TB-Profiler result

Run: ERR323035
Summary

Run ID: ERR323035

Sample name:

Date: 01-04-2023 00:48:02

Number of reads: 21784

Percentage reads mapped: 0.38

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 762206 c.2400C>G synonymous_variant 0.83
rpoB 762209 c.2403C>G synonymous_variant 0.83
rpoB 762218 c.2412T>C synonymous_variant 0.83
rpoB 762243 p.Arg813Lys missense_variant 0.83
rpoB 762251 c.2445G>C synonymous_variant 0.83
rpoB 762254 c.2448T>C synonymous_variant 1.0
rpoB 762266 c.2460T>C synonymous_variant 1.0
rpoB 762275 c.2469C>G synonymous_variant 1.0
rpoB 762276 p.Arg824Ser missense_variant 1.0
rpoB 762281 p.Glu825Asp missense_variant 1.0
rpoC 762917 c.-453C>G upstream_gene_variant 1.0
rpoC 762920 c.-450C>G upstream_gene_variant 1.0
rpoC 762923 c.-447C>G upstream_gene_variant 1.0
rpoB 762925 p.Thr1040Ile missense_variant 1.0
rpoC 762932 c.-438G>T upstream_gene_variant 1.0
rpoC 762936 c.-434_-432delTCGinsAGC upstream_gene_variant 1.0
rpoB 762939 p.Met1045Leu missense_variant 1.0
rpoB 762942 p.Ile1046Val missense_variant 1.0
rpoC 762947 c.-423C>G upstream_gene_variant 1.0
rpoC 762965 c.-405T>C upstream_gene_variant 0.89
rpoC 762980 c.-390T>C upstream_gene_variant 0.8
rpoC 762983 c.-387C>T upstream_gene_variant 0.8
rpoC 762989 c.-381G>C upstream_gene_variant 0.8
rpoC 762995 c.-375G>C upstream_gene_variant 0.8
rpoB 763005 p.Cys1067Val missense_variant 0.8
rpoC 763013 c.-357C>G upstream_gene_variant 0.8
rpoB 763014 p.Met1070Leu missense_variant 0.8
rpoB 763017 p.Gln1071Glu missense_variant 0.8
rpoC 763028 c.-342T>C upstream_gene_variant 0.8
rpoC 763031 c.-339T>A upstream_gene_variant 1.0
rpoC 764557 p.Asn396Lys missense_variant 1.0
rpoC 764560 c.1191T>G synonymous_variant 1.0
rpoC 764566 c.1197C>G synonymous_variant 1.0
rpoC 764575 c.1206T>C synonymous_variant 1.0
rpoC 764581 c.1212T>C synonymous_variant 1.0
rpoC 764582 p.Leu405Met missense_variant 1.0
rpoC 764587 c.1218C>G synonymous_variant 1.0
rpoC 764611 c.1242G>C synonymous_variant 1.0
rpoC 764632 c.1263T>C synonymous_variant 1.0
rpoC 764635 c.1266C>G synonymous_variant 1.0
rpoC 764641 c.1272C>T synonymous_variant 1.0
rpoC 764650 c.1281G>T synonymous_variant 1.0
rpoC 764653 c.1284G>C synonymous_variant 1.0
rpoC 764662 c.1293G>C synonymous_variant 1.0
rpoC 764668 c.1299C>G synonymous_variant 1.0
rpoC 764672 p.Gln435Glu missense_variant 1.0
rpoC 764677 c.1308C>G synonymous_variant 1.0
rpoC 764686 c.1317C>T synonymous_variant 1.0
rpoC 764695 c.1326T>C synonymous_variant 1.0
rpoC 764701 c.1332C>G synonymous_variant 1.0
rpoC 764705 p.Leu446Lys missense_variant 1.0
rpoC 764713 c.1344G>C synonymous_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.67
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.67
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 1.0
rrs 1472123 n.278A>G non_coding_transcript_exon_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 1.0
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 1.0
rrs 1472135 n.290C>T non_coding_transcript_exon_variant 1.0
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 1.0
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 1.0
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 1.0
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 1.0
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 1.0
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 1.0
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 1.0
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 1.0
rrs 1472256 n.411T>A non_coding_transcript_exon_variant 1.0
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 1.0
rrs 1472262 n.417C>T non_coding_transcript_exon_variant 1.0
rrs 1472269 n.424G>A non_coding_transcript_exon_variant 1.0
rrs 1472277 n.432C>G non_coding_transcript_exon_variant 1.0
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 1.0
rrs 1472338 n.493A>C non_coding_transcript_exon_variant 0.83
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.83
rrs 1472349 n.504A>T non_coding_transcript_exon_variant 0.86
rrs 1472374 n.529T>A non_coding_transcript_exon_variant 0.83
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.83
rrs 1472382 n.537G>T non_coding_transcript_exon_variant 0.83
rrs 1472390 n.545T>C non_coding_transcript_exon_variant 0.8
rrs 1472391 n.546C>T non_coding_transcript_exon_variant 0.8
rrs 1472398 n.553T>C non_coding_transcript_exon_variant 0.67
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.8
rrs 1472415 n.570T>G non_coding_transcript_exon_variant 0.75
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.75
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.67
rrs 1472534 n.689G>T non_coding_transcript_exon_variant 0.67
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.67
rrs 1472544 n.699C>T non_coding_transcript_exon_variant 0.86
rrs 1472545 n.700A>G non_coding_transcript_exon_variant 0.86
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.92
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.96
rrs 1472572 n.727T>G non_coding_transcript_exon_variant 0.96
