TB-Profiler result

Run: ERR2660545
Summary

Run ID: ERR2660545

Sample name:

Date: 31-03-2023 22:55:06

Number of reads: 4992641

Percentage reads mapped: 88.84

Strain: lineage4.3.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.2 Euro-American (LAM) LAM3 None 1.0
lineage4.3.2.1 Euro-American (LAM) LAM3 RD761 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5520 p.Pro94Leu missense_variant 1.0
gyrA 7222 c.-80C>T upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.1
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.1
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.13
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 1.0
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.17
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.19
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.19
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.24
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.31
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.35
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.36
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.35
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.34
rrs 1472659 n.814G>A non_coding_transcript_exon_variant 0.34
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.34
rrs 1472669 n.824_825insTAG non_coding_transcript_exon_variant 0.35
rrs 1472677 n.832C>G non_coding_transcript_exon_variant 0.34
rrs 1472678 n.833T>A non_coding_transcript_exon_variant 0.34
rrs 1472679 n.834_835insAC non_coding_transcript_exon_variant 0.34
rrs 1472684 n.841_846delGATCCG non_coding_transcript_exon_variant 0.33
rrs 1472697 n.852T>A non_coding_transcript_exon_variant 0.33
rrs 1472700 n.855C>T non_coding_transcript_exon_variant 0.33
rrs 1472705 n.860G>A non_coding_transcript_exon_variant 0.32
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.33
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 0.33
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.34
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.4
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.39
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.4
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.4
rrs 1472779 n.934G>A non_coding_transcript_exon_variant 0.34
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.32
rrs 1472786 n.941C>T non_coding_transcript_exon_variant 0.27
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.21
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.21
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.14
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.13
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.11
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.12
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.12
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.12
rrl 1474913 n.1256T>A non_coding_transcript_exon_variant 0.12
rrl 1475150 n.1493C>T non_coding_transcript_exon_variant 1.0
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.14
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.19
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.19
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.19
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.19
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.19
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.2
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.2
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.2
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.2
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.2
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.2
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.22
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.23
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.26
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.31
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.31
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.32
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.32
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.32
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.32
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.32
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.31
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.31
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.31
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.32
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.32
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.35
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.34
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.39
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.36
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.34
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.33
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.34
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.37
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.31
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.31
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.26
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.22
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.17
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.13
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.13
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.13
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.13
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.13
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.13
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.13
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.13
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.13
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.13
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.13
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.13
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.15
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.16
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.17
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.16
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 0.99
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878578 c.-71C>A upstream_gene_variant 0.33
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0