TB-Profiler result

Run: SRR6785262
Summary

Run ID: SRR6785262

Sample name:

Date: 04-04-2023 15:40:31

Number of reads: 1269697

Percentage reads mapped: 81.71

Strain: lineage4.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.98
lineage4.2 Euro-American H;T;LAM None 0.94
lineage4.2.1 Euro-American (TUR) H3;H4 None 0.94
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6238 c.999G>A synonymous_variant 0.24
gyrB 6242 p.Arg335Lys missense_variant 0.21
gyrB 6250 c.1011A>G synonymous_variant 0.19
gyrB 6256 c.1017G>A synonymous_variant 0.18
gyrB 6265 c.1026C>T synonymous_variant 0.15
gyrB 6268 c.1029C>G synonymous_variant 0.18
gyrB 6280 c.1041T>C synonymous_variant 0.15
gyrB 6289 c.1050C>T synonymous_variant 0.12
gyrA 6577 c.-725T>C upstream_gene_variant 0.17
gyrA 6580 c.-722C>G upstream_gene_variant 0.15
gyrA 6598 c.-704C>G upstream_gene_variant 0.21
gyrA 6610 c.-692C>G upstream_gene_variant 0.23
gyrA 6613 c.-689A>G upstream_gene_variant 0.24
gyrA 6616 c.-686A>G upstream_gene_variant 0.24
gyrA 6622 c.-680C>T upstream_gene_variant 0.26
gyrA 6634 c.-668T>C upstream_gene_variant 0.24
gyrA 6637 c.-665T>G upstream_gene_variant 0.25
gyrA 6640 c.-662A>G upstream_gene_variant 0.22
gyrA 6649 c.-653T>C upstream_gene_variant 0.27
gyrA 6655 c.-647T>C upstream_gene_variant 0.3
gyrA 6670 c.-632G>C upstream_gene_variant 0.25
gyrA 6673 c.-629A>C upstream_gene_variant 0.26
gyrA 6676 c.-626T>G upstream_gene_variant 0.27
gyrA 6700 c.-602T>C upstream_gene_variant 0.29
gyrA 6703 c.-599G>C upstream_gene_variant 0.28
gyrA 6709 c.-593A>G upstream_gene_variant 0.3
gyrA 6712 c.-590G>C upstream_gene_variant 0.33
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.26
gyrA 6742 c.-560A>G upstream_gene_variant 0.24
gyrA 6745 c.-557T>G upstream_gene_variant 0.21
gyrA 6751 c.-551G>C upstream_gene_variant 0.19
gyrA 6760 c.-542G>C upstream_gene_variant 0.18
gyrA 6763 c.-539G>C upstream_gene_variant 0.17
gyrA 6775 c.-527G>C upstream_gene_variant 0.18
gyrA 6793 c.-509T>C upstream_gene_variant 0.2
gyrB 6797 p.Gly520Thr missense_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8619 c.1318T>C synonymous_variant 0.16
gyrA 8624 c.1323G>C synonymous_variant 0.17
gyrA 8636 c.1335A>C synonymous_variant 0.2
gyrA 8642 c.1341A>G synonymous_variant 0.17
gyrA 8672 c.1371A>G synonymous_variant 0.18
gyrA 8678 c.1377G>A synonymous_variant 0.22
gyrA 8693 c.1392T>C synonymous_variant 0.21
gyrA 8696 c.1395G>C synonymous_variant 0.21
gyrA 8699 c.1398A>G synonymous_variant 0.2
gyrA 8711 c.1410A>C synonymous_variant 0.22
gyrA 8714 c.1413A>G synonymous_variant 0.23
gyrA 8729 c.1428T>C synonymous_variant 0.17
gyrA 8740 p.Arg480His missense_variant 0.17
gyrA 8816 c.1515C>G synonymous_variant 0.15
gyrA 8818 p.Ser506Asn missense_variant 0.16
gyrA 8828 c.1527T>C synonymous_variant 0.14
gyrA 8867 c.1566A>G synonymous_variant 0.23
gyrA 8870 c.1569G>C synonymous_variant 0.22
gyrA 8873 c.1572A>C synonymous_variant 0.21
gyrA 8891 c.1590G>A synonymous_variant 0.21
gyrA 8897 c.1596T>C synonymous_variant 0.2
gyrA 8903 c.1602T>C synonymous_variant 0.19
gyrA 8933 c.1632G>C synonymous_variant 0.13
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491130 c.348C>G synonymous_variant 0.13
fgd1 491144 p.Ala121Asp missense_variant 0.16
fgd1 491151 c.369G>A synonymous_variant 0.15
fgd1 491247 c.465C>T synonymous_variant 0.88
fgd1 491259 c.477T>C synonymous_variant 0.13
