TB-Profiler result

Run: SRR5818402
Summary

Run ID: SRR5818402

Sample name:

Date: 04-04-2023 11:21:12

Number of reads: 315368

Percentage reads mapped: 98.54

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.4 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
mmpR5 779434 p.Val149Ile missense_variant 0.99
rrs 1472119 n.274G>A non_coding_transcript_exon_variant 0.18
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.95
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.93
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.89
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.37
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.53
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.36
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.52
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.53
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.14
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.52
rrs 1472436 n.591G>T non_coding_transcript_exon_variant 0.52
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.55
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.54
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.55
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 0.55
rrs 1472450 n.605A>C non_coding_transcript_exon_variant 0.56
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 0.55
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.57
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.57
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.57
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.57
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.57
rrs 1472486 n.641A>G non_coding_transcript_exon_variant 0.26
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.45
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.72
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.51
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.62
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.74
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.43
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.28
rrs 1472571 n.726G>T non_coding_transcript_exon_variant 0.3
rrs 1472579 n.734G>A non_coding_transcript_exon_variant 0.23
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.87
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.74
rrs 1472582 n.737G>T non_coding_transcript_exon_variant 0.2
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.63
rrs 1472585 n.740A>C non_coding_transcript_exon_variant 0.18
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.49
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.39
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.35
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.79
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.78
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.25
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.75
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.28
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.75
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.22
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.16
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.12
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.16
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.22
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.14
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.31
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.27
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.24
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.33
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.36
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.18
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.18
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.14
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.34
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.37
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.46
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.13
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.22
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.35
rrl 1476253 n.2596A>G non_coding_transcript_exon_variant 0.15
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.33
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.38
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.27
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.12
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.17
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.14
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.19
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.14
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.15
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.19
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.22
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.17
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.13
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.14
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.15
rrl 1476544 n.2887T>C non_coding_transcript_exon_variant 0.24
tlyA 1917972 c.33A>G synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 0.98
gid 4407588 c.615A>G synonymous_variant 0.98
gid 4407873 c.330G>T synonymous_variant 0.99