TB-Profiler result

Run: SRR8692893
Summary

Run ID: SRR8692893

Sample name:

Date: 13-08-2023 19:59:47

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.99
lineage4.9 Euro-American (H37Rv-like) T1 None 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rplC 801268 p.Cys154Arg missense_variant 0.71 linezolid
pncA 2289081 p.Pro54Gln missense_variant 0.14 pyrazinamide
pncA 2289105 p.Ala46Glu missense_variant 0.14 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6799 c.-503C>A upstream_gene_variant 0.15
gyrA 6826 c.-476G>T upstream_gene_variant 0.15
gyrA 7362 p.Glu21Gln missense_variant 0.33
gyrA 7524 c.223C>A synonymous_variant 0.25
gyrA 7541 c.240C>A synonymous_variant 0.29
gyrA 7585 p.Ser95Thr missense_variant 0.29
gyrA 7592 c.291G>C synonymous_variant 0.25
gyrA 7595 c.294C>G synonymous_variant 0.25
gyrA 7607 c.306C>G synonymous_variant 0.25
gyrA 7631 c.330G>C synonymous_variant 0.3
gyrA 7637 c.336C>T synonymous_variant 0.33
gyrA 7658 c.357A>G synonymous_variant 0.33
gyrA 7661 c.360C>T synonymous_variant 0.33
gyrA 7664 c.363T>C synonymous_variant 0.33
gyrA 7670 c.369A>G synonymous_variant 0.33
gyrA 7676 c.375G>C synonymous_variant 0.33
gyrA 7679 c.378G>C synonymous_variant 0.33
gyrA 7683 c.382_384delAGGinsCGC synonymous_variant 0.3
gyrA 7694 c.393A>G synonymous_variant 0.27
gyrA 7700 c.399G>T synonymous_variant 0.25
gyrA 7706 c.405C>T synonymous_variant 0.17
gyrA 7709 c.408G>A synonymous_variant 0.17
gyrA 7710 c.409T>C synonymous_variant 0.17
gyrA 7715 c.414G>C synonymous_variant 0.17
gyrA 7728 c.427_429delAGGinsCGT synonymous_variant 0.15
gyrA 8016 p.Gly239Cys missense_variant 0.15
gyrA 9143 c.1842T>C synonymous_variant 0.18
gyrA 9218 c.1917C>T synonymous_variant 0.29
gyrA 9230 c.1929T>C synonymous_variant 0.29
gyrA 9236 c.1935G>C synonymous_variant 0.29
gyrA 9242 c.1941A>C synonymous_variant 0.25
gyrA 9248 c.1947G>C synonymous_variant 0.22
gyrA 9252 p.Val651Ile missense_variant 0.2
gyrA 9266 p.Asp655Glu missense_variant 0.22
gyrA 9267 p.Asn656Gly missense_variant 0.25
gyrA 9275 c.1974G>A synonymous_variant 0.22
gyrA 9296 c.1995T>C synonymous_variant 0.2
gyrA 9299 c.1998G>C synonymous_variant 0.22
gyrA 9304 p.Gly668Glu missense_variant 0.22
gyrA 9311 c.2010C>T synonymous_variant 0.22
gyrA 9324 c.2023_2025delTCGinsAGC synonymous_variant 0.2
gyrA 9335 c.2034G>T synonymous_variant 0.17
gyrA 9345 c.2044A>C synonymous_variant 0.17
gyrA 9783 p.Val828Met missense_variant 0.22
fgd1 491019 p.Phe79Leu missense_variant 0.18
fgd1 491742 c.960T>C synonymous_variant 0.27
mshA 575166 c.-182G>T upstream_gene_variant 0.2
mshA 575240 c.-108G>T upstream_gene_variant 0.2
mshA 576476 p.Leu377Met missense_variant 0.17
mshA 576508 c.1161C>A synonymous_variant 0.14
rpoB 760172 c.366G>C synonymous_variant 0.14
rpoB 760181 c.375T>G synonymous_variant 0.15
rpoB 760184 c.378A>G synonymous_variant 0.15
rpoB 760234 p.Ser143Ile missense_variant 0.14
rpoB 760244 c.438G>C synonymous_variant 0.14
rpoB 760256 c.450C>T synonymous_variant 0.18
rpoB 760283 c.477G>C synonymous_variant 0.17
rpoB 760298 c.492G>C synonymous_variant 0.17
rpoB 760502 c.696C>G synonymous_variant 0.12
rpoB 760508 c.702G>C synonymous_variant 0.13
rpoB 760511 c.705G>C synonymous_variant 0.19
rpoB 760522 p.Ser239Asn missense_variant 0.19
rpoB 760532 c.726T>C synonymous_variant 0.27
rpoB 760535 c.729C>G synonymous_variant 0.29
rpoB 760541 c.735G>C synonymous_variant 0.27
rpoB 760547 c.741G>C synonymous_variant 0.25
rpoB 760561 c.757_758delCG frameshift_variant 0.25
rpoB 760567 p.Ser254Trp missense_variant 0.27
rpoB 760568 c.762_763insGC frameshift_variant 0.27
rpoB 760591 p.Val262Ala missense_variant 0.33
rpoB 760601 c.795C>T synonymous_variant 0.2
rpoB 760611 c.805T>C synonymous_variant 0.22
rpoB 761051 c.1245G>T synonymous_variant 0.15
rpoB 761054 c.1248G>C synonymous_variant 0.17
rpoB 761057 c.1251G>C synonymous_variant 0.17
rpoB 761060 c.1254C>G synonymous_variant 0.17
rpoB 761063 c.1257C>G synonymous_variant 0.17
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.2