mshA 575659 c.312A>G synonymous_variant 0.13
mshA 575662 c.315C>G synonymous_variant 0.13
mshA 575752 c.405G>C synonymous_variant 0.14
mshA 575824 c.477T>G synonymous_variant 0.14
mshA 575830 c.483C>G synonymous_variant 0.14
mshA 575833 c.486C>G synonymous_variant 0.14
mshA 575845 c.498C>T synonymous_variant 0.15
mshA 575907 p.Ala187Val missense_variant 0.17
rpoB 760101 c.295T>C synonymous_variant 0.17
rpoB 760112 c.306T>C synonymous_variant 0.2
rpoB 760118 c.312T>G synonymous_variant 0.22
rpoB 760121 c.315T>C synonymous_variant 0.2
rpoB 760130 p.Asp108Glu missense_variant 0.19
rpoB 760139 c.333A>G synonymous_variant 0.22
rpoB 760142 c.336C>G synonymous_variant 0.2
rpoB 760181 c.375T>C synonymous_variant 0.18
rpoB 760184 c.378A>G synonymous_variant 0.17
rpoB 760196 c.390C>G synonymous_variant 0.16
rpoB 760223 c.417T>C synonymous_variant 0.14
rpoB 760298 c.492G>C synonymous_variant 0.13
rpoB 760376 p.Asp190Glu missense_variant 0.15
rpoB 760380 p.Thr192Leu missense_variant 0.15
rpoB 760406 c.600G>C synonymous_variant 0.18
rpoB 760412 c.606C>G synonymous_variant 0.2
rpoB 760424 c.618C>G synonymous_variant 0.19
rpoB 760430 c.624T>C synonymous_variant 0.22
rpoB 760475 c.669A>G synonymous_variant 0.27
rpoB 760481 c.675G>C synonymous_variant 0.29
rpoB 760484 c.678A>G synonymous_variant 0.29
rpoB 760522 p.Ser239Asn missense_variant 0.27
rpoB 760532 c.726T>C synonymous_variant 0.23
rpoB 760533 p.Val243Thr missense_variant 0.23
rpoB 760541 c.735G>C synonymous_variant 0.27
rpoB 760547 c.741G>C synonymous_variant 0.28
rpoB 760563 p.Arg253Met missense_variant 0.22
rpoB 760591 p.Val262Ala missense_variant 0.27
rpoB 760595 c.789C>T synonymous_variant 0.13
rpoB 760598 c.792C>A synonymous_variant 0.13
rpoB 760611 c.805T>C synonymous_variant 0.22
rpoB 760646 c.840C>G synonymous_variant 0.14
rpoB 760655 c.849A>G synonymous_variant 0.15
rpoB 760946 c.1140A>G synonymous_variant 0.17
rpoB 760982 c.1176G>C synonymous_variant 0.2
rpoB 760985 c.1179G>C synonymous_variant 0.21
rpoB 760991 c.1185G>C synonymous_variant 0.2
rpoB 761006 c.1200C>G synonymous_variant 0.2
rpoB 761015 c.1209G>C synonymous_variant 0.18
rpoB 761021 c.1215G>C synonymous_variant 0.2
rpoB 761027 c.1221A>G synonymous_variant 0.15
rpoB 761036 c.1230G>C synonymous_variant 0.14
rpoB 761037 c.1231T>C synonymous_variant 0.14
rpoB 761150 c.1344A>C synonymous_variant 0.17
rpoB 761153 c.1347G>C synonymous_variant 0.14
rpoB 761657 c.1851C>G synonymous_variant 0.14
rpoC 762989 c.-381G>C upstream_gene_variant 0.14
rpoC 762995 c.-375G>T upstream_gene_variant 0.15
rpoC 763013 c.-357C>G upstream_gene_variant 0.17
rpoC 763040 c.-330C>G upstream_gene_variant 0.16
rpoC 763070 c.-300T>C upstream_gene_variant 0.19
rpoC 763085 c.-285C>G upstream_gene_variant 0.15
rpoC 763441 c.72C>T synonymous_variant 0.2
rpoC 763444 c.75T>C synonymous_variant 0.2
rpoC 763456 c.87A>G synonymous_variant 0.28
rpoC 763486 c.117T>G synonymous_variant 0.28
rpoC 763528 c.159G>A synonymous_variant 0.28
rpoC 763546 c.177A>G synonymous_variant 0.31
rpoC 763570 c.201G>C synonymous_variant 0.29
rpoC 763573 c.204G>C synonymous_variant 0.28
rpoC 763594 c.225C>T synonymous_variant 0.26
rpoC 763603 c.234C>T synonymous_variant 0.24
rpoC 763636 c.267T>C synonymous_variant 0.23
rpoC 763660 c.291T>G synonymous_variant 0.24
rpoC 763675 c.306C>G synonymous_variant 0.23
