TB-Profiler result

Run: SRR5818436
Summary

Run ID: SRR5818436

Sample name:

Date: 04-04-2023 11:27:58

Number of reads: 27366

Percentage reads mapped: 96.41

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.87
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.72
rrs 1472207 n.362A>G non_coding_transcript_exon_variant 0.17
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.8
rrs 1472282 n.437T>G non_coding_transcript_exon_variant 0.57
rrs 1472284 n.439C>T non_coding_transcript_exon_variant 0.56
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.57
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.59
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.63
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.59
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.71
rrs 1472332 n.487A>G non_coding_transcript_exon_variant 0.74
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.73
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.78
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.78
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.78
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.65
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.4
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.33
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.25
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.19
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.24
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.23
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.19
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.4
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.24
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.49
rrs 1472505 n.660G>A non_coding_transcript_exon_variant 0.17
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.18
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.23
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.19
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.2
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.2
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.36
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.39
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.38
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.24
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.17
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.18
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.29
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.26
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.26
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.31
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.32
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.22
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.21
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.21
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.21
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.21
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.19
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.18
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.18
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.16
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.22
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.24
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.21
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.23
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.21
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.15
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.16
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.23
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.24
rrl 1476548 n.2891T>C non_coding_transcript_exon_variant 0.3
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.47
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.54
rrl 1476600 n.2943A>C non_coding_transcript_exon_variant 0.47
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.36
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.29
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.33
tlyA 1917972 c.33A>G synonymous_variant 1.0
ahpC 2726184 c.-9A>C upstream_gene_variant 0.47
ahpC 2726338 p.Val49Gly missense_variant 0.22
ahpC 2726341 p.Val50Gly missense_variant 0.27