TB-Profiler result

Run: ERR7801314
Summary

Run ID: ERR7801314

Sample name:

Date: 02-04-2023 06:10:07

Number of reads: 3056148

Percentage reads mapped: 76.17

Strain: lineage4.3.4.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.4 Euro-American (LAM) LAM RD174 1.0
lineage4.3.4.2 Euro-American (LAM) LAM1;LAM4;LAM11 RD174 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 761707 p.Asp634Gly missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472089 n.244C>T non_coding_transcript_exon_variant 0.15
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.23
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.15
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.25
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.28
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.29
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.42
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.44
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.47
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.48
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.48
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.44
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.45
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.44
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.43
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.4
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.37
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.32
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.31
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.29
rrs 1472277 n.432C>A non_coding_transcript_exon_variant 0.12
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.28
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.38
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.39
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.39
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.39
rrs 1472678 n.833T>A non_coding_transcript_exon_variant 0.38
rrs 1472679 n.834T>C non_coding_transcript_exon_variant 0.38
rrs 1472681 n.837_841delTTGGG non_coding_transcript_exon_variant 0.4
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.39
rrs 1472697 n.852T>A non_coding_transcript_exon_variant 0.39
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.4
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.41
rrs 1472733 n.888G>C non_coding_transcript_exon_variant 0.42
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.41
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.4
rrs 1472742 n.897C>G non_coding_transcript_exon_variant 0.39
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.4
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.31
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.31
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.3
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.3
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.3
rrs 1473274 n.1429C>T non_coding_transcript_exon_variant 0.27
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.27
rrs 1473280 n.1435G>A non_coding_transcript_exon_variant 0.26
rrs 1473281 n.1436C>G non_coding_transcript_exon_variant 0.26
rrs 1473282 n.1437C>G non_coding_transcript_exon_variant 0.27
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.23
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.28
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.22
rrs 1473296 n.1451G>C non_coding_transcript_exon_variant 0.27
rrs 1473297 n.1452G>C non_coding_transcript_exon_variant 0.26
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.25
rrs 1473303 n.1458T>C non_coding_transcript_exon_variant 0.25
rrs 1473318 n.1473G>A non_coding_transcript_exon_variant 0.25
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.25
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.25
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.25
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.27
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.15
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.2
rrl 1476229 n.2572C>A non_coding_transcript_exon_variant 0.25
rrl 1476251 n.2594T>A non_coding_transcript_exon_variant 0.44
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.48
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.49
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.57
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.57
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.57
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.57
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.57
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.62
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.62
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.69
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.72
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.73
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.75
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.73
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.73
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.7
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.65
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.64
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.65
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.53
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.44
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.26
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.21
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3065293 p.Val300Ala missense_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 0.99
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 0.99
embC 4239763 c.-100C>T upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0