TB-Profiler result

Run: ERR4815225
Summary

Run ID: ERR4815225

Sample name:

Date: 01-04-2023 13:44:36

Number of reads: 357307

Percentage reads mapped: 33.82

Strain: lineage1.2.2

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage1 Indo-Oceanic EAI RD239 1.0
lineage1.2.2 Indo-Oceanic EAI1 RD239 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.5 rifampicin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.7 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5075 c.-165C>T upstream_gene_variant 1.0
gyrB 6112 p.Met291Ile missense_variant 1.0
gyrB 6918 p.His560Arg missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8452 p.Ala384Val missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 0.86
gyrA 9564 p.Tyr755Asn missense_variant 0.18
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759656 c.-151A>C upstream_gene_variant 0.33
rpoB 761051 c.1245G>C synonymous_variant 0.4
rpoB 761054 c.1248G>C synonymous_variant 0.6
rpoB 761057 c.1251G>C synonymous_variant 0.4
rpoB 761060 c.1254C>G synonymous_variant 0.6
rpoB 761084 c.1278C>A synonymous_variant 0.33
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.5
rpoB 761096 c.1290G>C synonymous_variant 0.5
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.33
rpoB 761102 c.1296A>G synonymous_variant 0.6
rpoB 761132 c.1326G>C synonymous_variant 0.4
rpoB 761133 c.1327T>C synonymous_variant 0.5
rpoB 761534 c.1728G>C synonymous_variant 0.38
rpoB 761537 c.1731C>G synonymous_variant 0.38
rpoB 761557 p.Ala584Gly missense_variant 0.3
rpoB 761561 c.1755C>G synonymous_variant 0.2
rpoB 761562 p.Ala586Ser missense_variant 0.3
rpoB 761565 p.Met587Leu missense_variant 0.3
rpoB 761570 c.1764T>C synonymous_variant 0.33
rpoB 761600 c.1794T>C synonymous_variant 0.45
rpoB 761612 c.1806G>C synonymous_variant 0.5
rpoB 761615 c.1809A>C synonymous_variant 0.5
rpoB 761618 c.1812C>T synonymous_variant 0.22
rpoB 761633 c.1827G>C synonymous_variant 0.4
rpoB 761642 c.1836G>C synonymous_variant 0.4
rpoB 761643 p.Val613Ile missense_variant 0.33
rpoB 761648 c.1842T>C synonymous_variant 0.4
rpoB 761649 p.Ser615Pro missense_variant 0.4
rpoB 761654 p.Glu616Asp missense_variant 0.5
rpoB 762051 p.His749Tyr missense_variant 0.4
rpoB 762057 p.Ile751Val missense_variant 0.5
rpoB 762062 c.2256T>C synonymous_variant 0.5
rpoB 762065 c.2259T>C synonymous_variant 0.5
rpoB 762080 c.2274G>C synonymous_variant 0.5
rpoB 762085 p.Ala760Glu missense_variant 0.5
rpoB 762089 c.2283G>A synonymous_variant 0.5
rpoB 762233 c.2427G>C synonymous_variant 0.22
rpoB 762234 p.Pro810Ser missense_variant 0.22
rpoB 762239 c.2433G>A synonymous_variant 0.25
rpoB 762245 c.2439G>C synonymous_variant 0.25
rpoB 762254 c.2448T>C synonymous_variant 0.29
rpoB 762313 p.Gly836Asp missense_variant 0.2
rpoB 762731 p.Gln975His missense_variant 0.18
rpoC 762902 c.-468C>T upstream_gene_variant 0.33
rpoC 762911 c.-459C>T upstream_gene_variant 0.38
rpoC 762917 c.-453C>T upstream_gene_variant 0.33
rpoC 762920 c.-450C>T upstream_gene_variant 0.33
rpoC 762929 c.-441G>T upstream_gene_variant 0.33
rpoC 762944 c.-426C>T upstream_gene_variant 0.27
rpoC 762956 c.-414G>T upstream_gene_variant 0.23
rpoC 762962 c.-408C>T upstream_gene_variant 0.23
rpoC 762983 c.-387C>T upstream_gene_variant 0.22
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 0.42
rpoC 763043 c.-327G>C upstream_gene_variant 0.53
rpoC 763053 c.-317T>C upstream_gene_variant 0.62
rpoC 763067 c.-303C>G upstream_gene_variant 0.21
rpoC 763070 c.-300T>C upstream_gene_variant 0.64
rpoB 763077 p.Val1091Thr missense_variant 0.6
rpoC 763103 c.-267G>C upstream_gene_variant 0.6
rpoC 763109 c.-261C>T upstream_gene_variant 0.18
rpoC 763115 c.-255T>C upstream_gene_variant 0.56
rpoB 763119 p.Asn1105Asp missense_variant 0.5
rpoC 763127 c.-243G>C upstream_gene_variant 0.46
rpoC 763133 c.-237G>C upstream_gene_variant 0.4
rpoC 763492 c.123G>C synonymous_variant 0.22
rpoC 763528 c.159G>C synonymous_variant 0.25
rpoC 763531 c.162G>C synonymous_variant 0.25
rpoC 763534 c.165T>C synonymous_variant 0.25
rpoC 763537 c.168C>G synonymous_variant 0.25
rpoC 763546 c.177A>G synonymous_variant 0.29
rpoC 763550 p.Tyr61Ala missense_variant 0.29
rpoC 763570 c.201G>C synonymous_variant 0.44
rpoC 763578 p.Phe70Tyr missense_variant 0.3
rpoC 763585 c.216C>G synonymous_variant 0.18
rpoC 763589 p.Ile74Val missense_variant 0.45
rpoC 763603 c.234C>T synonymous_variant 0.14
rpoC 763606 c.237C>A synonymous_variant 0.21
rpoC 763609 c.240C>T synonymous_variant 0.2
rpoC 763615 c.246G>C synonymous_variant 0.42
rpoC 763618 c.249C>G synonymous_variant 0.27
rpoC 763619 p.Arg84Ser missense_variant 0.29
rpoC 763622 p.Ala85Ser missense_variant 0.25
rpoC 763636 c.267T>C synonymous_variant 0.29
rpoC 763642 c.273G>C synonymous_variant 0.47
rpoC 763647 p.Gly93Ala missense_variant 0.22
rpoC 763654 c.285C>T synonymous_variant 0.12
rpoC 763655 p.Glu96Lys missense_variant 0.14
rpoC 763660 c.291T>C synonymous_variant 0.29
rpoC 763666 c.297G>C synonymous_variant 0.15
rpoC 763669 c.300C>G synonymous_variant 0.19
rpoC 763672 c.303C>G synonymous_variant 0.12
rpoC 763674 p.Thr102Arg missense_variant 0.12
rpoC 763699 c.330G>T synonymous_variant 0.5
rpoC 763708 c.339G>C synonymous_variant 0.45
rpoC 763714 c.345G>C synonymous_variant 0.57
rpoC 763717 c.348T>C synonymous_variant 0.54
rpoC 763718 p.Leu117Val missense_variant 0.54
rpoC 763723 c.354G>C synonymous_variant 0.43
rpoC 763724 p.Asp119Asn missense_variant 0.36
rpoC 763729 c.360G>C synonymous_variant 0.46
rpoC 763732 c.363C>G synonymous_variant 0.45
rpoC 763735 c.366G>C synonymous_variant 0.46
rpoC 763744 c.375G>C synonymous_variant 0.46
rpoC 763747 c.378G>A synonymous_variant 0.15
rpoC 763751 p.Ile128Val missense_variant 0.58
rpoC 763772 p.Val135Met missense_variant 0.33
rpoC 763884 p.Ala172Val missense_variant 1.0
