TB-Profiler result

Run: SRR1140942
Summary

Run ID: SRR1140942

Sample name:

Date: 02-04-2023 20:59:24

Number of reads: 258511

Percentage reads mapped: 17.3

Strain:

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.97 streptomycin
tlyA 1918388 c.451delG frameshift_variant 0.25 capreomycin
pncA 2288841 c.400delG frameshift_variant 0.25 pyrazinamide
thyA 3074246 p.Gly76* stop_gained 0.29 para-aminosalicylic_acid
ethA 4326707 p.Trp256* stop_gained 0.25 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5072 c.-168G>T upstream_gene_variant 0.25
gyrB 5312 p.Ala25Ser missense_variant 0.33
gyrB 5555 p.Gly106Ser missense_variant 1.0
gyrB 5576 p.Ala113Thr missense_variant 0.75
gyrB 5830 p.Met197Ile missense_variant 0.4
gyrB 6001 c.762G>T synonymous_variant 0.4
gyrA 6397 c.-905G>A upstream_gene_variant 0.29
gyrB 6507 p.Ala423Glu missense_variant 0.29
gyrA 6901 c.-401G>A upstream_gene_variant 0.33
gyrB 7064 c.1827delG frameshift_variant 0.33
gyrA 7293 c.-9G>A upstream_gene_variant 0.4
gyrA 7324 p.Pro8His missense_variant 0.4
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7427 c.126G>A synonymous_variant 0.29
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7805 c.504C>T synonymous_variant 0.5
gyrA 7909 p.Trp203Leu missense_variant 0.67
gyrA 8163 p.Ala288Thr missense_variant 0.29
gyrA 8244 p.Val315Ile missense_variant 0.29
gyrA 8535 p.Glu412* stop_gained 0.4
gyrA 8553 p.Arg418Trp missense_variant 0.33
gyrA 8872 p.Gly524Val missense_variant 0.25
gyrA 8937 p.Gly546Arg missense_variant 0.29
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9380 p.Met693Ile missense_variant 0.29
gyrA 9468 p.Leu723Met missense_variant 0.4
gyrA 9509 c.2208G>A synonymous_variant 0.5
gyrA 9579 p.Gly760Arg missense_variant 0.25
fgd1 491238 c.456C>A synonymous_variant 0.25
fgd1 491279 p.Pro166His missense_variant 0.33
fgd1 491641 p.Ala287Ser missense_variant 0.67
fgd1 491671 p.Val297Leu missense_variant 0.67
mshA 575337 c.-11T>A upstream_gene_variant 0.5
mshA 575389 c.42C>A synonymous_variant 0.25
mshA 575419 c.72C>T synonymous_variant 0.29
mshA 575794 c.447C>T synonymous_variant 0.4
mshA 575801 p.His152Asn missense_variant 0.4
mshA 576162 p.Gly272Glu missense_variant 0.67
mshA 576203 p.Ala286Pro missense_variant 1.0
mshA 576217 p.Leu290Phe missense_variant 1.0
mshA 576342 p.Ser332Tyr missense_variant 0.67
mshA 576364 c.1017G>A synonymous_variant 0.67
mshA 576388 c.1041G>A synonymous_variant 0.67
ccsA 620625 p.Ile245Met missense_variant 1.0
ccsA 620644 p.Glu252* stop_gained 1.0
ccsA 620658 c.768C>A synonymous_variant 1.0
rpoB 760142 c.336C>A synonymous_variant 0.4
rpoB 760148 p.Asp114Glu missense_variant 0.4
rpoB 760268 p.Met154Ile missense_variant 0.33
rpoB 760408 p.Ser201Ile missense_variant 0.25
rpoB 760427 c.621G>A synonymous_variant 0.29
rpoB 760470 p.Arg222Ser missense_variant 0.29
rpoB 760580 p.Lys258Asn missense_variant 0.44
rpoB 760908 p.Gly368Cys missense_variant 0.29
rpoB 761015 c.1209G>T synonymous_variant 0.5
rpoB 761048 c.1242C>T synonymous_variant 0.4
rpoB 761486 c.1680C>A synonymous_variant 0.67
rpoC 762608 c.-762C>A upstream_gene_variant 0.67
rpoC 762665 c.-705G>A upstream_gene_variant 0.5
rpoC 762743 c.-627G>T upstream_gene_variant 1.0
rpoB 762841 p.Pro1012Leu missense_variant 0.5
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763112 p.Lys1102Asn missense_variant 0.22
rpoC 763400 p.Arg11Ser missense_variant 0.29
rpoC 763446 p.Gly26Asp missense_variant 0.33
rpoC 763492 c.123G>T synonymous_variant 0.29
rpoC 764621 p.Leu418Ile missense_variant 0.5
rpoC 765668 p.His767Asn missense_variant 0.33
rpoC 765932 p.Gly855Ser missense_variant 1.0
rpoC 766123 c.2754C>A synonymous_variant 0.5
rpoC 766653 p.Ser1095Tyr missense_variant 0.25
rpoC 766692 p.Gly1108Val missense_variant 0.25
rpoC 766694 p.Gln1109Lys missense_variant 0.25