rpoC 763696 c.327T>C synonymous_variant 0.16
rpoC 763702 c.333C>G synonymous_variant 0.18
rpoC 763717 c.348T>C synonymous_variant 0.21
rpoC 763723 c.354G>C synonymous_variant 0.18
rpoC 763732 c.363C>G synonymous_variant 0.18
rpoC 763741 c.372C>T synonymous_variant 0.15
rpoC 763744 c.375G>C synonymous_variant 0.15
rpoC 763765 c.396T>C synonymous_variant 0.17
rpoC 763774 c.405G>C synonymous_variant 0.18
rpoC 763987 c.618C>T synonymous_variant 0.15
rpoC 763991 p.Ile208Leu missense_variant 0.15
rpoC 763996 c.627T>C synonymous_variant 0.14
rpoC 764002 c.633C>G synonymous_variant 0.15
rpoC 764005 c.636G>C synonymous_variant 0.16
rpoC 764044 c.675T>C synonymous_variant 0.17
rpoC 764059 c.690G>T synonymous_variant 0.18
rpoC 764083 c.714A>G synonymous_variant 0.16
rpoC 764116 c.747C>T synonymous_variant 0.14
rpoC 764131 c.762T>C synonymous_variant 0.16
rpoC 764140 c.771C>T synonymous_variant 0.17
rpoC 764188 c.819A>G synonymous_variant 0.15
rpoC 764195 p.Ser276Ile missense_variant 0.15
rpoC 764203 c.834G>C synonymous_variant 0.16
rpoC 764206 c.837T>C synonymous_variant 0.2
rpoC 764215 c.846A>G synonymous_variant 0.21
rpoC 764236 c.867G>A synonymous_variant 0.19
rpoC 764248 c.879C>G synonymous_variant 0.2
rpoC 764257 c.888G>C synonymous_variant 0.18
rpoC 764266 c.897T>C synonymous_variant 0.14
rpoC 764269 c.900G>C synonymous_variant 0.14
rpoC 764278 c.909A>G synonymous_variant 0.15
rpoC 764338 c.969G>A synonymous_variant 0.16
rpoC 764419 c.1050C>G synonymous_variant 0.19
rpoC 764428 c.1059G>C synonymous_variant 0.2
rpoC 764431 c.1062G>C synonymous_variant 0.17
rpoC 764434 c.1065A>G synonymous_variant 0.17
rpoC 764446 c.1077T>C synonymous_variant 0.15
rpoC 764449 c.1080G>C synonymous_variant 0.15
rpoC 764452 c.1083T>C synonymous_variant 0.15
rpoC 764458 c.1089G>C synonymous_variant 0.15
rpoC 764461 c.1092A>G synonymous_variant 0.15
rpoC 764489 c.1120C>T synonymous_variant 0.18
rpoC 764497 c.1128A>G synonymous_variant 0.22
rpoC 764510 c.1141C>T synonymous_variant 0.18
rpoC 764521 c.1152T>C synonymous_variant 0.17
rpoC 764527 c.1158C>T synonymous_variant 0.16
rpoC 764536 c.1167G>C synonymous_variant 0.17
rpoC 764539 c.1170C>G synonymous_variant 0.16
rpoC 764554 c.1185C>T synonymous_variant 0.22
rpoC 764560 c.1191T>C synonymous_variant 0.21
rpoC 764566 c.1197C>G synonymous_variant 0.18
rpoC 764575 c.1206T>G synonymous_variant 0.16
rpoC 764581 c.1212T>C synonymous_variant 0.15
rpoC 764593 c.1224C>T synonymous_variant 0.14
rpoC 764752 c.1383G>C synonymous_variant 0.2
rpoC 764764 c.1395T>C synonymous_variant 0.2
rpoC 764809 c.1440C>T synonymous_variant 0.21
rpoC 764815 c.1446A>G synonymous_variant 0.18
rpoC 764827 c.1458G>C synonymous_variant 0.21
rpoC 764858 c.1489T>C synonymous_variant 0.18
rpoC 764872 c.1503A>G synonymous_variant 0.15
rpoC 765478 c.2109T>C synonymous_variant 0.27
rpoC 765499 c.2130C>G synonymous_variant 0.18
rpoC 765529 c.2160C>T synonymous_variant 0.18
rpoC 765541 c.2172C>G synonymous_variant 0.19
rpoC 765553 c.2184C>T synonymous_variant 0.13
rpoC 765700 c.2331T>C synonymous_variant 0.19
rpoC 765982 c.2613C>G synonymous_variant 0.14
rpoC 765994 c.2625A>T synonymous_variant 0.14
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.15
rpoC 766021 c.2652G>C synonymous_variant 0.16
rpoC 766027 c.2658G>C synonymous_variant 0.15
rpoC 766327 c.2958C>A synonymous_variant 0.14
rpoC 766345 c.2976T>C synonymous_variant 0.15