rpoC 763886 c.517C>A synonymous_variant 1.0
rpoC 764573 p.Leu402Ile missense_variant 0.5
rpoC 764578 c.1209C>G synonymous_variant 0.67
rpoC 764581 c.1212T>C synonymous_variant 0.67
rpoC 764582 p.Leu405Met missense_variant 0.67
rpoC 764602 c.1233C>T synonymous_variant 0.43
rpoC 764605 c.1236G>T synonymous_variant 0.43
rpoC 764611 c.1242G>T synonymous_variant 0.5
rpoC 764647 c.1278C>T synonymous_variant 0.5
rpoC 764650 c.1281G>T synonymous_variant 0.33
rpoC 764653 c.1284G>C synonymous_variant 0.43
rpoC 764656 c.1287C>T synonymous_variant 0.43
rpoC 764662 c.1293G>C synonymous_variant 0.33
rpoC 764677 c.1308C>G synonymous_variant 0.33
rpoC 764678 p.Lys437Gln missense_variant 0.33
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781754 c.195G>A synonymous_variant 0.33
rpsL 781760 c.201T>C synonymous_variant 0.38
rpsL 781766 c.207C>T synonymous_variant 0.22
rpsL 781772 c.213C>T synonymous_variant 0.22
rpsL 781796 p.Met79Ile missense_variant 0.43
rpsL 781802 c.243G>C synonymous_variant 0.29
rpsL 781805 c.246G>T synonymous_variant 0.29
rpsL 781811 c.252C>T synonymous_variant 0.33
rpsL 781814 c.255C>T synonymous_variant 0.29
rpsL 781817 c.258G>T synonymous_variant 0.29
rpsL 781829 c.270G>C synonymous_variant 0.5
rpsL 781832 c.273T>C synonymous_variant 0.5
rpsL 781838 c.279G>T synonymous_variant 0.5
fbiC 1303217 p.Arg96Pro missense_variant 0.33
fbiC 1305082 p.His718Tyr missense_variant 1.0
fbiC 1305151 p.Pro741Ser missense_variant 0.25
Rv1258c 1406129 p.Asp404Glu missense_variant 0.15
embR 1417019 p.Cys110Tyr missense_variant 1.0
embR 1417403 c.-56G>A upstream_gene_variant 0.4
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.33
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.43
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.5
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.2
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.18
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.42
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.4
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.4
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.97
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.51
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.55
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.55
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.47
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.87
rrs 1472256 n.411T>C non_coding_transcript_exon_variant 0.17
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.28
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 1.0
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 1.0
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 1.0
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.75
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 1.0
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 1.0
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.75
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 1.0
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.94
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.94
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.95
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.96
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.96
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.96
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.91
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.97
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.95
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.15
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 1.0
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.94
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.94
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.48
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 1.0
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.67
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.75
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.38
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.71
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.26
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.71
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.7
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.7
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.19
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.67
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.31
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.68
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.67
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.91
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.67
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.92
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.9
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.34
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.53
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.33
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.91
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.94
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.92
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.92
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.47
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.39
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.87
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.31
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.39
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.97
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.94
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.94
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.92