rpoC 766723 c.3354G>T synonymous_variant 0.29
rpoC 766748 p.Pro1127Thr missense_variant 0.4
mmpL5 775717 c.2764C>A synonymous_variant 1.0
mmpL5 775932 p.Tyr850Phe missense_variant 0.22
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 0.8
mmpL5 776195 c.2286G>T synonymous_variant 0.4
mmpL5 776390 p.Asp697Glu missense_variant 0.25
mmpL5 776678 c.1803G>A synonymous_variant 0.33
mmpL5 776696 p.Pro595Gln missense_variant 0.29
mmpL5 776726 c.1754delT frameshift_variant 0.33
mmpL5 776742 c.1736_1738delGCC disruptive_inframe_deletion 0.33
mmpL5 777061 p.Ala474Ser missense_variant 0.5
mmpL5 777245 c.1236G>A synonymous_variant 0.67
mmpL5 777501 p.Thr327Ile missense_variant 0.4
mmpL5 777661 p.Ala274Thr missense_variant 0.4
mmpL5 777863 c.618G>A synonymous_variant 0.4
mmpL5 777932 p.Lys183Asn missense_variant 0.33
mmpR5 778211 c.-779C>A upstream_gene_variant 0.67
mmpL5 778229 p.Glu84Asp missense_variant 0.67
mmpS5 778927 c.-22C>T upstream_gene_variant 0.33
mmpR5 779159 p.Ala57Glu missense_variant 0.25
mmpR5 779167 p.Leu60Val missense_variant 0.22
mmpL5 779364 c.-884C>A upstream_gene_variant 0.67
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781554 c.-6C>A upstream_gene_variant 0.25
rpsL 781623 p.Ala22Thr missense_variant 0.22
rpsL 781636 p.Gly26Val missense_variant 0.25
rpsL 781806 p.Arg83Gly missense_variant 0.33
rpsL 781817 c.258G>T synonymous_variant 0.4
rpsL 781824 p.Asp89Tyr missense_variant 0.33
rplC 800671 c.-138G>T upstream_gene_variant 0.67
rplC 800768 c.-41C>T upstream_gene_variant 0.29
rplC 800803 c.-6A>G upstream_gene_variant 0.25
rplC 800823 c.15C>A synonymous_variant 0.25
rplC 800842 p.Gly12Arg missense_variant 0.33
rplC 801208 p.Gly134Cys missense_variant 0.5
rplC 801215 p.Gly136Val missense_variant 0.4
rplC 801245 p.Arg146Leu missense_variant 0.29
rplC 801301 c.493C>A synonymous_variant 0.29
rplC 801319 p.Gly171Cys missense_variant 0.22
rplC 801393 p.Lys195Asn missense_variant 0.4
fbiC 1302888 c.-43G>T upstream_gene_variant 0.5
fbiC 1303426 p.Gly166Cys missense_variant 0.67
fbiC 1304236 p.Gln436Tyr missense_variant 1.0
fbiC 1304291 p.Asp454Gly missense_variant 0.5
fbiC 1304714 p.Gly595Val missense_variant 0.5
fbiC 1304741 p.Gly604Asp missense_variant 0.5
fbiC 1304961 c.2031C>A synonymous_variant 0.29
fbiC 1304970 c.2040G>T synonymous_variant 0.5
fbiC 1304980 p.Lys684Glu missense_variant 0.33
fbiC 1305327 p.Met799Ile missense_variant 0.33
fbiC 1305416 p.Thr829Ile missense_variant 0.5
Rv1258c 1406090 c.1251G>A synonymous_variant 0.22
Rv1258c 1406099 c.1242C>A synonymous_variant 0.25
Rv1258c 1406268 p.Ala358Val missense_variant 0.33
Rv1258c 1406283 p.Thr353Met missense_variant 0.5
Rv1258c 1406440 p.Ala301Thr missense_variant 0.5
Rv1258c 1406722 p.Gly207Trp missense_variant 0.67
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
Rv1258c 1406817 p.Trp175Ser missense_variant 0.67
Rv1258c 1406855 c.486C>A synonymous_variant 0.25
Rv1258c 1406868 p.Pro158Gln missense_variant 0.29
Rv1258c 1406921 c.420C>T synonymous_variant 0.4
Rv1258c 1407214 p.Gln43* stop_gained 0.4
Rv1258c 1407217 p.Gly42Trp missense_variant 0.4
Rv1258c 1407371 c.-31C>T upstream_gene_variant 0.22
Rv1258c 1407376 c.-36C>T upstream_gene_variant 0.22
Rv1258c 1407476 c.-136G>A upstream_gene_variant 0.67
embR 1416195 p.His385Tyr missense_variant 0.4
embR 1416201 p.Gly383Trp missense_variant 0.4
embR 1416610 c.738G>A synonymous_variant 0.67
embR 1416737 p.Arg204Leu missense_variant 0.2
embR 1416739 p.Tyr203* stop_gained 0.2
embR 1416742 c.606C>A synonymous_variant 0.18
embR 1416789 p.Ala187Thr missense_variant 0.22
embR 1417387 c.-40C>A upstream_gene_variant 0.4
embR 1417442 c.-95C>A upstream_gene_variant 0.29
atpE 1460904 c.-141C>A upstream_gene_variant 0.29
atpE 1461188 c.144G>T synonymous_variant 0.33
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471930 n.88_89delGA non_coding_transcript_exon_variant 0.67
