TB-Profiler result

Run: ERR1199001
Summary

Run ID: ERR1199001

Sample name:

Date: 15-08-2022 10:10:54

Number of reads: 5080064

Percentage reads mapped: 43.68

Strain: lineage4.6.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.1 Euro-American (Uganda) T2 RD724 1.0
lineage4.6.1.1 Euro-American T2-Uganda RD724 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7539 p.Thr80Ala missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 762836 c.-534C>G upstream_gene_variant 0.21
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471853 n.8T>C non_coding_transcript_exon_variant 0.09
rrs 1471896 n.51T>C non_coding_transcript_exon_variant 0.52
rrs 1471900 n.55C>T non_coding_transcript_exon_variant 0.5
rrs 1471914 n.69A>G non_coding_transcript_exon_variant 0.19
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.3
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.51
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.52
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.81
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.41
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.19
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.27
rrs 1472378 n.533G>T non_coding_transcript_exon_variant 0.66
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.65
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.65
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.35
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.32
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.34
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.51
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.55
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.22
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.12
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.51
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.62
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.65
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.76
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.66
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.49
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.15
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.61
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.4
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.29
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.25
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.14
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.13
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.17
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.61
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.19
rrl 1474236 n.579G>A non_coding_transcript_exon_variant 0.23
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.24
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.24
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.38
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.21
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.6
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.64
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.32
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.12
rrl 1475363 n.1706C>A non_coding_transcript_exon_variant 0.18
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.13
rrl 1475550 n.1893A>C non_coding_transcript_exon_variant 0.23
rrl 1475552 n.1895G>C non_coding_transcript_exon_variant 0.3
rrl 1475574 n.1917C>A non_coding_transcript_exon_variant 0.49
rrl 1475707 n.2050T>A non_coding_transcript_exon_variant 0.12
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 0.13
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 0.14
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.34
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.38
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.58
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.59
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.56
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.46
rrl 1475871 n.2214T>C non_coding_transcript_exon_variant 0.37
rrl 1476048 n.2392dupC non_coding_transcript_exon_variant 1.0
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.12
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.26
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.27
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.51
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.85
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.77
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.45
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.12
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.65
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.69
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.67
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.73
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.74
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.75
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.9
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.78
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.75
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.75
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.86
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.82
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.46
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.31
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169320 p.Leu431Phe missense_variant 0.2
PPE35 2169866 c.747G>C synonymous_variant 0.19
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyA 3073806 c.666C>G synonymous_variant 0.13
fbiD 3339153 p.Leu12Phe missense_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4038857 c.1848C>A synonymous_variant 0.21
clpC1 4039363 p.Ala448Pro missense_variant 0.16
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267967 c.870G>A synonymous_variant 1.0
ethA 4328329 c.-856C>G upstream_gene_variant 1.0
whiB6 4338591 c.-70G>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0