rpoB 761102 c.1296A>G synonymous_variant 0.17
rpoB 761132 c.1326G>T synonymous_variant 0.22
rpoB 761133 c.1327T>C synonymous_variant 0.24
rpoB 761147 c.1341C>T synonymous_variant 0.19
rpoB 761150 c.1344A>T synonymous_variant 0.19
rpoB 761165 c.1359G>C synonymous_variant 0.2
rpoB 761180 c.1374A>C synonymous_variant 0.21
rpoB 761189 c.1383T>C synonymous_variant 0.15
rpoB 761195 c.1389G>C synonymous_variant 0.15
rpoB 761198 c.1392G>T synonymous_variant 0.2
rpoB 761217 p.Pro471Ser missense_variant 0.19
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.17
rpoB 761249 c.1443A>G synonymous_variant 0.17
rpoB 761261 c.1455G>C synonymous_variant 0.17
rpoB 761264 c.1458C>G synonymous_variant 0.17
rpoB 761655 p.Ala617Ser missense_variant 0.18
rpoB 761990 c.2184G>C synonymous_variant 0.2
rpoB 761999 c.2193G>C synonymous_variant 0.2
rpoB 762002 c.2196C>G synonymous_variant 0.22
rpoB 762053 c.2247T>C synonymous_variant 0.12
rpoB 762065 c.2259T>C synonymous_variant 0.12
rpoC 762596 c.-774G>T upstream_gene_variant 0.5
rpoB 762879 p.Met1025Leu missense_variant 0.15
rpoC 762899 c.-471G>C upstream_gene_variant 0.12
rpoC 762917 c.-453C>G upstream_gene_variant 0.15
rpoC 762920 c.-450C>T upstream_gene_variant 0.17
rpoC 762923 c.-447C>G upstream_gene_variant 0.17
rpoC 762929 c.-441G>C upstream_gene_variant 0.2
rpoC 762959 c.-411G>C upstream_gene_variant 0.18
rpoC 762962 c.-408C>T upstream_gene_variant 0.18
rpoC 762983 c.-387C>T upstream_gene_variant 0.31
rpoC 762989 c.-381G>A upstream_gene_variant 0.31
rpoC 762995 c.-375G>T upstream_gene_variant 0.29
rpoC 763004 c.-366G>A upstream_gene_variant 0.21
rpoC 763007 c.-363C>T upstream_gene_variant 0.21
rpoC 763031 c.-339T>C upstream_gene_variant 0.12
rpoC 763115 c.-255T>C upstream_gene_variant 0.14
rpoC 763414 c.45T>G synonymous_variant 0.12
rpoC 763423 p.Glu18Asp missense_variant 0.12
rpoC 763430 c.61_63delAGGinsCGC synonymous_variant 0.15
rpoC 763433 p.Gln22Asn missense_variant 0.15
rpoC 763443 p.Tyr25Phe missense_variant 0.14
rpoC 763456 c.87A>G synonymous_variant 0.2
rpoC 763468 c.99G>C synonymous_variant 0.17
rpoC 763486 c.117T>C synonymous_variant 0.17
rpoC 763495 c.126G>A synonymous_variant 0.15
rpoC 763546 c.177A>G synonymous_variant 0.13
rpoC 764044 c.675T>C synonymous_variant 0.12
rpoC 764071 c.702G>C synonymous_variant 0.12
rpoC 764077 c.708C>G synonymous_variant 0.13
rpoC 764083 c.714A>G synonymous_variant 0.14
rpoC 764084 p.Asn239Val missense_variant 0.15
rpoC 764098 c.729A>G synonymous_variant 0.17
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.4
rpoC 764410 c.1041G>C synonymous_variant 0.5
rpoC 764452 c.1083T>C synonymous_variant 0.2
rpoC 764458 c.1089G>C synonymous_variant 0.22
rpoC 764461 c.1092A>G synonymous_variant 0.2
rpoC 764485 c.1116G>C synonymous_variant 0.18
rpoC 764491 c.1122G>T synonymous_variant 0.2
rpoC 764497 c.1128A>G synonymous_variant 0.18
rpoC 764500 c.1131C>G synonymous_variant 0.18
rpoC 764521 c.1152T>C synonymous_variant 0.17
rpoC 764527 c.1158C>T synonymous_variant 0.17
rpoC 764530 c.1161C>T synonymous_variant 0.17
rpoC 764539 c.1170C>G synonymous_variant 0.18
rpoC 764602 c.1233C>A synonymous_variant 0.17
rpoC 764662 c.1293G>C synonymous_variant 0.15
rpoC 764677 c.1308C>G synonymous_variant 0.15
rpoC 764719 c.1350G>A synonymous_variant 0.25
rpoC 764746 c.1377G>T synonymous_variant 0.3
rpoC 764752 c.1383G>C synonymous_variant 0.33
rpoC 764758 c.1389C>G synonymous_variant 0.33
rpoC 764764 c.1395T>C synonymous_variant 0.33
rpoC 764800 c.1431G>A synonymous_variant 0.6
rpoC 764803 c.1434C>T synonymous_variant 0.5
rpoC 764809 c.1440C>T synonymous_variant 0.5
rpoC 764815 c.1446A>G synonymous_variant 0.4
rpoC 764827 c.1458G>C synonymous_variant 0.33
rpoC 765808 p.Gln813His missense_variant 0.33
rpoC 766171 c.2802C>A synonymous_variant 0.18
rpoC 766632 p.Val1088Ala missense_variant 0.12
rpoC 767155 c.3786C>G synonymous_variant 0.18
rpoC 767162 p.Asn1265Ala missense_variant 0.17
rpoC 767173 c.3804C>G synonymous_variant 0.17
rpoC 767174 p.Asn1269Asp missense_variant 0.17
