TB-Profiler result

Run: ERR10796573
Summary

Run ID: ERR10796573

Sample name:

Date: 31-03-2023 11:11:44

Number of reads: 3151034

Percentage reads mapped: 99.99

Strain: lineage4.8

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.67 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.38
ccsA 620281 p.Arg131Ser missense_variant 0.14
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.28
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.35
rrs 1472141 n.296G>A non_coding_transcript_exon_variant 0.43
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.47
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.47
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.47
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 0.44
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.27
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.26
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.11
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.19
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.19
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.33
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.39
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.43
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.42
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.47
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.49
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.48
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.48
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.47
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.47
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.48
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.45
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.23
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.12
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.39
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.6
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.62
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.7
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.68
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.68
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.66
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.64
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.35
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.15
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.11
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.1
rrl 1475706 n.2049A>C non_coding_transcript_exon_variant 0.1
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.12
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 0.31
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.36
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.34
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 0.33
rrl 1475772 n.2115A>C non_coding_transcript_exon_variant 0.38
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.4
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.12
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.41
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.42
rrl 1475892 n.2235A>G non_coding_transcript_exon_variant 0.38
rrl 1475897 n.2240T>G non_coding_transcript_exon_variant 0.35
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.36
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.38
rrl 1475900 n.2243A>C non_coding_transcript_exon_variant 0.36
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.36
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.35
rrl 1475938 n.2281C>A non_coding_transcript_exon_variant 0.25
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.27
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.23
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.16
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.7
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.74
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.82
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.85
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.89
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.88
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.89
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.89
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.91
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.91
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.91
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.94
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.82
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.74
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.68
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.57
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.55
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fbiD 3339740 p.Ala208Glu missense_variant 0.25
fbiD 3339746 p.Ala210Gly missense_variant 0.27
clpC1 4039729 p.Asp326Asn missense_variant 1.0
embA 4242526 c.-707C>G upstream_gene_variant 0.21
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246688 p.Pro59Ser missense_variant 0.12
embB 4248324 p.Ala604Gly missense_variant 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 1.0