TB-Profiler result

Run: ERR212015
Summary

Run ID: ERR212015

Sample name:

Date: 31-03-2023 15:44:31

Number of reads: 1436969

Percentage reads mapped: 72.0

Strain: lineage4.8

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 490751 c.-32T>G upstream_gene_variant 0.27
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303016 p.Val29Gly missense_variant 0.3
fbiC 1304159 p.Val410Gly missense_variant 0.29
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.23
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 0.24
rrs 1472129 n.284G>A non_coding_transcript_exon_variant 0.24
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.23
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.23
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.24
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.24
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.26
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.17
rrs 1472697 n.852T>G non_coding_transcript_exon_variant 0.27
rrs 1472700 n.855C>T non_coding_transcript_exon_variant 0.36
rrs 1472708 n.863T>A non_coding_transcript_exon_variant 0.47
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.67
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.66
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.61
rrs 1472786 n.941C>T non_coding_transcript_exon_variant 0.61
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.56
rrs 1472803 n.958T>C non_coding_transcript_exon_variant 0.48
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.2
rrs 1473147 n.1302G>C non_coding_transcript_exon_variant 0.28
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.27
rrs 1473150 n.1305T>G non_coding_transcript_exon_variant 0.24
rrs 1473161 n.1316A>C non_coding_transcript_exon_variant 0.32
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.32
rrs 1473164 n.1319C>G non_coding_transcript_exon_variant 0.32
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.53
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.53
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.53
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.49
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.49
rrs 1473262 n.1417T>A non_coding_transcript_exon_variant 0.5
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.2
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.12
rrl 1473407 n.-251A>C upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 0.26
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.27
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.27
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.27
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.27
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.27
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.27
rrl 1475869 n.2212C>T non_coding_transcript_exon_variant 0.26
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.34
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.41
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.48
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.52
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.49
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.48
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.48
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.48
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.5
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.54
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.53
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.55
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.62
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.64
rrl 1476353 n.2696G>A non_coding_transcript_exon_variant 0.66
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.65
rrl 1476359 n.2702C>T non_coding_transcript_exon_variant 0.65
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.7
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.7
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.77
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.78
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.78
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.77
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.68
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.67
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.65
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.61
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.45
rrl 1476513 n.2856G>A non_coding_transcript_exon_variant 0.23
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.22
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.18
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.17
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.17
rrl 1476544 n.2887T>C non_coding_transcript_exon_variant 0.1
rrl 1476545 n.2888C>T non_coding_transcript_exon_variant 0.12
rrl 1476565 n.2908G>A non_coding_transcript_exon_variant 0.28
rrl 1476566 n.2909A>G non_coding_transcript_exon_variant 0.28
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.28
rrl 1476577 n.2920T>A non_coding_transcript_exon_variant 0.36
rrl 1476578 n.2921C>A non_coding_transcript_exon_variant 0.35
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.36
rrl 1476592 n.2935G>A non_coding_transcript_exon_variant 0.36
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.36
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.33
rrl 1476605 n.2948C>T non_coding_transcript_exon_variant 0.33
rrl 1476608 n.2951C>A non_coding_transcript_exon_variant 0.33
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 0.36
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.35
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.36
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.36
rrl 1476637 n.2980C>A non_coding_transcript_exon_variant 0.37
rrl 1476657 n.3000G>T non_coding_transcript_exon_variant 0.16
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103202 c.-160C>A upstream_gene_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 0.96
PPE35 2169317 c.1296C>T synonymous_variant 0.21
PPE35 2169320 p.Leu431Phe missense_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2987307 p.Ala157Pro missense_variant 0.28
rpoA 3878565 c.-58G>C upstream_gene_variant 0.14
clpC1 4038857 c.1848C>A synonymous_variant 0.3
embC 4239842 c.-21C>A upstream_gene_variant 0.25
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247395 c.882C>T synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0