rrs 1472573 n.728C>A non_coding_transcript_exon_variant 0.96
rrs 1472574 n.729T>G non_coding_transcript_exon_variant 0.96
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.96
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.96
rrs 1472585 n.740A>C non_coding_transcript_exon_variant 0.96
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.96
rrs 1472603 n.758A>C non_coding_transcript_exon_variant 0.93
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.96
rrs 1472716 n.871C>A non_coding_transcript_exon_variant 0.67
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.98
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 1.0
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.98
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.98
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.98
rrs 1472812 n.967A>C non_coding_transcript_exon_variant 0.97
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.86
rrs 1473038 n.1193A>C non_coding_transcript_exon_variant 0.6
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.6
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.5
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.6
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.6
rrl 1473838 n.181_182insC non_coding_transcript_exon_variant 1.0
rrl 1473843 n.186G>C non_coding_transcript_exon_variant 1.0
rrl 1473851 n.194G>C non_coding_transcript_exon_variant 1.0
rrl 1473871 n.214T>G non_coding_transcript_exon_variant 1.0
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 1.0
rrl 1473881 n.224A>C non_coding_transcript_exon_variant 1.0
rrl 1473883 n.226A>T non_coding_transcript_exon_variant 1.0
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 1.0
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 1.0
rrl 1473890 n.233T>A non_coding_transcript_exon_variant 1.0
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.67
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.67
rrl 1475066 n.1409C>A non_coding_transcript_exon_variant 1.0
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 1.0
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 1.0
rrl 1475080 n.1423G>T non_coding_transcript_exon_variant 1.0
rrl 1475092 n.1435A>T non_coding_transcript_exon_variant 1.0
rrl 1475106 n.1449G>C non_coding_transcript_exon_variant 1.0
rrl 1475109 n.1452C>A non_coding_transcript_exon_variant 1.0
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 1.0
rrl 1475122 n.1465C>G non_coding_transcript_exon_variant 1.0
rrl 1475132 n.1475T>C non_coding_transcript_exon_variant 1.0
rrl 1475136 n.1479G>C non_coding_transcript_exon_variant 1.0
rrl 1475137 n.1480A>C non_coding_transcript_exon_variant 1.0
rrl 1475791 n.2134A>G non_coding_transcript_exon_variant 1.0
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 1.0
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 1.0
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 1.0
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 1.0
rrl 1475878 n.2221T>C non_coding_transcript_exon_variant 1.0
rrl 1476266 n.2609G>A non_coding_transcript_exon_variant 1.0
rrl 1476279 n.2622G>C non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 1.0
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 1.0
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.88
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 1.0
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 1.0
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 1.0
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 1.0
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 1.0
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 1.0
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 1.0
rrl 1476339 n.2682G>A non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 1.0
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 1.0
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 1.0
rrl 1476417 n.2760T>C non_coding_transcript_exon_variant 0.99
rrl 1476443 n.2786G>C non_coding_transcript_exon_variant 0.99
rrl 1476455 n.2798C>G non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 1.0
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 1.0
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 1.0
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 1.0
rrl 1476573 n.2916A>C non_coding_transcript_exon_variant 1.0
rrl 1476588 n.2931A>G non_coding_transcript_exon_variant 1.0
rrl 1476595 n.2938C>G non_coding_transcript_exon_variant 1.0
rrl 1476602 n.2945G>C non_coding_transcript_exon_variant 1.0
rrl 1476611 n.2954T>C non_coding_transcript_exon_variant 1.0
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 1.0
rrl 1476621 n.2964C>A non_coding_transcript_exon_variant 1.0
rrl 1476624 n.2967T>G non_coding_transcript_exon_variant 1.0
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 1.0
rrl 1476645 n.2988A>G non_coding_transcript_exon_variant 1.0
ndh 2102832 p.Pro71Thr missense_variant 1.0
clpC1 4040021 c.684A>C synonymous_variant 1.0