rpoC 767180 p.Ala1271Gln missense_variant 0.17
rpoC 767185 c.3816G>C synonymous_variant 0.17
rpoC 767186 p.Gln1273Asn missense_variant 0.17
rpoC 767191 c.3822C>G synonymous_variant 0.17
rpoC 767197 c.3828G>A synonymous_variant 0.18
rpoC 767221 c.3852C>G synonymous_variant 0.17
mmpL5 775758 p.Thr908Asn missense_variant 0.22
mmpL5 775768 p.Gln905Lys missense_variant 0.27
mmpL5 777121 p.His454Asn missense_variant 0.14
mmpL5 777232 p.Asp417Tyr missense_variant 0.22
mmpL5 778227 p.Gly85Glu missense_variant 0.13
mmpS5 778537 p.Lys123Asn missense_variant 0.14
mmpR5 779215 p.Gln76Lys missense_variant 0.14
mmpR5 779359 p.Ala124Thr missense_variant 0.18
mmpR5 779449 p.Leu154Met missense_variant 0.13
rplC 800612 c.-197A>G upstream_gene_variant 0.17
rplC 800618 c.-191T>C upstream_gene_variant 0.14
rplC 800628 c.-181G>C upstream_gene_variant 0.15
rplC 800633 c.-176T>C upstream_gene_variant 0.17
rplC 800639 c.-170C>T upstream_gene_variant 0.15
rplC 800759 c.-50C>A upstream_gene_variant 0.25
fbiC 1302956 p.Ser9Tyr missense_variant 0.17
fbiC 1303097 p.Ala56Asp missense_variant 0.22
fbiC 1303367 p.Thr146Asn missense_variant 0.18
fbiC 1303503 c.573G>C synonymous_variant 0.17
fbiC 1303509 c.579G>C synonymous_variant 0.17
fbiC 1303512 c.582T>G synonymous_variant 0.17
fbiC 1303525 p.Ser199Thr missense_variant 0.18
fbiC 1303531 p.Met201Leu missense_variant 0.17
fbiC 1303536 c.606G>C synonymous_variant 0.14
fbiC 1303542 c.612C>G synonymous_variant 0.13
fbiC 1303548 c.618G>C synonymous_variant 0.13
fbiC 1303806 c.876G>T synonymous_variant 0.25
fbiC 1303992 p.Trp354Cys missense_variant 0.2
fbiC 1304746 p.Asp606Tyr missense_variant 0.17
fbiC 1305310 p.Arg794Trp missense_variant 0.25
Rv1258c 1406113 p.Asp410Tyr missense_variant 0.22
Rv1258c 1406686 p.Val219Ile missense_variant 1.0
embR 1416382 p.Ser322Arg missense_variant 0.29
embR 1416535 c.813C>T synonymous_variant 0.14
embR 1416668 p.Ala227Val missense_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.17
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.18
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.25
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.22
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.27
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.27
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.27
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.27
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.25
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.25
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.31
rrs 1472043 n.198T>G non_coding_transcript_exon_variant 0.31
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.33
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.29
rrs 1472102 n.257G>T non_coding_transcript_exon_variant 0.15
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.31
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.31
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.29
rrs 1472204 n.359G>T non_coding_transcript_exon_variant 0.15
rrs 1472206 n.361G>T non_coding_transcript_exon_variant 0.17
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.27
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.3
rrs 1472289 n.444T>C non_coding_transcript_exon_variant 0.3
rrs 1472290 n.445C>A non_coding_transcript_exon_variant 0.33
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.38
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.3
rrs 1472324 n.479G>T non_coding_transcript_exon_variant 0.33
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.33
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.33
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.44
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.4
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.54
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.5
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.54
rrs 1472502 n.657G>T non_coding_transcript_exon_variant 0.17
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.4