rrs 1471946 n.101C>T non_coding_transcript_exon_variant 0.29
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.43
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.29
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.57
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.57
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.57
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.44
rrs 1472128 n.283G>A non_coding_transcript_exon_variant 0.44
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.44
rrs 1472130 n.285G>A non_coding_transcript_exon_variant 0.5
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.62
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.69
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.69
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.89
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.67
rrs 1472266 n.421C>T non_coding_transcript_exon_variant 1.0
rrs 1472378 n.533G>T non_coding_transcript_exon_variant 0.64
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.64
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.64
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.31
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.4
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.22
rrs 1472498 n.653C>A non_coding_transcript_exon_variant 0.5
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.83
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.9
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.87
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.94
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.95
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.95
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.95
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.95
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.96
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.88
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.95
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.27
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.95
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.96
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.96
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.98
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.93
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.92
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.92
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.81
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.62
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.73
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.73
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.8
rrs 1472687 n.842_843insC non_coding_transcript_exon_variant 0.73
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.75
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.63
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.93
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.94
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.96
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.96
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.94
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.93
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.89
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.5
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.33
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.33
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.64
rrs 1472965 n.1120C>A non_coding_transcript_exon_variant 0.25
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.43
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.5
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.5
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.43
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.33
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.54
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.58
rrs 1473147 n.1302G>T non_coding_transcript_exon_variant 0.58
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.58
rrs 1473150 n.1305T>G non_coding_transcript_exon_variant 0.58
rrs 1473161 n.1316A>C non_coding_transcript_exon_variant 0.64
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.69
rrs 1473164 n.1319C>A non_coding_transcript_exon_variant 0.69
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.69
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.78
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.81
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.9
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.9
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.4
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.33
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.33
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.33
rrs 1473259 n.1414C>G non_coding_transcript_exon_variant 0.5
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.33
rrs 1473308 n.1463G>A non_coding_transcript_exon_variant 0.33
rrs 1473309 n.1464G>A non_coding_transcript_exon_variant 0.33
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.4
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.4
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.69
rrs 1473364 n.1519G>A non_coding_transcript_exon_variant 0.17
rrl 1473455 n.-203G>T upstream_gene_variant 0.67
rrl 1473552 n.-106G>T upstream_gene_variant 0.5
rrl 1473989 n.332C>G non_coding_transcript_exon_variant 0.67
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.27
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.25
rrl 1474234 n.577G>T non_coding_transcript_exon_variant 0.18
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.25
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.25
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.5
rrl 1474839 n.1182C>T non_coding_transcript_exon_variant 0.4
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.33
rrl 1474848 n.1191G>A non_coding_transcript_exon_variant 0.33
rrl 1474862 n.1205C>T non_coding_transcript_exon_variant 0.57
rrl 1474892 n.1235G>A non_coding_transcript_exon_variant 0.43
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.43
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.43
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.43
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.43
rrl 1474913 n.1256T>A non_coding_transcript_exon_variant 0.43
rrl 1474920 n.1263G>C non_coding_transcript_exon_variant 0.43
rrl 1475591 n.1934G>A non_coding_transcript_exon_variant 0.4
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 0.5
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.67
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.67
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.69
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.69
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.31
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.17
rrl 1476084 n.2427G>A non_coding_transcript_exon_variant 0.22
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.27
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.42
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.45
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.67
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.67
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.67
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.67
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.67
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.96
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 1.0
