TB-Profiler result

Run: ERR2027220
Summary

Run ID: ERR2027220

Sample name:

Date: 31-03-2023 15:39:56

Number of reads: 362489

Percentage reads mapped: 84.39

Strain: lineage3.1.3

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
lineage3.1.3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
gyrB 6742 p.Glu501Asp missense_variant 0.15 ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.15 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.27 kanamycin, capreomycin, aminoglycosides, amikacin
pncA 2288847 p.Gly132Asp missense_variant 0.17 pyrazinamide
gid 4408125 c.77delT frameshift_variant 1.0 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5465 p.Glu76Gln missense_variant 0.17
gyrB 5656 c.417C>T synonymous_variant 0.2
gyrB 5833 c.594G>T synonymous_variant 0.22
gyrB 6656 p.Ser473Thr missense_variant 0.17
gyrA 7273 c.-29_-28insT upstream_gene_variant 0.2
gyrA 7343 c.42G>A synonymous_variant 0.25
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9162 p.Pro621Ser missense_variant 0.12
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9630 p.Val777Leu missense_variant 0.11
fgd1 491629 p.Arg283Cys missense_variant 0.11
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575370 p.Asp8Ala missense_variant 0.29
mshA 575397 p.Arg17His missense_variant 0.25
mshA 575540 p.Ala65Pro missense_variant 0.15
mshA 575681 p.Val112Leu missense_variant 0.17
mshA 575741 p.Phe132Val missense_variant 0.15
mshA 575810 p.Tyr155His missense_variant 0.17
mshA 575933 p.Pro196Ala missense_variant 0.12
mshA 576015 p.Gln223Arg missense_variant 0.14
mshA 576727 c.1380A>C synonymous_variant 0.4
ccsA 619698 c.-193G>A upstream_gene_variant 0.29
ccsA 620700 c.810C>G synonymous_variant 1.0
rpoB 761175 p.Leu457Val missense_variant 0.11
rpoB 762042 p.Ile746Phe missense_variant 0.14
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoB 762927 p.Gly1041Trp missense_variant 0.17
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 765193 p.Glu608Asp missense_variant 0.22
rpoC 765270 p.Lys634Arg missense_variant 0.18
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776240 c.2241G>A synonymous_variant 0.13
mmpL5 776492 c.1988delA frameshift_variant 0.17
mmpL5 777537 p.Leu315Pro missense_variant 0.14
mmpL5 777747 p.Gly245Glu missense_variant 0.2
mmpL5 777818 c.663G>C synonymous_variant 0.12
mmpL5 778455 p.Pro9Gln missense_variant 0.11
mmpS5 778841 p.Gly22Val missense_variant 0.13
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801195 c.387G>A synonymous_variant 0.15
rplC 801241 p.His145Tyr missense_variant 0.15
fbiC 1302994 p.Asn22Tyr missense_variant 0.29
fbiC 1303589 p.Arg220Gln missense_variant 0.25
fbiC 1304037 c.1107G>T synonymous_variant 0.12
fbiC 1304091 p.Asp387Glu missense_variant 0.13
fbiC 1304111 p.Ala394Glu missense_variant 0.15
Rv1258c 1407379 c.-39C>T upstream_gene_variant 0.18
embR 1416564 p.Ala262Thr missense_variant 0.12
embR 1417099 c.249C>A synonymous_variant 0.14
atpE 1461186 p.Arg48Trp missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.11
rrs 1471929 n.84C>G non_coding_transcript_exon_variant 0.11
rrs 1471967 n.122G>A non_coding_transcript_exon_variant 0.17
rrs 1471980 n.135G>C non_coding_transcript_exon_variant 0.17
rrs 1471981 n.136C>A non_coding_transcript_exon_variant 0.17
rrs 1472017 n.172C>T non_coding_transcript_exon_variant 0.18
rrs 1472027 n.184_188delCGGGA non_coding_transcript_exon_variant 0.11
rrs 1472035 n.190G>C non_coding_transcript_exon_variant 0.11
rrs 1472041 n.196C>G non_coding_transcript_exon_variant 0.22
rrs 1472043 n.198T>G non_coding_transcript_exon_variant 0.12
rrs 1472044 n.199G>A non_coding_transcript_exon_variant 0.12
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.13
rrs 1472057 n.212C>T non_coding_transcript_exon_variant 0.13
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.15
rrs 1472062 n.217G>T non_coding_transcript_exon_variant 0.15
rrs 1472067 n.222G>T non_coding_transcript_exon_variant 0.15
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.17
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.17
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.33
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.15
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.25
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.25
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.11
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.11
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.29
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.12
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.13
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.29
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.11
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.22
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.35
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.12
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.12
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.12
rrs 1472286 n.441C>A non_coding_transcript_exon_variant 0.12
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.12
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.12
rrs 1472297 n.453_461delGTCCGGGTT non_coding_transcript_exon_variant 0.12
rrs 1472309 n.464C>T non_coding_transcript_exon_variant 0.12
rrs 1472311 n.466C>T non_coding_transcript_exon_variant 0.12
rrs 1472312 n.468_470delGAT non_coding_transcript_exon_variant 0.14
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.17
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.17
rrs 1472328 n.483G>T non_coding_transcript_exon_variant 0.17
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 0.17
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.31
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.17
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.15
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.15
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.15
rrs 1472434 n.589_590insC non_coding_transcript_exon_variant 0.11
rrs 1472437 n.592T>C non_coding_transcript_exon_variant 0.11
rrs 1472438 n.594delC non_coding_transcript_exon_variant 0.11
rrs 1472446 n.601T>G non_coding_transcript_exon_variant 0.11
rrs 1472447 n.602C>G non_coding_transcript_exon_variant 0.12
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.11
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.11
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.11
rrs 1472459 n.614_615insCCCG non_coding_transcript_exon_variant 0.11
rrs 1472467 n.622G>T non_coding_transcript_exon_variant 0.11
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.11
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.11
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.12