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.18
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.18
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.18
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.18
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.17
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.17
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.17
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.18
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.22
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.22
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.2
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.2
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.2
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.22
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.22
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.25
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.25
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.56
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.45
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.5
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.46
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.38
rrl 1473515 n.-143G>T upstream_gene_variant 0.25
rrl 1473554 n.-104G>T upstream_gene_variant 0.2
rrl 1473633 n.-25C>A upstream_gene_variant 0.22
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.23
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.2
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.2
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 0.25
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.25
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.31
rrl 1473757 n.100T>C non_coding_transcript_exon_variant 0.12
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.31
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.33
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.44
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.29
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.29
rrl 1473816 n.159C>G non_coding_transcript_exon_variant 0.29
rrl 1473828 n.171G>C non_coding_transcript_exon_variant 0.4
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.4
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.4
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.4
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.33
rrl 1474011 n.354G>A non_coding_transcript_exon_variant 0.25
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.29
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.29
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.25
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.33
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.33
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.33
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.38
rrl 1474232 n.575C>A non_coding_transcript_exon_variant 0.2
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.54
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.44
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.44
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.3
rrl 1474473 n.816C>A non_coding_transcript_exon_variant 0.29
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.5
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.18
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.25
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.25
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.27
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.27
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.27
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.38
rrl 1474810 n.1153G>T non_coding_transcript_exon_variant 0.17
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.33
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.31
rrl 1474888 n.1231C>A non_coding_transcript_exon_variant 0.22
rrl 1474946 n.1289C>A non_coding_transcript_exon_variant 0.2