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 1.0
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 1.0
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 1.0
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.99
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.99
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.99
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.96
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.87
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.75
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.6
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.6
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.5
rrl 1476580 n.2923G>T non_coding_transcript_exon_variant 0.5
rrl 1476655 n.2998C>T non_coding_transcript_exon_variant 1.0
rrl 1476684 n.3027C>T non_coding_transcript_exon_variant 0.5
rrl 1476706 n.3049C>T non_coding_transcript_exon_variant 0.4
inhA 1673559 c.-643C>T upstream_gene_variant 0.5
inhA 1673709 c.-493C>A upstream_gene_variant 1.0
fabG1 1674170 p.Gly244Asp missense_variant 0.67
inhA 1674289 p.Gln30Lys missense_variant 0.67
inhA 1674470 p.Gly90Val missense_variant 0.67
inhA 1674551 p.Ser117Tyr missense_variant 0.4
inhA 1674621 c.420C>A synonymous_variant 0.67
inhA 1674738 c.537C>A synonymous_variant 0.5
inhA 1674741 c.540C>A synonymous_variant 0.5
inhA 1674817 p.Ala206Ser missense_variant 0.4
rpsA 1833522 c.-20G>A upstream_gene_variant 0.5
rpsA 1833886 c.345C>T synonymous_variant 0.4
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834210 c.669C>A synonymous_variant 0.4
rpsA 1834612 c.1071G>T synonymous_variant 0.33
rpsA 1834943 p.Ala468Ser missense_variant 0.4
rpsA 1834946 p.Gln469Glu missense_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918336 p.Arg133Trp missense_variant 0.33
tlyA 1918651 p.Glu238* stop_gained 0.4
ndh 2101673 p.Ala457Glu missense_variant 0.5
ndh 2101698 p.Ala449Ser missense_variant 0.67
ndh 2101838 p.Ala402Glu missense_variant 0.4
ndh 2101913 p.Ser377* stop_gained 0.4
ndh 2101974 p.Ala357Ser missense_variant 0.22
ndh 2101997 p.Ala349Val missense_variant 0.29
ndh 2102014 c.1029C>G synonymous_variant 0.4
ndh 2102029 p.Gln338His missense_variant 0.4
ndh 2102241 p.Arg268Ser missense_variant 0.67
ndh 2102839 c.204C>T synonymous_variant 0.29
katG 2154072 c.2040C>A synonymous_variant 1.0
katG 2154432 c.1680C>T synonymous_variant 0.5
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2154784 p.Pro443His missense_variant 0.5
katG 2154860 c.1252C>A synonymous_variant 0.5
katG 2154991 p.Ser374Tyr missense_variant 0.4
katG 2155496 p.Gly206Ser missense_variant 0.4
katG 2155701 c.411C>T synonymous_variant 0.5
katG 2156039 p.His25Tyr missense_variant 0.5
katG 2156200 c.-89G>T upstream_gene_variant 0.67
katG 2156223 c.-112G>T upstream_gene_variant 1.0
katG 2156521 c.-410C>T upstream_gene_variant 0.29
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2167985 p.Met876Ile missense_variant 0.4
PPE35 2168086 p.Glu843* stop_gained 0.33
PPE35 2168252 c.2361G>A synonymous_variant 0.22
PPE35 2168672 c.1941C>T synonymous_variant 0.33
PPE35 2168846 c.1767G>T synonymous_variant 0.29
PPE35 2169503 c.1110C>A synonymous_variant 0.25
PPE35 2170036 p.Val193Met missense_variant 0.5
PPE35 2170156 p.Ala153Ser missense_variant 0.67
PPE35 2170447 c.165delG frameshift_variant 0.67
Rv1979c 2221779 p.Met462Ile missense_variant 0.67
Rv1979c 2221801 p.Thr455Arg missense_variant 0.67
Rv1979c 2222172 c.993G>T synonymous_variant 0.5
Rv1979c 2222192 p.Arg325Trp missense_variant 0.4
Rv1979c 2222425 p.Ala247Val missense_variant 0.4
Rv1979c 2222445 c.720C>T synonymous_variant 0.5
Rv1979c 2222519 p.Gly216Cys missense_variant 0.29
Rv1979c 2222525 p.Gly214Cys missense_variant 0.29
Rv1979c 2222603 p.Gln188* stop_gained 0.29
Rv1979c 2222954 p.Tyr71His missense_variant 0.25
