TB-Profiler result

Run: ERR4819265
Summary

Run ID: ERR4819265

Sample name:

Date: 01-04-2023 16:00:55

Number of reads: 438410

Percentage reads mapped: 45.28

Strain: lineage4.3.4.1

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.4 Euro-American (LAM) LAM RD174 1.0
lineage4.3.4.1 Euro-American (LAM) LAM1;LAM2 RD174 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.1 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.7 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.19 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8715 p.Pro472Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 759608 c.-199C>T upstream_gene_variant 1.0
rpoB 762026 c.2220G>C synonymous_variant 0.33
rpoB 762051 p.His749Tyr missense_variant 0.44
rpoB 762057 p.Ile751Val missense_variant 0.5
rpoB 762062 c.2256T>C synonymous_variant 0.5
rpoB 762065 c.2259T>C synonymous_variant 0.33
rpoB 762071 p.Asp755Glu missense_variant 0.33
rpoB 762080 c.2274G>C synonymous_variant 0.4
rpoB 762085 p.Ala760Glu missense_variant 0.4
rpoB 762087 p.Glu761Lys missense_variant 0.18
rpoB 762110 c.2304G>C synonymous_variant 0.18
rpoB 762114 p.Ile770Val missense_variant 0.17
rpoB 762156 p.Val784Leu missense_variant 0.2
rpoC 762896 c.-474G>C upstream_gene_variant 0.25
rpoC 762929 c.-441G>C upstream_gene_variant 0.33
rpoC 762932 c.-438G>C upstream_gene_variant 0.22
rpoC 763043 c.-327G>C upstream_gene_variant 0.33
rpoC 763053 c.-317T>C upstream_gene_variant 0.4
rpoC 763067 c.-303C>G upstream_gene_variant 0.44
rpoC 763070 c.-300T>C upstream_gene_variant 0.5
rpoC 763073 c.-297C>T upstream_gene_variant 0.25
rpoB 763077 p.Val1091Thr missense_variant 0.5
rpoC 763103 c.-267G>C upstream_gene_variant 0.5
rpoC 763109 c.-261C>T upstream_gene_variant 0.5
rpoC 763115 c.-255T>C upstream_gene_variant 0.5
rpoB 763119 p.Asn1105Asp missense_variant 0.5
rpoC 763127 c.-243G>C upstream_gene_variant 0.5
rpoC 763133 c.-237G>C upstream_gene_variant 0.5
rpoC 763511 p.Cys48Gly missense_variant 0.2
rpoC 763517 p.Lys50Gln missense_variant 0.2
rpoC 763528 c.159G>C synonymous_variant 0.22
rpoC 763546 c.177A>G synonymous_variant 0.3
rpoC 763550 p.Tyr61Ala missense_variant 0.3
rpoC 763570 c.201G>C synonymous_variant 0.27
rpoC 763578 p.Phe70Tyr missense_variant 0.27
rpoC 763606 c.237C>T synonymous_variant 0.18
rpoC 763609 c.240C>G synonymous_variant 0.18
rpoC 763615 c.246G>C synonymous_variant 0.18
rpoC 763622 p.Ala85Ser missense_variant 0.18
rpoC 763675 c.306C>G synonymous_variant 0.17
rpoC 763699 c.330G>T synonymous_variant 0.4
rpoC 763708 c.339G>C synonymous_variant 0.4
rpoC 763714 c.345G>C synonymous_variant 0.4
rpoC 763717 c.348T>C synonymous_variant 0.4
rpoC 763718 p.Leu117Val missense_variant 0.4
rpoC 763723 c.354G>C synonymous_variant 0.4
rpoC 763724 p.Asp119Asn missense_variant 0.4
rpoC 763729 c.360G>C synonymous_variant 0.44
rpoC 763732 c.363C>G synonymous_variant 0.5
rpoC 763735 c.366G>C synonymous_variant 0.5
rpoC 763744 c.375G>C synonymous_variant 0.44
rpoC 763751 p.Ile128Val missense_variant 0.5
rpoC 763772 p.Val135Met missense_variant 0.38
rpoC 764602 c.1233C>T synonymous_variant 0.38
rpoC 764605 c.1236G>T synonymous_variant 0.44
rpoC 764611 c.1242G>T synonymous_variant 0.5
rpoC 764632 c.1263T>C synonymous_variant 0.4
rpoC 764647 c.1278C>T synonymous_variant 0.45
rpoC 764650 c.1281G>T synonymous_variant 0.55
rpoC 764653 c.1284G>C synonymous_variant 0.5
rpoC 764656 c.1287C>G synonymous_variant 0.33
rpoC 764662 c.1293G>C synonymous_variant 0.7
rpoC 764677 c.1308C>G synonymous_variant 0.6
rpoC 764678 p.Lys437Gln missense_variant 0.6
rpoC 764692 c.1323C>T synonymous_variant 0.2
rpoC 764706 p.Leu446Gln missense_variant 0.43
rpoC 764995 c.1626C>G synonymous_variant 1.0
rpoC 767227 c.3858G>A synonymous_variant 0.29
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781760 c.201T>C synonymous_variant 0.12
rpsL 781766 c.207C>T synonymous_variant 0.19
rpsL 781772 c.213C>T synonymous_variant 0.12
rpsL 781796 p.Met79Ile missense_variant 0.23
rpsL 781802 c.243G>C synonymous_variant 0.23
rpsL 781805 c.246G>T synonymous_variant 0.15
rpsL 781811 c.252C>T synonymous_variant 0.25
rpsL 781814 c.255C>T synonymous_variant 0.25
rpsL 781817 c.258G>T synonymous_variant 0.23
rpsL 781829 c.270G>C synonymous_variant 0.13
rpsL 781832 c.273T>C synonymous_variant 0.2
rpsL 781838 c.279G>T synonymous_variant 0.14
rplC 800924 p.Ile39Asn missense_variant 0.22
embR 1416946 c.402C>T synonymous_variant 0.2
embR 1417282 c.66T>A synonymous_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.13
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.33
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.79
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.21
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.2
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.63
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.71
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.66
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 1.0
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.25
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.63
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.53
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.35
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.52
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.41
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.75
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 1.0
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 1.0
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 1.0
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 1.0
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 1.0
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.55
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.25
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.56
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.6
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.66
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.71
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.16
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.68
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.7
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.62
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.49
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 1.0
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 1.0
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.2
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.69
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.67
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.58