rpoC 766348 c.2979A>G synonymous_variant 0.15
rpoC 766357 c.2988C>T synonymous_variant 0.15
rpoC 766363 c.2994G>C synonymous_variant 0.15
rpoC 766381 c.3012C>T synonymous_variant 0.15
rpoC 766384 c.3015A>G synonymous_variant 0.15
rpoC 766426 c.3057C>T synonymous_variant 0.21
rpoC 766447 c.3078T>C synonymous_variant 0.21
rpoC 766462 c.3093G>C synonymous_variant 0.19
rpoC 766522 c.3153C>G synonymous_variant 0.15
rpoC 766528 c.3159T>C synonymous_variant 0.18
rpoC 766531 c.3162G>C synonymous_variant 0.18
rpoC 766540 p.Asp1057Glu missense_variant 0.23
rpoC 766573 c.3204T>C synonymous_variant 0.18
rpoC 766582 c.3213C>G synonymous_variant 0.14
rpoC 766583 p.Gly1072Ser missense_variant 0.15
rpoC 766594 c.3225G>C synonymous_variant 0.14
rpoC 766597 c.3228C>G synonymous_variant 0.14
rpoC 766607 p.Ile1080Leu missense_variant 0.15
rpoC 766738 c.3369G>C synonymous_variant 0.17
rpoC 766765 c.3396A>C synonymous_variant 0.2
rpoC 766774 c.3405T>C synonymous_variant 0.17
rpoC 766801 c.3432C>G synonymous_variant 0.32
rpoC 766804 c.3435A>G synonymous_variant 0.32
rpoC 766861 c.3492G>C synonymous_variant 0.27
rpoC 766864 c.3495G>C synonymous_variant 0.27
rpoC 766867 c.3498C>G synonymous_variant 0.24
rpoC 766933 c.3564A>G synonymous_variant 0.16
rpoC 766945 c.3576A>G synonymous_variant 0.15
rpoC 766963 c.3594T>C synonymous_variant 0.18
rpoC 766972 c.3603G>C synonymous_variant 0.17
rpoC 766996 c.3627C>T synonymous_variant 0.17
rpoC 767033 p.Ser1222Thr missense_variant 0.12
rpoC 767059 c.3690T>G synonymous_variant 0.21
rpoC 767062 c.3693C>A synonymous_variant 0.22
rpoC 767098 c.3729T>C synonymous_variant 0.26
rpoC 767119 c.3750A>G synonymous_variant 0.21
rpoC 767134 c.3765C>A synonymous_variant 0.21
rpoC 767158 c.3789T>C synonymous_variant 0.24
rpoC 767180 p.Ala1271Gln missense_variant 0.21
rpoC 767191 c.3822C>G synonymous_variant 0.19
rpoC 767206 c.3837C>G synonymous_variant 0.17
rpoC 767209 c.3840T>C synonymous_variant 0.14
rpoC 767212 c.3843G>C synonymous_variant 0.14
mmpL5 775639 p.Ile948Val missense_variant 0.97
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781628 c.69T>C synonymous_variant 0.23
rpsL 781631 c.72G>C synonymous_variant 0.19
rpsL 781649 c.90T>C synonymous_variant 0.23
rpsL 781655 c.96T>C synonymous_variant 0.24
rpsL 781700 c.141G>C synonymous_variant 0.29
rpsL 781703 c.144G>T synonymous_variant 0.29
rpsL 781715 c.156T>C synonymous_variant 0.31
rpsL 781728 c.169T>C synonymous_variant 0.33
rpsL 781736 c.177T>C synonymous_variant 0.33
rpsL 781742 c.183C>T synonymous_variant 0.35
rpsL 781748 c.189C>G synonymous_variant 0.34
rpsL 781754 c.195G>C synonymous_variant 0.32
rpsL 781760 c.201T>C synonymous_variant 0.27
rpsL 781772 c.213C>A synonymous_variant 0.23
rpsL 781808 c.249C>T synonymous_variant 0.25
rpsL 781811 c.252C>T synonymous_variant 0.26
rpsL 781832 c.273T>C synonymous_variant 0.18
rpsL 781838 c.279G>C synonymous_variant 0.14
rpsL 781841 c.282C>G synonymous_variant 0.14
rpsL 781871 c.312G>C synonymous_variant 0.15
rpsL 781877 c.318T>C synonymous_variant 0.15
rpsL 781892 c.333A>G synonymous_variant 0.15
rpsL 781898 c.339A>T synonymous_variant 0.15
rpsL 781916 c.357T>C synonymous_variant 0.15
rpsL 781929 p.Gly124Ser missense_variant 0.16
rplC 800720 c.-89T>C upstream_gene_variant 0.14
rplC 800723 c.-86C>G upstream_gene_variant 0.15
rplC 800747 c.-62C>G upstream_gene_variant 0.16