Rv1979c 2223077 p.Ala30Ser missense_variant 0.33
Rv1979c 2223080 p.Gly29Arg missense_variant 0.33
Rv1979c 2223088 p.Ser26Leu missense_variant 0.4
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv1979c 2223341 c.-177C>T upstream_gene_variant 0.4
pncA 2289322 c.-81C>T upstream_gene_variant 0.4
pncA 2289401 c.-160G>A upstream_gene_variant 0.4
pncA 2289410 c.-169G>A upstream_gene_variant 0.5
pncA 2289445 c.-204C>A upstream_gene_variant 0.5
pncA 2289639 c.-398C>A upstream_gene_variant 0.5
pncA 2289660 c.-419G>C upstream_gene_variant 0.67
pncA 2289992 c.-751G>T upstream_gene_variant 0.25
pncA 2290037 c.-796G>T upstream_gene_variant 0.25
pncA 2290048 c.-807C>T upstream_gene_variant 0.25
kasA 2518141 c.27C>T synonymous_variant 0.33
kasA 2518142 p.Gly10Cys missense_variant 0.33
kasA 2518225 p.Leu37Phe missense_variant 0.5
kasA 2518286 p.Val58Phe missense_variant 0.4
kasA 2518470 p.Ala119Val missense_variant 0.67
kasA 2518788 p.Arg225Gln missense_variant 0.29
kasA 2518889 p.Ala259Ser missense_variant 0.67
kasA 2518960 c.846C>T synonymous_variant 0.22
kasA 2518983 p.Ala290Glu missense_variant 0.5
kasA 2519101 c.987C>T synonymous_variant 0.5
kasA 2519249 p.Glu379Lys missense_variant 0.25
kasA 2519270 p.Ala386Pro missense_variant 0.25
eis 2714220 c.1113C>T synonymous_variant 0.4
eis 2714260 p.Ser358Ile missense_variant 0.5
eis 2714385 c.948G>A synonymous_variant 0.4
eis 2714669 p.Gly222Arg missense_variant 0.22
eis 2714674 p.Pro220His missense_variant 0.22
eis 2714771 p.Gly188Ser missense_variant 0.5
eis 2715169 p.Gly55Ala missense_variant 0.33
eis 2715187 p.Arg49His missense_variant 0.4
eis 2715216 c.117G>A synonymous_variant 0.33
eis 2715320 p.Leu5Met missense_variant 0.5
eis 2715326 p.Val3Met missense_variant 0.5
eis 2715412 c.-80C>A upstream_gene_variant 0.5
ahpC 2725934 c.-259G>A upstream_gene_variant 1.0
ahpC 2725999 c.-194C>A upstream_gene_variant 0.4
ahpC 2726057 c.-136C>T upstream_gene_variant 0.25
ahpC 2726084 c.-109C>A upstream_gene_variant 0.18
ahpC 2726139 c.-54C>A upstream_gene_variant 0.22
ahpC 2726158 c.-35C>A upstream_gene_variant 0.33
ahpC 2726384 p.Glu64Asp missense_variant 0.25
ahpC 2726774 c.582G>T synonymous_variant 0.4
ahpC 2726776 p.Ala195Val missense_variant 0.4
folC 2746227 p.Gly458Trp missense_variant 0.67
folC 2746246 c.1353C>T synonymous_variant 0.67
folC 2746370 p.Arg410Leu missense_variant 0.67
folC 2746531 c.1068G>A synonymous_variant 0.29
folC 2746555 c.1044G>A synonymous_variant 0.29
folC 2746778 p.Gly274Asp missense_variant 0.5
folC 2746827 p.Arg258Trp missense_variant 0.25
folC 2746833 p.Val256Leu missense_variant 0.25
folC 2746926 c.672delC frameshift_variant 1.0
folC 2746946 p.Gly218Val missense_variant 1.0
folC 2747026 c.573C>A synonymous_variant 0.4
folC 2747215 p.Glu128Asp missense_variant 0.29
folC 2747245 c.354G>A synonymous_variant 0.5
folC 2747252 p.Ser116Ile missense_variant 0.5
folC 2747456 p.Thr48Ile missense_variant 0.67
folC 2747493 p.Gln36Lys missense_variant 0.33
folC 2747532 p.Glu23Lys missense_variant 0.29
folC 2747569 c.30C>T synonymous_variant 0.33
folC 2747579 p.Gly7Val missense_variant 0.33
pepQ 2859617 p.Ala268Thr missense_variant 0.4
pepQ 2859644 p.Ala259Ser missense_variant 0.33
pepQ 2859657 c.762C>T synonymous_variant 0.4
pepQ 2860407 c.12C>T synonymous_variant 0.29
pepQ 2860473 c.-55C>A upstream_gene_variant 0.33
pepQ 2860487 c.-69G>A upstream_gene_variant 0.4
pepQ 2860515 c.-99_-97delCTGinsATA upstream_gene_variant 0.4
pepQ 2860519 c.-101C>A upstream_gene_variant 0.4
ribD 2986654 c.-185C>T upstream_gene_variant 0.5
Rv2752c 3064758 c.1434G>C synonymous_variant 1.0
Rv2752c 3064957 p.Ser412Asn missense_variant 0.29
Rv2752c 3065250 c.942G>A synonymous_variant 0.29
Rv2752c 3065407 p.Val262Ala missense_variant 0.33
Rv2752c 3065411 p.Phe261Leu missense_variant 0.4
Rv2752c 3065412 p.Ser260Thr missense_variant 0.4