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.33
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 1.0
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 1.0
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.43
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.4
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.6
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.6
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.75
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.75
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 1.0
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 1.0
rrs 1472687 n.842_843insC non_coding_transcript_exon_variant 1.0
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.75
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.14
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.59
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.63
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.33
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.64
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.66
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.63
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.12
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.6
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.34
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.65
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.64
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 1.0
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.37
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.18
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.32
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.46
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.32
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.9
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.83
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.13
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.95
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.96
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.13
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.38
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.15
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.31
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.87
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.4
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.46
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.97
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.93
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.93
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.93
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.38
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.51
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.97
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.85
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.94
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.82
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.94
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.94
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.94
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.4
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.88
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.58
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.47
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.92
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.11
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.93
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.62
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.63
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.54
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.53
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.6
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.78
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.64
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.62
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.8
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.17
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 1.0
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.91
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 1.0
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 1.0
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.5
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.5
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.71
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.71
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.29
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.86
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.75
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.25
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.57
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.5
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.5
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.57
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.22
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.29
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>G non_coding_transcript_exon_variant 0.83
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.71
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.86
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.8
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 1.0
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 0.75
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>C non_coding_transcript_exon_variant 1.0
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.5
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.75
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.67
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 1.0
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 1.0
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 1.0
rrl 1475518 n.1861A>G non_coding_transcript_exon_variant 1.0
rrl 1475521 n.1864T>C non_coding_transcript_exon_variant 1.0
rrl 1475526 n.1869C>T non_coding_transcript_exon_variant 1.0
rrl 1475529 n.1872A>G non_coding_transcript_exon_variant 1.0
rrl 1475532 n.1875A>T non_coding_transcript_exon_variant 1.0
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 1.0
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 1.0
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 1.0
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.29
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 1.0
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 1.0