fbiC 1303755 c.825T>C synonymous_variant 0.14
fbiC 1303761 c.831T>C synonymous_variant 0.15
fbiC 1303785 c.855G>C synonymous_variant 0.14
fbiC 1303789 p.Ile287Val missense_variant 0.17
fbiC 1303797 c.867A>G synonymous_variant 0.23
fbiC 1303818 c.888C>G synonymous_variant 0.25
fbiC 1303836 c.906G>C synonymous_variant 0.16
fbiC 1303846 p.Phe306Val missense_variant 0.16
fbiC 1303854 c.924T>C synonymous_variant 0.16
fbiC 1303860 c.930A>C synonymous_variant 0.15
fbiC 1303905 c.975G>C synonymous_variant 0.15
fbiC 1303914 c.984C>G synonymous_variant 0.15
fbiC 1303920 c.990C>T synonymous_variant 0.15
fbiC 1303980 c.1050G>A synonymous_variant 0.19
fbiC 1303998 c.1068T>G synonymous_variant 0.2
fbiC 1304004 c.1074A>G synonymous_variant 0.17
fbiC 1304008 c.1078T>C synonymous_variant 0.14
fbiC 1304022 c.1092T>C synonymous_variant 0.14
fbiC 1304031 c.1101C>G synonymous_variant 0.14
fbiC 1304034 c.1104A>G synonymous_variant 0.14
fbiC 1304553 c.1623C>T synonymous_variant 0.14
fbiC 1304559 p.Glu543Asp missense_variant 0.16
fbiC 1304565 c.1635C>G synonymous_variant 0.15
fbiC 1304568 c.1638T>C synonymous_variant 0.15
fbiC 1304613 c.1683T>C synonymous_variant 0.18
fbiC 1304634 c.1704C>G synonymous_variant 0.19
fbiC 1304640 c.1710A>C synonymous_variant 0.18
fbiC 1304646 c.1716T>C synonymous_variant 0.16
fbiC 1304658 c.1728C>G synonymous_variant 0.14
fbiC 1304983 c.2053C>T synonymous_variant 0.14
fbiC 1305033 c.2103T>G synonymous_variant 0.12
atpE 1461132 p.Val30Ile missense_variant 0.14
atpE 1461149 c.105T>G synonymous_variant 0.13
atpE 1461150 p.Ile36Val missense_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.24
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.23
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.18
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.26
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.14
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.13
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.13
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.19
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.15
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.17
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.14
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.19
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.18
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.18
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.16
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.14
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.14
inhA 1674672 c.471C>G synonymous_variant 0.13
inhA 1674703 c.502T>C synonymous_variant 0.14
inhA 1674801 c.600T>C synonymous_variant 0.14
inhA 1674816 c.615T>C synonymous_variant 0.13
inhA 1674870 c.669T>C synonymous_variant 0.14
inhA 1674879 c.678T>C synonymous_variant 0.13
inhA 1674903 c.702T>C synonymous_variant 0.13
rpsA 1833554 p.Thr5Ala missense_variant 0.15
rpsA 1833568 c.27G>C synonymous_variant 0.16
rpsA 1833589 c.48A>T synonymous_variant 0.26
rpsA 1833595 c.54T>C synonymous_variant 0.25
rpsA 1833661 c.120A>G synonymous_variant 0.18
rpsA 1833667 c.126C>G synonymous_variant 0.18
rpsA 1833721 c.180A>G synonymous_variant 0.19
rpsA 1833724 c.183C>G synonymous_variant 0.16
rpsA 1833727 c.186G>C synonymous_variant 0.16
rpsA 1833742 c.201A>G synonymous_variant 0.16
rpsA 1833748 c.207C>G synonymous_variant 0.14