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.18
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.21
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.93
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.92
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.83
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.74
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.91
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.91
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.91
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.52
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.79
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.38
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.45
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.96
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.98
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.52
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.5
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.2
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.18
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.18
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.18
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.6
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.96
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.12
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.95
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.14
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 1.0
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.85
rrs 1473293 n.1449delA non_coding_transcript_exon_variant 1.0
rrs 1473293 n.1449A>G non_coding_transcript_exon_variant 1.0
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.83
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 1.0
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 1.0
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.22
rrl 1473384 n.-274A>G upstream_gene_variant 0.78
rrl 1473390 n.-268A>C upstream_gene_variant 1.0
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 1.0
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 1.0
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 1.0
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.21
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.21
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.5
rrl 1474272 n.615C>T non_coding_transcript_exon_variant 0.5
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 1.0
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 1.0
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 1.0
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 1.0
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 1.0
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 1.0
rrl 1474588 n.931A>G non_coding_transcript_exon_variant 0.25
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.5
rrl 1474629 n.972G>T non_coding_transcript_exon_variant 0.25
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.5
rrl 1474634 n.977T>G non_coding_transcript_exon_variant 0.5
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 1.0
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.43
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474638 n.981C>T non_coding_transcript_exon_variant 1.0
rrl 1474652 n.995T>G non_coding_transcript_exon_variant 0.4
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.75
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 1.0
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.67
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.5
rrl 1474715 n.1060_1061delAA non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>C non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474765 n.1108A>G non_coding_transcript_exon_variant 0.5
rrl 1474774 n.1117A>G non_coding_transcript_exon_variant 0.5
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.75
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.4
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.4
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 1.0
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.4
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1475031 n.1374G>C non_coding_transcript_exon_variant 1.0
rrl 1475059 n.1403_1404insTA non_coding_transcript_exon_variant 1.0
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 1.0
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 1.0
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 1.0
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 1.0
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 1.0
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 1.0
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 1.0
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 1.0
rrl 1475879 n.2222T>C non_coding_transcript_exon_variant 0.2
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.4
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 1.0
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.89
rrl 1475892 n.2235A>C non_coding_transcript_exon_variant 0.44
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.43
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 1.0
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 1.0
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.33
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.5
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.5
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.43
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.4
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 1.0
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 1.0
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.5
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.5
