TB-Profiler result

Run: ERR4818787
Summary

Run ID: ERR4818787

Sample name:

Date: 01-04-2023 15:45:03

Number of reads: 562812

Percentage reads mapped: 59.33

Strain: lineage6

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage6 West-Africa 2 AFRI_1 RD702 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.18 rifampicin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.87 streptomycin
katG 2154234 c.1877delT frameshift_variant 0.18 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 6934 c.-368A>G upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8493 p.Leu398Phe missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491668 p.Lys296Glu missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
ccsA 619912 c.23_24delTC frameshift_variant 0.15
rpoB 760855 p.Thr350Ile missense_variant 1.0
rpoB 760969 p.Ser388Leu missense_variant 1.0
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.14
rpoB 761096 c.1290G>C synonymous_variant 0.13
rpoB 761102 c.1296A>G synonymous_variant 0.13
rpoB 761132 c.1326G>C synonymous_variant 0.18
rpoB 761133 c.1327T>C synonymous_variant 0.18
rpoB 761723 p.Glu639Asp missense_variant 1.0
rpoB 761826 p.His674Asp missense_variant 0.13
rpoB 762194 c.2388G>C synonymous_variant 0.25
rpoB 762200 c.2394C>T synonymous_variant 0.17
rpoB 762218 c.2412T>C synonymous_variant 0.27
rpoB 762233 c.2427G>C synonymous_variant 0.2
rpoB 762234 p.Pro810Ser missense_variant 0.2
rpoB 762239 c.2433G>A synonymous_variant 0.25
rpoB 762245 c.2439G>C synonymous_variant 0.25
rpoB 762248 c.2442G>C synonymous_variant 0.25
rpoB 762254 c.2448T>C synonymous_variant 0.25
rpoC 762926 c.-444C>G upstream_gene_variant 0.14
rpoC 762929 c.-441G>C upstream_gene_variant 0.14
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 0.2
rpoC 763043 c.-327G>C upstream_gene_variant 0.3
rpoC 763053 c.-317T>C upstream_gene_variant 0.33
rpoC 763067 c.-303C>G upstream_gene_variant 0.33
rpoC 763070 c.-300T>C upstream_gene_variant 0.33
rpoC 763076 c.-294C>T upstream_gene_variant 0.43
rpoB 763077 p.Val1091Thr missense_variant 0.43
rpoC 763103 c.-267G>C upstream_gene_variant 0.43
rpoC 763109 c.-261C>T upstream_gene_variant 0.38
rpoC 763115 c.-255T>C upstream_gene_variant 0.38
rpoB 763119 p.Asn1105Asp missense_variant 0.38
rpoC 763127 c.-243G>C upstream_gene_variant 0.29
rpoC 763133 c.-237G>C upstream_gene_variant 0.29
rpoC 763528 c.159G>C synonymous_variant 0.15
rpoC 763531 c.162G>C synonymous_variant 0.15
rpoC 763534 c.165T>C synonymous_variant 0.15
rpoC 763546 c.177A>G synonymous_variant 0.25
rpoC 763570 c.201G>C synonymous_variant 0.29
rpoC 763666 c.297G>C synonymous_variant 0.33
rpoC 763675 c.306C>G synonymous_variant 0.3
rpoC 763699 c.330G>T synonymous_variant 0.4
rpoC 763708 c.339G>C synonymous_variant 0.4
rpoC 763714 c.345G>C synonymous_variant 0.44
rpoC 763717 c.348T>C synonymous_variant 0.4
rpoC 763718 p.Leu117Val missense_variant 0.4
rpoC 763723 c.354G>C synonymous_variant 0.36
rpoC 763724 p.Asp119Asn missense_variant 0.36
rpoC 763729 c.360G>C synonymous_variant 0.3
rpoC 763732 c.363C>G synonymous_variant 0.36
rpoC 763735 c.366G>C synonymous_variant 0.46
rpoC 763744 c.375G>C synonymous_variant 0.43
rpoC 763751 p.Ile128Val missense_variant 0.38
rpoC 763772 p.Val135Met missense_variant 0.27
rpoC 764291 p.Ser308Pro missense_variant 0.18
rpoC 764485 c.1116G>C synonymous_variant 0.18
rpoC 764491 c.1122G>T synonymous_variant 0.18
rpoC 764497 c.1128A>G synonymous_variant 0.18
rpoC 764503 c.1134G>T synonymous_variant 0.18
rpoC 764509 c.1140G>C synonymous_variant 0.2
rpoC 764512 c.1143G>C synonymous_variant 0.2
rpoC 764521 c.1152T>C synonymous_variant 0.29
rpoC 764543 p.Thr392Ala missense_variant 0.22
rpoC 764656 c.1287C>T synonymous_variant 0.25
rpoC 764662 c.1293G>C synonymous_variant 0.25
rpoC 764677 c.1308C>G synonymous_variant 0.38
rpoC 764678 p.Lys437Gln missense_variant 0.38
rpoC 764706 p.Leu446Gln missense_variant 0.43
rpoC 764713 c.1344G>T synonymous_variant 0.43
rpoC 764731 c.1362G>C synonymous_variant 0.25
rpoC 764737 c.1368G>T synonymous_variant 0.25
rpoC 764746 c.1377G>C synonymous_variant 0.29
rpoC 764910 p.Pro514Leu missense_variant 0.25
rpoC 766231 c.2862T>C synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775994 p.Ile829Met missense_variant 0.17
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 778753 c.-273C>T upstream_gene_variant 0.22
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
fbiC 1303018 c.88C>T synonymous_variant 0.12
fbiC 1304582 p.Asn551Ser missense_variant 0.11
fbiC 1304902 p.Glu658Lys missense_variant 0.12
Rv1258c 1406685 p.Val219Ala missense_variant 1.0
embR 1416633 p.Leu239Val missense_variant 1.0
atpE 1460909 c.-136C>A upstream_gene_variant 0.4
atpE 1461251 c.207G>T synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.5
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.67
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.71
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.83
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.73
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.73
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.73
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.61
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.67
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.33
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.78
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.96
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.57
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.62
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 1.0
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 1.0
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 1.0
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 1.0
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.98
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.96
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.96
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.9
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.92
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.4