rpsA 1833787 c.246C>G synonymous_variant 0.16
rpsA 1833790 c.249T>C synonymous_variant 0.16
rpsA 1833802 c.261A>G synonymous_variant 0.19
rpsA 1833811 c.270G>T synonymous_variant 0.17
rpsA 1833838 c.297G>C synonymous_variant 0.14
rpsA 1833841 c.300C>G synonymous_variant 0.14
rpsA 1833847 c.306C>G synonymous_variant 0.18
rpsA 1833856 c.315A>G synonymous_variant 0.19
rpsA 1833874 c.333T>C synonymous_variant 0.18
rpsA 1833886 c.345C>G synonymous_variant 0.18
rpsA 1834081 c.540C>T synonymous_variant 0.17
rpsA 1834096 c.555G>C synonymous_variant 0.16
rpsA 1834099 c.558C>G synonymous_variant 0.16
rpsA 1834102 c.561T>C synonymous_variant 0.17
rpsA 1834105 c.564C>G synonymous_variant 0.18
rpsA 1834108 c.567C>G synonymous_variant 0.18
rpsA 1834123 c.582C>G synonymous_variant 0.15
rpsA 1834177 c.636A>C synonymous_variant 0.16
rpsA 1834423 c.882G>C synonymous_variant 0.15
rpsA 1834435 c.894G>C synonymous_variant 0.18
rpsA 1834451 c.910T>C synonymous_variant 0.26
rpsA 1834465 c.924T>C synonymous_variant 0.24
rpsA 1834468 c.927A>G synonymous_variant 0.24
rpsA 1834489 c.948T>C synonymous_variant 0.24
rpsA 1834513 c.972C>G synonymous_variant 0.24
rpsA 1834528 c.987T>C synonymous_variant 0.26
rpsA 1834540 c.999G>C synonymous_variant 0.24
rpsA 1834546 c.1005T>C synonymous_variant 0.21
rpsA 1834555 c.1014T>G synonymous_variant 0.18
rpsA 1834609 c.1068T>C synonymous_variant 0.19
rpsA 1834618 c.1077G>C synonymous_variant 0.19
rpsA 1834633 c.1092A>G synonymous_variant 0.23
rpsA 1834639 c.1098T>C synonymous_variant 0.28
rpsA 1834654 p.Glu371Asp missense_variant 0.21
rpsA 1834690 c.1149T>C synonymous_variant 0.22
rpsA 1834732 c.1191T>C synonymous_variant 0.16
rpsA 1834733 p.Ala398Ser missense_variant 0.16
rpsA 1834738 c.1197A>G synonymous_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170308 p.Leu102Ala missense_variant 0.88
PPE35 2170313 c.300G>C synonymous_variant 0.88
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518864 c.750G>C synonymous_variant 0.16
kasA 2518879 c.765A>G synonymous_variant 0.15
kasA 2518885 c.771T>C synonymous_variant 0.16
kasA 2518898 c.784T>C synonymous_variant 0.17
kasA 2518906 c.792A>G synonymous_variant 0.18
kasA 2518910 p.Leu266Met missense_variant 0.14
kasA 2518921 c.807T>C synonymous_variant 0.15
kasA 2518927 c.813C>G synonymous_variant 0.16
kasA 2518936 c.822C>G synonymous_variant 0.16
kasA 2518939 c.825T>C synonymous_variant 0.13
kasA 2518942 c.828T>C synonymous_variant 0.13
folC 2747275 c.324T>C synonymous_variant 0.13
folC 2747289 p.Pro104Ala missense_variant 0.13
folC 2747290 c.309A>G synonymous_variant 0.13
folC 2747302 c.297A>C synonymous_variant 0.13
ribD 2986910 c.72C>A synonymous_variant 1.0
Rv2752c 3065048 c.1144C>T synonymous_variant 0.15
Rv2752c 3065052 c.1140G>A synonymous_variant 0.15
Rv2752c 3065055 c.1137T>C synonymous_variant 0.14
Rv2752c 3065064 c.1128G>C synonymous_variant 0.14
thyX 3067274 c.672C>G synonymous_variant 0.15
thyX 3067355 c.591A>C synonymous_variant 0.15
thyX 3067367 c.579G>C synonymous_variant 0.14
thyX 3067391 c.555G>C synonymous_variant 0.19
thyX 3067394 c.552G>C synonymous_variant 0.2
thyX 3067439 c.507A>G synonymous_variant 0.3
thyX 3067445 c.501C>G synonymous_variant 0.3
thyX 3067457 c.489C>G synonymous_variant 0.39
thyX 3067465 p.Ile161Val missense_variant 0.41
thyX 3067475 c.471A>G synonymous_variant 0.44
