TB-Profiler result

Run: SRR6046834
Summary

Run ID: SRR6046834

Sample name:

Date: 04-04-2023 12:23:58

Number of reads: 26468

Percentage reads mapped: 1.54

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 761537 c.1731C>G synonymous_variant 1.0
rpoB 761570 c.1764T>C synonymous_variant 1.0
rpoB 761573 c.1767C>G synonymous_variant 1.0
rpoB 761579 c.1773G>C synonymous_variant 1.0
rpoB 761606 c.1800C>G synonymous_variant 1.0
rpoC 762896 c.-474G>C upstream_gene_variant 0.83
rpoC 762917 c.-453C>G upstream_gene_variant 0.94
rpoC 762923 c.-447C>G upstream_gene_variant 0.94
rpoB 762925 p.Thr1040Ile missense_variant 0.94
rpoC 762929 c.-441G>C upstream_gene_variant 0.94
rpoB 762939 p.Met1045Leu missense_variant 0.94
rpoB 762942 p.Ile1046Val missense_variant 0.94
rpoC 762965 c.-405T>C upstream_gene_variant 0.94
rpoC 762980 c.-390T>C upstream_gene_variant 0.94
rpoC 762989 c.-381G>C upstream_gene_variant 0.94
rpoC 762995 c.-375G>T upstream_gene_variant 0.94
rpoB 763005 p.Cys1067Val missense_variant 0.93
rpoC 763013 c.-357C>G upstream_gene_variant 0.92
rpoB 763014 p.Met1070Leu missense_variant 0.92
rpoB 763017 p.Gln1071Glu missense_variant 0.92
rpoC 763028 c.-342T>C upstream_gene_variant 1.0
rpoC 763031 c.-339T>G upstream_gene_variant 1.0
rpoC 763040 c.-330C>G upstream_gene_variant 1.0
rpoB 763050 p.Leu1082Met missense_variant 1.0
rpoC 764428 c.1059G>C synonymous_variant 1.0
rpoC 764431 c.1062G>C synonymous_variant 1.0
rpoC 764434 c.1065A>G synonymous_variant 1.0
rpoC 764435 c.1066A>C synonymous_variant 1.0
rpoC 764446 p.Asp359Glu missense_variant 1.0
rpoC 764450 p.Gly361Arg missense_variant 1.0
rpoC 764461 p.Glu364Asp missense_variant 1.0
rpoC 764468 p.Val367Ile missense_variant 1.0
rpoC 764471 p.Asn368Arg missense_variant 1.0
rpoC 764485 c.1116G>C synonymous_variant 1.0
rpoC 764491 c.1122G>T synonymous_variant 1.0
rpoC 764497 c.1128A>G synonymous_variant 1.0
rpoC 764498 p.Ser377Ala missense_variant 1.0
rpoC 764506 c.1137C>T synonymous_variant 1.0
rpoC 764587 c.1218C>G synonymous_variant 1.0
rpoC 764605 c.1236G>C synonymous_variant 1.0
rpoC 764611 c.1242G>C synonymous_variant 1.0
rpoC 764632 c.1263T>C synonymous_variant 1.0
rpoC 764650 c.1281G>C synonymous_variant 1.0
rpoC 764672 p.Gln435Glu missense_variant 1.0
rpoC 764677 c.1308C>G synonymous_variant 1.0
rpoC 764695 c.1326T>C synonymous_variant 1.0
rpoC 764701 c.1332C>G synonymous_variant 1.0
rpoC 764705 p.Leu446Lys missense_variant 1.0
rpoC 764716 c.1347G>C synonymous_variant 1.0
rpoC 764858 p.Leu497Met missense_variant 1.0
rpoC 764872 c.1503A>G synonymous_variant 1.0
rpoC 764875 c.1506C>G synonymous_variant 1.0
rpoC 764878 c.1509C>G synonymous_variant 0.67
rpoC 764888 c.1519T>C synonymous_variant 1.0
rpoC 764893 c.1524T>C synonymous_variant 1.0
rpoC 764902 c.1533C>G synonymous_variant 1.0
rpoC 764911 c.1542A>G synonymous_variant 1.0
rpoC 764913 p.Met515Lys missense_variant 0.67
rpoC 764918 p.Val517Ile missense_variant 1.0
rpoC 764923 c.1554A>G synonymous_variant 0.67
rpoC 764932 c.1563C>G synonymous_variant 0.67
rpoC 764935 c.1566T>C synonymous_variant 1.0
rpoC 764941 c.1572G>C synonymous_variant 0.67
rpoC 764948 c.1579T>C synonymous_variant 1.0
rpoC 764953 c.1584G>C synonymous_variant 1.0
rpoC 764956 c.1587T>C synonymous_variant 1.0
rpoC 764958 p.Glu530Ala missense_variant 1.0
rpoC 764968 c.1599T>C synonymous_variant 1.0
rpoC 764983 c.1614T>C synonymous_variant 0.67
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.9
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.92
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 0.92
rrs 1472129 n.284G>A non_coding_transcript_exon_variant 0.92
rrs 1472135 n.290C>T non_coding_transcript_exon_variant 0.92
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.92
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.92
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.92
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.92
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 0.92
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.96
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 1.0
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 1.0
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 1.0
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 1.0
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 1.0
rrs 1472266 n.421C>A non_coding_transcript_exon_variant 1.0
rrs 1472333 n.488G>T non_coding_transcript_exon_variant 1.0
rrs 1472338 n.493A>C non_coding_transcript_exon_variant 1.0
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472349 n.504A>T non_coding_transcript_exon_variant 1.0
rrs 1472374 n.529T>A non_coding_transcript_exon_variant 1.0
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 1.0
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 1.0
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 1.0
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 1.0
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 1.0
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 1.0
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 1.0
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 1.0
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 1.0
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 1.0
rrs 1472812 n.967A>C non_coding_transcript_exon_variant 1.0
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 1.0
rrl 1474875 n.1218G>A non_coding_transcript_exon_variant 1.0
rrl 1474876 n.1219T>A non_coding_transcript_exon_variant 1.0
rrl 1474883 n.1226T>C non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>G non_coding_transcript_exon_variant 1.0
rrl 1476356 n.2699C>G non_coding_transcript_exon_variant 1.0
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 1.0
rrl 1476384 n.2727G>C non_coding_transcript_exon_variant 1.0
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 1.0
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 1.0
rrl 1476428 n.2771C>A non_coding_transcript_exon_variant 1.0
rrl 1476443 n.2786G>C non_coding_transcript_exon_variant 1.0
rrl 1476455 n.2798C>G non_coding_transcript_exon_variant 1.0
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 1.0
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 1.0
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 1.0