_variant 1.0
thyA 3073950 c.522G>C synonymous_variant 1.0
thyA 3073953 c.519T>C synonymous_variant 1.0
thyA 3073956 c.516G>C synonymous_variant 1.0
thyA 3073959 c.513T>C synonymous_variant 1.0
thyA 3073977 c.495A>G synonymous_variant 1.0
ald 3086728 c.-92C>T upstream_gene_variant 1.0
fbiB 3641834 c.300G>T synonymous_variant 0.67
fbiB 3641840 c.306T>C synonymous_variant 0.67
fbiB 3641846 c.312G>C synonymous_variant 1.0
fbiB 3641877 p.Arg115Ser missense_variant 0.75
fbiB 3641880 p.Ser116Asp missense_variant 0.75
fbiB 3641885 c.351G>A synonymous_variant 0.75
fbiB 3641888 c.354A>G synonymous_variant 0.75
fbiB 3641909 c.375T>C synonymous_variant 0.75
fbiB 3641918 c.384T>C synonymous_variant 0.75
fbiB 3641924 c.390A>G synonymous_variant 0.75
fbiB 3641925 p.Thr131Ala missense_variant 0.75
fbiB 3641928 c.394T>C synonymous_variant 0.75
fbiB 3641933 c.399C>G synonymous_variant 0.75
fbiB 3641945 c.411C>G synonymous_variant 0.75
fbiB 3641961 p.Thr143Asp missense_variant 0.75
clpC1 4038623 c.2082A>G synonymous_variant 1.0
clpC1 4038658 p.Lys683Gln missense_variant 1.0
clpC1 4038661 p.Ser682Thr missense_variant 1.0
clpC1 4038662 c.2043T>C synonymous_variant 1.0
clpC1 4038671 c.2034T>C synonymous_variant 1.0
clpC1 4038683 c.2022T>G synonymous_variant 1.0
clpC1 4038704 c.2001T>C synonymous_variant 1.0
clpC1 4038710 c.1995G>C synonymous_variant 1.0
clpC1 4038713 c.1992T>C synonymous_variant 1.0
clpC1 4038755 c.1950G>C synonymous_variant 1.0
clpC1 4039391 c.1314T>C synonymous_variant 1.0
clpC1 4039406 c.1299G>C synonymous_variant 1.0
clpC1 4039409 c.1296T>C synonymous_variant 1.0
clpC1 4039412 c.1293T>C synonymous_variant 1.0
clpC1 4039430 c.1275T>C synonymous_variant 1.0
clpC1 4039442 c.1263A>G synonymous_variant 1.0
clpC1 4039463 c.1242C>G synonymous_variant 1.0
clpC1 4039466 c.1239T>C synonymous_variant 1.0
clpC1 4039469 c.1236T>C synonymous_variant 1.0
clpC1 4039481 c.1224T>C synonymous_variant 1.0
clpC1 4039484 c.1221T>C synonymous_variant 1.0
clpC1 4039517 c.1188C>G synonymous_variant 1.0
clpC1 4039904 c.801A>G synonymous_variant 1.0
clpC1 4039913 c.792C>T synonymous_variant 0.67
clpC1 4040021 c.684A>C synonymous_variant 0.5
clpC1 4040024 c.681A>G synonymous_variant 0.5
clpC1 4040033 c.672G>C synonymous_variant 0.5
embC 4241050 c.1188T>G synonymous_variant 0.67
embC 4241071 c.1209C>G synonymous_variant 0.67
embC 4241095 c.1233C>T synonymous_variant 0.67
embC 4241107 c.1245G>C synonymous_variant 0.67
embC 4241140 c.1278A>G synonymous_variant 1.0
embC 4241158 c.1296T>C synonymous_variant 1.0
embC 4241161 c.1299C>G synonymous_variant 1.0
embC 4241162 c.1300T>C synonymous_variant 1.0
embC 4241167 c.1305C>G synonymous_variant 1.0
embB 4246292 c.-222A>G upstream_gene_variant 1.0
embA 4246299 p.Ser1023Ala missense_variant 0.67
embA 4246305 p.Ser1025Glu missense_variant 1.0
embB 4246316 c.-198T>C upstream_gene_variant 1.0
embB 4246352 c.-162G>C upstream_gene_variant 0.67
embA 4246359 p.Ala1043Ser missense_variant 1.0
embB 4246373 c.-141T>C upstream_gene_variant 1.0
embB 4246376 c.-138G>C upstream_gene_variant 1.0
embB 4246385 c.-129T>C upstream_gene_variant 0.67
embB 4246400 c.-114G>C upstream_gene_variant 0.67
embA 4246413 p.His1061Tyr missense_variant 1.0
embB 4246419 c.-95C>T upstream_gene_variant 1.0
embB 4247437 c.924A>G synonymous_variant 1.0
embB 4247470 c.957T>C synonymous_variant 1.0
embB 4247491 c.978G>C synonymous_variant 0.75
embB 4247497 c.984T>C synonymous_variant 0.75
embB 4247500 c.987C>G synonymous_variant 0.75
embB 4247512 c.999T>C synonymous_variant 0.75
embB 4247539 c.1026T>C synonymous_variant 0.67
embB 4247550 p.Ala346Asp missense_variant 0.67
embB 4247554 c.1041T>C synonymous_variant 0.67
embB 4247881 c.1368G>C synonymous_variant 0.67
embB 4247887 c.1374C>T synonymous_variant 0.67
embB 4247893 c.1380C>T synonymous_variant 0.67
embB 4247897 p.Met462Val missense_variant 0.67
embB 4247905 c.1392G>A synonymous_variant 1.0
embB 4247914 c.1401G>C synonymous_variant 1.0
embB 4247916 p.Arg468His missense_variant 1.0
embB 4247920 c.1407T>C synonymous_variant 1.0
embB 4247940 p.Leu476Trp missense_variant 1.0
embB 4247945 c.1432T>C synonymous_variant 1.0
embB 4247951 p.Ser480Ala missense_variant 1.0
embB 4247957 p.Met482Leu missense_variant 1.0
embB 4247965 c.1452C>G synonymous_variant 1.0
embB 4247971 c.1458C>T synonymous_variant 1.0
embB 4247972 p.Thr487Ser missense_variant 1.0
embB 4247983 c.1470G>C synonymous_variant 1.0
embB 4248007 c.1494C>T synonymous_variant 1.0
aftB 4267858 p.Ile327Val missense_variant 1.0
aftB 4269051 c.-215C>T upstream_gene_variant 1.0
aftB 4269060 c.-224G>C upstream_gene_variant 1.0
ubiA 4269075 p.Ile253Val missense_variant 1.0