thyX 3067490 c.456C>G synonymous_variant 0.44
thyX 3067493 c.453A>G synonymous_variant 0.44
thyX 3067515 p.Ser144Thr missense_variant 0.42
thyX 3067530 p.Ala139Ser missense_variant 0.33
thyX 3067545 p.Glu134Ala missense_variant 0.32
thyX 3067549 p.Thr133Ala missense_variant 0.32
thyX 3067556 p.His130Gln missense_variant 0.33
thyX 3067559 c.387C>G synonymous_variant 0.35
thyX 3067565 p.Asp127Glu missense_variant 0.36
thyX 3067570 p.Ala126Pro missense_variant 0.33
thyX 3067577 c.369G>A synonymous_variant 0.32
thyX 3067583 c.363C>G synonymous_variant 0.31
thyX 3067601 p.Arg115His missense_variant 0.26
thyX 3067611 p.Lys112Thr missense_variant 0.26
thyX 3067619 c.327A>C synonymous_variant 0.26
thyX 3067631 c.315C>G synonymous_variant 0.26
thyX 3067634 c.312C>G synonymous_variant 0.26
thyX 3067652 c.294T>C synonymous_variant 0.26
thyX 3067661 c.285C>G synonymous_variant 0.26
thyX 3067685 c.261A>C synonymous_variant 0.21
thyX 3067691 p.Ile85Leu missense_variant 0.21
thyX 3067694 c.252G>C synonymous_variant 0.21
thyX 3067718 c.228C>G synonymous_variant 0.19
thyX 3067721 c.225T>C synonymous_variant 0.19
thyX 3067762 c.184C>A synonymous_variant 0.13
thyX 3067765 p.Leu61Ile missense_variant 0.13
thyX 3067772 c.174C>G synonymous_variant 0.14
thyX 3067781 c.165C>A synonymous_variant 0.18
thyX 3067793 c.153T>C synonymous_variant 0.16
thyX 3067799 c.147G>A synonymous_variant 0.17
thyX 3067802 c.144C>G synonymous_variant 0.2
thyX 3067814 c.132T>C synonymous_variant 0.22
thyX 3067850 c.96A>C synonymous_variant 0.29
thyX 3067869 p.Thr26Ser missense_variant 0.28
thyX 3067874 c.72C>G synonymous_variant 0.29
thyX 3067883 c.63C>G synonymous_variant 0.26
thyX 3067886 c.60A>C synonymous_variant 0.23
thyX 3067889 c.57C>G synonymous_variant 0.23
thyX 3067898 p.Asp16Glu missense_variant 0.21
thyX 3067935 p.Thr4Ile missense_variant 0.15
ald 3086742 c.-78A>C upstream_gene_variant 0.96
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3877848 c.660C>T synonymous_variant 0.13
rpoA 3877857 c.651G>A synonymous_variant 0.16
rpoA 3877866 c.642G>C synonymous_variant 0.18
rpoA 3877875 c.633T>G synonymous_variant 0.14
rpoA 3877878 c.630G>C synonymous_variant 0.14
rpoA 3877890 c.618C>T synonymous_variant 0.17
rpoA 3877896 c.612G>C synonymous_variant 0.16
rpoA 3877900 p.Ser203Asn missense_variant 0.14
rpoA 3877905 c.603A>G synonymous_variant 0.14
rpoA 3877920 c.588G>C synonymous_variant 0.15
rpoA 3877923 c.585C>T synonymous_variant 0.14
rpoA 3877926 c.582G>C synonymous_variant 0.14
rpoA 3877962 c.546G>T synonymous_variant 0.14
rpoA 3878391 c.117T>C synonymous_variant 0.13
rpoA 3878683 c.-176G>C upstream_gene_variant 0.14
clpC1 4038356 c.2349T>C synonymous_variant 0.23
clpC1 4038359 c.2346A>G synonymous_variant 0.22
clpC1 4038368 c.2337T>C synonymous_variant 0.21
clpC1 4038388 c.2317T>C synonymous_variant 0.23
clpC1 4038392 c.2313C>T synonymous_variant 0.21
clpC1 4038398 c.2307G>T synonymous_variant 0.21
clpC1 4038403 c.2302T>C synonymous_variant 0.2
clpC1 4038407 c.2298G>C synonymous_variant 0.25
clpC1 4038419 c.2286T>C synonymous_variant 0.21
clpC1 4038433 c.2272C>T synonymous_variant 0.17
clpC1 4038434 c.2271G>A synonymous_variant 0.17
clpC1 4038456 p.Val750Glu missense_variant 0.16
clpC1 4038460 p.Leu749Met missense_variant 0.16
clpC1 4038486 p.Gly740Asn missense_variant 0.14
clpC1 4038489 p.Ala739Gly missense_variant 0.14