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.98
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.93
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.93
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.29
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.88
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.67
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.22
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.62
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.6
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.67
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.67
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.67
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.67
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.75
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.41
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.86
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.11
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.88
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.85
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.85
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.85
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.14
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.87
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.88
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 1.0
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.17
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.5
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.15
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.7
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.15
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.97
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.88
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.12
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.97
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.92
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.11
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.19
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.18
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.93
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.56
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.6
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.94
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.84
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.84
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.81
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.48
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.48
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.77
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.75
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.81
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.62
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.71
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.71
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.71
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.33
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.6
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.38
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.5
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.84
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.84
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.5
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.57
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.28
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.27
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.27
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.27
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.52
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.93
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.92
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.9
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.82
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.81
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.86
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.15
rrl 1473384 n.-274A>G upstream_gene_variant 0.4
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.4
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.4
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.4
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.56
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.56
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.6
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.5
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.6
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.82
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>C non_coding_transcript_exon_variant 0.5
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.6
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.71
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 1.0
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.67
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 1.0
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 1.0
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 1.0
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 1.0
rrl 1475172 n.1515A>G non_coding_transcript_exon_variant 1.0
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 0.5
rrl 1475715 n.2058G>A non_coding_transcript_exon_variant 0.5
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 0.5
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.5
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.43
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.6
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.6
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.75
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.75
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 1.0
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.75