rrl 1475108 n.1451C>G non_coding_transcript_exon_variant 0.67
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.4
rrl 1475358 n.1701T>C non_coding_transcript_exon_variant 0.4
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.4
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.33
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.33
rrl 1475381 n.1724G>T non_coding_transcript_exon_variant 0.33
rrl 1475382 n.1725A>C non_coding_transcript_exon_variant 0.33
rrl 1475395 n.1738T>G non_coding_transcript_exon_variant 0.33
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 0.33
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.33
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.38
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.7
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.7
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.75
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.73
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.62
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.62
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.62
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.62
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.62
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.57
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.69
rrl 1475759 n.2102C>T non_coding_transcript_exon_variant 0.67
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.67
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.67
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.67
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.67
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.67
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.54
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.64
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.69
rrl 1476018 n.2361G>T non_coding_transcript_exon_variant 0.14
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.67
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.67
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.67
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.67
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.67
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.67
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.67
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.67
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.69
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.71
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.64
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.67
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.67
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.67
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.67
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.67
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.67
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.25
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.25
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.25
rrl 1476259 n.2602C>A non_coding_transcript_exon_variant 0.5
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.33
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.5
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.57
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.57
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.31
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.44
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.47
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.47
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.54
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.42
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.38
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.2
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.2
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.2
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.2
fabG1 1673324 c.-116G>T upstream_gene_variant 0.21