clpC1 4038494 c.2211G>C synonymous_variant 0.14
clpC1 4038498 p.Ser736His missense_variant 0.14
clpC1 4038530 p.Glu725Asp missense_variant 0.15
clpC1 4038596 c.2109A>G synonymous_variant 0.22
clpC1 4038623 c.2082A>G synonymous_variant 0.18
clpC1 4038640 p.Asp689Asn missense_variant 0.19
clpC1 4038653 c.2052C>T synonymous_variant 0.19
clpC1 4038671 c.2034T>C synonymous_variant 0.15
clpC1 4038683 c.2022T>C synonymous_variant 0.15
clpC1 4038695 c.2010C>G synonymous_variant 0.14
clpC1 4038953 c.1752A>G synonymous_variant 0.17
clpC1 4038956 c.1749T>C synonymous_variant 0.15
clpC1 4038971 c.1734T>C synonymous_variant 0.14
clpC1 4038974 c.1731T>C synonymous_variant 0.14
clpC1 4040291 c.414G>C synonymous_variant 0.15
clpC1 4040318 c.387C>G synonymous_variant 0.13
embC 4241501 p.Ser547Thr missense_variant 0.13
embC 4241506 c.1644G>C synonymous_variant 0.13
embC 4241518 c.1656A>G synonymous_variant 0.14
embC 4241521 c.1659T>C synonymous_variant 0.15
embC 4241536 c.1674A>G synonymous_variant 0.17
embC 4241539 c.1677T>C synonymous_variant 0.17
embC 4241545 c.1683T>C synonymous_variant 0.17
embC 4241548 c.1686T>C synonymous_variant 0.16
embC 4241551 c.1689A>G synonymous_variant 0.17
embC 4241567 p.Ile569Val missense_variant 0.24
embC 4241572 c.1710C>G synonymous_variant 0.2
embC 4241578 c.1716G>C synonymous_variant 0.2
embC 4241584 c.1722T>C synonymous_variant 0.22
embC 4241587 c.1725C>G synonymous_variant 0.17
embC 4241591 p.Leu577Val missense_variant 0.22
embC 4241611 c.1749G>C synonymous_variant 0.24
embC 4241614 c.1752A>C synonymous_variant 0.24
embC 4241626 c.1764T>C synonymous_variant 0.21
embC 4241635 c.1773G>C synonymous_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242859 c.-374C>T upstream_gene_variant 0.14
embA 4242862 c.-371A>G upstream_gene_variant 0.14
embC 4242863 p.Tyr1001Asn missense_variant 0.15
embA 4242883 c.-350C>G upstream_gene_variant 0.14
embA 4244516 c.1284G>C synonymous_variant 0.14
embA 4244517 p.Leu429Val missense_variant 0.14
embA 4244523 p.Pro431Ala missense_variant 0.14
embA 4244534 c.1302T>C synonymous_variant 0.16
embA 4244537 c.1305T>G synonymous_variant 0.16
embA 4244543 c.1311C>G synonymous_variant 0.14
embA 4245182 c.1950T>C synonymous_variant 0.15
embA 4245198 p.Leu656Ile missense_variant 0.13
embA 4245207 c.1975T>C synonymous_variant 0.18
embA 4245215 c.1983A>C synonymous_variant 0.18
embA 4245222 p.Tyr664Gln missense_variant 0.16
embA 4245248 c.2016G>C synonymous_variant 0.18
embA 4245257 c.2025A>G synonymous_variant 0.2
embA 4245263 c.2031A>G synonymous_variant 0.16
embA 4245282 p.Ile684Val missense_variant 0.14
embA 4245290 c.2058C>G synonymous_variant 0.15
embA 4245293 c.2061T>G synonymous_variant 0.16
embA 4245296 c.2064G>C synonymous_variant 0.16
embA 4245299 c.2067A>G synonymous_variant 0.15
embB 4246544 p.Thr11Pro missense_variant 0.13
embB 4249594 c.3081G>A synonymous_variant 0.95
aftB 4268081 c.756A>G synonymous_variant 0.17
aftB 4268084 c.753G>C synonymous_variant 0.17
aftB 4268096 c.741C>G synonymous_variant 0.14
aftB 4268099 c.738G>C synonymous_variant 0.14
aftB 4268102 c.735C>G synonymous_variant 0.14
aftB 4268193 p.Leu215Ala missense_variant 0.13
ethA 4328376 c.-903G>C upstream_gene_variant 0.91
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
PPE35 2167033 c.343_*615del stop_lost&conservative_inframe_deletion&splice_region_variant 1.0