TB-Profiler result

Run: SRR15315871
Summary

Run ID: SRR15315871

Sample name:

Date: 03-04-2023 12:55:06

Number of reads: 314249

Percentage reads mapped: 4.0

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 762863 c.-507T>C upstream_gene_variant 0.89
rpoB 762870 p.Met1022Val missense_variant 0.9
rpoB 762878 p.Ile1024Met missense_variant 0.91
rpoB 762879 p.Met1025Leu missense_variant 0.91
rpoC 762899 c.-471G>C upstream_gene_variant 0.93
rpoB 762925 p.Thr1040Ile missense_variant 0.89
rpoC 762929 c.-441G>C upstream_gene_variant 0.89
rpoB 762939 p.Met1045Leu missense_variant 0.89
rpoB 762942 p.Ile1046Val missense_variant 0.89
rpoC 762980 c.-390T>C upstream_gene_variant 0.83
rpoC 762983 c.-387C>A upstream_gene_variant 0.93
rpoC 762989 c.-381G>C upstream_gene_variant 0.87
rpoC 762998 c.-372G>A upstream_gene_variant 0.87
rpoB 763005 p.Cys1067Val missense_variant 0.8
rpoC 763013 c.-357C>T upstream_gene_variant 0.75
rpoB 763014 p.Met1070Leu missense_variant 0.75
rpoB 763017 p.Gln1071Glu missense_variant 0.75
rpoC 763022 c.-348C>T upstream_gene_variant 0.75
rpoC 763028 c.-342T>C upstream_gene_variant 0.75
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 764857 c.1488G>C synonymous_variant 1.0
rpoC 764858 p.Leu497Met missense_variant 1.0
rpoC 764869 c.1500C>T synonymous_variant 1.0
rpoC 764872 c.1503A>T synonymous_variant 1.0
rpoC 764878 c.1509C>G synonymous_variant 1.0
rpoC 764887 c.1518G>A synonymous_variant 1.0
rpoC 764888 c.1519T>C synonymous_variant 1.0
rpoC 764893 c.1524T>C synonymous_variant 1.0
rpoC 764911 c.1542A>C synonymous_variant 1.0
rpoC 764914 p.Met515Ile missense_variant 1.0
rpoC 764918 p.Val517Ile missense_variant 1.0
rpoC 764935 c.1566T>C synonymous_variant 1.0
rpoC 764948 c.1579_1581delTTGinsCTC synonymous_variant 1.0
rpoC 764953 c.1584G>C synonymous_variant 1.0
rpoC 764956 c.1587T>C synonymous_variant 1.0
rpoC 764958 p.Glu530Ala missense_variant 1.0
rpoC 764962 c.1593G>C synonymous_variant 1.0
rpoC 764968 c.1599T>C synonymous_variant 1.0
rpoC 764995 c.1626C>T synonymous_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
fbiC 1303906 p.Gly326Cys missense_variant 1.0
rrs 1471892 n.47G>A non_coding_transcript_exon_variant 1.0
rrs 1471896 n.51T>C non_coding_transcript_exon_variant 1.0
rrs 1471898 n.53A>T non_coding_transcript_exon_variant 1.0
rrs 1472135 n.290C>T non_coding_transcript_exon_variant 1.0
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 1.0
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 1.0
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.78
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472181 n.336G>A non_coding_transcript_exon_variant 0.69
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 1.0
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.45
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.58
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 1.0
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.36
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.64
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 1.0
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 1.0
rrs 1472252 n.407G>A non_coding_transcript_exon_variant 1.0
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 1.0
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472349 n.504A>T non_coding_transcript_exon_variant 1.0
rrs 1472374 n.529T>A non_coding_transcript_exon_variant 0.5
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.5
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.5
rrs 1472390 n.545T>C non_coding_transcript_exon_variant 0.67
rrs 1472391 n.546C>T non_coding_transcript_exon_variant 0.83
rrs 1472412 n.567A>C non_coding_transcript_exon_variant 0.67
rrs 1472415 n.570T>G non_coding_transcript_exon_variant 0.75
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.67
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.62
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.57
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.87
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.25
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.23
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.85
rrs 1472785 n.940G>T non_coding_transcript_exon_variant 0.25
rrs 1472786 n.941C>G non_coding_transcript_exon_variant 0.25
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.78
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.57
rrs 1472812 n.967A>C non_coding_transcript_exon_variant 0.33
rrs 1472887 n.1042G>C non_coding_transcript_exon_variant 0.8
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.82
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.93
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.93
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.93
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.93
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.93
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.93
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 1.0
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 1.0
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 1.0
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 1.0
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 1.0
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 1.0
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 1.0
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 1.0
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 1.0
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.67
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.6
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.5
rrs 1473164 n.1319C>G non_coding_transcript_exon_variant 0.5
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.6
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.8
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 1.0
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 1.0
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.67
rrl 1475791 n.2134A>G non_coding_transcript_exon_variant 0.67
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.8
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.8
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.86
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.86
rrl 1476022 n.2365A>G non_coding_transcript_exon_variant 0.67
rrl 1476025 n.2368G>A non_coding_transcript_exon_variant 0.67
rrl 1476238 n.2581T>C non_coding_transcript_exon_variant 0.86
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.98
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.99
rrl 1476266 n.2609G>A non_coding_transcript_exon_variant 1.0
rrl 1476279 n.2622G>C non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 1.0
rrl 1476281 n.2624T>A non_coding_transcript_exon_variant 1.0
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 1.0
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 1.0
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 1.0
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 1.0
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 1.0
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 1.0
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 1.0
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.97
rrl 1476339 n.2682G>A non_coding_transcript_exon_variant 0.77
rrl 1476356 n.2699C>T non_coding_transcript_exon_variant 1.0
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.18
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 1.0
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.19
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 1.0
rrl 1476384 n.2727G>A non_coding_transcript_exon_variant 1.0
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 1.0
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 1.0
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.21
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 1.0
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 1.0
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.99
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.99
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.98
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.85
rrl 1476501 n.2844C>T non_coding_transcript_exon_variant 0.99
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 1.0
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 1.0
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 1.0
rrl 1476521 n.2864C>T non_coding_transcript_exon_variant 1.0
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 1.0
rrl 1476525 n.2868A>C non_coding_transcript_exon_variant 1.0
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 1.0
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 1.0
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 1.0
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 1.0
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 1.0
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 1.0
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 1.0
rrl 1476584 n.2927C>G non_coding_transcript_exon_variant 1.0
rrl 1476588 n.2931A>T non_coding_transcript_exon_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2859830 p.Gly197Trp missense_variant 1.0
rpoA 3878390 p.Arg40Cys missense_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0