Rv2752c 3065416 p.Val259Thr missense_variant 0.4
Rv2752c 3065421 c.771G>A synonymous_variant 0.4
Rv2752c 3065440 p.Ala251Asp missense_variant 0.33
Rv2752c 3065467 p.Val242Ala missense_variant 0.4
Rv2752c 3066110 p.Gly28Cys missense_variant 0.4
Rv2752c 3066112 c.79delA frameshift_variant 0.5
Rv2752c 3066355 c.-165delG upstream_gene_variant 0.29
Rv2752c 3067084 c.-893C>T upstream_gene_variant 0.67
Rv2752c 3067111 c.-920G>T upstream_gene_variant 0.4
thyX 3067261 p.Asp229Asn missense_variant 0.5
thyX 3067589 c.357G>A synonymous_variant 0.25
thyX 3067601 c.345G>T synonymous_variant 0.22
thyX 3067657 p.Arg97Trp missense_variant 0.33
thyA 3073867 p.Thr202Ile missense_variant 0.5
thyA 3074197 p.Pro92Leu missense_variant 0.33
thyA 3074202 c.270C>T synonymous_variant 0.29
thyA 3074554 c.-83G>T upstream_gene_variant 0.29
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086942 p.Glu41Asp missense_variant 1.0
ald 3087659 c.840G>A synonymous_variant 0.5
ald 3087746 c.927G>T synonymous_variant 0.29
ald 3087767 c.948G>T synonymous_variant 0.29
ald 3087862 p.Gly348Val missense_variant 0.33
fbiD 3339270 c.153G>T synonymous_variant 0.4
fbiD 3339360 c.243C>A synonymous_variant 0.67
fbiD 3339517 p.His134Tyr missense_variant 0.33
Rv3083 3449367 c.864G>T synonymous_variant 0.67
Rv3083 3449401 p.Val300Met missense_variant 0.22
Rv3083 3449448 c.945G>A synonymous_variant 0.29
Rv3083 3449487 c.984C>A synonymous_variant 0.4
Rv3083 3449493 c.990G>A synonymous_variant 0.4
Rv3083 3449676 c.1173C>T synonymous_variant 1.0
Rv3083 3449827 p.Gly442Ser missense_variant 1.0
fprA 3473890 c.-117C>A upstream_gene_variant 0.5
fprA 3473970 c.-37C>A upstream_gene_variant 0.5
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474719 p.Ala238Val missense_variant 0.67
fprA 3474774 c.768G>A synonymous_variant 0.33
whiB7 3568692 c.-13G>T upstream_gene_variant 1.0
whiB7 3568855 c.-176G>A upstream_gene_variant 0.67
Rv3236c 3612196 c.921C>T synonymous_variant 0.5
Rv3236c 3612427 c.690G>T synonymous_variant 0.4
Rv3236c 3612446 p.Gly224Val missense_variant 0.33
Rv3236c 3612448 c.669G>T synonymous_variant 0.29
Rv3236c 3612456 p.Arg221Trp missense_variant 0.29
Rv3236c 3612680 p.Arg146Leu missense_variant 0.22
Rv3236c 3612692 p.Arg142Leu missense_variant 0.29
Rv3236c 3612709 c.408G>T synonymous_variant 0.33
Rv3236c 3612929 p.Pro63His missense_variant 0.4
Rv3236c 3612978 p.Gly47Cys missense_variant 0.4
Rv3236c 3613024 c.93G>A synonymous_variant 0.4
Rv3236c 3613291 c.-175G>T upstream_gene_variant 0.29
fbiA 3640356 c.-187G>T upstream_gene_variant 0.29
fbiB 3640722 c.-813G>A upstream_gene_variant 0.33
fbiA 3640896 p.Met118Ile missense_variant 0.29
fbiA 3640903 p.Ala121Ser missense_variant 0.29
fbiA 3640975 p.Ala145Thr missense_variant 0.5
fbiA 3640987 p.Arg149Ser missense_variant 0.33
fbiA 3641062 p.Val174Met missense_variant 0.4
fbiA 3641236 p.Ala232Ser missense_variant 0.67
fbiB 3641917 p.Ser128Ile missense_variant 0.33
fbiB 3641960 c.426C>T synonymous_variant 0.25
fbiB 3642413 c.879G>T synonymous_variant 0.33
alr 3840494 c.927G>A synonymous_variant 0.4
alr 3840534 p.Gly296Glu missense_variant 0.33
alr 3840551 c.870G>T synonymous_variant 0.5
alr 3840625 p.Leu266Ile missense_variant 0.67
alr 3840885 c.534_535delGT frameshift_variant 0.5
alr 3841036 p.Gln129* stop_gained 0.33
alr 3841324 p.Gly33Ser missense_variant 0.4
alr 3841368 p.Arg18Leu missense_variant 0.25
alr 3841370 p.Gly17Val missense_variant 0.25
rpoA 3877794 c.714G>T synonymous_variant 0.67
rpoA 3878367 c.141C>A synonymous_variant 0.4
ddn 3986673 c.-171C>T upstream_gene_variant 1.0
clpC1 4038563 c.2142C>T synonymous_variant 1.0
clpC1 4038655 p.Gly684Cys missense_variant 0.29
clpC1 4038678 p.Pro676Gln missense_variant 0.29
clpC1 4038991 p.Gly572Ser missense_variant 0.33
clpC1 4039155 p.Arg517Gln missense_variant 0.4