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.14
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.14
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.14
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.15
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.15
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.2
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.24
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.12
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.29
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.19
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.17
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.17
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.12
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.12
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.16
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.12
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.16
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.14
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.14
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.15
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.14
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.13
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.17
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.18
rrs 1472837 n.992C>T non_coding_transcript_exon_variant 0.18
rrs 1472843 n.998_999insT non_coding_transcript_exon_variant 0.15
rrs 1472846 n.1002delG non_coding_transcript_exon_variant 0.15
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.15
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.15
rrs 1472855 n.1011_1012insGT non_coding_transcript_exon_variant 0.16
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 0.14
rrs 1472878 n.1033G>A non_coding_transcript_exon_variant 0.17
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.17
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.27
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.13
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.13
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.13
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.2
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.19
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.18
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.12
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.15
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.26
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.27
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.27
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.25
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.18
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.18
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.19
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.19
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.18
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.18
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.18
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.18
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.17
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.17
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.12
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.27
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.3
rrl 1473418 n.-240G>T upstream_gene_variant 0.14
rrl 1473568 n.-90G>T upstream_gene_variant 0.18
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.12
rrl 1474171 n.514C>T non_coding_transcript_exon_variant 0.16
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.18
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.18
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.18
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.15
rrl 1474199 n.542G>A non_coding_transcript_exon_variant 0.15
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.16
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.16
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.18
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.19
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.19
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.19
rrl 1474284 n.631_633delCCT non_coding_transcript_exon_variant 0.22
rrl 1474293 n.637_651delCCTCTCCGGAGGAGG non_coding_transcript_exon_variant 0.26
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.26
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.26
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.26
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.24
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.24
rrl 1474353 n.696A>T non_coding_transcript_exon_variant 0.24
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.22
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.22
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.21
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.21
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.15
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.18
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.17
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.18
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.18
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.21
rrl 1474883 n.1226T>C non_coding_transcript_exon_variant 0.23
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.2
rrl 1475188 n.1531C>A non_coding_transcript_exon_variant 0.12
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.15
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.22
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.18
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.18
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.17
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.17
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.15
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.12
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.11
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.1
rrl 1475990 n.2333G>A non_coding_transcript_exon_variant 0.13
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.17
rrl 1476028 n.2372_2375delAACC non_coding_transcript_exon_variant 0.16
rrl 1476034 n.2377_2378insACAT non_coding_transcript_exon_variant 0.14
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.16
rrl 1476048 n.2391G>T non_coding_transcript_exon_variant 0.16
rrl 1476049 n.2392C>G non_coding_transcript_exon_variant 0.16
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.24
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.24
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.24
rrl 1476090 n.2434dupT non_coding_transcript_exon_variant 0.22