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 1.0
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 1.0
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 1.0
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 1.0
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 1.0
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 1.0
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 1.0
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.2
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.13
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.97
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.97
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.82
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.64
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.69
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.8
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.61
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.71
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 1.0
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 1.0
rrl 1476600 n.2943A>C non_coding_transcript_exon_variant 1.0
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 1.0
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 1.0
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 1.0
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 1.0
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 1.0
rrl 1476633 n.2976A>G non_coding_transcript_exon_variant 1.0
inhA 1674434 p.Val78Ala missense_variant 1.0
rpsA 1833661 c.120A>G synonymous_variant 0.36
rpsA 1833667 c.126C>T synonymous_variant 0.42
rpsA 1833668 p.Ile43Val missense_variant 0.42
rpsA 1833676 c.135A>G synonymous_variant 0.55
rpsA 1833679 c.138G>C synonymous_variant 0.55
rpsA 1833684 p.Arg48His missense_variant 0.36
rpsA 1833688 c.147C>T synonymous_variant 0.18
rpsA 1833694 c.153G>C synonymous_variant 0.55
rpsA 1833700 c.159C>T synonymous_variant 0.27
rpsA 1833721 c.180A>G synonymous_variant 0.3
rpsA 1833724 c.183C>T synonymous_variant 0.23
rpsA 1833727 c.186G>C synonymous_variant 0.17
rpsA 1833732 p.Pro64Leu missense_variant 0.23
rpsA 1833734 p.Ala65Ser missense_variant 0.15
rpsA 1833742 c.201A>G synonymous_variant 0.25
rpsA 1834028 p.Pro163Ala missense_variant 0.12
rpsA 1834195 c.654G>C synonymous_variant 0.31
rpsA 1834213 c.672G>A synonymous_variant 0.18
rpsA 1834228 c.687C>T synonymous_variant 0.43
rpsA 1834234 c.693G>C synonymous_variant 0.43
rpsA 1834240 c.699T>C synonymous_variant 0.4
rpsA 1834246 c.705G>T synonymous_variant 0.46
rpsA 1834249 c.708T>C synonymous_variant 0.55
rpsA 1834261 c.720A>G synonymous_variant 0.5
rpsA 1834264 c.723G>C synonymous_variant 0.5
rpsA 1834294 c.753G>C synonymous_variant 0.3
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918736 p.Glu266Gly missense_variant 0.22
ndh 2101956 p.Gln363Lys missense_variant 0.17
katG 2154066 c.2046T>C synonymous_variant 0.4
katG 2154604 p.Val503Ala missense_variant 0.29
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2155808 p.Phe102Leu missense_variant 0.12
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168463 p.Pro717Leu missense_variant 0.22
PPE35 2168964 p.Val550Ala missense_variant 0.2
PPE35 2169365 p.Ser416Arg missense_variant 0.18
PPE35 2169453 p.Tyr387Phe missense_variant 0.12
PPE35 2169602 c.1011C>A synonymous_variant 0.13
PPE35 2170709 c.-97A>G upstream_gene_variant 0.18
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223120 c.44dupG frameshift_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv1979c 2223363 c.-199A>G upstream_gene_variant 0.29
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2519281 c.1167G>T synonymous_variant 0.2
eis 2714909 p.Val142Leu missense_variant 0.12
folC 2747045 p.Asn185Ser missense_variant 0.17
thyX 3067265 c.681C>T synonymous_variant 0.22
thyX 3067872 c.73delT frameshift_variant 0.12
thyA 3074221 p.Ala84Gly missense_variant 0.17
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
fbiD 3339005 c.-113_-112insA upstream_gene_variant 0.11
Rv3083 3448990 p.Cys163Arg missense_variant 0.13
Rv3083 3449396 p.Cys298Tyr missense_variant 1.0
fprA 3473972 c.-35T>C upstream_gene_variant 0.11
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
Rv3236c 3612143 p.Arg325His missense_variant 1.0
fbiB 3642018 p.Asp162His missense_variant 0.11
clpC1 4038587 c.2118C>A synonymous_variant 0.25
clpC1 4039804 p.Ala301Ser missense_variant 0.75
clpC1 4039817 c.888A>T synonymous_variant 0.75
clpC1 4039820 c.885T>G synonymous_variant 0.75
clpC1 4039826 c.879C>G synonymous_variant 1.0
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 1.0
clpC1 4039838 p.Leu289Ile missense_variant 1.0
clpC1 4039865 c.840T>C synonymous_variant 0.43
clpC1 4039871 c.834C>G synonymous_variant 0.43
clpC1 4039875 p.Asn277Arg missense_variant 0.43
clpC1 4039889 c.816G>C synonymous_variant 0.33
clpC1 4039898 c.807C>G synonymous_variant 0.2
clpC1 4039910 c.795C>T synonymous_variant 0.2
clpC1 4039925 c.780C>G synonymous_variant 0.13
panD 4044432 c.-151T>G upstream_gene_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4241843 p.Leu661Ile missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embA 4244379 p.Pro383Ser missense_variant 1.0
embB 4246864 c.351C>T synonymous_variant 1.0
embB 4247487 p.Ser325Asn missense_variant 0.12
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4248311 p.Ala600Thr missense_variant 0.17
embB 4248726 p.Ser738Phe missense_variant 0.18
aftB 4267103 c.1734G>A synonymous_variant 0.25
aftB 4267599 p.Phe413Ser missense_variant 0.22
aftB 4269351 c.-515C>T upstream_gene_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269522 c.-686C>T upstream_gene_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
aftB 4269693 c.-857C>T upstream_gene_variant 1.0
ethA 4326465 p.Ile337Val missense_variant 1.0
ethA 4327086 p.Thr130Ala missense_variant 0.17
ethR 4327246 c.-303G>C upstream_gene_variant 0.12
ethR 4327767 c.220delA frameshift_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407669 p.Met178Ile missense_variant 0.29
gid 4408034 p.Glu57Lys missense_variant 1.0