clpC1 4039165 p.Leu514Met missense_variant 0.33
clpC1 4039346 c.1359G>T synonymous_variant 0.5
clpC1 4039564 p.Ala381Ser missense_variant 1.0
clpC1 4039803 p.Ala301Val missense_variant 0.5
clpC1 4039844 c.861C>T synonymous_variant 0.33
clpC1 4039934 c.771G>A synonymous_variant 0.33
clpC1 4040296 p.Gln137* stop_gained 0.67
clpC1 4040660 c.45G>T synonymous_variant 0.5
embC 4239942 p.Arg27Leu missense_variant 0.5
embC 4240044 p.Trp61Leu missense_variant 0.4
embC 4240048 c.186C>A synonymous_variant 0.4
embC 4240089 p.Gly76Val missense_variant 0.5
embC 4240319 p.Gln153* stop_gained 0.22
embC 4241028 p.Trp389* stop_gained 0.4
embC 4241074 c.1212G>T synonymous_variant 0.22
embC 4241102 p.Glu414* stop_gained 0.25
embC 4241105 p.Arg415Trp missense_variant 0.25
embC 4241416 c.1554C>A synonymous_variant 0.67
embC 4241553 p.Pro564Gln missense_variant 0.4
embC 4241641 c.1779C>T synonymous_variant 0.4
embC 4241644 c.1782G>T synonymous_variant 0.4
embC 4241703 p.Arg614Leu missense_variant 0.4
embC 4241925 p.Arg688Leu missense_variant 0.67
embC 4241928 p.Arg689Leu missense_variant 0.67
embC 4242255 p.Pro798Gln missense_variant 1.0
embA 4243141 c.-92C>T upstream_gene_variant 0.33
embA 4243201 c.-32G>T upstream_gene_variant 0.5
embA 4243273 p.Arg14His missense_variant 0.33
embA 4243287 p.Val19Ile missense_variant 0.33
embA 4243522 p.Gly97Val missense_variant 1.0
embA 4244093 c.861C>A synonymous_variant 0.67
embA 4244269 p.Arg346Leu missense_variant 0.4
embA 4244304 c.1072C>A synonymous_variant 1.0
embA 4244721 p.Gln497* stop_gained 0.67
embA 4244798 c.1566G>T synonymous_variant 0.5
embA 4245437 p.Met735Ile missense_variant 0.33
embA 4245460 p.Pro743Leu missense_variant 0.25
embA 4245663 p.Gly811Cys missense_variant 0.67
embA 4246271 p.Gln1013His missense_variant 0.67
embA 4246294 p.Trp1021Ser missense_variant 0.4
embB 4246618 c.105G>T synonymous_variant 1.0
embB 4246692 p.Gln60Arg missense_variant 0.67
embB 4246877 p.Arg122Cys missense_variant 0.4
embB 4247186 p.Ala225Leu missense_variant 0.67
embB 4247442 p.Ala310Asp missense_variant 0.33
embB 4247854 c.1341C>T synonymous_variant 0.4
embB 4248171 p.Ala553Val missense_variant 0.33
embB 4248382 c.1869C>A synonymous_variant 0.67
embB 4248506 p.Gly665Arg missense_variant 0.29
embB 4248553 c.2040C>T synonymous_variant 0.67
embB 4248846 p.Gly778Val missense_variant 0.67
embB 4249121 p.Asp870His missense_variant 0.2
embB 4249144 c.2631G>A synonymous_variant 0.2
embB 4249147 c.2634C>T synonymous_variant 0.22
embB 4249152 p.Ala880Val missense_variant 0.22
embB 4249154 p.Gly881Cys missense_variant 0.22
embB 4249196 p.Gly895Arg missense_variant 0.29
embB 4249220 p.Ala903Ser missense_variant 0.4
embB 4249471 c.2958G>A synonymous_variant 0.29
embB 4249785 p.Pro1091Leu missense_variant 0.22
aftB 4266996 p.Gly614Val missense_variant 0.25
aftB 4267560 p.Ala426Val missense_variant 0.5
aftB 4267647 p.Asp397Gly missense_variant 1.0
aftB 4267695 p.Gly381Glu missense_variant 0.29
aftB 4268357 p.Gln160His missense_variant 0.4
aftB 4268747 c.90C>T synonymous_variant 0.4
aftB 4269366 c.-530G>A upstream_gene_variant 0.5
aftB 4269681 c.-845G>T upstream_gene_variant 0.4
ubiA 4269713 p.Gly41Cys missense_variant 0.33
ubiA 4269787 p.Gly16Val missense_variant 0.33
aftB 4269804 c.-968G>T upstream_gene_variant 0.4
aftB 4269819 c.-983G>T upstream_gene_variant 0.4
ethA 4326285 p.Leu397Met missense_variant 0.4
ethA 4326472 c.1002G>T synonymous_variant 0.25
ethA 4326538 c.936G>T synonymous_variant 0.2
ethA 4327028 p.Pro149Arg missense_variant 0.5
ethR 4328014 p.Glu156* stop_gained 0.33
ethR 4328044 p.Leu166Met missense_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407620 p.Tyr195His missense_variant 1.0
gid 4407747 c.456G>A synonymous_variant 0.33
gid 4407927 p.Glu92Asp missense_variant 1.0
gid 4408439 c.-237G>A upstream_gene_variant 0.33