inhA 1674228 c.27G>T synonymous_variant 0.2
inhA 1674376 p.Pro59Thr missense_variant 0.17
inhA 1674659 p.Arg153Leu missense_variant 0.13
inhA 1674835 p.Gly212Arg missense_variant 0.18
rpsA 1833595 c.54T>G synonymous_variant 0.14
rpsA 1833596 p.Ser19Ala missense_variant 0.14
rpsA 1833616 c.75A>G synonymous_variant 0.14
rpsA 1833619 c.78A>C synonymous_variant 0.14
rpsA 1833625 c.84A>G synonymous_variant 0.13
rpsA 1833628 c.87G>C synonymous_variant 0.13
rpsA 1833676 c.135A>G synonymous_variant 0.19
rpsA 1833679 c.138G>C synonymous_variant 0.19
rpsA 1833685 c.144G>T synonymous_variant 0.19
rpsA 1833694 c.153G>T synonymous_variant 0.19
rpsA 1833697 c.156C>G synonymous_variant 0.18
rpsA 1833703 c.162C>T synonymous_variant 0.19
rpsA 1833709 c.168C>T synonymous_variant 0.17
rpsA 1833745 c.204G>C synonymous_variant 0.14
rpsA 1833787 c.246C>G synonymous_variant 0.17
rpsA 1833790 c.249T>C synonymous_variant 0.17
rpsA 1833793 c.252C>T synonymous_variant 0.17
rpsA 1833802 c.261A>G synonymous_variant 0.19
rpsA 1833808 c.267G>C synonymous_variant 0.19
rpsA 1833811 c.270G>T synonymous_variant 0.17
rpsA 1833829 c.288A>G synonymous_variant 0.2
rpsA 1833832 c.291G>A synonymous_variant 0.2
rpsA 1833838 c.297G>C synonymous_variant 0.19
rpsA 1833841 c.300C>G synonymous_variant 0.19
rpsA 1833847 c.306C>G synonymous_variant 0.18
rpsA 1833856 c.315A>G synonymous_variant 0.18
rpsA 1833862 c.321G>T synonymous_variant 0.17
rpsA 1833892 c.351G>A synonymous_variant 0.17
rpsA 1833894 p.Ala118Glu missense_variant 0.17
rpsA 1833928 c.387G>C synonymous_variant 0.2
rpsA 1833970 c.429G>C synonymous_variant 0.18
rpsA 1833976 c.435C>T synonymous_variant 0.18
rpsA 1833979 c.438T>C synonymous_variant 0.18
rpsA 1834177 c.636A>C synonymous_variant 0.2
rpsA 1834213 c.672G>C synonymous_variant 0.15
rpsA 1834216 p.Phe225Leu missense_variant 0.15
rpsA 1834231 c.690T>C synonymous_variant 0.14
rpsA 1834234 c.693G>C synonymous_variant 0.14
rpsA 1834240 c.699T>C synonymous_variant 0.23
rpsA 1834249 c.708T>C synonymous_variant 0.23
rpsA 1834261 c.720A>G synonymous_variant 0.25
rpsA 1834264 c.723G>C synonymous_variant 0.25
rpsA 1834279 c.738C>T synonymous_variant 0.22
rpsA 1834294 c.753G>C synonymous_variant 0.21
rpsA 1834298 p.Gln253Thr missense_variant 0.21
rpsA 1834303 c.762T>C synonymous_variant 0.22
rpsA 1834306 c.765T>C synonymous_variant 0.22
rpsA 1834348 c.807T>C synonymous_variant 0.2
rpsA 1834361 c.820T>C synonymous_variant 0.19
rpsA 1834366 c.825A>G synonymous_variant 0.19
rpsA 1834387 c.846C>T synonymous_variant 0.26
rpsA 1834396 c.855G>C synonymous_variant 0.22
rpsA 1834411 c.870T>C synonymous_variant 0.19
rpsA 1834417 c.876G>C synonymous_variant 0.2
rpsA 1834423 c.882G>C synonymous_variant 0.22
rpsA 1834451 c.910T>C synonymous_variant 0.19
rpsA 1834456 c.915T>G synonymous_variant 0.19
rpsA 1834468 c.927A>G synonymous_variant 0.19
rpsA 1834489 c.948T>C synonymous_variant 0.17
rpsA 1834513 c.972C>G synonymous_variant 0.26
rpsA 1834520 p.Ala327Ser missense_variant 0.23
rpsA 1834528 c.987T>C synonymous_variant 0.21
rpsA 1834540 c.999G>C synonymous_variant 0.21
rpsA 1834543 c.1002C>G synonymous_variant 0.21
rpsA 1834546 c.1005T>C synonymous_variant 0.21
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.21
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.22
rpsA 1834606 c.1065C>T synonymous_variant 0.26
rpsA 1834609 c.1068T>C synonymous_variant 0.26
rpsA 1834619 c.1078T>C synonymous_variant 0.25
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.25
rpsA 1834633 c.1092A>G synonymous_variant 0.28
rpsA 1834639 c.1098T>C synonymous_variant 0.28
rpsA 1834666 c.1125G>C synonymous_variant 0.18
rpsA 1834667 p.Ala376Ser missense_variant 0.18
rpsA 1834690 c.1149T>C synonymous_variant 0.2
rpsA 1834700 p.Gln387Ala missense_variant 0.22
rpsA 1834705 c.1164C>G synonymous_variant 0.22
rpsA 1834732 c.1191T>C synonymous_variant 0.2
tlyA 1918247 p.Arg103His missense_variant 0.18
ndh 2102575 p.Glu156Asp missense_variant 0.2
katG 2153975 p.Ala713Ser missense_variant 0.2