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.2
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 0.2
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.2
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.2
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.2
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.2
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.21
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.1
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.17
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.14
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.14
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.14
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.13
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.16
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.1
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.1
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.16
rrl 1476299 n.2642C>G non_coding_transcript_exon_variant 0.12
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.2
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.2
rrl 1476308 n.2651G>C non_coding_transcript_exon_variant 0.12
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.15
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.12
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.18
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.13
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.15
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.17
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.18
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.18
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.18
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.17
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.16
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.16
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.15
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.1
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.12
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.13
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.12
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.12
rrl 1476613 n.2956G>A non_coding_transcript_exon_variant 0.12
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.12
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.12
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.12
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.12
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.12
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.12
rrl 1476714 n.3057G>A non_coding_transcript_exon_variant 0.12
inhA 1674114 c.-88T>C upstream_gene_variant 0.12
fabG1 1674118 p.Glu227Lys missense_variant 0.12
inhA 1674411 c.210C>T synonymous_variant 0.12
rpsA 1834159 c.618G>A synonymous_variant 1.0
rpsA 1834733 p.Ala398Thr missense_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101807 c.1236C>A synonymous_variant 0.12
ndh 2102400 p.Asp215Tyr missense_variant 0.22
ndh 2102943 p.Lys34* stop_gained 0.17
katG 2154472 p.Gly547Asp missense_variant 0.11
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2154863 p.His417Asn missense_variant 0.17
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168028 p.Pro862His missense_variant 0.11
PPE35 2168644 p.Phe657Leu missense_variant 0.11
Rv1979c 2222223 c.942C>G synonymous_variant 0.14
Rv1979c 2222445 c.720C>T synonymous_variant 0.14
Rv1979c 2222732 c.432delT frameshift_variant 1.0
Rv1979c 2223131 p.His12Asn missense_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288814 p.Ala143Val missense_variant 0.17
pncA 2289365 c.-125delC upstream_gene_variant 1.0
pncA 2289455 c.-214G>C upstream_gene_variant 1.0
kasA 2518557 p.Asn148Ile missense_variant 0.22
kasA 2518648 p.Ile178Met missense_variant 0.2
eis 2715014 p.Arg107Cys missense_variant 0.18
eis 2715058 p.Arg92Leu missense_variant 0.15
ahpC 2726000 c.-193T>A upstream_gene_variant 0.2
ahpC 2726003 c.-190C>A upstream_gene_variant 0.2
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
folC 2746176 p.Ala475Pro missense_variant 0.22
folC 2746876 c.723C>T synonymous_variant 1.0
folC 2747425 c.174C>G synonymous_variant 0.17
pepQ 2859990 c.429G>T synonymous_variant 0.11
ribD 2987128 p.Arg97Gln missense_variant 0.12
Rv2752c 3064886 p.Ala436Ser missense_variant 0.12
Rv2752c 3065860 p.Leu111Arg missense_variant 1.0
Rv2752c 3067106 c.-915G>C upstream_gene_variant 0.17
thyA 3073685 p.Val263Leu missense_variant 0.33
thyA 3073739 p.Asp245Tyr missense_variant 0.13
thyA 3074091 c.380delG frameshift_variant 0.12
thyA 3074419 p.Lys18Arg missense_variant 0.25
thyA 3074645 c.-174T>G upstream_gene_variant 0.25
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087156 p.Thr113Ser missense_variant 0.22
Rv3083 3448950 p.Tyr149* stop_gained 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474790 p.Pro262Thr missense_variant 0.15
fprA 3474904 p.Gly300Trp missense_variant 0.13
whiB7 3568464 c.216C>T synonymous_variant 0.18
Rv3236c 3612853 p.His88Gln missense_variant 0.12
fbiA 3640549 p.Val3Phe missense_variant 0.2
fbiB 3642692 c.1158C>G synonymous_variant 0.25
alr 3840566 p.Lys285Ser missense_variant 0.12
alr 3840923 c.498C>A synonymous_variant 0.13
alr 3841184 p.Gln79His missense_variant 0.33
alr 3841207 p.His72Tyr missense_variant 1.0
alr 3841218 p.Asp68Val missense_variant 0.18
rpoA 3878046 c.462T>C synonymous_variant 0.15
rpoA 3878204 p.Pro102Ala missense_variant 0.12
rpoA 3878504 p.Leu2Met missense_variant 0.2
clpC1 4039199 c.1506C>A synonymous_variant 0.18
clpC1 4039384 p.Ala441Thr missense_variant 0.17
panD 4044115 c.166dupG frameshift_variant 0.4
panD 4044175 p.Ala36Asp missense_variant 0.33
embC 4239878 c.20dupC frameshift_variant 0.11
embC 4241291 p.Leu477Met missense_variant 0.14
embC 4241953 c.2091G>A synonymous_variant 0.15
embC 4242075 p.Arg738Gln missense_variant 1.0
embC 4242402 p.Arg847Leu missense_variant 0.17
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243194 c.-39C>A upstream_gene_variant 0.12
embA 4245395 c.2163C>A synonymous_variant 0.12
embA 4245705 p.His825Asp missense_variant 0.33
embB 4246010 c.-504G>T upstream_gene_variant 0.22
embB 4247900 p.Leu463Met missense_variant 0.25
embB 4249195 c.2682C>A synonymous_variant 1.0
embB 4249756 c.3243C>A synonymous_variant 0.14
aftB 4267290 p.Ala516Val missense_variant 0.2
aftB 4267451 c.1386G>A synonymous_variant 0.17
aftB 4269576 c.-740C>A upstream_gene_variant 0.25
ethA 4326899 p.Pro192Leu missense_variant 0.17
ethR 4327715 p.Ile56Thr missense_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4408175 p.Ala10Pro missense_variant 1.0
gid 4408243 c.-44_-42delCAC upstream_gene_variant 0.2