TB-Profiler result

Run: ERR192070
Summary

Run ID: ERR192070

Sample name:

Date: 31-03-2023 15:33:15

Number of reads: 126939

Percentage reads mapped: 3.78

Strain:

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5752 c.513G>A synonymous_variant 1.0
gyrA 6406 c.-896C>T upstream_gene_variant 1.0
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8285 c.984C>T synonymous_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoC 764575 c.1206T>G synonymous_variant 0.29
rpoC 764581 c.1212T>C synonymous_variant 0.29
rpoC 764582 p.Leu405Met missense_variant 0.29
rpoC 764602 c.1233C>T synonymous_variant 0.63
rpoC 764605 c.1236G>C synonymous_variant 0.63
rpoC 764611 c.1242G>T synonymous_variant 0.65
rpoC 764632 c.1263T>C synonymous_variant 0.65
rpoC 764641 c.1272C>T synonymous_variant 0.65
rpoC 764644 c.1275G>C synonymous_variant 0.65
rpoC 764647 c.1278C>T synonymous_variant 0.65
rpoC 764650 c.1281G>T synonymous_variant 0.65
rpoC 764659 c.1290C>T synonymous_variant 0.67
rpoC 764663 p.Val432Thr missense_variant 0.65
rpoC 764668 c.1299C>T synonymous_variant 0.68
rpoC 764672 p.Gln435Glu missense_variant 0.68
rpoC 764695 c.1326T>C synonymous_variant 0.58
rpoC 764701 c.1332C>G synonymous_variant 0.56
rpoC 764705 p.Leu446Lys missense_variant 0.5
rpoC 764908 c.1539G>A synonymous_variant 0.6
rpoC 764911 c.1542A>C synonymous_variant 0.6
rpoC 764913 p.Met515Thr missense_variant 0.6
rpoC 764918 p.Val517Ile missense_variant 0.6
rpoC 764932 c.1563C>T synonymous_variant 0.6
rpoC 764935 c.1566T>C synonymous_variant 0.6
rpoC 764944 c.1575C>T synonymous_variant 0.6
rpoC 764948 c.1579_1581delTTGinsCTC synonymous_variant 0.6
rpoC 764953 c.1584G>T synonymous_variant 0.6
rpoC 764957 p.Glu530Thr missense_variant 0.75
rpoC 764968 c.1599T>C synonymous_variant 0.5
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
fbiC 1304159 p.Val410Gly missense_variant 0.67
fbiC 1304166 c.1236A>G synonymous_variant 0.5
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.98
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.98
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 0.98
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.98
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.98
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.98
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.98
rrs 1472264 n.419T>C non_coding_transcript_exon_variant 0.97
rrs 1472266 n.421C>A non_coding_transcript_exon_variant 0.97
rrs 1472277 n.432C>G non_coding_transcript_exon_variant 0.97
rrs 1472338 n.493A>C non_coding_transcript_exon_variant 0.92
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.92
rrs 1472349 n.504A>T non_coding_transcript_exon_variant 1.0
rrs 1472374 n.529T>A non_coding_transcript_exon_variant 0.92
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.92
rrs 1472382 n.537G>T non_coding_transcript_exon_variant 0.92
rrs 1472391 n.546C>T non_coding_transcript_exon_variant 0.92
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.92
rrs 1472412 n.567A>C non_coding_transcript_exon_variant 0.91
rrs 1472415 n.570T>A non_coding_transcript_exon_variant 0.91
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 1.0
rrs 1472544 n.699C>T non_coding_transcript_exon_variant 1.0
rrs 1472545 n.700A>C non_coding_transcript_exon_variant 1.0
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 1.0
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 1.0
rrs 1472574 n.729T>A non_coding_transcript_exon_variant 1.0
rrs 1472579 n.734G>A non_coding_transcript_exon_variant 1.0
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 1.0
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 1.0
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 1.0
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 1.0
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 1.0
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 1.0
rrs 1472712 n.867G>A non_coding_transcript_exon_variant 1.0
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 1.0
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 1.0
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 1.0
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 1.0
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 1.0
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 1.0
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.98
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.98
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.97
rrs 1472812 n.967A>C non_coding_transcript_exon_variant 0.97
rrs 1472887 n.1042G>C non_coding_transcript_exon_variant 0.67
rrs 1473162 n.1317C>G non_coding_transcript_exon_variant 1.0
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 1.0
rrs 1473164 n.1319C>G non_coding_transcript_exon_variant 1.0
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 1.0
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 1.0
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 1.0
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 1.0
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 1.0
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.67
rrl 1475685 n.2028T>G non_coding_transcript_exon_variant 0.57
rrl 1475687 n.2030C>T non_coding_transcript_exon_variant 0.57
rrl 1475688 n.2031G>C non_coding_transcript_exon_variant 0.57
rrl 1475707 n.2050T>C non_coding_transcript_exon_variant 0.57
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 0.57
rrl 1475716 n.2059A>T non_coding_transcript_exon_variant 0.57
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 0.92
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.95
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.95
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.95
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.95
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.57
rrl 1476238 n.2581T>C non_coding_transcript_exon_variant 0.86
rrl 1476246 n.2589G>A non_coding_transcript_exon_variant 0.93
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.94
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.95
rrl 1476266 n.2609G>A non_coding_transcript_exon_variant 0.95
rrl 1476279 n.2622G>T non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 1.0
rrl 1476281 n.2624T>A non_coding_transcript_exon_variant 1.0
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.95
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 1.0
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 1.0
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 1.0
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 1.0
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 1.0
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 1.0
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>G non_coding_transcript_exon_variant 0.99
rrl 1476356 n.2699C>G non_coding_transcript_exon_variant 0.99
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 0.99
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.99
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.99
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.99
rrl 1476404 n.2747G>A non_coding_transcript_exon_variant 0.99
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.99
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.97
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.97
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.95
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.95
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.98
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.97
rrl 1476474 n.2817C>T non_coding_transcript_exon_variant 0.97
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.97
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.92
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.83
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.6
inhA 1674721 p.Phe174Leu missense_variant 0.29
ndh 2103173 c.-132delG upstream_gene_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2156025 c.87C>A synonymous_variant 1.0
katG 2156331 c.-220A>T upstream_gene_variant 0.25
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168319 p.Thr765Ile missense_variant 1.0
PPE35 2168721 p.Ala631Asp missense_variant 0.5
PPE35 2168814 c.1798dupA frameshift_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2518595 p.Arg161Ser missense_variant 0.4
eis 2714569 p.Ala255Gly missense_variant 1.0
eis 2715064 p.Thr90Met missense_variant 0.33
eis 2715125 p.Thr70Ala missense_variant 1.0
pepQ 2859754 p.Phe222Ser missense_variant 1.0
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
Rv3083 3448783 p.Val94Ile missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474427 p.Val141Ile missense_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
rpoA 3878630 c.-124delC upstream_gene_variant 1.0
clpC1 4038403 c.2302T>C synonymous_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4242680 p.Ala940Ser missense_variant 1.0
embA 4242970 c.-263C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4246551 p.Asn13Ser missense_variant 1.0
embB 4246864 c.351C>T synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
aftB 4267858 p.Ile327Val missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ethA 4328425 c.-952C>A upstream_gene_variant 0.4
gid 4407588 c.615A>G synonymous_variant 1.0