katG 2154439 p.Ala558Glu missense_variant 0.29
katG 2155452 c.660G>T synonymous_variant 0.22
katG 2155471 p.Arg214Leu missense_variant 0.2
katG 2155626 c.486G>A synonymous_variant 0.33
katG 2155800 c.312G>A synonymous_variant 0.14
katG 2156334 c.-223G>T upstream_gene_variant 0.38
katG 2156560 c.-449C>A upstream_gene_variant 0.19
PPE35 2168178 p.Pro812Leu missense_variant 0.29
PPE35 2170046 c.567C>A synonymous_variant 0.5
PPE35 2170568 p.Ile15Met missense_variant 0.33
Rv1979c 2222560 p.Ala202Glu missense_variant 0.22
Rv1979c 2223022 p.Pro48Gln missense_variant 0.22
Rv1979c 2223031 p.Pro45His missense_variant 0.25
Rv1979c 2223059 p.Pro36Thr missense_variant 0.25
Rv1979c 2223250 c.-86C>A upstream_gene_variant 0.14
Rv1979c 2223262 c.-98C>A upstream_gene_variant 0.14
Rv1979c 2223275 c.-111C>A upstream_gene_variant 0.13
kasA 2517941 c.-174C>G upstream_gene_variant 0.16
kasA 2518315 c.201G>T synonymous_variant 0.17
kasA 2518527 p.Ser138Tyr missense_variant 0.14
kasA 2518946 p.Val278Leu missense_variant 0.29
eis 2714337 p.Lys332Asn missense_variant 0.14
eis 2714871 c.462G>T synonymous_variant 0.2
ahpC 2726323 p.Pro44Gln missense_variant 0.13
folC 2746692 p.Val303Leu missense_variant 0.18
folC 2746794 p.Gln269Lys missense_variant 0.5
folC 2746918 c.681G>T synonymous_variant 0.2
pepQ 2859548 p.Gly291Cys missense_variant 0.2
pepQ 2859557 p.Glu288* stop_gained 0.2
pepQ 2859940 p.Arg160Leu missense_variant 0.14
pepQ 2860422 c.-4G>T upstream_gene_variant 0.17
ribD 2987533 p.Gly232Val missense_variant 0.25
Rv2752c 3064895 p.Ala433Thr missense_variant 0.18
Rv2752c 3065931 c.261C>T synonymous_variant 0.29
thyA 3074037 c.435C>A synonymous_variant 0.18
ald 3087767 c.948G>T synonymous_variant 0.2
fbiD 3339332 p.Ala72Glu missense_variant 0.13
Rv3083 3448358 c.-146G>T upstream_gene_variant 0.15
Rv3083 3449030 p.Ser176Tyr missense_variant 0.4
Rv3083 3449063 p.Ala187Glu missense_variant 0.18
Rv3083 3449507 p.Arg335Leu missense_variant 0.14
Rv3083 3449682 c.1179G>A synonymous_variant 0.2
fprA 3475046 p.Arg347Leu missense_variant 0.15
Rv3236c 3611991 p.Gly376Trp missense_variant 0.14
Rv3236c 3612577 p.Glu180Asp missense_variant 0.17
Rv3236c 3612871 p.Phe82Leu missense_variant 0.18
fbiB 3641939 c.405G>T synonymous_variant 0.4
fbiB 3642030 p.Gly166Cys missense_variant 0.25
fbiB 3642164 c.630C>A synonymous_variant 0.33
fbiB 3642627 p.Arg365Ser missense_variant 0.17
alr 3840333 p.Ala363Glu missense_variant 0.15
alr 3841180 p.Ala81Thr missense_variant 0.22
alr 3841458 c.-38G>T upstream_gene_variant 0.14
ddn 3986794 c.-50G>T upstream_gene_variant 0.33
ddn 3987192 p.Glu117* stop_gained 0.25
clpC1 4038318 p.Pro796Gln missense_variant 0.15
clpC1 4038647 c.2058T>C synonymous_variant 0.15
clpC1 4038650 c.2055C>T synonymous_variant 0.15
clpC1 4039064 c.1641C>T synonymous_variant 0.18
clpC1 4039067 c.1638G>C synonymous_variant 0.18
clpC1 4039079 c.1626C>G synonymous_variant 0.18
clpC1 4039085 c.1620A>G synonymous_variant 0.2
clpC1 4039091 c.1614G>C synonymous_variant 0.2
clpC1 4039097 c.1608G>C synonymous_variant 0.2
clpC1 4039112 c.1593C>G synonymous_variant 0.3
clpC1 4039118 c.1587C>G synonymous_variant 0.3
clpC1 4039121 c.1584T>C synonymous_variant 0.3
clpC1 4039142 c.1563A>G synonymous_variant 0.27
clpC1 4039145 c.1560G>C synonymous_variant 0.27
clpC1 4039169 p.Glu512Asp missense_variant 0.15
clpC1 4039183 c.1522T>C synonymous_variant 0.17
clpC1 4039187 c.1518G>C synonymous_variant 0.17
clpC1 4039430 c.1275T>C synonymous_variant 0.33
clpC1 4039442 c.1263A>G synonymous_variant 0.22
clpC1 4039448 c.1257A>G synonymous_variant 0.22
clpC1 4039454 c.1251A>T synonymous_variant 0.22
clpC1 4039616 c.1089G>C synonymous_variant 0.15
clpC1 4039622 c.1083C>T synonymous_variant 0.15
clpC1 4039640 c.1065C>G synonymous_variant 0.14
clpC1 4039649 c.1056G>C synonymous_variant 0.15
clpC1 4039652 c.1053G>C synonymous_variant 0.15
clpC1 4039661 c.1044T>C synonymous_variant 0.19
clpC1 4039664 c.1041G>C synonymous_variant 0.19
clpC1 4039694 c.1011G>C synonymous_variant 0.16