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.86
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.25
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.38
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.38
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.62
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.62
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.88
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.6
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.5
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.44
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.43
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.86
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 1.0
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.67
rrl 1475992 n.2335T>G non_coding_transcript_exon_variant 1.0
rrl 1475995 n.2338G>T non_coding_transcript_exon_variant 1.0
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.67
rrl 1475999 n.2342G>A non_coding_transcript_exon_variant 1.0
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 1.0
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.4
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.6
rrl 1476164 n.2507A>T non_coding_transcript_exon_variant 0.5
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.57
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 1.0
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.62
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.56
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.25
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.83
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.83
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.5
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.5
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.5
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.5
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.2
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.22
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.75
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.75
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.25
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.25
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.75
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.8
rrl 1476326 n.2669T>C non_coding_transcript_exon_variant 0.29
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.18
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.17
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.12
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.8
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.14
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.86
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.12
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.81
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.51
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.64
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.83
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.77
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.75
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.33
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.67
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.38
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.8
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.5
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.8
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.83
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.5
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.62
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.83
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.67
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.4
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.5
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.5
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.75
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.75
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.75
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.75
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.67
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.75
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.5
inhA 1674042 c.-160G>A upstream_gene_variant 0.22
rpsA 1834195 c.654G>C synonymous_variant 0.17
rpsA 1834234 c.693G>C synonymous_variant 0.28
rpsA 1834240 c.699T>C synonymous_variant 0.29
rpsA 1834249 c.708T>C synonymous_variant 0.39
rpsA 1834258 c.717G>A synonymous_variant 0.16
rpsA 1834261 c.720A>G synonymous_variant 0.42
rpsA 1834264 c.723G>C synonymous_variant 0.35
rpsA 1834294 c.753G>C synonymous_variant 0.47
rpsA 1834298 p.Gln253Glu missense_variant 0.47
rpsA 1834306 c.765T>C synonymous_variant 0.44
rpsA 1834307 p.Asp256Gln missense_variant 0.44
rpsA 1834312 c.771G>A synonymous_variant 0.44
rpsA 1834327 c.786G>T synonymous_variant 0.5
rpsA 1834345 c.804C>T synonymous_variant 0.36
rpsA 1834348 c.807T>C synonymous_variant 0.4
rpsA 1834354 c.813G>C synonymous_variant 0.44
rpsA 1834361 c.820T>C synonymous_variant 0.25
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169090 p.Val508Ala missense_variant 0.2
PPE35 2169419 c.1194C>T synonymous_variant 0.2
PPE35 2170177 p.Leu146Met missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2725969 c.-224_-223insG upstream_gene_variant 1.0
ahpC 2726323 p.Pro44Arg missense_variant 1.0
pepQ 2859830 p.Gly197Arg missense_variant 1.0
Rv2752c 3065374 p.Ala273Val missense_variant 0.29
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087044 c.225A>G synonymous_variant 0.12
ald 3087518 c.699C>T synonymous_variant 1.0
Rv3083 3448545 c.42A>T synonymous_variant 0.14
Rv3083 3448598 p.Ile32Thr missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474643 p.Arg213Cys missense_variant 0.12
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
Rv3236c 3612768 p.Ala117Pro missense_variant 1.0
alr 3840472 p.Gly317Ser missense_variant 0.2
alr 3841006 p.Asp139His missense_variant 1.0
clpC1 4038278 c.2427T>C synonymous_variant 0.33
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4039831 c.874T>C synonymous_variant 0.33
clpC1 4039838 p.Leu289Ile missense_variant 0.33
clpC1 4039850 c.855T>C synonymous_variant 0.33
clpC1 4039865 c.840T>C synonymous_variant 0.33
clpC1 4039875 p.Asn277Arg missense_variant 0.25
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245204 p.Gly658Arg missense_variant 0.14
embB 4246848 p.Gln112Arg missense_variant 0.15
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0