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 1.0
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.5
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.75
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.5
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.75
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.75
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 1.0
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.36
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.19
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.15
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.72
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.17
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.82
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.16
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.13
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.78
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.66
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.63
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.91
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.69
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.83
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.4
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.75
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 1.0
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 1.0
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.5
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.75
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 1.0
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 1.0
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.4
rrl 1476573 n.2916A>G non_coding_transcript_exon_variant 0.25
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.56
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.89
rrl 1476600 n.2943A>C non_coding_transcript_exon_variant 0.44
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.6
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.9
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.8
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.6
rrl 1476624 n.2967T>C non_coding_transcript_exon_variant 0.2
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.88
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.9
rrl 1476633 n.2976A>G non_coding_transcript_exon_variant 0.8
rrl 1476645 n.2988A>G non_coding_transcript_exon_variant 0.22
rrl 1476664 n.3007T>A non_coding_transcript_exon_variant 0.75
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 0.67
rrl 1476675 n.3018C>A non_coding_transcript_exon_variant 0.67
inhA 1674658 p.Arg153Trp missense_variant 0.33
rpsA 1833661 c.120A>G synonymous_variant 0.18
rpsA 1833667 c.126C>T synonymous_variant 0.2
rpsA 1833668 p.Ile43Val missense_variant 0.2
rpsA 1833676 c.135A>G synonymous_variant 0.2
rpsA 1833679 c.138G>C synonymous_variant 0.18
rpsA 1833694 c.153G>C synonymous_variant 0.3
rpsA 1833721 c.180A>G synonymous_variant 0.33
rpsA 1833727 c.186G>C synonymous_variant 0.5
rpsA 1833732 p.Pro64Leu missense_variant 0.4
rpsA 1833736 c.195C>T synonymous_variant 0.67
rpsA 1833742 c.201A>G synonymous_variant 0.67
rpsA 1834195 c.654G>C synonymous_variant 0.45
rpsA 1834228 c.687C>T synonymous_variant 0.4
rpsA 1834234 c.693G>C synonymous_variant 0.55
rpsA 1834240 c.699T>C synonymous_variant 0.5
rpsA 1834246 c.705G>T synonymous_variant 0.6
rpsA 1834249 c.708T>C synonymous_variant 0.67
rpsA 1834261 c.720A>G synonymous_variant 0.56
rpsA 1834264 c.723G>C synonymous_variant 0.53
rpsA 1834294 c.753G>C synonymous_variant 0.29
rpsA 1834298 p.Gln253Glu missense_variant 0.3
rpsA 1834306 c.765T>C synonymous_variant 0.17
rpsA 1834307 p.Asp256Gln missense_variant 0.25
rpsA 1834312 c.771G>A synonymous_variant 0.23
rpsA 1834327 c.786G>T synonymous_variant 0.23
rpsA 1834330 c.789C>G synonymous_variant 0.15
rpsA 1834348 c.807T>C synonymous_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2156140 c.-29C>A upstream_gene_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168616 p.Gln666Arg missense_variant 1.0
PPE35 2168742 p.Gly624Asp missense_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2518299 p.Gly62Val missense_variant 0.2
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
folC 2746251 p.Ala450Thr missense_variant 0.27
folC 2746831 c.768G>T synonymous_variant 0.29
Rv2752c 3064889 p.Lys435Glu missense_variant 1.0
Rv2752c 3065155 c.1036delG frameshift_variant 0.5
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339609 c.492G>A synonymous_variant 0.2
Rv3083 3448656 c.153G>T synonymous_variant 0.33
Rv3083 3448714 p.Asp71His missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474597 c.591C>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
fbiB 3641932 p.Arg133His missense_variant 0.13
fbiB 3642107 c.573G>A synonymous_variant 0.2
alr 3841518 c.-98C>T upstream_gene_variant 0.33
alr 3841546 c.-126C>A upstream_gene_variant 1.0
ddn 3987081 p.Gly80Cys missense_variant 0.4
clpC1 4040517 p.Val63Ala missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4241042 p.Asn394Asp missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4245674 c.-840A>C upstream_gene_variant 1.0
embA 4245969 p.Pro913Ser missense_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4248720 p.Gly736Asp missense_variant 0.14
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269495 c.-659G>A upstream_gene_variant 0.2
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ethA 4326439 p.Asn345Lys missense_variant 1.0
ethR 4326691 c.-858C>T upstream_gene_variant 0.15
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0
whiB6 4338635 c.-114A>C upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407873 c.330G>T synonymous_variant 1.0