clpC1 4039718 c.987C>G synonymous_variant 0.17
clpC1 4039724 c.981A>G synonymous_variant 0.16
clpC1 4039733 c.972G>C synonymous_variant 0.15
clpC1 4040232 p.Arg158His missense_variant 0.2
clpC1 4040540 c.165G>C synonymous_variant 0.12
panD 4044037 p.Gly82Val missense_variant 0.22
panD 4044039 c.243G>T synonymous_variant 0.22
embC 4239978 p.Leu39Pro missense_variant 0.17
embC 4240324 c.462G>T synonymous_variant 0.14
embC 4240425 p.Arg188Pro missense_variant 0.2
embC 4240819 c.957A>C synonymous_variant 0.33
embC 4240822 c.960C>G synonymous_variant 0.33
embC 4240831 c.969T>G synonymous_variant 0.33
embC 4240934 p.Val358Ile missense_variant 0.2
embC 4240945 c.1083T>C synonymous_variant 0.2
embC 4240954 c.1092T>C synonymous_variant 0.2
embC 4241434 p.Met524Ile missense_variant 0.2
embC 4242545 p.Glu895* stop_gained 0.25
embC 4242794 p.Ala978Ser missense_variant 0.13
embC 4243065 p.Pro1068His missense_variant 0.18
embC 4243073 p.Gln1071Lys missense_variant 0.17
embA 4243078 c.-155C>A upstream_gene_variant 0.17
embA 4244272 p.Leu347Pro missense_variant 0.17
embA 4244486 c.1254C>A synonymous_variant 0.18
embA 4245009 p.Ala593Ser missense_variant 0.17
embA 4245230 p.Phe666Leu missense_variant 0.29
embA 4246180 p.Thr983Ile missense_variant 0.12
embB 4247176 c.663G>T synonymous_variant 0.14
embB 4247964 p.Ala484Val missense_variant 0.2
embB 4248705 p.Pro731Gln missense_variant 0.14
embB 4248957 p.Trp815Leu missense_variant 0.29
embB 4248986 p.Gly825Cys missense_variant 0.22
embB 4249167 p.Gly885Asp missense_variant 0.18
embB 4249299 p.Trp929Leu missense_variant 0.15
embB 4249596 p.Trp1028Leu missense_variant 0.2
embB 4249666 c.3153C>A synonymous_variant 0.2
aftB 4267181 c.1656C>A synonymous_variant 0.13
aftB 4267222 p.Ala539Ser missense_variant 0.15
aftB 4267263 p.Arg525Leu missense_variant 0.2
aftB 4267329 p.Arg503Leu missense_variant 0.15
aftB 4267641 p.Ala399Asp missense_variant 0.15
aftB 4267969 p.Leu290Met missense_variant 0.14
aftB 4268258 c.579C>A synonymous_variant 0.17
aftB 4268614 p.Gly75Trp missense_variant 0.25
ubiA 4269069 p.Phe255Leu missense_variant 0.14
aftB 4269117 c.-281G>A upstream_gene_variant 0.15
ubiA 4269120 p.Phe238Leu missense_variant 0.17
aftB 4269123 c.-287T>G upstream_gene_variant 0.17
aftB 4269129 c.-293G>C upstream_gene_variant 0.17
aftB 4269141 c.-307_-305delTTGinsCTC upstream_gene_variant 0.25
aftB 4269144 c.-308C>G upstream_gene_variant 0.22
ubiA 4269149 p.Val229Leu missense_variant 0.22
aftB 4269156 c.-320C>A upstream_gene_variant 0.22
aftB 4269171 c.-335C>G upstream_gene_variant 0.25
aftB 4269177 c.-341G>C upstream_gene_variant 0.25
ubiA 4269186 p.Thr216Ser missense_variant 0.29
ubiA 4269199 p.Ser212Asn missense_variant 0.29
aftB 4269201 c.-365A>G upstream_gene_variant 0.29
aftB 4269210 c.-374G>A upstream_gene_variant 0.33
ubiA 4269220 p.Ala205Lys missense_variant 0.29
aftB 4269222 c.-386T>C upstream_gene_variant 0.29
aftB 4269234 c.-398A>G upstream_gene_variant 0.29
ubiA 4269238 p.Ala199Val missense_variant 0.29
aftB 4269240 c.-404G>C upstream_gene_variant 0.29
ubiA 4269243 p.His197Gln missense_variant 0.29
aftB 4269249 c.-413G>A upstream_gene_variant 0.29
aftB 4269258 c.-422C>T upstream_gene_variant 0.29
aftB 4269264 c.-428C>T upstream_gene_variant 0.25
aftB 4269375 c.-539G>A upstream_gene_variant 0.2
ubiA 4269695 p.Asp47Tyr missense_variant 0.22
ubiA 4269756 p.Trp26Cys missense_variant 0.2
ubiA 4269924 c.-91G>A upstream_gene_variant 0.14
ethA 4326570 p.Phe302Leu missense_variant 0.33
ethR 4326907 c.-642C>G upstream_gene_variant 0.2
ethA 4327428 p.Gly16Cys missense_variant 0.22
ethA 4327436 p.Gly13Val missense_variant 0.33
whiB6 4338193 p.Arg110Leu missense_variant 0.22
whiB6 4338215 p.Gly103Cys missense_variant 0.22
whiB6 4338319 p.Glu68Gly missense_variant 0.2
whiB6 4338324 c.198C>A synonymous_variant 0.2
whiB6 4338347 c.175C>A synonymous_variant 0.2
whiB6 4338692 c.-171G>T upstream_gene_variant 0.2
gid 4407588 c.615A>G synonymous_variant 0.19
gid 4407942 p.Gln87His missense_variant 0.22